Stroke Genomics

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Stroke Genomics

Author : Simon J. Read
Publisher : Springer Science & Business Media
ISBN 13 : 1592598366
Total Pages : 352 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Stroke Genomics by : Simon J. Read

Download or read book Stroke Genomics written by Simon J. Read and published by Springer Science & Business Media. This book was released on 2008-02-01 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: With sequencing of the human genome now complete, deciphering the role of gene function in human neurological pathophysiology is a promise that has yet to be realized. More than most diseases, stroke has been keenly studied from a genomic perspective. Studies are numerous and incorporate data on stroke inheritance, chromosomal loci of risk, preclinical models of stroke, and differential gene expression of brain injury, repair, and recovery. The problem is no longer a lack of information but one of interpretation and prioritization of what we do know. The aims of Stroke Genomics: Methods and Reviews are twofold. First, it aims to provide the reader with cutting-edge reviews of clinical and preclinical genomics, written by leading experts in the field. In particular, the authors of certain chapters relate gene expression changes to physiological end points, such as functional imaging paradigms. Thus, a more holistic approach to gene expression is described, one in which molecular biology goes hand in hand with stroke pathophysiology. Second, detailed methods for study of the molecular biology of stroke are TM also included. Following the format of the Methods in Molecular Medicine series, these chapters will enable the reader to employ each technique without recourse to other methods texts. In its entirety, this book should provide the reader with the knowledge needed to design, execute, and interpret preclinical and clinical studies of stroke genomics.

Stroke Genetics

Author : Hugh S. Markus
Publisher :
ISBN 13 : 0198515863
Total Pages : 362 pages
Book Rating : 4.1/5 (985 download)

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Book Synopsis Stroke Genetics by : Hugh S. Markus

Download or read book Stroke Genetics written by Hugh S. Markus and published by . This book was released on 2003 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stroke is a major cause of death and the major cause of adult neurological disability in most of the world. Despite its importance on a population basis, research into the genetics of stroke has lagged behind that of many other disorders. However, the situation is now changing. An increasing number of single gene disorders causing stroke are being described, and there is growing evidence that polygenic factors are important in the risk of apparently "sporadic" stroke. Stroke Genetics provides an up-to-date review of the area, suitable for clinicians treating stroke patients, and both clinical and non-clinical researchers in the field of cerebrovascular disease. The full range of monogenic stroke disorders causing cerebrovascular disease, including ischaemic stroke, intracerebral haemorrhage, aneurysms and arteriovenous malformations, are covered. For each, clinical features, diagnosis, and genetics are described. Increasing evidence suggest that genetic factors are also important for the much more common multifactorial stroke; this evidence is reviewed along with the results of genetic studies in this area. Optimal and novel strategies for investigating multifactorial stroke, including the use of intermediate phenotypes such as intima-media thickness and MRI detected small vessel disease are reviewed. The book concludes by describing a practical approach to investigating patients with stroke for underlying genetic disorders. Also included is a list of useful websites.

Acute Stroke Nursing

Author : Jane Williams
Publisher : John Wiley & Sons
ISBN 13 : 1118699629
Total Pages : 367 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis Acute Stroke Nursing by : Jane Williams

Download or read book Acute Stroke Nursing written by Jane Williams and published by John Wiley & Sons. This book was released on 2013-05-07 with total page 367 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stroke is a medical emergency that requires immediate medical attention. With active and efficient nursing management in the initial hours after stroke onset and throughout subsequent care, effective recovery and rehabilitation is increased. Acute Stroke Nursing provides an evidence-based, practical text facilitating the provision of optimal stroke care during the primary prevention, acute and continuing care phases. This timely and comprehensive text is structured to follow the acute stroke pathway experienced by patients. It explores the causes, symptoms and effects of stroke, and provides guidance on issues such as nutrition, continence, positioning, mobility and carer support. The text also considers rehabilitation, discharge planning, palliative care and the role of the nurse within the multi-professional team. Acute Stroke Nursing is the definitive reference on acute stroke for all nurses and healthcare professionals wishing to extend their knowledge of stroke nursing. Evidence-based and practical in style, with case studies and practice examples throughout Edited and authored by recognised stroke nursing experts, clinicians and leaders in the field of nursing practice, research and education The first text to explore stroke management from UK and international perspectives, and with a nursing focus

Stroke Genetics

Author : Pankaj Sharma
Publisher : Springer Nature
ISBN 13 : 3031417771
Total Pages : 626 pages
Book Rating : 4.0/5 (314 download)

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Book Synopsis Stroke Genetics by : Pankaj Sharma

Download or read book Stroke Genetics written by Pankaj Sharma and published by Springer Nature. This book was released on with total page 626 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Stroke Genetics

