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Stimulus Secretion Coupling In The Human Neutrophil
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Book Synopsis The Neutrophil: Cellular Biochemistry and Physiology by : Maurice B. Hallett
Download or read book The Neutrophil: Cellular Biochemistry and Physiology written by Maurice B. Hallett and published by CRC Press. This book was released on 2018-01-18 with total page 261 pages. Available in PDF, EPUB and Kindle. Book excerpt: A synthesis and collation of the recent material regarding the role of the neutrophil in basic pathological processes is presented in this volume. The mechanisms of chemotaxis, secretion, phagocytosis, intracellular killing, oxygen radical production and arachidonate production are comprehensively reviewed. Stimulus response coupling in the neutrophil, with chapters on intracellular Ca2+, C-Kinase, phospholipid metabolism, microfilaments and membrane electrophysiology are extensively discussed. Each chapter provides a critical review by experts with over 1,000 cited references. Invaluable to graduate students and medical and scientific researchers, this book provides a unique, up-to-date account of cellular biochemistry and physiology of the neutrophil.
Book Synopsis The Neutrophil by : Maurice B. Hallett
Download or read book The Neutrophil written by Maurice B. Hallett and published by CRC Press. This book was released on 1989-01-31 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: A synthesis and collation of the recent material regarding the role of the neutrophil in basic pathological processes is presented in this volume. The mechanisms of chemotaxis, secretion, phagocytosis, intracellular killing, oxygen radical production and arachidonate production are comprehensively reviewed. Stimulus response coupling in the neutrophil, with chapters on intracellular Ca2+, C-Kinase, phospholipid metabolism, microfilaments and membrane electrophysiology are extensively discussed. Each chapter provides a critical review by experts with over 1,000 cited references. Invaluable to graduate students and medical and scientific researchers, this book provides a unique, up-to-date account of cellular biochemistry and physiology of the neutrophil.
Book Synopsis Regulation of Leukocyte Function by : Ralph Snyderman
Download or read book Regulation of Leukocyte Function written by Ralph Snyderman and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 423 pages. Available in PDF, EPUB and Kindle. Book excerpt: There was a time, not all that long ago, when scientific study of the cell was called cytology, and the workers in the field named themselves cytologists. When I was a medical student, lectures in cytology were a special, segregated part of the curriculum in the histology course, given along with general anatomy, and they were, as I recall, the surest of cures for insomnia. I still possess Cowdry's three-volume set entitled Special Cytology, published in 1934, and leafing through these books today is rather like examining a medieval manuscript. You could never have guessed what was going to happen to the field. At that time it was all structure, and all guesswork about the structure. When cells were packed together in various tissues, how did the geometry of packing work? How many sides did a liver cell have, in real life? What on earth were all those granules in side, and what were the best stains for looking at them? One thing about those granules, they never moved. Indeed, nothing moved. Cytology turned into cell biology much later on, and suddenly came alive. As has been the case in so many diSciplines in biology, it was brought to life by techniques. New instruments and cytochemical methods were devised for look ing at cells, manipulating cells, more or less in vivo.
Book Synopsis Energetics of Secretion Responses by : J.W.N. Akkerman
Download or read book Energetics of Secretion Responses written by J.W.N. Akkerman and published by CRC Press. This book was released on 2019-01-15 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides a multidisciplinary approach to the study of energetics of secretion responses by combining the knowledge and expertise of leading authorities from various fields.
Download or read book Membrane Fusion written by Jan Wilschut and published by CRC Press. This book was released on 2019-11-14 with total page 927 pages. Available in PDF, EPUB and Kindle. Book excerpt: This balanced volume provides a broad and coherent overview of recent progress in membrane fusion research—highlighting an interdisciplinary treatment of the subject from the fields of biophysics, biochemistry, cell biology, virology, and biotechnology—in a single volume., Featuring easy-access sections on the general properties of membranes and applications of membrane fusion techniques, this valuable sourcebook outlines membrane structure, lipid polymorphism, and intermembrane forces ... covers membrane fusion in model systems ... presents the fusogenic properties of enveloped viruses ... discusses the fusion and flow of intracellular membranes and cell-cell fusion occurring during fertilization and myogenesis ... offers applications of membrane fusion techniques in cell-biological research and biotechnology ... and more. Supplying a comprehensive view of this exciting topic, Membrane Fusion is a working resource for molecular, cell, and membrane biologists; biophysicists; biochemists; virologists; biotechnologists; microbiologists; immunologists; physiologists; and graduate and medical school students in biophysics, biochemistry, physiology, virology, cell biology, and biotechnology.
