Stress, the Aging Brain, and the Mechanisms of Neuron Death

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Author :
Publisher : MIT Press (MA)
ISBN 13 :
Total Pages : 454 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Stress, the Aging Brain, and the Mechanisms of Neuron Death by : Robert M. Sapolsky

Download or read book Stress, the Aging Brain, and the Mechanisms of Neuron Death written by Robert M. Sapolsky and published by MIT Press (MA). This book was released on 1992 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt: Looking beyond the now widely recognized relationships between stress and physical illness, this accessible and engagingly written book suggests that stress and stress-related hormones can also endanger the brain.

Science and the Navy

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Publisher : Princeton University Press
ISBN 13 : 140086092X
Total Pages : 159 pages
Book Rating : 4.4/5 (8 download)

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Book Synopsis Science and the Navy by : Harvey M. Sapolsky

Download or read book Science and the Navy written by Harvey M. Sapolsky and published by Princeton University Press. This book was released on 2014-07-14 with total page 159 pages. Available in PDF, EPUB and Kindle. Book excerpt: Addressing all those interested in the history of American science and concerned with its future, a leading scholar of public policy explains how and why the Office of Naval Research became the first federal agency to support a wide range of scientific work in universities. Harvey Sapolsky shows that the ONR functioned as a "surrogate national science foundation" between 1946 and 1950 and argues that its activities emerged not from any particularly enlightened position but largely from a bureaucratic accident. Once involved with basic research, however, the ONR challenged a Navy skeptical of the value of independent scientific advice and established a national security rationale that gave American science its Golden Age. Eventually, the ONR's autonomy was worn away in bureaucratic struggles, but Sapolsky demonstrates that its experience holds lessons for those who are committed to the effective management of science and interested in the ability of scientists to choose the directions for their research. As military support for basic research fades, scientists are discovering that they are unprotected from the vagaries of distributive politics. Originally published in 1990. The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.

Stress and the Aging Brain

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Author :
Publisher :
ISBN 13 : 9780608034348
Total Pages : 239 pages
Book Rating : 4.0/5 (343 download)

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Book Synopsis Stress and the Aging Brain by : Giuseppe Nappi

Download or read book Stress and the Aging Brain written by Giuseppe Nappi and published by . This book was released on 1990-01-01 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Stress and the Aging Brain

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Author :
Publisher : Raven Press (ID)
ISBN 13 :
Total Pages : 248 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Stress and the Aging Brain by : G. Nappi

Download or read book Stress and the Aging Brain written by G. Nappi and published by Raven Press (ID). This book was released on 1990 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Handbook of the Aging Brain

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Author :
Publisher : Elsevier
ISBN 13 : 0080533221
Total Pages : 283 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Handbook of the Aging Brain by : Eugenia Wang

Download or read book Handbook of the Aging Brain written by Eugenia Wang and published by Elsevier. This book was released on 1998-08-13 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of the Aging Brain brings together diverse scientific disciplines to cover the most recent research findings in an easy-to-read summary. Scientists and clinicians will find a wide spectrum of subjects including gerontology, neurology, psychology, molecular biology, and cellular biology. The book includes general chapters on the neuroanatomy and neurobiology of the aging brain, and moves on to discussion of specifics including signal transduction, cell death, and specific cellular and neurological changes associated with dementia, Alzheimer's and Parkinson's Disease. Other chapters discuss the affect of aging on learning and memory, language, and cognition.

The Aging Mind

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Publisher : National Academies Press
ISBN 13 : 0309172195
Total Pages : 285 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Aging Mind by : National Research Council

Download or read book The Aging Mind written by National Research Council and published by National Academies Press. This book was released on 2000-04-18 with total page 285 pages. Available in PDF, EPUB and Kindle. Book excerpt: Possible new breakthroughs in understanding the aging mind that can be used to benefit older people are now emerging from research. This volume identifies the key scientific advances and the opportunities they bring. For example, science has learned that among older adults who do not suffer from Alzheimer's disease or other dementias, cognitive decline may depend less on loss of brain cells than on changes in the health of neurons and neural networks. Research on the processes that maintain neural health shows promise of revealing new ways to promote cognitive functioning in older people. Research is also showing how cognitive functioning depends on the conjunction of biology and culture. The ways older people adapt to changes in their nervous systems, and perhaps the changes themselves, are shaped by past life experiences, present living situations, changing motives, cultural expectations, and emerging technology, as well as by their physical health status and sensory-motor capabilities. Improved understanding of how physical and contextual factors interact can help explain why some cognitive functions are impaired in aging while others are spared and why cognitive capability is impaired in some older adults and spared in others. On the basis of these exciting findings, the report makes specific recommends that the U.S. government support three major new initiatives as the next steps for research.

