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Sticky Blood Explained
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Book Synopsis Sticky Blood Explained by : Kay Thackray
Download or read book Sticky Blood Explained written by Kay Thackray and published by Braiswick at By Design. This book was released on 2002 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt: The description by Graham Hughes of the ?antiphospholipid syndrome? or Hughes Syndrome is one of the medical landmarks of the 20th century.There is something of a fashion in science to play down ?clinical? discoveries as being somehow less ground-breaking than ?basic? laboratory based observations.Here is a disease, a medical discovery, which should turn such fashions around. In a series of brilliant clinical observations, Dr Hughes, not only pieced together what is now clearly a common and important disease, but also, with his team, set up the blood tests and treatment guidelines, which are used world-wide.Kay Thackray describes the condition as a patient, providing a clear practical guide to living life.
Book Synopsis The Antiphospholipid Syndrome by : Ronald A. Asherson
Download or read book The Antiphospholipid Syndrome written by Ronald A. Asherson and published by CRC Press. This book was released on 2018-05-04 with total page 357 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by the foremost researchers in the field, this book gathers together in a single source the many important clinical associations of antiphospholipid antibodies. Antibody-related clotting mechanisms and their relationship to conditions such as recurrent strokes, chorea, multi infarct dementias, a variety of spinal syndromes, Addison's Disease, recurrent miscarriages, and many more are discussed in depth. The importance of these antibodies in 'Primary,' 'Secondary,' and 'Catastrophic' Antiphospholipid Syndrome is highlighted. Each chapter is devoted to a specific internal system and the clinical effects this syndrome has on that system. This authoritative book is an essential addition to medical libraries as well as an invaluable reference for general physicians, internists, rheumatologists, neurologists, cardiologists, nephrologists, endocrinologists, gastroenterologists, pulmonologists, dermatologists, and obstetricians.
Book Synopsis Sticky Blood Explained: Hughes Syndrome by : Kay Thackray
Download or read book Sticky Blood Explained: Hughes Syndrome written by Kay Thackray and published by Arima Publishing. This book was released on 2018-09-05 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hughes Syndrome is now recognised as a major 'new' disease. It has been described by colleague Dr Josep Font of Barcelona, as, "one of the two new diseases (with AIDS) of the 20th century." The messages are simple. Blood clots can cause untold damage. The tendency to 'sticky blood' found in Hughes Syndrome can be diagnosed by simple blood tests. The use of medicines, some as simple as aspirin, can protect against the clotting tendency. Kay Thackray here provides just the sort of clear guidance patients with Hughes Syndrome need. Coming from a patient, and coming straight from the heart, I believe that the lessons provided by this book are beyond value. - Munther A Khamashta MD FRCP Consultant Physician, Lupus Unit ST THOMAS' HOSPITAL, LONDON
Book Synopsis Inflammation and the Microcirculation by : D. Neil Granger
Download or read book Inflammation and the Microcirculation written by D. Neil Granger and published by Morgan & Claypool Publishers. This book was released on 2010 with total page 99 pages. Available in PDF, EPUB and Kindle. Book excerpt: The microcirculation is highly responsive to, and a vital participant in, the inflammatory response. All segments of the microvasculature (arterioles, capillaries, and venules) exhibit characteristic phenotypic changes during inflammation that appear to be directed toward enhancing the delivery of inflammatory cells to the injured/infected tissue, isolating the region from healthy tissue and the systemic circulation, and setting the stage for tissue repair and regeneration. The best characterized responses of the microcirculation to inflammation include impaired vasomotor function, reduced capillary perfusion, adhesion of leukocytes and platelets, activation of the coagulation cascade, and enhanced thrombosis, increased vascular permeability, and an increase in the rate of proliferation of blood and lymphatic vessels. A variety of cells that normally circulate in blood (leukocytes, platelets) or reside within the vessel wall (endothelial cells, pericytes) or in the perivascular space (mast cells, macrophages) are activated in response to inflammation. The activation products and chemical mediators released from these cells act through different well-characterized signaling pathways to induce the phenotypic changes in microvessel function that accompany inflammation. Drugs that target a specific microvascular response to inflammation, such as leukocyte-endothelial cell adhesion or angiogenesis, have shown promise in both the preclinical and clinical studies of inflammatory disease. Future research efforts in this area will likely identify new avenues for therapeutic intervention in inflammation. Table of Contents: Introduction / Historical Perspectives / Anatomical Considerations / Impaired Vasomotor Responses / Capillary Perfusion / Angiogenesis / Leukocyte-Endothelial Cell Adhesion / Platelet-Vessel Wall Interactions / Coagulation and Thrombosis / Endothelial Barrier Dysfunction / Epilogue / References