Author : Pankaj Sharma
Publisher : Springer Science & Business Media
ISBN 13 : 0857292099
Total Pages : 333 pages
Book Rating : 4.8/5 (572 download)

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Book Synopsis Stroke Genetics by : Pankaj Sharma

Download or read book Stroke Genetics written by Pankaj Sharma and published by Springer Science & Business Media. This book was released on 2012-08-27 with total page 333 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the last decade there has been a substantial increase in our understanding of the genetic basis of common disorders such as stroke. Stroke Genetics is designed to give the reader an overall understanding of the genetics of complex diseases by using stroke as a paradigm. The reader will gain a comprehensive understanding of cerebrovascular genetics including the epidemiological evidence for the genetic basis of ischemic and hemorrhagic stroke, knowledge of its molecular basis from association, linkage and recent genome-wide studies, and also monogenic disorders. Finally, the legal and ethical complexities in dealing with these issues are discussed. Stroke Genetics benefits from the contribution of renowned experts from throughout the world who have been intimately involved in unraveling the genetic etiology of stroke. Stroke Genetics is a valuable resource for neurologists, stroke physicians, hypertension specialists, internists, clinical pharmacologists and those in training, as well as researchers in the field of disease genetics.

Non-Vitamin K Antagonist Oral Anticoagulants

Author : Eduard Shantsila
Publisher : Springer
ISBN 13 : 331925460X
Total Pages : 82 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis Non-Vitamin K Antagonist Oral Anticoagulants by : Eduard Shantsila

Download or read book Non-Vitamin K Antagonist Oral Anticoagulants written by Eduard Shantsila and published by Springer. This book was released on 2015-12-21 with total page 82 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is an essential guide to the medical treatment of thrombosis and presents core principles of anticoagulant therapeutics as well as drug recommendations. Written by recognized experts in the field, this concise, accessible handbook provides a unique and valuable resource in the cardiovascular field, both for those currently in training, and for those already in clinical or research practice.

Cardiovascular Genetics and Genomics

Author : Dhavendra Kumar
Publisher : Springer
ISBN 13 : 3319661140
Total Pages : 921 pages
Book Rating : 4.3/5 (196 download)

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Book Synopsis Cardiovascular Genetics and Genomics by : Dhavendra Kumar

Download or read book Cardiovascular Genetics and Genomics written by Dhavendra Kumar and published by Springer. This book was released on 2018-01-17 with total page 921 pages. Available in PDF, EPUB and Kindle. Book excerpt: This title reflects the exponential growth in the knowledge and information on this subject and defines the extensive clinical translation of cardiovascular genetics and genomics in clinical practice. This concise, clinically oriented text is targeted at a broad range of clinicians who manage patients and families with a wide range of heterogeneous inherited cardiovascular conditions. Cardiovascular Genetics and Genomics: Principles and Clinical Practice includes a concise and clear account on selected topics written by a team of leading experts on clinical cardiovascular genetics. Each chapter include key information to assist the clinician and case histories have been incorporated to reflect contemporary practice in clinical cardiovascular genetics and genomics. Therefore this will be of key importance to all professionals working in the discipline, from clinicians and trainees in cardiology, cardiac surgery, electrophysiology, immunology through geneticists, nursing staff and those involved in precision medicine.

Oxford Textbook of Stroke and Cerebrovascular Disease

Author : Bo Norrving
Publisher : Oxford University Press, USA
ISBN 13 : 019964120X
Total Pages : 306 pages
Book Rating : 4.1/5 (996 download)

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Book Synopsis Oxford Textbook of Stroke and Cerebrovascular Disease by : Bo Norrving

Download or read book Oxford Textbook of Stroke and Cerebrovascular Disease written by Bo Norrving and published by Oxford University Press, USA. This book was released on 2014 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: Part of the Oxford Textbooks in Clinical Neurology (OTCN) series, this practical volume covers the current pedagogic principles of stroke disease and care, including the acute hospital phase, public health issues, prevention, long-term management, and silent vascular disease.

Cardiovascular Genetics and Genomics

Author : Dan M. Roden
Publisher : John Wiley & Sons
ISBN 13 : 9781444311778
Total Pages : 288 pages
Book Rating : 4.3/5 (117 download)

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Book Synopsis Cardiovascular Genetics and Genomics by : Dan M. Roden

Download or read book Cardiovascular Genetics and Genomics written by Dan M. Roden and published by John Wiley & Sons. This book was released on 2009-04-01 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive and concise presentation of genetic factors in cardiovascular disease and their response to therapy consolidates knowledge of this high-interest and emerging topic. Covering broad areas of contemporary genomic medicine and specific cardiovascular diseases, this book is a must for anyone seeking to better understand this rapidly developing field.

