Read Books Online and Download eBooks, EPub, PDF, Mobi, Kindle, Text Full Free.
Structural And Functional Characterization Of Bacterial Secretion Systems Using Mass Spectrometry
Download Structural And Functional Characterization Of Bacterial Secretion Systems Using Mass Spectrometry full books in PDF, epub, and Kindle. Read online Structural And Functional Characterization Of Bacterial Secretion Systems Using Mass Spectrometry ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
Book Synopsis Structural and Functional Characterization of Bacterial Secretion Systems Using Mass Spectrometry by : Pragya Singh
Download or read book Structural and Functional Characterization of Bacterial Secretion Systems Using Mass Spectrometry written by Pragya Singh and published by . This book was released on 2011 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Structural and Functional Characterization of Bacterial Response and Neuroprotective Proteins by : Carey Anne Hobbs
Download or read book Structural and Functional Characterization of Bacterial Response and Neuroprotective Proteins written by Carey Anne Hobbs and published by . This book was released on 2009 with total page 213 pages. Available in PDF, EPUB and Kindle. Book excerpt: Keywords: Competence, NMR, Calbindin, response regulator, mass spectrometry, differential surface modification.
Book Synopsis Characterizing Bacterial Secretion Systems Using Mass Spectrometry by : Pragya Singh
Download or read book Characterizing Bacterial Secretion Systems Using Mass Spectrometry written by Pragya Singh and published by LAP Lambert Academic Publishing. This book was released on 2012-06 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gram-negative bacteria have evolved an array of secretion systems for protein transport across their membranes. The ability to secrete a diverse set of proteins to their target of choice provides bacteria with a menacing tool for pathogenesis. This work aims to enhance our understanding of bacterial pathogenesis by characterizing key aspects of bacterial secretion systems using mass spectrometry. Chapter 1 provides a general introduction of protein secretion pathways in Gran-negative bacteria, with a special emphasis on type III and type VI secretion systems. Chapter 2 highlights chemical cross-linking and mass spectrometry (CXMS) as a technique for studying protein-protein interactions in large molecular complexes. Chapter 3 describes a novel pipeline for acquisition and analysis of CXMS data. In Chapter 4, key interactions between the basal components of type III secretion systems (T3SS) are identified, and used to create a model of the core structure of T3SS. In Chapter 5, secretome of T6SS in P. aeruginosa is profiled to identify three novel substrates of the system. Evidence of the involvement of one of these substrates in inter-bacterial interactions is presented.
Book Synopsis Structural and Functional Characterization of Bacterial Cyclic-di-AMP Signaling Pathways by : Martina Müller
Download or read book Structural and Functional Characterization of Bacterial Cyclic-di-AMP Signaling Pathways written by Martina Müller and published by . This book was released on 2016 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Mycobacterial Cell Envelope by : Mamadou Daffé
Download or read book The Mycobacterial Cell Envelope written by Mamadou Daffé and published by . This book was released on 2008 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Explains the unique characteristics that cause this large group of bacteria responsible for tuberculosis and leprosy to function differently; serves as a valuable reference for those working in the areas of biochemistry, genetics, genomics, and immunology.
Book Synopsis Bacterial Secretion Systems by : Laure Journet
Download or read book Bacterial Secretion Systems written by Laure Journet and published by Springer Nature. This book was released on 2023-11-06 with total page 607 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second edition details new and updated protocols that cover techniques used to study secretion systems. Chapters focus on identifying and localizing the different subunits, defining interactions within subunits, monitoring conformational changes, purifying and imaging of large complexes, defining the assembly pathway by fluorescence microscopy and the role of energy during assembly and/or secretion, identifying secreted effectors as well as using reporters to follow effector transport. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Bacterial Secretion Systems: Methods and Protocols- Second Edition aims to be a useful and practical guide to new researchers and experts looking to expand their knowledge.
Book Synopsis Microbial Transport Systems by : Günther Winkelmann
Download or read book Microbial Transport Systems written by Günther Winkelmann and published by Wiley-VCH Verlag GmbH. This book was released on 2001 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: Transport of molecules across the cell membrane is a fundamental process of all living organisms. It is essential for understanding growth, development, nutrition as well as uptake and excretion of exogenous or synthesized molecules. Microbes respresent general and basic functional systems where many transport processes have been studied on a molecular basis. Knowledge of the microbial transport processes will provide new perspectives to treatments by inhibitors, drugs, antibiotics, vitamins, growth promotion compounds, activators and toxic compunds of various kinds.