Brain Aging

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Publisher : CRC Press
ISBN 13 : 1000611558
Total Pages : 335 pages
Book Rating : 4.0/5 (6 download)

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Book Synopsis Brain Aging by : David R. Riddle

Download or read book Brain Aging written by David R. Riddle and published by CRC Press. This book was released on 2007-04-19 with total page 335 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recognition that aging is not the accumulation of disease, but rather comprises fundamental biological processes that are amenable to experimental study, is the basis for the recent growth of experimental biogerontology. As increasingly sophisticated studies provide greater understanding of what occurs in the aging brain and how these changes occur

Handbook of the Neuroscience of Aging

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Publisher : Academic Press
ISBN 13 : 0080954057
Total Pages : 712 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Handbook of the Neuroscience of Aging by : Patrick R. Hof

Download or read book Handbook of the Neuroscience of Aging written by Patrick R. Hof and published by Academic Press. This book was released on 2010-05-22 with total page 712 pages. Available in PDF, EPUB and Kindle. Book excerpt: A single volume of 85 articles, the Handbook of the Neurobiology of Aging is an authoritative selection of relevant chapters from the Encyclopedia of Neuroscience, the most comprehensive source of neuroscience information assembled to date (AP Oct 2008). The study of neural aging is a central topic in neuroscience, neuropsychology and gerontology. Some well-known age-related neurological diseases include Parkinson's and Alzheimer's, but even more common are problems of aging which are not due to disease but to more subtle impairments in neurobiological systems, including impairments in vision, memory loss, muscle weakening, and loss of reproductive functions, changes in body weight, and sleeplessness. As the average age of our society increases, diseases of aging become more common and conditions associated with aging need more attention by doctors and researchers. This book offers an overview of topics related to neurobiological impairments which are related to the aging brain and nervous system. Coverage ranges from animal models to human imaging, fundamentals of age-related neural changes and pathological neurodegeneration, and offers an overview of structural and functional changes at the molecular, systems, and cognitive levels. Key pathologies such as memory disorders, Alzheimer's, dementia, Down syndrome, Parkinson's, and stroke are discussed, as are cutting edge interventions such as cell replacement therapy and deep brain stimulation. There is no other current single-volume reference with such a comprehensive coverage and depth. Authors selected are the internationally renowned experts for the particular topics on which they write, and the volume is richly illustrated with over 100 color figures. A collection of articles reviewing our fundamental knowledge of neural aging, the book provides an essential, affordable reference for scientists in all areas of Neuroscience, Neuropsychology and Gerontology. The most comprehensive source of up-to-date data on the neurobiology of aging, review articles cover: normal, sensory and cognitive aging; neuroendocrine, structural and molecular factors; and fully address both patholgy and intervention Chapters represent an authoritative selection of relevant material from the most comprehensive source of information about neuroscience ever assembled, (Encyclopedia of Neuroscience), synthesizing information otherwise dispersed across a number of journal articles and book chapters, and saving researchers the time consuming process of finding and integrating this information themselves Offering outstanding scholarship, each chapter is written by an expert in the topic area and over 20% of chapters feature international contributors, (representing 11 countries) Provides more fully vetted expert knowledge than any existing work with broad appeal for the US, UK and Europe, accurately crediting the contributions to research in those regions Fully explores various pathologies associated with the aging brain (Alzheimer's, dementia, Parkinson's, memory disorders, stroke, Down's syndrome, etc.) Coverage of disorders and key interventions makes the volume relevant to clinicians as well as researchers Heavily illustrated with over 100 color figures

Neuroglia in the Aging Brain

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1592591051
Total Pages : 513 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Neuroglia in the Aging Brain by : Jean de Vellis

Download or read book Neuroglia in the Aging Brain written by Jean de Vellis and published by Springer Science & Business Media. This book was released on 2001-11-06 with total page 513 pages. Available in PDF, EPUB and Kindle. Book excerpt: A distinguished panel of internationally recognized neuroscientists comprehensively review the involvement of and changes in glial cells both during the normal aging process and in the major disorders of old age. Topics range from the cellular and molecular changes that occur with aging-especially aging-associated activation of astrocytes and microglia and its relation to neuronal injury and repair-to neuron-glia intercommunication. The contributors show how glial signals may be modulated by hormones, growth factors, neurotransmitters, intracellular metabolism, and intercellular exchanges, as well as by aging of the blood-brain barrier.

Development and Aging in the Nervous System

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Publisher : Elsevier
ISBN 13 : 0323159664
Total Pages : 231 pages
Book Rating : 4.3/5 (231 download)

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Book Synopsis Development and Aging in the Nervous System by : Morris Rockstein

Download or read book Development and Aging in the Nervous System written by Morris Rockstein and published by Elsevier. This book was released on 2012-12-02 with total page 231 pages. Available in PDF, EPUB and Kindle. Book excerpt: Development and Aging in the Nervous System covers the proceedings of a series of symposia by the same title, held at the University of Miami Training Program in Cellular Aging on February 19-20, 1973. This book is composed of 11 chapters that specifically consider aging in its total sense, from embryonic development through senescence of a vital organ system of the body. The introductory chapters review the age changes in the neuronal microenvironment and the regulative mechanism of neuronal death in cell number control in the nervous system. The next chapters deal with the neuronal degeneration in aging mammals, the selected changes in the developing postnatal rat, and the trophic influences in the mammalian central nervous system. These topics are followed by discussions of the genesis of neuronal locus specificity, the vertebrate brain aging, and the neurochemical patterns in the developing and aging brain. The remaining chapters describe the mechanisms of enzymatic differentiation in the brain and in cultured cells and the monoamine metabolism in the aging male mouse. This book will prove useful to development and cell biologists, researchers, and advance students.

The Aging Brain

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Publisher :
ISBN 13 :
Total Pages : 182 pages
Book Rating : 4.:/5 (12 download)

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Book Synopsis The Aging Brain by : Lawrence J. Whalley

Download or read book The Aging Brain written by Lawrence J. Whalley and published by . This book was released on 2001 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt: Why do some people remain alert and vigorous at an age when others are declining mentally and physically? Does their apparent advantage have a biological basis, and, if so, could this success be transferred to others predisposed to age more quickly? If this is achievable, does brain aging then become the last obstacle to an extension of our useful life span? These are just some of the questions answered in this book by Lawrence Whalley, a researcher who specializes in the study of Alzheimer©s disease. He relates that the brain may be able to compensate for its own aging since the loss of brain cells with age is not as extensive as once believed and that, if some surviving cells retain the capacity to replicate, there may be real prospects of reducing the worst effects of brain aging. In surveying the prospects of slowing or even preventing the worst effects of aging, Whalley looks at the development of the brain and how this is influenced by environmental factors such as diet and stress, the biological and psychological mechanisms of brain injury and disease, and the range of possible treatments and preventative measures, including gene therapy, silicon-neuron implants, virtual reality, and "intelligent environments." Throughout the book he relates the known facts about brain aging, as well as our many preconceptions. Reexamining older scientific studies, the author is able to show that though much of what we take for granted about the mental processes of the older person is not simple, we may indeed be able to alleviate the effects of mental deterioration--if not now, then in the future.

Neural Plasticity and Memory

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Publisher : CRC Press
ISBN 13 : 1420008412
Total Pages : 368 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Neural Plasticity and Memory by : Federico Bermudez-Rattoni

Download or read book Neural Plasticity and Memory written by Federico Bermudez-Rattoni and published by CRC Press. This book was released on 2007-04-17 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive, multidisciplinary review, Neural Plasticity and Memory: From Genes to Brain Imaging provides an in-depth, up-to-date analysis of the study of the neurobiology of memory. Leading specialists share their scientific experience in the field, covering a wide range of topics where molecular, genetic, behavioral, and brain imaging techniq

Translational Research in Traumatic Brain Injury

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Publisher : CRC Press
ISBN 13 : 1498766579
Total Pages : 388 pages
Book Rating : 4.4/5 (987 download)

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Book Synopsis Translational Research in Traumatic Brain Injury by : Daniel Laskowitz

Download or read book Translational Research in Traumatic Brain Injury written by Daniel Laskowitz and published by CRC Press. This book was released on 2016-04-21 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the developme

The Aging Brain

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Author :
Publisher : Raven Press (ID)
ISBN 13 :
Total Pages : 312 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Aging Brain by : Ezio Giacobini

Download or read book The Aging Brain written by Ezio Giacobini and published by Raven Press (ID). This book was released on 1982 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Does Stress Damage the Brain?

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Author :
Publisher : W. W. Norton & Company
ISBN 13 : 9780393703450
Total Pages : 342 pages
Book Rating : 4.7/5 (34 download)

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Book Synopsis Does Stress Damage the Brain? by : J. Douglas Bremner

Download or read book Does Stress Damage the Brain? written by J. Douglas Bremner and published by W. W. Norton & Company. This book was released on 2002 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: Everyone who has ever experienced stress, or wondered about the effects of stress on their minds and bodies, will benefit from the insights in this clearly written and accessible book.

Handbook of the Psychology of Aging

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Publisher : Academic Press
ISBN 13 : 0123808839
Total Pages : 436 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis Handbook of the Psychology of Aging by : K Warner Schaie

Download or read book Handbook of the Psychology of Aging written by K Warner Schaie and published by Academic Press. This book was released on 2010-12-21 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Handbook of the Psychology of Aging, Seventh Edition, provides a basic reference source on the behavioral processes of aging for researchers, graduate students, and professionals. It also provides perspectives on the behavioral science of aging for researchers and professionals from other disciplines. The book is organized into four parts. Part 1 reviews key methodological and analytical issues in aging research. It examines some of the major historical influences that might provide explanatory mechanisms for a better understanding of cohort and period differences in psychological aging processes. Part 2 includes chapters that discuss the basics and nuances of executive function; the history of the morphometric research on normal brain aging; and the neural changes that occur in the brain with aging. Part 3 deals with the social and health aspects of aging. It covers the beliefs that individuals have about how much they can control various outcomes in their life; the impact of stress on health and aging; and the interrelationships between health disparities, social class, and aging. Part 4 discusses the emotional aspects of aging; family caregiving; and mental disorders and legal capacities in older adults. Contains all the main areas of psychological gerontological research in one volume Entire section on neuroscience and aging Begins with a section on theory and methods Edited by one of the father of gerontology (Schaie) and contributors represent top scholars in gerontology

The Aging Brain

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Author :
Publisher :
ISBN 13 :
Total Pages : 376 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Aging Brain by : Paola S. Timiras

Download or read book The Aging Brain written by Paola S. Timiras and published by . This book was released on 1998-01-16 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: The brain is the most complex organ system in the human, both in the intricacy of its cellular architecture and in the extent of its repertoire of macromolecules. The Aging Brain presents the current state of understanding of molecular, cellular, and functional changes that occur in normal brain aging, and compares and contrasts those changes with events occurring in age-related neurodegenerative disorders. The chapters, written by world leaders in the field of brain aging, provide a timely and comprehensive consideration of key areas of this rapidly growing field of aging research. The topics covered include structural, functional, biochemical and molecular changes that occur during usual aging and in age-related neurological disorders. An emphasis is placed on emerging findings at the cellular and molecular levels. The roles of oxidative stress and perturbed energy metabolism in aging and neurodegenrative disorders are covered in considerable detail. In addition, the impact of aging and disease on specific neurotransmitter, neurotrophic factor and cytokine signaling pathways is reviewed. Finally, recent findings concerning possible approaches to reduce risk for age-related neurodegenerative disorders, such as caloric restriction, are presented. The collective body of information presented in The Aging Brain will provide those stepping into the field of brain aging with an overview of our current understanding of fundamental changes that occur in the aging brain, and their molecular and cellular underpinnings. At the same time, the book delves deeply into critical mechanistic details of brain aging that should prove valuable to experts in the field.