Stereoselective Synthesis of Tetrahydrofuran and Tetrahydropyran Derivatives by Use of Asymmetric Horner-Wadsworth-Emmons and Ring Closure Reactions

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ISBN 13 : 9789985565247
Total Pages : 182 pages
Book Rating : 4.5/5 (652 download)

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Book Synopsis Stereoselective Synthesis of Tetrahydrofuran and Tetrahydropyran Derivatives by Use of Asymmetric Horner-Wadsworth-Emmons and Ring Closure Reactions by : Lauri Vares

Download or read book Stereoselective Synthesis of Tetrahydrofuran and Tetrahydropyran Derivatives by Use of Asymmetric Horner-Wadsworth-Emmons and Ring Closure Reactions written by Lauri Vares and published by . This book was released on 2000 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Organic Reaction Mechanisms 2002

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Publisher : John Wiley & Sons
ISBN 13 : 0470022043
Total Pages : 664 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Organic Reaction Mechanisms 2002 by : A. C. Knipe

Download or read book Organic Reaction Mechanisms 2002 written by A. C. Knipe and published by John Wiley & Sons. This book was released on 2007-01-30 with total page 664 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is the 38th in this classical series. In every volume the content is divided in the different classes of organic reaction mechanisms: Reaction of Aldehydes and Ketones and their Derivatives Reactions of Carboxylic, Phosphoric, and Sulfonic Acids and their Derivatives Oxidation and Reduction Carbenes and Nitrenes Nucleophilic Aromatic Substitution Electrophilic Aromatic Substitution Carbocations Nucleophilic Aliphatic Substitution Carbanions and Electrophilic Aliphatic Substitution Elimination Reactions Radical Reactions Addition Reactions: Polar Addition Addition Reactions: Cycloadditions Molecular Rearrangements An experienced team of authors is compiling these reviews every year, so that the reader can rely on a continuing quality of selection and presentation. As a new service to the reader all reaction mechanisms leading to stereospecific products are highlighted. This reflects the needs of the organic synthetic community with leads to chiral reactions. Detailed author and subject indexes help the reader to find the information they are looking for.

Index Medicus

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ISBN 13 :
Total Pages : 1748 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Index Medicus by :

Download or read book Index Medicus written by and published by . This book was released on 2003 with total page 1748 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.

Stereoselective Synthesis

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Publisher : Springer Science & Business Media
ISBN 13 : 3642784968
Total Pages : 147 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis Stereoselective Synthesis by : Eckhard Ottow

Download or read book Stereoselective Synthesis written by Eckhard Ottow and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 147 pages. Available in PDF, EPUB and Kindle. Book excerpt: Devising methods and reagents for stereoselective synthesis is an intellectually demanding venture. Six experts on diastereo- and enantioselective synthesis contributed their papers to this volume. They were presented at a symposium on stereoselective synthesis to honour Professor Dr. Dr. h.c. Rudolf Wiechert's achievements in medicinal chemistry research. The symposium was organized by the Schering AG on the occasion of Professor Wiechert's 65th birthday.

The Stereoselective Synthesis of Tetrahydrofurans from Diazoesters and Glyceraldehyde Derivatives

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ISBN 13 :
Total Pages : 292 pages
Book Rating : 4.3/5 (121 download)

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Book Synopsis The Stereoselective Synthesis of Tetrahydrofurans from Diazoesters and Glyceraldehyde Derivatives by : Daniel Salem Bernier

Download or read book The Stereoselective Synthesis of Tetrahydrofurans from Diazoesters and Glyceraldehyde Derivatives written by Daniel Salem Bernier and published by . This book was released on 2001 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Substituent, Temperature and Solvent Effects on the Alkaline Hydrolysis of Substituted Phenyl and Alkyl Esters of Benzoic Acid

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ISBN 13 :
Total Pages : 162 pages
Book Rating : 4.E/5 ( download)

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Book Synopsis Substituent, Temperature and Solvent Effects on the Alkaline Hydrolysis of Substituted Phenyl and Alkyl Esters of Benzoic Acid by : Mare Piirsalu

Download or read book Substituent, Temperature and Solvent Effects on the Alkaline Hydrolysis of Substituted Phenyl and Alkyl Esters of Benzoic Acid written by Mare Piirsalu and published by . This book was released on 2003 with total page 162 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Stereoselective Synthesis of Tetrahydrofurans and Tetrahydropyrans

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Publisher :
ISBN 13 :
Total Pages : 356 pages
Book Rating : 4.3/5 (121 download)

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Book Synopsis Stereoselective Synthesis of Tetrahydrofurans and Tetrahydropyrans by : Nahla Ahmed Elsaid

Download or read book Stereoselective Synthesis of Tetrahydrofurans and Tetrahydropyrans written by Nahla Ahmed Elsaid and published by . This book was released on 2001 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Classics in Stereoselective Synthesis

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Publisher : John Wiley & Sons
ISBN 13 : 9783527324521
Total Pages : 664 pages
Book Rating : 4.3/5 (245 download)

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Book Synopsis Classics in Stereoselective Synthesis by : Erick M. Carreira

Download or read book Classics in Stereoselective Synthesis written by Erick M. Carreira and published by John Wiley & Sons. This book was released on 2009-02-09 with total page 664 pages. Available in PDF, EPUB and Kindle. Book excerpt: Die wichtigsten und nützlichsten Methoden der modernen stereoselektiven Synthese sind in diesem Band zusammengefasst. Viele anschauliche Beispiele für die Darstellung von Wirkstoffen und Naturstoffen regen zur gezielten Abwandlung und Integration in eigene Synthesewege an. Dabei geht es den Autoren weniger darum, das Gebiet in seiner Gesamtheit darzustellen; vielmehr versuchen sie, die wirklich grundlegenden Ansätze auszuwählen, die jeder organische Synthesechemiker kennen und anwenden sollte.