Cerebral Small Vessel Disease

Author : Leonardo Pantoni
Publisher : Cambridge University Press
ISBN 13 : 1107031664
Total Pages : 375 pages
Book Rating : 4.1/5 (7 download)

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Book Synopsis Cerebral Small Vessel Disease by : Leonardo Pantoni

Download or read book Cerebral Small Vessel Disease written by Leonardo Pantoni and published by Cambridge University Press. This book was released on 2014-05 with total page 375 pages. Available in PDF, EPUB and Kindle. Book excerpt: Up-to-date discussion of the etiology, diagnosis, treatment, and prevention of this common cause of stroke and cognitive impairment.

Genetics and Genomics in Nursing and Health Care

Author : Theresa A Beery
Publisher : F.A. Davis
ISBN 13 : 0803660960
Total Pages : 457 pages
Book Rating : 4.8/5 (36 download)

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Book Synopsis Genetics and Genomics in Nursing and Health Care by : Theresa A Beery

Download or read book Genetics and Genomics in Nursing and Health Care written by Theresa A Beery and published by F.A. Davis. This book was released on 2018-01-08 with total page 457 pages. Available in PDF, EPUB and Kindle. Book excerpt: Complex concepts made manageable! Build the foundation you need to understand the science of genetics and its growing role in the diagnosis and treatment of diseases and disorders. Confidently tackle the basics of genetic inheritance, the influence of somatic and germline mutations, the multifactorial relationship of gene-environment interactions, and the foundation of ethical behavior. Everyday language makes these often-intimidating topics easy to understand, while clearly defined principles, logical explanations, illustrations, tables, and clinical examples ensure you master the material.

Women in Science: Genetics

Author : Rana Dajani
Publisher : Frontiers Media SA
ISBN 13 : 2832505260
Total Pages : 220 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Women in Science: Genetics by : Rana Dajani

Download or read book Women in Science: Genetics written by Rana Dajani and published by Frontiers Media SA. This book was released on 2022-11-11 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Genomic and Personalized Medicine

Author :
Publisher : Academic Press
ISBN 13 : 0123822289
Total Pages : 1342 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis Genomic and Personalized Medicine by :

Download or read book Genomic and Personalized Medicine written by and published by Academic Press. This book was released on 2012-10-30 with total page 1342 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genomic and Personalized Medicine, Second Edition — winner of a 2013 Highly Commended BMA Medical Book Award for Medicine — is a major discussion of the structure, history, and applications of the field, as it emerges from the campus and lab into clinical action. As with the first edition, leading experts review the development of the new science, the current opportunities for genome-based analysis in healthcare, and the potential of genomic medicine in future healthcare. The inclusion of the latest information on diagnostic testing, population screening, disease susceptability, and pharmacogenomics makes this work an ideal companion for the many stakeholders of genomic and personalized medicine. With advancing knowledge of the genome across and outside protein-coding regions of DNA, new comprehension of genomic variation and frequencies across populations, the elucidation of advanced strategic approaches to genomic study, and above all in the elaboration of next-generation sequencing, genomic medicine has begun to achieve the much-vaunted transformative health outcomes of the Human Genome Project, almost a decade after its official completion in April 2003. - Highly Commended 2013 BMA Medical Book Award for Medicine - More than 100 chapters, from leading researchers, review the many impacts of genomic discoveries in clinical action, including 63 chapters new to this edition - Discusses state-of-the-art genome technologies, including population screening, novel diagnostics, and gene-based therapeutics - Wide and inclusive discussion encompasses the formidable ethical, legal, regulatory and social challenges related to the evolving practice of genomic medicine - Clearly and beautifully illustrated with 280 color figures, and many thousands of references for further reading and deeper analysis

Emery and Rimoin's Essential Medical Genetics

Author : David L. Rimoin
Publisher : Elsevier
ISBN 13 : 0124169821
Total Pages : 647 pages
Book Rating : 4.1/5 (241 download)

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Book Synopsis Emery and Rimoin's Essential Medical Genetics by : David L. Rimoin

Download or read book Emery and Rimoin's Essential Medical Genetics written by David L. Rimoin and published by Elsevier. This book was released on 2013-05-15 with total page 647 pages. Available in PDF, EPUB and Kindle. Book excerpt: For decades, Emery and Rimoin’s Principles and Practice of Medical Genetics has provided the ultimate source for practicing clinicians to learn how the study of genetics can be integrated into practice. Developed in parallel to the sixth edition, and featuring 174 original contributions from the many authors of the full set, this one volume work expertly condenses and synthesizes the most clinically relevant content, for convenient desk reference. Helping to bridge the gap between high-level molecular genetics and individual application, it follows the multi-volume set in encompassing scientific fundamentals, full spectrum discussion of major inherited disorders, and actionable therapies. Clinically oriented information is supported by concise descriptions of the principles of genetics, research approaches, and analytics to embrace the evolving population of students, researchers, and practitioners who are integrating their work to provide advanced diagnosis, prevention and treatment of human disease. This print volume is complemented and enhanced with online access to the complete text, online-only references, and high quality illustrations on www.expertconsult.com. Features 174 summarized contributions concisely discussing advances in cancer genetics, genomic technologies, and molecular genetics Contains hundreds of full colour illustrations supporting users with identification, concept illustration, and method processing Enhanced with full text online access, high quality illustrations, and online-only references at www.expertconsult.com

Rational Basis for Clinical Translation in Stroke Therapy

Author : Giuseppe Micieli
Publisher : CRC Press
ISBN 13 : 1466594977
Total Pages : 542 pages
Book Rating : 4.4/5 (665 download)

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Book Synopsis Rational Basis for Clinical Translation in Stroke Therapy by : Giuseppe Micieli

Download or read book Rational Basis for Clinical Translation in Stroke Therapy written by Giuseppe Micieli and published by CRC Press. This book was released on 2014-08-27 with total page 542 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stroke remains one of the major causes of death and long-term disability worldwide. Currently, the only approved therapy for the acute treatment of this disease is thrombolysis, a strategy that can only be applied to a small percentage of patients due to its narrow therapeutic window. Unfortunately, during the last years numerous promising drugs that showed neuroprotection in the experimental setting failed to translate into the clinic because of their toxicity or lack of efficacy. Researchers in the field now face the crucial need to develop effective stroke therapies and successfully translate novel strategies into the clinical setting. Rational Basis for Clinical Translation in Stroke Therapy presents the most recent promising preclinical approaches and the most updated clinical evidence for treating stroke patients. By bringing together the experience of accomplished stroke researchers and clinicians, the book is a useful tool for improving the treatment and management of stroke patients. The book describes current approaches for the management of stroke patients including thrombolysis and mechanical recanalization procedures as well as other clinically relevant topics such as diagnosis, imaging, risk factors, and prevention. Also described are emerging interventions based on the use of stem cells, botulinum toxin, and antidepressants which complement emergency stroke treatment and conventional rehabilitation procedures. Clinical approaches are integrated with the most promising therapeutic opportunities based on targeting the immune system, hypothermia, and postconditioning. The book also covers issues related to the improvement of R&D strategies in stroke therapeutics, aimed at the implementation of preclinical approaches with stroke model guidelines and at the optimization of clinical trial design. This volume is a reference for all those interested in the rational development of novel stroke therapeutics.

Stroke Medicine

Author : Hugh Markus
Publisher : Oxford University Press
ISBN 13 : 0198737882
Total Pages : 609 pages
Book Rating : 4.1/5 (987 download)

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Book Synopsis Stroke Medicine by : Hugh Markus

Download or read book Stroke Medicine written by Hugh Markus and published by Oxford University Press. This book was released on 2017 with total page 609 pages. Available in PDF, EPUB and Kindle. Book excerpt: A practical handbook written for the practising physician, 'Stroke Medicine' provides an up-to-date, and easily accessible source of information on all aspects of stroke care from acute care, through to rehabilitation and secondary prevention.

Genomics and Clinical Medicine

Author : Dhavendra Kumar
Publisher : Oxford University Press
ISBN 13 : 0199720053
Total Pages : 672 pages
Book Rating : 4.1/5 (997 download)

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Book Synopsis Genomics and Clinical Medicine by : Dhavendra Kumar

Download or read book Genomics and Clinical Medicine written by Dhavendra Kumar and published by Oxford University Press. This book was released on 2008-02-15 with total page 672 pages. Available in PDF, EPUB and Kindle. Book excerpt: An important milestone in medicine has been the recent completion of the Human Genome Project. The identification of 30,000 genes and their regulatory proteins provides the framework for understanding the metabolic basis of disease. This advance has also laid the foundation for a broad range of genomic tools that have opened the way for targeted genetic testing in a number of medical disorders. This book is designed to be the first major text to discuss genomics-based advances in disease susceptibility, diagnosis, prognostication,and prediction of treatment outcomes in various areas of medicine. After building a strong underpinning in the basic concepts of genomics, the authors of this book, all leaders in the field, proceed to discuss a wide range of clinical areas and the applications now afforded by genomic analysis.