Book Synopsis Eukaryotic Cell Cultures by : Ronald T. Acton
Download or read book Eukaryotic Cell Cultures written by Ronald T. Acton and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 551 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Second International Cell Culture Congress was structured as was the First Congress to bring together scientists from academia and industry to discuss the use of cell culture in support of bioscience. It was felt that a forum whereby state-of the-art presentations were followed by informal workshops would provide opportunity for the greatest exchange of information. Within the atmosphere of the workshop, problems common to basic as well as applied research were discussed and directions for the future were brought to light. These proceedings reflect and epitomize those discussions. Although it is difficult to cover all scientific disciplines utilizing cells in culture, we feel key areas were addressed at the Congress and are herein presented. Considerable emphasis has been given to the methods for establishing cells in culture and characterizing the cells once established as well as the improved technology for growing established cell lines. Examples of how recombinant DNA technology is being used to manipulate genes within mammalian cells, to clone mammalian genes and to insert them in prokaryotes has been included. Major emphasis has been given to the use of lymphocytes in culture for understanding immune responsiveness and the culturing of a variety of cell types as a means to understand disease states.
Download or read book Immunoregulation written by Nicola Fabris and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 473 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immunoregulation is one of the areas which has witnessed the most explosive advances of immunology during the past decade. It is in this area that the current view of the immune system has arisen and developed. There is indeed little doubt that immune reactions are primarily determined by messages which are genera ted within the immune system and passed among different types of immunologie cells. This cell communication not only determines the type, intensity and duration of the response after perturbation of the immune system by exogenous antigens, but it is also essential for preventing autoimmune reactions and their clinical conse quences. In order to assure aperfect balance within the enormous com plexity of the immune system, it is not surprising that multiple self-regulatory mechanisms are organized at different levels, such as antibody feedback, idiotypic-anti-idiotypic responses, suppres sor and helper T cells, lymphokine signals and genetic require ments. A nu mb er of observations in recent years have, however, demonstrated that consistent contributions to the immunological homeostasis are given also by signals generated outside of the immune system, namely,in the central and autonomous nervous system as weIl as in the endocrine apparatus. Furthermore, the interactions between the immune system and the other body homestatic mechanisms seem to be bidirectional: if immunological cells may be targets of neuroendocrinological factors, immunological products seem in turn to contribute to the neuro endocrine homeostasis.
Book Synopsis Current Topics in Membranes and Transport by :
Download or read book Current Topics in Membranes and Transport written by and published by Academic Press. This book was released on 1990-05-23 with total page 647 pages. Available in PDF, EPUB and Kindle. Book excerpt: Current Topics in Membranes and Transport
Download or read book Cumulated Index Medicus written by and published by . This book was released on 1989 with total page 1422 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Pharmacology of the Skin I written by and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 527 pages. Available in PDF, EPUB and Kindle. Book excerpt: The recent interest in the pharmacology of the skin and the treatment of its diseases has come about for two reasons. The first is a realisation that many aspects of pharmacology can be studied as easily in human skin, where they may be more relevant to human physiology and diseases, as in animal models. Examples of this are the action of various vasoactive agents and the isolation of mediators of inflammation after UV irradiation and antigen-induced dermatitis. The second reason is the fortuitous realisation that a pharmacological approach to the treatment of skin disease need not always await the full elucidation of etiology and mechanism. For example, whilst the argument continued unresolved as to whether the pilo-sebaceous infection which constitutes acne was due to a blocked duct or to a simple increase in sebum production, 13-cis-retinoic acid was found quite by chance totally to ablate the disease; again, whilst cyclosporin, fresh from its triumphs in organ transplantation, has been found able to suppress the rash of psoriasis, it has resuscitated the debate on etiology. We are therefore entering a new era in which the pharmacology and clinical pharmacology of skin are being studied as a fascinating new way of exploring questions of human physiology and pharmacology as well as an important step in the development and study of new drugs, use of which will improve disease control and at the same time help to define pathological mechanisms.
Download or read book Na+H+ Exchange written by S. Grinstein and published by CRC Press. This book was released on 2018-05-04 with total page 373 pages. Available in PDF, EPUB and Kindle. Book excerpt: Prepared by leading scientists in the field, these volumes compile for the first time, concise, up-to-date reviews of several aspects of the basic properties, distribution, function and regulation of the Na+/H+ antiport. In addition, current methods and the use of inhibitors and ligands for the study of the exchanger are described. These volumes are indispendable to researchers and students in the areas of ion transport, membrane biology and cellular physiology.