Stereoselective Synthesis

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ISBN 13 :
Total Pages : 552 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Stereoselective Synthesis by : Robert S. Atkinson

Download or read book Stereoselective Synthesis written by Robert S. Atkinson and published by . This book was released on 1995-09-13 with total page 552 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduces a new classification for stereoselective reactions based on the number of chiral centres contained in the starting material and the product. Based on stereochemical terms, this classification enables users to apply methods for the synthesis of target molecules.

Stereoselective Synthesis

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Publisher : John Wiley & Sons
ISBN 13 : 3527615687
Total Pages : 386 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Stereoselective Synthesis by : Mihály Nógrádi

Download or read book Stereoselective Synthesis written by Mihály Nógrádi and published by John Wiley & Sons. This book was released on 2008-07-11 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: The state-of-the-art in stereoselective synthesis! Thoroughly revised and updated, this enlarged second edition offers a plethora of valuable information on methods and reagents in stereoselective synthesis. Methods have been selected for high efficiency and selectivity; mechanistic aspects are treated succinctly, with a strong emphasis on practical applications. For this new edition, material has been added on * homogeneous diastereoselective hydrogenations * enantioselective oxidations * novel, efficient chiral auxiliaries Much of the information given is presented in figures and tables, which makes the book a valuable reference work for the practically minded organic chemist. From reviews of the first edition: 'The extensive material in the volume should prove particularly useful to anyone involved in synthetic chemistry or teaching a course in organic chemistry.' Journal of Medicinal Chemistry 'With nearly 1400 references cited, the book contains a wealth of information and should be a useful addition to the chemist's library.' The American Scientist

Stereoselective Synthesis of Drugs and Natural Products

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Publisher : John Wiley & Sons
ISBN 13 : 1118628330
Total Pages : 1836 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis Stereoselective Synthesis of Drugs and Natural Products by : Vasyl Andrushko

Download or read book Stereoselective Synthesis of Drugs and Natural Products written by Vasyl Andrushko and published by John Wiley & Sons. This book was released on 2013-08-16 with total page 1836 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brings together the best tested and proven stereoselective synthetic methods Both the chemical and pharmaceutical industries are increasingly dependent on stereoselective synthetic methods and strategies for the generation of new chiral drugs and natural products that offer specific 3-D structures. With the publication of Stereoselective Synthesis of Drugs and Natural Products, researchers can turn to this comprehensive two-volume work to guide them through all the core methods for the synthesis of chiral drugs and natural products. Stereoselective Synthesis of Drugs and Natural Products features contributions from an international team of synthetic chemists and pharmaceutical and natural product researchers. These authors have reviewed the tremendous body of literature in the field in order to compile a set of reliable, tested, and proven methods alongside step-by-step guidance. This practical resource not only explores synthetic methodology, but also reaction mechanisms and applications in medicinal chemistry and drug discovery. The publication begins with an introductory chapter covering general principles and methodologies, nomenclature, and strategies of stereoselective synthesis. Next, it is divided into three parts: Part One: General Methods and Strategies Part Two: Stereoselective Synthesis by Bond Formation including C-C bond formation C-H bond formation C-O bond formation C-N bond formation Other C-heteroatom formation and other bond formation Part Three: Methods of Analysis and Chiral Separation References in every chapter serve as a gateway to the literature in the field. With this publication as their guide, chemists involved in the stereoselective synthesis of drugs and natural products now have a single, expertly edited source for all the methods they need.

The Regio- and Stereoselective Synthesis of 2,3,5-trisubstituted Tetrahydrofurans Via Cyclization of Epoxy Diols and Total Synthesis of the Proposed Structures of Mucoxin

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ISBN 13 :
Total Pages : 766 pages
Book Rating : 4.3/5 (129 download)

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Book Synopsis The Regio- and Stereoselective Synthesis of 2,3,5-trisubstituted Tetrahydrofurans Via Cyclization of Epoxy Diols and Total Synthesis of the Proposed Structures of Mucoxin by : Radha Sridhar Narayan

Download or read book The Regio- and Stereoselective Synthesis of 2,3,5-trisubstituted Tetrahydrofurans Via Cyclization of Epoxy Diols and Total Synthesis of the Proposed Structures of Mucoxin written by Radha Sridhar Narayan and published by . This book was released on 2004 with total page 766 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Stereoselective Synthesis of Substituted Tetrahydrofurans and Studies of Myrmicarin Alkaloids