Book Synopsis Molecular Biology of The Cell by : Bruce Alberts
Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Social Biology of Microbial Communities by : Institute of Medicine
Download or read book The Social Biology of Microbial Communities written by Institute of Medicine and published by National Academies Press. This book was released on 2013-01-10 with total page 633 pages. Available in PDF, EPUB and Kindle. Book excerpt: Beginning with the germ theory of disease in the 19th century and extending through most of the 20th century, microbes were believed to live their lives as solitary, unicellular, disease-causing organisms . This perception stemmed from the focus of most investigators on organisms that could be grown in the laboratory as cellular monocultures, often dispersed in liquid, and under ambient conditions of temperature, lighting, and humidity. Most such inquiries were designed to identify microbial pathogens by satisfying Koch's postulates.3 This pathogen-centric approach to the study of microorganisms produced a metaphorical "war" against these microbial invaders waged with antibiotic therapies, while simultaneously obscuring the dynamic relationships that exist among and between host organisms and their associated microorganisms-only a tiny fraction of which act as pathogens. Despite their obvious importance, very little is actually known about the processes and factors that influence the assembly, function, and stability of microbial communities. Gaining this knowledge will require a seismic shift away from the study of individual microbes in isolation to inquiries into the nature of diverse and often complex microbial communities, the forces that shape them, and their relationships with other communities and organisms, including their multicellular hosts. On March 6 and 7, 2012, the Institute of Medicine's (IOM's) Forum on Microbial Threats hosted a public workshop to explore the emerging science of the "social biology" of microbial communities. Workshop presentations and discussions embraced a wide spectrum of topics, experimental systems, and theoretical perspectives representative of the current, multifaceted exploration of the microbial frontier. Participants discussed ecological, evolutionary, and genetic factors contributing to the assembly, function, and stability of microbial communities; how microbial communities adapt and respond to environmental stimuli; theoretical and experimental approaches to advance this nascent field; and potential applications of knowledge gained from the study of microbial communities for the improvement of human, animal, plant, and ecosystem health and toward a deeper understanding of microbial diversity and evolution. The Social Biology of Microbial Communities: Workshop Summary further explains the happenings of the workshop.
Book Synopsis Difference Gel Electrophoresis by : Kay Ohlendieck
Download or read book Difference Gel Electrophoresis written by Kay Ohlendieck and published by Springer Nature. This book was released on 2022-11-15 with total page 477 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of this volume provides a comprehensive update of this key method on gel-based proteomics. Chapters present an introduction into the development of methods on principles of differential protein labeling and two-dimensional gel electrophoresis, techniques on optimized proteomic workflows using advanced mass spectrometry for protein identification, and the application of those methods in basic biological research, pathobiology and applied biomarker discovery. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Difference Gel Electrophoresis: Methods and Protocols, Second Edition aims to ensure successful results in the further study of this vital field.
Book Synopsis Bacterial Protein Toxins by : K. Aktories
Download or read book Bacterial Protein Toxins written by K. Aktories and published by Springer Science & Business Media. This book was released on 2013-03-14 with total page 713 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years remarkable progress has been accomplished with respect to our knowledge about bacterial protein toxins. This refers especially to structural aspects of protein toxins but also holds true for genetics, molecular biology and biochemical mechanisms underlying the action of toxins. This volume covers the very current and exciting aspects of up-to-date bacterial toxicology and comprehensively reviews the most important bacterial protein toxins such as the intracellular acting toxins which exhibit enzyme activity, as well as those toxins that interact with cell plasma membranes by damaging the membranes (pore formation) or stimulating cell receptors (superantigens). This is the most current reference work on these important bacterial protein toxins, which are presented from the point of view of different disciplines such as pharmacology, microbiology, cell biology and protein chemistry.
Book Synopsis Protein Secretion in Bacteria by : Maria Sandkvist
Download or read book Protein Secretion in Bacteria written by Maria Sandkvist and published by John Wiley & Sons. This book was released on 2020-07-02 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Protein transport into and across membranes is a fundamental process in bacteria that touches upon and unites many areas of microbiology, including bacterial cell physiology, adhesion and motility, nutrient scavenging, intrabacterial signaling and social behavior, toxin deployment, interbacterial antagonism and collaboration, host invasion and disruption, and immune evasion. A broad repertoire of mechanisms and macromolecular machines are required to deliver protein substrates across bacterial cell membranes for intended effects. Some machines are common to most, if not all bacteria, whereas others are specific to Gram-negative or Gram-positive species or species with unique cell envelope properties such as members of Actinobacteria and Spirochetes. Protein Secretion in Bacteria, authored and edited by an international team of experts, draws together the many distinct functions and mechanisms involved in protein translocation in one concise tome. This comprehensive book presents updated information on all aspects of bacterial protein secretion encompassing: Individual secretory systems–Sec, Tat, and T1SS through the newly discovered T9SS Mechanisms, structures, and functions of bacterial secretion systems Lipoprotein sorting pathways, outer membrane vesicles, and the sortase system Structures and roles of surface organelles, including flagella, pili, and curli Emerging technologies and translational implications Protein Secretion in Bacteria serves as both an introductory guide for students and postdocs and a ready reference for seasoned researchers whose work touches on protein export and secretion. This volume synthesizes the diversity of mechanisms of bacterial secretion across the microbial world into a digestible resource to stimulate new research, inspire continued identification and characterization of novel systems, and bring about new ways to manipulate these systems for biotechnological, preventative, and therapeutic applications.
Book Synopsis Protein Structure Prediction by : Daisuke Kihara
Download or read book Protein Structure Prediction written by Daisuke Kihara and published by Humana. This book was released on 2021-07-18 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: This thorough new edition explores web servers and software for protein structure prediction and modeling that are freely available to the academic community. Taking into account the numerous advances in the computational protein structure prediction/modeling field, the book includes residue-contact prediction via deep learning, a wide variety of protein docking models, as well as cryo-electron microscopy (cryo-EM) techniques. Written by renowned experts in the field and for the highly successful Methods in Molecular Biology series, chapters include the kind of key detail and implementation advice necessary for researchers to achieve optimal results in their own work. Authoritative and fully updated, Protein Structure Prediction, Fourth Edition is a practical and immediately useful guide for biology researchers working toward modeling protein structures./div/div/div/div/div/div/div/div/div/div/div/div/div/div/div/div/divdiv
Book Synopsis Bacterial Pili by : Michele A Barocchi
Download or read book Bacterial Pili written by Michele A Barocchi and published by CABI. This book was released on 2014-04-07 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bacterial pili play important roles as environmental sensors, in host colonization and in biofilm formation, enabling bacteria to interact with the environment, with surfaces and with other bacteria and host cells. Most bacteria, both Gram positive and Gram negative, and almost all bacterial pathogens, are piliated. This book discusses the synthesis, structure, evolution, function and role in pathogenesis of these complex structures, and their basis for vaccine development and therapeutics for Streptococcus pathogens. It is an invaluable resource for researchers and students of medical microbiology.
Book Synopsis Protein Secretion Pathways in Bacteria by : B. Oudega
Download or read book Protein Secretion Pathways in Bacteria written by B. Oudega and published by Springer. This book was released on 2012-09-13 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: For bacteria ..."the times are achanging"... The genomes of over 60 different bacteria have now been sequenced, and we know a lot about the important research organism Escherichia coli, the important industrial organism Bacillus subtilis, and about important plant and human pathogens. It will not take long before we know all the gene products and their functions of a few of these bacteria. Some of us already begin to think about a digital model E. coli or Bacillus cell. For that end we need to know all the physiological activities and metabolic routes of the cell. But in addition we like to know how things work at the molecular level and how protein and membranes as well as other (macromolecular) structures work together to carry out specific cell functions. Protein Secretion Pathways in Bacteria describes all the known folding and targeting routes of inner and outer membrane proteins as well as of proteins that are secreted by several specific export routes. The book gives detailed molecular information about the structures that are important for the different mechanisms involved. This is a valuable contribution to the understanding of how rather simple and yet complex bacterial cells work.
Book Synopsis Functional Analysis of Bacterial Genes by : Wolfgang Schumann (Prof. Dr. rer. nat.)
Download or read book Functional Analysis of Bacterial Genes written by Wolfgang Schumann (Prof. Dr. rer. nat.) and published by John Wiley & Sons. This book was released on 2001-02-08 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: Functional Analysis of Bacterial Genes: A Practical Manual summarises the principles and the key methods used to analyse the function of genes in bacteria. Written by members of the Bacillus subtilis Functional Analysis Consortium, this book provides a guide to the many approaches for the systematic analysis of gene function. Features include: * In-depth discussion of the theory and application of the methods * A step-by-step practical guide to each method * Experimental examples to indicate expected results * Contact information for suppliers and resource centres Written by internationally recognised authors, Functional Analysis of Bacterial Genes: A Practical Manual will be a valuable resource to researchers and technicians using functional analysis for many bacterial species, whether in the academic departments of microbiology or genetics, the biotechnology, biomedicine or pharmaceutical industries, or other centres of genomics and bioinformatics. "This volume, and the pioneering effort it represents, will be of interest not only to those of us who are specialists in B. subtilis but to all microbiologists and genome scientists who face the formidable task of uncovering the functions of the myriad uncharacterised genes that are emerging from large-scale sequencing." - Richard Losick , The Biological Laboratories, Harvard University, Cambridge, Massachusetts, USA
Book Synopsis Proteomics of Microbial Pathogens by : Peter R. Jungblut
Download or read book Proteomics of Microbial Pathogens written by Peter R. Jungblut and published by John Wiley & Sons. This book was released on 2007-01-30 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: High-quality research articles on proteomic analyses of microbial pathogens, made available in a handy form. Containing proven, high-quality research articles selected from the popular PROTEOMICS journal, this is a current overview of the latest research into the proteomics analysis of microbial pathogens as well as several review articles.