Download or read book The Endothelium written by Michel Félétou and published by Morgan & Claypool Publishers. This book was released on 2011 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: The endothelium, a monolayer of endothelial cells, constitutes the inner cellular lining of the blood vessels (arteries, veins and capillaries) and the lymphatic system, and therefore is in direct contact with the blood/lymph and the circulating cells. The endothelium is a major player in the control of blood fluidity, platelet aggregation and vascular tone, a major actor in the regulation of immunology, inflammation and angiogenesis, and an important metabolizing and an endocrine organ. Endothelial cells controls vascular tone, and thereby blood flow, by synthesizing and releasing relaxing and contracting factors such as nitric oxide, metabolites of arachidonic acid via the cyclooxygenases, lipoxygenases and cytochrome P450 pathways, various peptides (endothelin, urotensin, CNP, adrenomedullin, etc.), adenosine, purines, reactive oxygen species and so on. Additionally, endothelial ectoenzymes are required steps in the generation of vasoactive hormones such as angiotensin II. An endothelial dysfunction linked to an imbalance in the synthesis and/or the release of these various endothelial factors may explain the initiation of cardiovascular pathologies (from hypertension to atherosclerosis) or their development and perpetuation. Table of Contents: Introduction / Multiple Functions of the Endothelial Cells / Calcium Signaling in Vascular Cells and Cell-to-Cell Communications / Endothelium-Dependent Regulation of Vascular Tone / Conclusion / References
Author :United States. Public Health Service. Office of the Surgeon General Publisher : ISBN 13 : Total Pages :728 pages Book Rating :4.:/5 (318 download)
Book Synopsis How Tobacco Smoke Causes Disease by : United States. Public Health Service. Office of the Surgeon General
Download or read book How Tobacco Smoke Causes Disease written by United States. Public Health Service. Office of the Surgeon General and published by . This book was released on 2010 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
Book Synopsis Cancer-Associated Thrombosis by : Alok A. Khorana
Download or read book Cancer-Associated Thrombosis written by Alok A. Khorana and published by CRC Press. This book was released on 2007-09-26 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: Showcasing the expertise of top-tier specialists who contributed to the newly released guidelines for the care of thrombosis in cancer patients, this exciting guide was written and edited by members of the American Society of Clinical Oncology panel, (ASCO), on the prevention and treatment of cancer-associated thrombosis, among others, and provides
Download or read book Blood Politics written by Circe Sturm and published by Univ of California Press. This book was released on 2002-03-20 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Blood Politics offers an anthropological analysis of contemporary identity politics within the second largest Indian tribe in the United States--one that pays particular attention to the symbol of "blood." The work treats an extremely sensitive topic with originality and insight. It is also notable for bringing contemporary theories of race, nationalism, and social identity to bear upon the case of the Oklahoma Cherokee."—Pauline Turner Strong, author of Captive Selves, Captivating Others: The Politics and Poetics of Colonial American Captivity Narratives
Book Synopsis Understanding Hughes Syndrome by : Graham Hughes
Download or read book Understanding Hughes Syndrome written by Graham Hughes and published by Springer Science & Business Media. This book was released on 2010-01-23 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt: Along with AIDS, antiphospholipid syndrome was the major medical discovery of the late 20th century, so for many it is still deemed a ‘new’ disease. The discovery of ‘sticky blood’ (commonly known as antiphospholipid syndrome or ‘Hughes Syndrome’) came out of years of observation of patients who had developed lupus. Many specialists in the 1970s were interested in the neurological aspects of lupus, and Dr Hughes, among others, spent a number of years studying the mechanisms of brain inflammation. In the mid 1970s, Hughes observed a number of young women with a form of viral paralysis, where interestingly many of them carried an antibody in their blood actually directed against ‘phospholipid’ – one of the components of brain and spinal cord. It quickly became apparent that individuals who had "anti-phospholipid antibodies" suffered from a tendency not only to develop brain and spinal cord symptoms, but also a tendency to develop both vein and artery thrombosis. As investigation continued it became apparent that these symptoms were not just confined to lupus patients, but occurred in others too, specifically those with severe migraines, with repeated strokes, with memory loss, and in women with recurrent miscarriage.
Book Synopsis Anatomy and Physiology by : J. Gordon Betts
Download or read book Anatomy and Physiology written by J. Gordon Betts and published by . This book was released on 2013-04-25 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Paradise Rot written by Jenny Hval and published by Verso Books. This book was released on 2018-10-02 with total page 119 pages. Available in PDF, EPUB and Kindle. Book excerpt: Jo is in a strange new country for university and having a more peculiar time than most. In a house with no walls, shared with a woman who has no boundaries, she finds her strange home coming to life in unimaginable ways. Jo's sensitivity and all her senses become increasingly heightened and fraught, as the lines between bodies and plants, dreaming and wakefulness, blur and mesh. This debut novel from critically acclaimed artist and musician Jenny Hval presents a heady and hyper-sensual portrayal of sexual awakening and queer desire.
Download or read book Hematology written by Ronald Hoffman and published by . This book was released on 2005 with total page 2821 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Autoimmune Epidemic by : Donna Jackson Nakazawa
Download or read book The Autoimmune Epidemic written by Donna Jackson Nakazawa and published by Simon and Schuster. This book was released on 2009-02-10 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: From the Foreword: [An] astounding book . . . put simply, there is no doubt that autoimmune diseases are on the rise and increasing environmental exposures of toxins and chemicals is fueling this rise.--Dr. Douglas Kerr, Director, Johns Hopkins Transverse Myelitis Center.
Download or read book In Cold Blood written by Truman Capote and published by Modern Library. This book was released on 2013-02-19 with total page 417 pages. Available in PDF, EPUB and Kindle. Book excerpt: Selected by the Modern Library as one of the 100 best nonfiction books of all time From the Modern Library’s new set of beautifully repackaged hardcover classics by Truman Capote—also available are Breakfast at Tiffany’s and Other Voices, Other Rooms (in one volume), Portraits and Observations, and The Complete Stories Truman Capote’s masterpiece, In Cold Blood, created a sensation when it was first published, serially, in The New Yorker in 1965. The intensively researched, atmospheric narrative of the lives of the Clutter family of Holcomb, Kansas, and of the two men, Richard Eugene Hickock and Perry Edward Smith, who brutally killed them on the night of November 15, 1959, is the seminal work of the “new journalism.” Perry Smith is one of the great dark characters of American literature, full of contradictory emotions. “I thought he was a very nice gentleman,” he says of Herb Clutter. “Soft-spoken. I thought so right up to the moment I cut his throat.” Told in chapters that alternate between the Clutter household and the approach of Smith and Hickock in their black Chevrolet, then between the investigation of the case and the killers’ flight, Capote’s account is so detailed that the reader comes to feel almost like a participant in the events.
Book Synopsis The Antiphospholipid Syndrome II by : Ronald A. Asherson
Download or read book The Antiphospholipid Syndrome II written by Ronald A. Asherson and published by Gulf Professional Publishing. This book was released on 2002-08-22 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the reader with a comprehensive overview of the Antiphospholipid syndrome. One of the most important advances in rheumatology and connective tissue diseases of the last decade. It provides an explanation for many previously undefined conditions with no clear pathogenesis encompassing all subspeculations in internal medicine as well as obstetrics. Clotting problems leading to strokes and myocardial infarctions (in younger people) as well as a large variety of other syndromes such as chorea, hyproadrenalism, pulmonary problems are now being understood.
Book Synopsis Better the Blood by : Michael Bennett
Download or read book Better the Blood written by Michael Bennett and published by Grove Press. This book was released on 2023-01-10 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: An absorbing, clever debut thriller that speaks to the longstanding injustices faced by New Zealand’s indigenous peoples, by an acclaimed Māori screenwriter and director A tenacious Māori detective, Hana Westerman juggles single motherhood, endemic prejudice, and the pressures of her career in Auckland CIB. Led to a crime scene by a mysterious video, she discovers a man ritualistically hanging in a secret room and a puzzling inward-curving inscription. Delving into the investigation after a second, apparently unrelated, death, she uncovers a chilling connection to an historic crime: 160 years before, during the brutal and bloody British colonization of New Zealand, a troop of colonial soldiers unjustly executed a Māori Chief. Hana realizes that the murders are utu—the Māori tradition of rebalancing for the crime committed eight generations ago. There were six soldiers in the British troop, and since descendants of two of the soldiers have been killed, four more potential murders remain. Hana is thus hunting New Zealand’s first serial killer. The pursuit soon becomes frighteningly personal, recalling the painful event, two decades before, when Hana, then a new cop, was part of a police team sent to end by force a land rights occupation by indigenous peoples on the same ancestral mountain where the Chief was killed, calling once more into question her loyalty to her roots. Worse still, a genealogical link to the British soldiers brings the case terrifyingly close to Hana’s own family. Twisty and thought-provoking, Better the Blood is the debut of a remarkable new talent in crime fiction.
Download or read book Hughes Syndrome written by Graham Hughes and published by Springer Science & Business Media. This book was released on 2001-04-02 with total page 76 pages. Available in PDF, EPUB and Kindle. Book excerpt: As with any delicate machine, the human body can be profoundly affected by its supply of vital running materials. Thus, the tendency for the blood to clot excessively has the potential to cut off the oxygen supply to any organ of the body. In 1983, Dr Graham Hughes and his team in London described a syndrome and subsequently developed simple blood tests to diagnose the condition. This syndrome is characterised by thrombosis (both in limbs and internal organs), headaches, memory loss, strokes and, in pregnant women, placental clotting and recurrent miscarriage. The syndrome, now known worldwide as Hughes Syndrome, or the anti-phospholipid syndrome, is common - being responsible for example, for up to 1 in 5 cases of young stroke. More important, it is treatable. This book provides the first in-depth description of the syndrome for patients.