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Publisher :
ISBN 13 :
Total Pages : 526 pages
Book Rating : 4.3/5 (121 download)

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Book Synopsis Stereoselective Synthesis of Substituted Tetrahydrofurans and Studies of Myrmicarin Alkaloids by : Xuelei Qian

Download or read book Stereoselective Synthesis of Substituted Tetrahydrofurans and Studies of Myrmicarin Alkaloids written by Xuelei Qian and published by . This book was released on 2006 with total page 526 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Principles of Asymmetric Synthesis

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Publisher : Elsevier
ISBN 13 : 0080514774
Total Pages : 395 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Principles of Asymmetric Synthesis by : R.E. Gawley

Download or read book Principles of Asymmetric Synthesis written by R.E. Gawley and published by Elsevier. This book was released on 1996-11-21 with total page 395 pages. Available in PDF, EPUB and Kindle. Book excerpt: The world is chiral. Most of the molecules in it are chiral, and asymmetric synthesis is an important means by which enantiopure chiral molecules may be obtained for study and sale. Using examples from the literature of asymmetric synthesis (more than 1300 references), the aim of this book is to present a detailed analysis of the factors that govern stereoselectivity in organic reactions. It is important to note that the references were each individually checked by the authors to verify relevance to the topics under discussion. The study of stereoselectivity has evolved from issues of diastereoselectivity, through auxiliary-based methods for the synthesis of enantiomerically pure compounds (diastereoselectivity followed by separation and auxiliary cleavage), to asymmetric catalysis. In the latter instance, enantiomers (not diastereomers) are the products, and highly selective reactions and modern purification techniques allow preparation - in a single step - of chiral substances in 99% ee for many reaction types. After an explanation of the basic physical-organic principles of stereoselectivity, the authors provide a detailed, annotated glossary of stereochemical terms. A chapter on "Analytical Methods" provides a critical overview of the most common methods for analysis of stereoisomers. The authors then follow the 'tried-and-true' format of grouping the material by reaction type. Thus, there are four chapters on carbon-carbon bond forming reactions (enolate alkylations, organometal additions to carbonyls, aldol and Michael reactions, and cycloadditions and rearrangements), one chapter on reductions and hydroborations (carbon-hydrogen bond forming reactions), and one on oxidations (carbon-oxygen and carbon-nitrogen bond forming reactions). Leading references are provided to natural product synthesis that have been accomplished using a given reaction as a key step. In addition to tables of examples that show high selectivity, a transition state analysis is presented to explain - to the current level of understanding - the stereoselectivity of each reaction. In one case (Cram's rule) the evolution of the current theory is detailed from its first tentative (1952) postulate to the current Felkin-Anh-Heathcock formalism. For other reactions, only the currently accepted rationale is presented. Examination of these rationales also exposes the weaknesses of current theories, in that they cannot always explain the experimental observations. These shortcomings provide a challenge for future mechanistic investigations.

Development of Novel Methodology for the Stereoselective Synthesis of Tetrahydrofurans Via 1,1-carbon Dipole Annulation

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ISBN 13 :
Total Pages : 392 pages
Book Rating : 4.3/5 (121 download)

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Book Synopsis Development of Novel Methodology for the Stereoselective Synthesis of Tetrahydrofurans Via 1,1-carbon Dipole Annulation by : Stephen Lavander White

Download or read book Development of Novel Methodology for the Stereoselective Synthesis of Tetrahydrofurans Via 1,1-carbon Dipole Annulation written by Stephen Lavander White and published by . This book was released on 2001 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Stereoselective Synthesis of Highly Functionalized Tetrahydropyran Rings

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ISBN 13 : 9780549714866
Total Pages : 286 pages
Book Rating : 4.7/5 (148 download)

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Book Synopsis Stereoselective Synthesis of Highly Functionalized Tetrahydropyran Rings by : Megan Lesley Bolla

Download or read book Stereoselective Synthesis of Highly Functionalized Tetrahydropyran Rings written by Megan Lesley Bolla and published by . This book was released on 2008 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: Described in this dissertation are several methods developed for the stereoselective synthesis of tetrahydropyrans rings. Initially, an effort to expand the Mukaiyama Aldol-Prins cyclization reaction to disubstituted (E)-enol ethers was explored. The Mukaiyama-Michael cascade reaction was then discovered by a fortuitous result. Investigating this method provided an unexpected tetrahydropyran product containing 2,6-trans geometry, and is rationalized considering both steric and electronic effects. Finally, a two-step [4+2] inverse demand HDA annulation reaction and rearrangement was developed for the diastereoselective synthesis of 2,4,5,6- tetra-substituted tetrahydropyran rings.

Stereoselective Synthesis of Tetrahydrofurans and Triazolines

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Publisher :
ISBN 13 :
Total Pages : 302 pages
Book Rating : 4.3/5 (121 download)

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Book Synopsis Stereoselective Synthesis of Tetrahydrofurans and Triazolines by : Stephanie Z. Shaw

Download or read book Stereoselective Synthesis of Tetrahydrofurans and Triazolines written by Stephanie Z. Shaw and published by . This book was released on 2001 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: