Steroid Protein Interactions Ii

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Steroid-protein Interactions

Author : Ulrich Westphal
Publisher : Springer
ISBN 13 :
Total Pages : 592 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Steroid-protein Interactions by : Ulrich Westphal

Download or read book Steroid-protein Interactions written by Ulrich Westphal and published by Springer. This book was released on 1971 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the story of steroid-protein interactions as one investigator sees it. Following the general concept of this monograph series, it emphasizes the results and interpretations obtained in the author's laboratory, and is therefore a subjective account. Recognizing, how ever, that the discussion of the subject would be incomplete if the material were limited to one scientist's work, the essential achieve ments of other investigators have been incorporated. An effort has thus been made to give a balanced presentation and to enable the reader to see in perspective the varied facets of the interactions between steroids and proteins. Since this is the first comprehensive treatment of the topic, it seems appropriate to go to the roots, and try to find out how it all started. The first chapters, therefore, take the reader to the laboratories of those who very early conceived the significance of the attachment of dyes, drugs, and other conspicuous molecules to those colloids called proteins. The discovery of the steroid hormones set the stage for meaningful investigation of their interaction with proteins of various origins and functions - a process which is continuing today with increasing vigor.

Steroid-Protein Interactions II

Author : Ulrich Westphal
Publisher : Springer Science & Business Media
ISBN 13 : 3642824862
Total Pages : 620 pages
Book Rating : 4.6/5 (428 download)

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Book Synopsis Steroid-Protein Interactions II by : Ulrich Westphal

Download or read book Steroid-Protein Interactions II written by Ulrich Westphal and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 620 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Steroid-Protein Interactions

Author : Ulrich Westphal
Publisher : Springer Science & Business Media
ISBN 13 : 3642462626
Total Pages : 578 pages
Book Rating : 4.6/5 (424 download)

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Book Synopsis Steroid-Protein Interactions by : Ulrich Westphal

Download or read book Steroid-Protein Interactions written by Ulrich Westphal and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 578 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the story of steroid-protein interactions as one investigator sees it. Following the general concept of this monograph series, it emphasizes the results and interpretations obtained in the author's laboratory, and is therefore a subjective account. Recognizing, how ever, that the discussion of the subject would be incomplete if the material were limited to one scientist's work, the essential achieve ments of other investigators have been incorporated. An effort has thus been made to give a balanced presentation and to enable the reader to see in perspective the varied facets of the interactions between steroids and proteins. Since this is the first comprehensive treatment of the topic, it seems appropriate to go to the roots, and try to find out how it all started. The first chapters, therefore, take the reader to the laboratories of those who very early conceived the significance of the attachment of dyes, drugs, and other conspicuous molecules to those colloids called proteins. The discovery of the steroid hormones set the stage for meaningful investigation of their interaction with proteins of various origins and functions - a process which is continuing today with increasing vigor.

Diagnosis and Management of Ovarian Disorders

Author : Albert Altchek
Publisher : Elsevier
ISBN 13 : 008049451X
Total Pages : 595 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Diagnosis and Management of Ovarian Disorders by : Albert Altchek

Download or read book Diagnosis and Management of Ovarian Disorders written by Albert Altchek and published by Elsevier. This book was released on 2003-09-04 with total page 595 pages. Available in PDF, EPUB and Kindle. Book excerpt: This updated second edition of Diagnosis and Management of Ovarian Disorders provides thorough, yet succinct insight into the ever-changing realm of ovarian disorders. It presents a novel multidisciplinary approach to the subject as described by clinicians, surgeons, pathologists, basic scientists and related medical researchers. Topics covered include reproductive technology, early diagnosis of ovarian cancer, and management of menopause among others. The breadth of information provided by this book will appeal to clinicians and researchers involved in the study and treatment of ovarian disorders.KEY FEATURES* Includes updated information on early diagnosis of ovarian cancer* Reviews new diagnostic techniques for ovarian disorders* Discusses latest information on reproductive technology* Presents translational treatment linking laboratory research with clinical medicine

Practical Medicinal Chemistry with Macrocycles

Author : Eric Marsault
Publisher : John Wiley & Sons
ISBN 13 : 1119092566
Total Pages : 617 pages
Book Rating : 4.1/5 (19 download)

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Book Synopsis Practical Medicinal Chemistry with Macrocycles by : Eric Marsault

Download or read book Practical Medicinal Chemistry with Macrocycles written by Eric Marsault and published by John Wiley & Sons. This book was released on 2017-09-12 with total page 617 pages. Available in PDF, EPUB and Kindle. Book excerpt: Including case studies of macrocyclic marketed drugs and macrocycles in drug development, this book helps medicinal chemists deal with the synthetic and conceptual challenges of macrocycles in drug discovery efforts. Provides needed background to build a program in macrocycle drug discovery –design criteria, macrocycle profiles, applications, and limitations Features chapters contributed from leading international figures involved in macrocyclic drug discovery efforts Covers design criteria, typical profile of current macrocycles, applications, and limitations

Molecular Biology of the Cell

Author :
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)

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Book Synopsis Molecular Biology of the Cell by :

Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Hormones and the Fetus

Author : J. R. Pasqualini
Publisher : Elsevier
ISBN 13 : 1483286681
Total Pages : 370 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Hormones and the Fetus by : J. R. Pasqualini

Download or read book Hormones and the Fetus written by J. R. Pasqualini and published by Elsevier. This book was released on 2013-10-22 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume One of Hormones and the Fetus contained a generalization of the role of hormones during fetal life. In this second volume, the main topics focus on hormonal binding to fetal and maternal plasma proteins, amniotic fluid and placenta; the presence of hormone receptors in the fetal compartment; and the mechanism of action of various hormones in different target tissues of the fetus and placenta. This up-to-date information is of major importance in the study of hormonal activity in fetal life, and the biological effect of hormones through the receptor. The mechanism of fetal sexual differentiation, in which hormones play an important role, is extensively covered.

Encyclopedia of Stress

Author : George Fink
Publisher : Academic Press
ISBN 13 : 0122267354
Total Pages : 793 pages
Book Rating : 4.1/5 (222 download)

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Book Synopsis Encyclopedia of Stress by : George Fink

Download or read book Encyclopedia of Stress written by George Fink and published by Academic Press. This book was released on 2000 with total page 793 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprised of nearly 400 entries by leading experts on the subject, "The Encyclopedia of Stress" covers almost every aspect and ramification of stress. The book explores the effects of stress on behavior, psychiatric and psychosomatic disorders, cardiovascular systems, reproductive function, and immune function, plus stress as a consequence of work, post-traumatic stress, and stress and predisposition to disease. (Social Sciences--Psychology)

Encyclopedia of Stress

Author :
Publisher : Academic Press
ISBN 13 : 0080569773
Total Pages : 793 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Encyclopedia of Stress by :

Download or read book Encyclopedia of Stress written by and published by Academic Press. This book was released on 2000-04-19 with total page 793 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stress is generally defined as a strain upon a bodily organ or mental power. Depending on its duration and intensity, stress can have short- or long-lasting effects: it has been linked to heart disease, immune deficiency, memory loss, behavioral disorders, and much more. These effects on the individual also have a major impact on health care costs and services, employee productivity, and even violent crime. The Encyclopedia of Stress is the first comprehensive reference source on stressors, the biological mechanisms involved in the stress response, the effects of activating the stress response mechanisms, and the disorders that may arise as a consequence of acute or chronic stress. While other books focus on specific aspects of stress, this three-volume set covers the entire spectrum of topics, with nearly 400 articles in all. In addition to the subjects traditionally associated with the hypothalamic-pituitary-adrenal axis (whereby the brain sends a message to the body to react), the Encyclopedia includes a wide range of related topics such as neuroimmune interactions, cytokines, enzymatic disorders, effects on the cardiovascular system, immunity and inflammation, and physical illnesses. It also goes beyond the biological aspects of stress to cover topics such as stress and behavior, psychiatric and psychosomatic disorders, workplace stress, post-traumatic stress, stress-reduction techniques, and current therapies. The Encyclopedia of Stress makes information easy to find and understand for a broad audience of researchers, clinicians, professionals, and students. Key Features * Presenting the first-ever encyclopedia on stress * Brings together the latest information on stressors, stress responses, and the disorders that can result * Covers stress from molecules to man to societies * Contains nearly 400 articles, covering a wide range of stress-related topics * Arranges topics in easily found alphabetical order * Supplements each article with a glossary and further reading list * Provides the most comprehensive coverage of stress available * Includes extensive cross-referencing between articles and a complete subject index * Covers hot topics, ranging from stress in the workplace and post-traumatic stress disorder to stress-related diseases * Edited by one of the world's leading authorities on stress * Written by more than 560 experts from 20 different countries * Appeals to a wide audience seeking information on topics within and outside their areas of expertise

Molecular Structure and Biological Activity of Steroids

Author : Martin Bohl
Publisher : CRC Press
ISBN 13 : 1351083252
Total Pages : 483 pages
Book Rating : 4.3/5 (51 download)

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Book Synopsis Molecular Structure and Biological Activity of Steroids by : Martin Bohl

Download or read book Molecular Structure and Biological Activity of Steroids written by Martin Bohl and published by CRC Press. This book was released on 2018-01-18 with total page 483 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Structure and Biological Activity of Steroids focuses on the indentification of steroid structural features that control particular biological effects. Steroid geometry plays a critical role in steroid activity; therefore, the results of X-ray crystallographic, NMR spectroscopic, and theoretical studies on structure-activity relationships form an integral part of the book. Well-established observations and proposed models are presented, summarizing knowledge of molecular features (e.g., steroid backbone structures, side-chain constitutions, substitution sites, configurations, hydrogen-bonding patterns) that can affect steroid action. The book also provides overviews about recent progress in various frontier fields of steroid research, including such areas as sex steroids, glucocorticoids, aromatase inhibitors, vitamin D metabolites, brassinosteroids, neuromuscular blocking agents, and cardiotonic steroids. Molecular Structure and Biological Activity of Steroids is a "must-have" resource for biochemists, pharmacologists, endocrinologists, biophysicists, and others actively involved in steroid research.

Endocrine Disruption Modeling

Author : James Devillers
Publisher : CRC Press
ISBN 13 : 1420076361
Total Pages : 420 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Endocrine Disruption Modeling by : James Devillers

Download or read book Endocrine Disruption Modeling written by James Devillers and published by CRC Press. This book was released on 2009-04-27 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: Uses Computational Tools to Simulate Endocrine Disruption PhenomenaEndocrine Disruption Modeling provides a practical overview of the current approaches for modeling endocrine activity and the related potential adverse effects they may induce on environmental and human health. Based on the extensive research of an international panel of contributor

An Introduction to Neuroendocrinology

Author : Richard E. Brown
Publisher : Cambridge University Press
ISBN 13 : 9780521426657
Total Pages : 434 pages
Book Rating : 4.4/5 (266 download)

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Book Synopsis An Introduction to Neuroendocrinology by : Richard E. Brown

Download or read book An Introduction to Neuroendocrinology written by Richard E. Brown and published by Cambridge University Press. This book was released on 1994-01-27 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is designed as an introductory text in neuroendocrinology; the study of the interaction between the brain and endocrine system and the influence of this on behaviour. The endocrine glands, pituitary gland and hypothalamus and their interactions and hormones are discussed. The action of steroid and thyroid hormone receptors and the regulation of target cell response to hormones is examined. The function of neuropeptides is discussed with respect to the neuroendocrine system and behaviour. The neuroimmune system and lymphokines are described and the interaction between the neuroendocrine and neuroimmune systems discussed. Finally, methods for studying hormonal influences on behaviour are outlined. Each chapter has review and essay questions designed for advanced students and honours or graduate students with a background in neuroscience, respectively.

The Steroid/Thyroid Hormone Receptor Family and Gene Regulation

Author : J. Carlstedt-Duke
Publisher : Birkhäuser
ISBN 13 : 3034854668
Total Pages : 360 pages
Book Rating : 4.0/5 (348 download)

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Book Synopsis The Steroid/Thyroid Hormone Receptor Family and Gene Regulation by : J. Carlstedt-Duke

Download or read book The Steroid/Thyroid Hormone Receptor Family and Gene Regulation written by J. Carlstedt-Duke and published by Birkhäuser. This book was released on 2013-11-21 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Second International CBT (Center for Biotechnology) Synposium was held in Stockholm November 4-5 1988 and had the title "The steroid/thyroid hoITIDne receptor family and gene regulation". This meeting contained contributions from most leading laboratories within the field of steroid/thyroid hOITIDne receptors and gave a very exciting perspective on the dynamic development of this i:ntx>rt. ant research field. Today all known steroid hoITIDne receptors have been cloned and sequenced and novel members of this supergene family are constantly being discovered. Sane of these new receptors remain to be characterized regarding the nature of their ligand. Access to probes for steroid receptors has enabled studies on mechanisms of regulation of receptor gene expression. Deletion and II'Altational analysis of steroid receptor cDNAs followed by expression in cells together with suitable reporter genes has yielded a detailed knowledge about the functional significance of the various domains the receptors are composed of. In certain cases, steroid resistance in patients have been shown to be due to point mutations in the corresponding steroid receptor genes resulting in non-functional receptors. The availability of receptor cDNAs also makes it possible to express receptors at high levels in procaryotic and eucaryotic cells. It is e. g. possible to express the DNA-binding domain of the glucocorticoid receptor in E. coli as a fusion protein with protein A which interacts specifically with DNA. Such studies are necessary for production of sufficient quantities of receptors to allow crystallization and X-ray crystallography for detailed structural information.

Handbook of Mass Spectra of Environmental Contaminants

Author : Ronald A. Hites
Publisher : CRC Press
ISBN 13 : 9780873715348
Total Pages : 952 pages
Book Rating : 4.7/5 (153 download)

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Book Synopsis Handbook of Mass Spectra of Environmental Contaminants by : Ronald A. Hites

Download or read book Handbook of Mass Spectra of Environmental Contaminants written by Ronald A. Hites and published by CRC Press. This book was released on 1992-06-10 with total page 952 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Mass Spectra of Environmental Contaminants, Second Edition is a collection of the electron impact mass spectra of 533 commonly encountered environmental pollutants. The compounds were selected from an analysis of several U.S. Environmental Protection Agency and World Health Organization databases. All data have been reviewed by a panel of experienced mass spectrometrists. To help identify unknown compounds, all spectra have been indexed by common chemical name, CAS registry number, exact molecular weight, and intense peaks. Completely revised and expanded, the Handbook of Mass Spectra of Environmental Contaminants, Second Edition, provides information essential to environmental laboratory specialists world-wide. This handbook is a collection of the electron impact mass spectra of 533 commonly encountered environmental pollutants, selected from U.S. Environmental Protection Agency and World Health Organization databases.

Proceedings of the Fourth Meeting of the International Study Group for Steroid Hormones

Author : International Study Group for Steroid Hormones. Meeting
Publisher : Franklin Book Company
ISBN 13 : 9780080175737
Total Pages : 331 pages
Book Rating : 4.1/5 (757 download)

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Book Synopsis Proceedings of the Fourth Meeting of the International Study Group for Steroid Hormones by : International Study Group for Steroid Hormones. Meeting

Download or read book Proceedings of the Fourth Meeting of the International Study Group for Steroid Hormones written by International Study Group for Steroid Hormones. Meeting and published by Franklin Book Company. This book was released on 1970 with total page 331 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research on Steroids contains the proceedings of the Fourth Meeting of the International Study Group for Steroid Hormones. The papers explore the production, chemical characterization, and metabolism of steroid hormones and their interactions with proteins. Topics range from the action of estradiol in vitro to water-soluble metabolites of estrogens, transport of steroids by proteins, and immunological aspects of steroid hormones. The binding of steroids by tissue proteins is also discussed, along with the use of specific plasma proteins for the determination of steroids. This volume is compris...

Androgen Excess Disorders in Women

Author : Ricardo Azziz
Publisher : Springer Science & Business Media
ISBN 13 : 1597451797
Total Pages : 460 pages
Book Rating : 4.5/5 (974 download)

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Book Synopsis Androgen Excess Disorders in Women by : Ricardo Azziz

Download or read book Androgen Excess Disorders in Women written by Ricardo Azziz and published by Springer Science & Business Media. This book was released on 2007-11-08 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of androgen excess disorders has advanced substantially since the original publication of this book. The Androgen Excess Society (AES) was founded to bring together investigators in the field. A better understanding of the screening, progression, and molecular genetics of nonclassic adrenal hyperplasia (NCAH) has improved the clinical care and diagnostic accuracy of these patients. New criteria for the diagnosis of the polycystic ovary syndrome (PCOS) were proposed in Rotterdam, criteria that have resulted in controversy and, hopefully, initiation of new studies. The association of insulin resistance with PCOS has been strengthened, and the role of metformin in tre- ing the infertility of the PCOS has been validated. Risks for diabetes and, more cont- versially, cardiovascular disease in women with PCOS have received substantial investigation. Our understanding of the epidemiology and economic impact of these disorders has expanded, emphasizing their critical importance. These are but a few highlights of how the terrain has changed in a relatively brief period of time. In keeping with these advances, the title of this book has been revised to reflect the growing importance of PCOS as the most prevalent androgen excess disorder in women, and arguably, as the one that might have the most serious adverse consequences for general health. There are fewer chapters to provide a more focused elucidation of the area. Several chapters were penned by new (and young) authors who are conducting cutting-edge research in the field.

3D QSAR in Drug Design

Author : Hugo Kubinyi
Publisher : Springer Science & Business Media
ISBN 13 : 0306468573
Total Pages : 413 pages
Book Rating : 4.3/5 (64 download)

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Book Synopsis 3D QSAR in Drug Design by : Hugo Kubinyi

Download or read book 3D QSAR in Drug Design written by Hugo Kubinyi and published by Springer Science & Business Media. This book was released on 2006-04-11 with total page 413 pages. Available in PDF, EPUB and Kindle. Book excerpt: Significant progress has been made in the study of three-dimensional quantitative structure-activity relationships (3D QSAR) since the first publication by Richard Cramer in 1988 and the first volume in the series. 3D QSAR in Drug Design. Theory, Methods and Applications, published in 1993. The aim of that early book was to contribute to the understanding and the further application of CoMFA and related approaches and to facilitate the appropriate use of these methods. Since then, hundreds of papers have appeared using the quickly developing techniques of both 3D QSAR and computational sciences to study a broad variety of biological problems. Again the editor(s) felt that the time had come to solicit reviews on published and new viewpoints to document the state of the art of 3D QSAR in its broadest definition and to provide visions of where new techniques will emerge or new appli- tions may be found. The intention is not only to highlight new ideas but also to show the shortcomings, inaccuracies, and abuses of the methods. We hope this book will enable others to separate trivial from visionary approaches and me-too methodology from in- vative techniques. These concerns guided our choice of contributors. To our delight, our call for papers elicited a great many manuscripts.