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Steroid Protein Interactions
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Book Synopsis Steroid-protein Interactions by : Ulrich Westphal
Download or read book Steroid-protein Interactions written by Ulrich Westphal and published by Springer. This book was released on 1971 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the story of steroid-protein interactions as one investigator sees it. Following the general concept of this monograph series, it emphasizes the results and interpretations obtained in the author's laboratory, and is therefore a subjective account. Recognizing, how ever, that the discussion of the subject would be incomplete if the material were limited to one scientist's work, the essential achieve ments of other investigators have been incorporated. An effort has thus been made to give a balanced presentation and to enable the reader to see in perspective the varied facets of the interactions between steroids and proteins. Since this is the first comprehensive treatment of the topic, it seems appropriate to go to the roots, and try to find out how it all started. The first chapters, therefore, take the reader to the laboratories of those who very early conceived the significance of the attachment of dyes, drugs, and other conspicuous molecules to those colloids called proteins. The discovery of the steroid hormones set the stage for meaningful investigation of their interaction with proteins of various origins and functions - a process which is continuing today with increasing vigor.
Book Synopsis Steroid-Protein Interactions by : Ulrich Westphal
Download or read book Steroid-Protein Interactions written by Ulrich Westphal and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 578 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the story of steroid-protein interactions as one investigator sees it. Following the general concept of this monograph series, it emphasizes the results and interpretations obtained in the author's laboratory, and is therefore a subjective account. Recognizing, how ever, that the discussion of the subject would be incomplete if the material were limited to one scientist's work, the essential achieve ments of other investigators have been incorporated. An effort has thus been made to give a balanced presentation and to enable the reader to see in perspective the varied facets of the interactions between steroids and proteins. Since this is the first comprehensive treatment of the topic, it seems appropriate to go to the roots, and try to find out how it all started. The first chapters, therefore, take the reader to the laboratories of those who very early conceived the significance of the attachment of dyes, drugs, and other conspicuous molecules to those colloids called proteins. The discovery of the steroid hormones set the stage for meaningful investigation of their interaction with proteins of various origins and functions - a process which is continuing today with increasing vigor.
Book Synopsis Steroid-Protein Interactions II by : Ulrich Westphal
Download or read book Steroid-Protein Interactions II written by Ulrich Westphal and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 620 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :International Study Group for Steroid Hormones. Meeting Publisher :Franklin Book Company ISBN 13 :9780080175737 Total Pages :331 pages Book Rating :4.1/5 (757 download)
Book Synopsis Proceedings of the Fourth Meeting of the International Study Group for Steroid Hormones by : International Study Group for Steroid Hormones. Meeting
Download or read book Proceedings of the Fourth Meeting of the International Study Group for Steroid Hormones written by International Study Group for Steroid Hormones. Meeting and published by Franklin Book Company. This book was released on 1970 with total page 331 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research on Steroids contains the proceedings of the Fourth Meeting of the International Study Group for Steroid Hormones. The papers explore the production, chemical characterization, and metabolism of steroid hormones and their interactions with proteins. Topics range from the action of estradiol in vitro to water-soluble metabolites of estrogens, transport of steroids by proteins, and immunological aspects of steroid hormones. The binding of steroids by tissue proteins is also discussed, along with the use of specific plasma proteins for the determination of steroids. This volume is compris...
Book Synopsis Molecular Biology of Steroid and Nuclear Hormone Receptors by : Leonard Freedman
Download or read book Molecular Biology of Steroid and Nuclear Hormone Receptors written by Leonard Freedman and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: Intracellular Receptors: New Instruments for a Symphony of Signals In the late eighteenth century, it was proposed on theoretical grounds that each of the body's organs, beginning with the brain, must be "a factory and laboratory of a specific humor which it returns to the blood", and that these circulating signals "are indispensable for the life of the whole" (Bordeu 1775). During the nineteenth cen tury, some remarkable physiological experiments revealed the actions of humoral factors that affected the for and function of multiple tissues, organs and organ sys tems within the body (Berthold 1849); much later, the chemical and molecular na ture of some of those factors was determined. Against this deep historical backdrop of the founding studies of intercellular signaling, molecular biology sprang into existence a mere forty years ago, rooted in the revelation of regulable gene expression in bacteria. But contemporaneous with those classical analyses of transcriptional regulation of the lactose operon, the mod em era of signal transduction was inaugurated by the identification of cAMP as a second messenger -- an intracellular mediator of hormonal activation of glycogen catabolism (Sutherland and RaIl 1960). Later in that same decade, it emerged that cAMP is a critical signal not only in metazoans, but even in bacteria, where it serves an analogous function as a critical switch that activates expression of genes re quired for catabolism of complex carbon sources, including those of the lactose operon.
Book Synopsis Steroid–Cell Interactions by : R. J. B. King
Download or read book Steroid–Cell Interactions written by R. J. B. King and published by Elsevier. This book was released on 2014-05-20 with total page 459 pages. Available in PDF, EPUB and Kindle. Book excerpt: Steroid–Cell Interactions describes the processes involved in the intracellular binding of steroids (and related compounds) in mammalian cells. Serum binding proteins and steroid-immunoglobulin interaction are also discussed, along with the relationship of these binding processes to the biological action of the steroid. This book consists of 10 chapters and begins by presenting an elementary account of the factors contributing to the interaction between a steroid hormone and another molecule. The discussion then turns to the three types of methods used to study the interaction between steroids and tissue receptors: cell fractionation, autoradiography, and the separation of specifically and non-specifically bound steroids. The next chapter deals with the metabolism of steroid hormones in relation to their binding and mechanism of action, focusing on testosterone and progesterone. The reader is also introduced to the intracellular binding of androgens, glucocorticoids, mineralocorticoids, and estrogens and to how binding is related to biological activity. The final chapter reviews the clinical and immunological data relevant to steroid-protein binding. This text will be of interest to students and practitioners of biology, biochemistry, and physiology.
Book Synopsis Steroid Hormone Action by : Malcolm G. Parker
Download or read book Steroid Hormone Action written by Malcolm G. Parker and published by IRL Press. This book was released on 1993 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a detailed overview of the mechanisms by which steroid hormones regulate gene activity in target cells. It should be of interest to molecular biologists, endocrinologists, pharmacologists and clinicians interested in gene regulation hormones and steroid antagonists.
Book Synopsis An Introduction to Neuroendocrinology by : Richard E. Brown
Download or read book An Introduction to Neuroendocrinology written by Richard E. Brown and published by Cambridge University Press. This book was released on 1994-01-27 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is designed as an introductory text in neuroendocrinology; the study of the interaction between the brain and endocrine system and the influence of this on behaviour. The endocrine glands, pituitary gland and hypothalamus and their interactions and hormones are discussed. The action of steroid and thyroid hormone receptors and the regulation of target cell response to hormones is examined. The function of neuropeptides is discussed with respect to the neuroendocrine system and behaviour. The neuroimmune system and lymphokines are described and the interaction between the neuroendocrine and neuroimmune systems discussed. Finally, methods for studying hormonal influences on behaviour are outlined. Each chapter has review and essay questions designed for advanced students and honours or graduate students with a background in neuroscience, respectively.
Book Synopsis Diagnosis and Management of Ovarian Disorders by : Albert Altchek
Download or read book Diagnosis and Management of Ovarian Disorders written by Albert Altchek and published by Elsevier. This book was released on 2003-09-04 with total page 595 pages. Available in PDF, EPUB and Kindle. Book excerpt: This updated second edition of Diagnosis and Management of Ovarian Disorders provides thorough, yet succinct insight into the ever-changing realm of ovarian disorders. It presents a novel multidisciplinary approach to the subject as described by clinicians, surgeons, pathologists, basic scientists and related medical researchers. Topics covered include reproductive technology, early diagnosis of ovarian cancer, and management of menopause among others. The breadth of information provided by this book will appeal to clinicians and researchers involved in the study and treatment of ovarian disorders.KEY FEATURES* Includes updated information on early diagnosis of ovarian cancer* Reviews new diagnostic techniques for ovarian disorders* Discusses latest information on reproductive technology* Presents translational treatment linking laboratory research with clinical medicine
Book Synopsis Practical Medicinal Chemistry with Macrocycles by : Eric Marsault
Download or read book Practical Medicinal Chemistry with Macrocycles written by Eric Marsault and published by John Wiley & Sons. This book was released on 2017-09-12 with total page 617 pages. Available in PDF, EPUB and Kindle. Book excerpt: Including case studies of macrocyclic marketed drugs and macrocycles in drug development, this book helps medicinal chemists deal with the synthetic and conceptual challenges of macrocycles in drug discovery efforts. Provides needed background to build a program in macrocycle drug discovery –design criteria, macrocycle profiles, applications, and limitations Features chapters contributed from leading international figures involved in macrocyclic drug discovery efforts Covers design criteria, typical profile of current macrocycles, applications, and limitations
Book Synopsis Research on Steroids by : M. Finkelstein
Download or read book Research on Steroids written by M. Finkelstein and published by Elsevier. This book was released on 2013-10-22 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research on Steroids contains the proceedings of the Fourth Meeting of the International Study Group for Steroid Hormones. The papers explore the production, chemical characterization, and metabolism of steroid hormones and their interactions with proteins. Topics range from the action of estradiol in vitro to water-soluble metabolites of estrogens, transport of steroids by proteins, and immunological aspects of steroid hormones. The binding of steroids by tissue proteins is also discussed, along with the use of specific plasma proteins for the determination of steroids. This volume is comprised of 38 chapters and begins with an overview of the general aspects of steroid-protein interaction, followed by a discussion on quantitative studies of steroid binding proteins; aromatization of testosterone by human placenta enzymes; relationship between plasma binding and 5a-reduction of testosterone; cortisol-binding capacity of plasma transcortin in subjects treated with various anabolic steroids; and plasma testosterone binding capacity and estrogen excretion in normal and pathological pregnancies. Subsequent chapters deal with the interaction between estrogenic and carcinogenic substances in the rat mammary gland; influence of steroid production on serum albumin in Cushing's syndrome; and nuclear estradiol binding proteins in the uterus. This book will be of interest to biochemists, biologists, and physiologists.
Book Synopsis Steroid-protein interactions : basic and clinical aspects : Second International Symposium on Binding Proteins by : Roberto Frairia
Download or read book Steroid-protein interactions : basic and clinical aspects : Second International Symposium on Binding Proteins written by Roberto Frairia and published by . This book was released on 1988 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Extrasynaptic GABAA Receptors by : Adam C. Errington
Download or read book Extrasynaptic GABAA Receptors written by Adam C. Errington and published by Springer. This book was released on 2014-09-22 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt: GABA is the principal inhibitory neurotransmitter in the CNS and acts via GABAA and GABAB receptors. Recently, a novel form of GABAA receptor-mediated inhibition, termed “tonic” inhibition, has been described. Whereas synaptic GABAA receptors underlie classical “phasic” GABAA receptor-mediated inhibition (inhibitory postsynaptic currents), tonic GABAA receptor-mediated inhibition results from the activation of extrasynaptic receptors by low concentrations of ambient GABA. Extrasynaptic GABAA receptors are composed of receptor subunits that convey biophysical properties ideally suited to the generation of persistent inhibition and are pharmacologically and functionally distinct from their synaptic counterparts. This book highlights ongoing work examining the properties of recombinant and native extrasynaptic GABAA receptors and their preferential targeting by endogenous and clinically relevant agents. In addition, it emphasizes the important role of extrasynaptic GABAA receptors in GABAergic inhibition throughout the CNS and identifies them as a major player in both physiological and pathophysiological processes.
Book Synopsis Steroid Dynamics by : Gregory Pincus
Download or read book Steroid Dynamics written by Gregory Pincus and published by Academic Press. This book was released on 2013-10-22 with total page 596 pages. Available in PDF, EPUB and Kindle. Book excerpt: Steroid Dynamics compiles papers presented at the Symposium on the Dynamics of Steroid Hormones held in Tokyo, in May 1965. This compilation discusses the effect of LH and ACTH on production and excretion of testosterone in vivo, estrogen receptors in target tissues, and influence of morphine on corticoid production. The binding of steroids to follicular fluid proteins, conjugation and excretion of aldosterone, and active cholesterol pool for corticodogenesis in the rat adrenal are also elaborated. This book likewise covers the dynamics of steroid hormone distribution in the body, biosynthesis of steroids in testicular tissue in vitro, and isotopic dilution methods for the estimation of rates of secretion of the steroid hormones. This publication is a good reference for endocrinologists, biochemists, and medical practitioners interested in steroid dynamics.
Book Synopsis Advances in Research and Applications by :
Download or read book Advances in Research and Applications written by and published by Elsevier. This book was released on 2000-01-27 with total page 521 pages. Available in PDF, EPUB and Kindle. Book excerpt: Under the capable and qualified editorial leadership of Dr. Gerald Litwack, Vitamins and Hormones continues to publish cutting-edge reviews of interest to endocrinologists, biochemists, nutritionists, pharmacologists, cell biologists, and molecular biologists. First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. In the early days of the Serial, the subjects of vitamins and hormones were quite distinct. Now, new discoveries have proved that several of the vitamins function as hormones and many of the substances inferred by the title of the serial function in signal transduction processes. Accordingly, the Editor-in-Chief has expanded the scope of the serial to reflect this newer understanding of function-structure relationships in cellular communication. The Editorial Board now reflects expertise in the field of hormone action, vitamin action, X-ray crystal structure, physiology, and enzyme mechanisms.
Book Synopsis Plasma Protein Turnover by : Romano Bianchi
Download or read book Plasma Protein Turnover written by Romano Bianchi and published by Springer. This book was released on 1976-06-18 with total page 441 pages. Available in PDF, EPUB and Kindle. Book excerpt:
