Status Quo and Future Perspectives of Molecular Diagnostics in Dermatology

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Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (138 download)

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Book Synopsis Status Quo and Future Perspectives of Molecular Diagnostics in Dermatology by : Christoffer Gebhardt

Download or read book Status Quo and Future Perspectives of Molecular Diagnostics in Dermatology written by Christoffer Gebhardt and published by . This book was released on 2023 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Abstract: Molecular diagnostics (MDx) has become an indispensable pillar of diagnostics in dermatology. Modern sequencing technologies allow for identification of rare genodermatoses, analysis of somatic mutations in melanoma are prerequisite for targeted therapies, and cutaneous infectious pathogens are quickly detected by PCR and other amplification methods. However, to push innovation in molecular diagnostics and tackle so far unmet clinical needs, research activities need to be bundled and the pipeline from idea to MDx product clearly rolled out. Only then, the requirements for technical validity and clinical utility of novel biomarkers can be fulfilled and the long-term vision of personalized medicine will be realized

Molecular Diagnostics for Dermatology

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Publisher : Springer Science & Business
ISBN 13 : 364254066X
Total Pages : 370 pages
Book Rating : 4.6/5 (425 download)

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Book Synopsis Molecular Diagnostics for Dermatology by : Gregory A. Hosler

Download or read book Molecular Diagnostics for Dermatology written by Gregory A. Hosler and published by Springer Science & Business. This book was released on 2014-04-30 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular diagnostics is an exploding field, and recent advances in our understanding of the molecular basis of disease have provided a platform for the development of new diagnostic tests as well as tests to predict tumor behavior and potential response to targeted therapy. This textbook provides a reference and practical guide to molecular diagnostics for dermatologists and dermatopathologists. It outlines our current understanding of the molecular underpinnings of dermatologic disease, describes the appropriate use of currently available molecular tests, and explains the interpretation of these tests in the context of diagnosis and management. Tests relating to various disorders are covered, including but not confined to melanoma, genodermatoses, and infectious disease. Pitfalls are highlighted and user-friendly algorithmic approaches, presented.

Molecular Diagnostics in Dermatology and Dermatopathology

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Publisher : Springer Science & Business Media
ISBN 13 : 1607611716
Total Pages : 480 pages
Book Rating : 4.6/5 (76 download)

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Book Synopsis Molecular Diagnostics in Dermatology and Dermatopathology by : Michael J. Murphy

Download or read book Molecular Diagnostics in Dermatology and Dermatopathology written by Michael J. Murphy and published by Springer Science & Business Media. This book was released on 2011-03-24 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Diagnostics in Dermatology and Dermatopathology presents the basics of molecular biology and molecular diagnostic methods most commonly used in the clinical laboratory, with an emphasis on the concepts and testing most relevant to dermatological diseases. Topics include the integration of newer diagnostic and prognostic techniques with ‘traditional’ histologic approaches, and discussions of regulatory, ethical, legal, economic issues and ‘newer’ technologies. This important diagnostic tool outlines the clinically relevant uses (i.e.; diagnostic, staging and/or prognostic) applications of these techniques in the field of dermatology. Molecular studies that investigate the pathogenesis of skin diseases will be excluded, unless they also have a direct diagnostic utility. The book will be of interest to practicing pathologists, dermatology and pathology residents, dermatologists, and dermatopathologists.

The Genetics of Male Infertility

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Publisher : Springer Science & Business Media
ISBN 13 : 1597451762
Total Pages : 337 pages
Book Rating : 4.5/5 (974 download)

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Book Synopsis The Genetics of Male Infertility by : Douglas T. Carrell

Download or read book The Genetics of Male Infertility written by Douglas T. Carrell and published by Springer Science & Business Media. This book was released on 2007-11-08 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book, twenty-one researchers and clinicians review the study of the genetics of male infertility, the tools available in the laboratory and clinic, the current state of knowledge, and the future of research and translation into clinical diagnostics and treatments. New tools discussed are discussed. This book therefore serves as a guide to evidence-based clinical applications, and a preview of future possibilities.

Dietary Supplements

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Publisher :
ISBN 13 :
Total Pages : 32 pages
Book Rating : 4.:/5 (31 download)

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Book Synopsis Dietary Supplements by : United States. Federal Trade Commission. Bureau of Consumer Protection

Download or read book Dietary Supplements written by United States. Federal Trade Commission. Bureau of Consumer Protection and published by . This book was released on 1998 with total page 32 pages. Available in PDF, EPUB and Kindle. Book excerpt:

WHO Guidelines on Hand Hygiene in Health Care

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Publisher : World Health Organization
ISBN 13 : 9789241597906
Total Pages : 0 pages
Book Rating : 4.5/5 (979 download)

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Book Synopsis WHO Guidelines on Hand Hygiene in Health Care by : World Health Organization

Download or read book WHO Guidelines on Hand Hygiene in Health Care written by World Health Organization and published by World Health Organization. This book was released on 2009 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The WHO Guidelines on Hand Hygiene in Health Care provide health-care workers (HCWs), hospital administrators and health authorities with a thorough review of evidence on hand hygiene in health care and specific recommendations to improve practices and reduce transmission of pathogenic microorganisms to patients and HCWs. The present Guidelines are intended to be implemented in any situation in which health care is delivered either to a patient or to a specific group in a population. Therefore, this concept applies to all settings where health care is permanently or occasionally performed, such as home care by birth attendants. Definitions of health-care settings are proposed in Appendix 1. These Guidelines and the associated WHO Multimodal Hand Hygiene Improvement Strategy and an Implementation Toolkit (http://www.who.int/gpsc/en/) are designed to offer health-care facilities in Member States a conceptual framework and practical tools for the application of recommendations in practice at the bedside. While ensuring consistency with the Guidelines recommendations, individual adaptation according to local regulations, settings, needs, and resources is desirable. This extensive review includes in one document sufficient technical information to support training materials and help plan implementation strategies. The document comprises six parts.