Book Synopsis Calcium and Cellular Secretion by : Ronald P. Rubin
Download or read book Calcium and Cellular Secretion written by Ronald P. Rubin and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the publication of my previous monograph in 1974, important progress has been made in the broad area of calcium research, partic ularly as it pertains to secretory phenomena. The significant advance in methodology, while widening the scope of our knowledge, has caused research in this particular area to become more and more specialized. It has, therefore, become increasingly difficult for researchers to consider and evaluate work outside their own areas of specialization and to com prehend the field from a broad perspective. While many valuable re views on the importance of calcium in cellular function are being pro duced, they have not attempted to pull together all of the existing knowledge into a more general narrative. This volume brings together experimental data and theories from diverse sources, and attempts to synthesize into a broad conceptual framework the massive amount of specialized information that presently exists in the general area of cal cium metabolism and the secretory process. It is impossible in a book of this length to discuss specific references in detail and still maintain readability, so generalizations must be made.
Book Synopsis Mast Cells, Mediators and Disease by : Stephen T. Holgate
Download or read book Mast Cells, Mediators and Disease written by Stephen T. Holgate and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 293 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1879 Paul Ehrlich first described the mast cell as a tissue fixed cell contain ing many granules which, when stained with basic dyes, such as toluidine blue, changed the colour spectrum of the dye in a process called meta chromasia. Since this early description, pathologists, physicians and pharmacologists have been fascinated by this cell on account of its central involvement in human allergic diseases. Approximately four decades after Ehrlich's first description of the mast cell, Prausnitz and Kiistner reported their pioneer experiment, demonstrating that the immediate skin wheal response to allergen could be passively transferred with serum. They named the antigen-specific serum factor reagin. A further four and one half decades had to pass before the connection between the mast cell and reagin could be made with the identification of reagin as an immunoglobulin E by Johansson and Ishizaka and its unique property to bind with high affinity to specific receptors on mast cells and basophils. Meanwhile in the 1920s Coca published a series of papers in which he described the clinical features of acute allergic responses and first used the term atopy. This, together with the fundamental pharmacological studies of Sir Henry Dale in identifying histamine as one mediator of the acute ana phylactic reaction, provided the second approach which eventually linked the mast cell to allergic tissue reactions. Indeed, it was Best, working in Dale's group who first showed that histamine was a chemical stored in mast cells.
Book Synopsis Contemporary Topics in Immunobiology by : Ralph Snyderman
Download or read book Contemporary Topics in Immunobiology written by Ralph Snyderman and published by . This book was released on 1972 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Immunopharmacology and Inflammation by : Carlo Riccardi
Download or read book Immunopharmacology and Inflammation written by Carlo Riccardi and published by Springer. This book was released on 2018-06-09 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive overview of the current research on inflammation and immunopharmacology, with particular attention to the use of anti-inflammatory drugs, this book discusses future trends in this area of pharmacological research. It addresses an audience with basic knowledge in the inflammatory process, immune system and pharmacology. The book meets the needs of graduate students, junior and senior researchers and is useful as a source of the most current information for those already working in these fields.
Book Synopsis Calcium in Biological Systems by : Ronald P. Rubin
Download or read book Calcium in Biological Systems written by Ronald P. Rubin and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 697 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is based in part upon the proceedings of the Calcium Theme held during the 67th Annual Meeting of the Federation of American Societies for Experimental Biology, which took place in Chicago, AprillO-lS, 1983. The American Society for Pharmacology and Experimental Therapeutics had the primary responsibility for organizing the scientific program with the assistance of other member societies, including the American Physiology Society, American Association of Pathologists, and American Institute of Nutrition. The purpose of the Calcium Theme was to review progress in the diverse areas of investigation bearing on the ubiquitous role of calcium in biological systems. In addition to contributions from those participating in the Theme, this volume also includes a number of invited papers that were added to fill certain voids in topics covered. The authors were selected because they are investigators active in the mainstream of their particular research area, possessing the acumen to analyze cogently not only their own recent findings but also to relate these findings to their respective area. New information as well as reviews of current concepts generally highlight the individual contributions. Undoubtedly, some readers may argue with the emphasis made and/or the conclusions reached on individual topics. In such cases, other volumes will hopefully provide a forum for alternative points of view. Due to the broad scope of subjects covered and the large number of contributions, the papers have been arranged in three sections.
Download or read book Research Awards Index written by and published by . This book was released on 1989 with total page 776 pages. Available in PDF, EPUB and Kindle. Book excerpt: