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Structural Analysis Of Integral Membrane Proteins By Freeze Fracture Electron Microscopy
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Book Synopsis Structural Analysis of Integral Membrane Proteins by Freeze-fracture Electron Microscopy by : Sepehr Eskandari
Download or read book Structural Analysis of Integral Membrane Proteins by Freeze-fracture Electron Microscopy written by Sepehr Eskandari and published by . This book was released on 1999 with total page 446 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Membrane Proteins Production for Structural Analysis by : Isabelle Mus-Veteau
Download or read book Membrane Proteins Production for Structural Analysis written by Isabelle Mus-Veteau and published by Springer. This book was released on 2014-06-20 with total page 441 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book updates the latest development in production, stabilization and structural analysis techniques of membrane proteins. This field has made significant advances since the elucidation of the first 3-D structure of a recombinant G Protein Coupled Receptor (GPCR), rhodopsin, with the structure of several more GPCRs having been solved in the past five years. In fact, the 2012 Nobel Prize in Chemistry was awarded for groundbreaking discoveries on the inner workings of GPCRs. This book is essential reading for all researchers, biochemists and crystallographers working with membrane proteins, who are interested by the structural characterization of their favorite protein and who wish to follow the expression, migration, modifications and recycling of a membrane protein.
Book Synopsis Techniques for the Analysis of Membrane Proteins by : C. Ragan
Download or read book Techniques for the Analysis of Membrane Proteins written by C. Ragan and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 447 pages. Available in PDF, EPUB and Kindle. Book excerpt: A preface should justify the existence of the book it precedes and this is invariably done in scientific texts by reference to the explosive growth of the field since the last such volume appeared. In molecular biology, most fields can be justifiably described as growing explosively, as should be the case for a young and vigorous science, but the study of membrane proteins stands out as one which has taken giant strides in the last few years. Ignorance of the structure and function of membrane proteins at the molecular level was certainly not due to lack of interest but rather was a result of lack of appropriate techniques. It has above all been the development of new experimental methods which has wrenched membrane biochemistry out of what Anthony Martonosi fetchingly called its 'romantic phase' (Le. lots of ideas and few facts), into an era when the determination of membrane protein structure and mechanism is a reasonable goal. Membrane proteins are generally classified as peripheral or integral. Peripheral proteins are relatively easily dissociated from membranes by mild treatments whence their study is essentially no different to that of soluble proteins. This book therefore concentrates on integral proteins which are strongly bound to the membrane by hydrophobic interactions with lipids. A crucial step in their study is of necessity the d~velopment of methods of solubilization and purification under non-denaturing conditions.
Book Synopsis The Structural Analysis of Membrane Proteins as Determined by High Resolution Electron Microscopy by : E. Loren Buhle
Download or read book The Structural Analysis of Membrane Proteins as Determined by High Resolution Electron Microscopy written by E. Loren Buhle and published by . This book was released on 1984 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Structural Analysis of Membrane Proteins by Electron Microscopy by : Thomas Walz
Download or read book Structural Analysis of Membrane Proteins by Electron Microscopy written by Thomas Walz and published by . This book was released on 1996 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Freeze-Fracture Studies of Membranes by : Sek Wen Hui
Download or read book Freeze-Fracture Studies of Membranes written by Sek Wen Hui and published by CRC Press. This book was released on 2018-01-18 with total page 229 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is a kind of celebration of the progress of freeze-fracture electron microscopy in recent years. Many of the authors are leaders of the advancing front. Instead of offering an instruction manual of how to perform new techniques or a review to recover what has happened in the past in respect fields, both which are abundantly available as journal articles and monographs, this volume is a collection of personal testimonies as examples of the power of the new freeze-fracture technology. Since each chapter also centres around specific biological problem, it also serves to illustrate how much the understanding of the problem has been advanced by the new freeze-fracture methodology, which is most cases is developed by the author(s) themselves. A characteristic of frontier development is that many chapters are dealing with controversial subjects. The Inclusion of these subjects in the volume represents the dynamic nature of the subject as viewed by the authors rather than the final verdicts of the subject matter.
Book Synopsis Structural Analysis of Integral Membrane Proteins by : Uzi Kochva
Download or read book Structural Analysis of Integral Membrane Proteins written by Uzi Kochva and published by . This book was released on 2007 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Structural Analysis of Membrane Protein Biogenesis and Ribosome Stalling by Cryo-electron Microscopy by : Lukas Bischoff
Download or read book Structural Analysis of Membrane Protein Biogenesis and Ribosome Stalling by Cryo-electron Microscopy written by Lukas Bischoff and published by . This book was released on 2015 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Structural and Functional Characterization of the Integral Membrane Proteins CitS and CCR5 by Electron Microscopy by : Fabian Kebbel
Download or read book Structural and Functional Characterization of the Integral Membrane Proteins CitS and CCR5 by Electron Microscopy written by Fabian Kebbel and published by . This book was released on 2013 with total page 101 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Membrane Protein Purification, 2D-crystallization and Structural Analysis by Electron Microscopy by : Plodeck Jianping Zhuang
Download or read book Membrane Protein Purification, 2D-crystallization and Structural Analysis by Electron Microscopy written by Plodeck Jianping Zhuang and published by . This book was released on 1997 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Application of Electron Microscopy to the Structural Analysis of Photosynthetic Membrane Proteins by : Alevtyna Yakushevska
Download or read book Application of Electron Microscopy to the Structural Analysis of Photosynthetic Membrane Proteins written by Alevtyna Yakushevska and published by . This book was released on 2004 with total page 129 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Crystallization of Membrane Proteins by : Hartmut Michel
Download or read book Crystallization of Membrane Proteins written by Hartmut Michel and published by CRC Press. This book was released on 2018-01-18 with total page 343 pages. Available in PDF, EPUB and Kindle. Book excerpt: The precise knowledge of the structure of biological macromolecules forms the basis of understanding their function and their mechanism of action. It also lays the foundation for rational protein and drug design. The only method to obtain this knowledge is still crystallography. At present, the structures of about 400 proteins are known at or nearly at atomic proteins. However, only two of them are membrane proteins or complexes of the membrane proteins. The reasons for the difference is not the crystals of membrane proteins resists forming special problems when being analysed. The reason is that the membrane proteins resist into forming into well-ordered crystals. The intention of this book is to help to produce well-ordered crystals proteins and to provide guidelines, it is aimed at both biochemists and protein crystallographer‘s.
Book Synopsis The Next Generation in Membrane Protein Structure Determination by : Isabel Moraes
Download or read book The Next Generation in Membrane Protein Structure Determination written by Isabel Moraes and published by Springer. This book was released on 2016-08-23 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews current techniques used in membrane protein structural biology, with a strong focus on practical issues. The study of membrane protein structures not only provides a basic understanding of life at the molecular level but also helps in the rational and targeted design of new drugs with reduced side effects. Today, about 60% of the commercially available drugs target membrane proteins and it is estimated that nearly 30% of proteins encoded in the human genome are membrane proteins. In recent years much effort has been put towards innovative developments to overcome the numerous obstacles associated with the structure determination of membrane proteins. This book reviews a variety of recent techniques that are essential to any modern researcher in the field of membrane protein structural biology. The topics that are discussed are not commonly found in textbooks. The scope of this book includes: Expression screening using fluorescent proteins The use of detergents in membrane protein research The use of NMR Synchrotron developments in membrane protein structural biology Visualisation and X-ray data collection of microcrystals X-ray diffraction data analysis from multiple crystals Serial millisecond crystallography Serial femtosecond crystallography Membrane protein structures in drug discovery The information provided in this book should be of interest to anyone working in the area of structural biology. Students will find carefully prepared overviews of basic ideas and advanced protein scientists will find the level of detail required to apply the material directly to their day to day work. Chapters 4, 5, 6, 8 and 9 of this book are published open access under a CC BY 4.0 license at link.springer.com.
Book Synopsis Cell and Molecular Biology by : Gerald Karp
Download or read book Cell and Molecular Biology written by Gerald Karp and published by John Wiley & Sons. This book was released on 2009-10-19 with total page 836 pages. Available in PDF, EPUB and Kindle. Book excerpt: Karp continues to help biologists make important connections between key concepts and experimentation. The sixth edition explores core concepts in considerable depth and presents experimental detail when it helps to explain and reinforce the concepts. The majority of discussions have been modified to reflect the latest changes in the field. The book also builds on its strong illustration program by opening each chapter with “VIP” art that serves as a visual summary for the chapter. Over 60 new micrographs and computer-derived images have been added to enhance the material. Biologists benefit from these changes as they build their skills in making the connection.
Book Synopsis Membrane Protein Structure Determination by : Jean-Jacques Lacapère
Download or read book Membrane Protein Structure Determination written by Jean-Jacques Lacapère and published by Methods in Molecular Biology. This book was released on 2010-08-06 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: Membrane proteins, representing nearly 40% of all proteins, are key components of cells involved in many cellular processes, yet only a small number of their structures have been determined. Membrane Protein Structure Determination: Methods and Protocols presents many detailed techniques for membrane protein structure determination used today by bringing together contributions from top experts in the field. Divided into five convenient sections, the book covers various strategies to purify membrane proteins, approaches to get three dimensional crystals and solve the structure by x-ray diffraction, possibilities to gain structural information for a membrane protein using electron microscopy observations, recent advances in nuclear magnetic resonance (NMR), and molecular modelling strategies that can be used either to get membrane protein structures or to move from atomic structure to a dynamic understanding of a molecular functioning mechanism. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and easy to use, Membrane Protein Structure Determination: Methods and Protocols serves as an ideal reference for scientists seeking to further our knowledge of these vital and versatile proteins as well as our overall understanding of the complicated world of cell biology.
Book Synopsis Membrane Proteins – Engineering, Purification and Crystallization by :
Download or read book Membrane Proteins – Engineering, Purification and Crystallization written by and published by Academic Press. This book was released on 2015-04-30 with total page 663 pages. Available in PDF, EPUB and Kindle. Book excerpt: Membrane Proteins – Engineering, Purification and Crystallization, a volume of Methods In Enzymology, encompasses chapters from the leading experts in the area of membrane protein biology. The chapters provide a brief overview of the topics covered and also outline step-by-step protocol for the interested audience. Illustrations and case example images are included wherever appropriate to help the readers understand the schematics and general experimental outlines. Volume of Methods In Enzymology Contains a collection of a diverse array of topics in the area of membrane protein biology ranging from recombinant expression, isolation, functional characterization, biophysical studies and crystallization