Conflict of Interest in Medical Research, Education, and Practice

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Publisher : National Academies Press
ISBN 13 : 0309145449
Total Pages : 436 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Conflict of Interest in Medical Research, Education, and Practice by : Institute of Medicine

Download or read book Conflict of Interest in Medical Research, Education, and Practice written by Institute of Medicine and published by National Academies Press. This book was released on 2009-09-16 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: Collaborations of physicians and researchers with industry can provide valuable benefits to society, particularly in the translation of basic scientific discoveries to new therapies and products. Recent reports and news stories have, however, documented disturbing examples of relationships and practices that put at risk the integrity of medical research, the objectivity of professional education, the quality of patient care, the soundness of clinical practice guidelines, and the public's trust in medicine. Conflict of Interest in Medical Research, Education, and Practice provides a comprehensive look at conflict of interest in medicine. It offers principles to inform the design of policies to identify, limit, and manage conflicts of interest without damaging constructive collaboration with industry. It calls for both short-term actions and long-term commitments by institutions and individuals, including leaders of academic medical centers, professional societies, patient advocacy groups, government agencies, and drug, device, and pharmaceutical companies. Failure of the medical community to take convincing action on conflicts of interest invites additional legislative or regulatory measures that may be overly broad or unduly burdensome. Conflict of Interest in Medical Research, Education, and Practice makes several recommendations for strengthening conflict of interest policies and curbing relationships that create risks with little benefit. The book will serve as an invaluable resource for individuals and organizations committed to high ethical standards in all realms of medicine.

Metal Oxide Nanoparticles, 2 Volume Set

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Publisher : John Wiley & Sons
ISBN 13 : 1119436745
Total Pages : 903 pages
Book Rating : 4.1/5 (194 download)

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Book Synopsis Metal Oxide Nanoparticles, 2 Volume Set by : Oliver Diwald

Download or read book Metal Oxide Nanoparticles, 2 Volume Set written by Oliver Diwald and published by John Wiley & Sons. This book was released on 2021-09-14 with total page 903 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metal Oxide Nanoparticles A complete nanoparticle resource for chemists and industry professionals Metal oxide nanoparticles are integral to a wide range of natural and technological processes—from mineral transformation to electronics. Additionally, the fields of engineering, electronics, energy technology, and electronics all utilize metal oxide nanoparticle powders. Metal Oxide Nanoparticles: Formation, Functional Properties, and Interfaces presents readers with the most relevant synthesis and formulation approaches for using metal oxide nanoparticles as functional materials. It covers common processing routes and the assessment of physical and chemical particle properties through comprehensive and complementary characterization methods. This book will serve as an introduction to nanoparticle formulation, their interface chemistry and functional properties at the nanoscale. It will also act as an in-depth resource, sharing detailed information on advanced approaches to the physical, chemical, surface, and interface characterization of metal oxide nanoparticle powders and dispersions. Addresses the application of metal oxide nanoparticles and its economic impact Examines particle synthesis, including the principles of selected bottom-up strategies Explores nanoparticle formulation—a selection of processing and application routes Discusses the significance of particle surfaces and interfaces on structure formation, stability and functional materials properties Covers metal oxide nanoparticle characterization at different length scales With this valuable resource, academic researchers, industrial chemists, and PhD students can all gain insight into the synthesis, properties, and applications of metal oxide nanoparticles.

When Antibiotics Fail

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Publisher : Council of Canadian Academies
ISBN 13 : 1926522753
Total Pages : 268 pages
Book Rating : 4.9/5 (265 download)

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Book Synopsis When Antibiotics Fail by : The Expert Panel on the Potential Socio-Economic Impacts of Antimicrobial Resistance in Canada

Download or read book When Antibiotics Fail written by The Expert Panel on the Potential Socio-Economic Impacts of Antimicrobial Resistance in Canada and published by Council of Canadian Academies. This book was released on 2019-11-12 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: When Antibiotics Fail examines the current impacts of AMR on our healthcare system, projects the future impact on Canada’s GDP, and looks at how widespread resistance will influence the day-to-day lives of Canadians. The report examines these issues through a One Health lens, recognizing the interconnected nature of AMR, from healthcare settings to the environment to the agriculture sector. It is the most comprehensive report to date on the economic impact of AMR in Canada.

Artificial Intelligence in Medical Imaging

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Publisher : Springer
ISBN 13 : 3319948784
Total Pages : 373 pages
Book Rating : 4.3/5 (199 download)

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Book Synopsis Artificial Intelligence in Medical Imaging by : Erik R. Ranschaert

Download or read book Artificial Intelligence in Medical Imaging written by Erik R. Ranschaert and published by Springer. This book was released on 2019-01-29 with total page 373 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a thorough overview of the ongoing evolution in the application of artificial intelligence (AI) within healthcare and radiology, enabling readers to gain a deeper insight into the technological background of AI and the impacts of new and emerging technologies on medical imaging. After an introduction on game changers in radiology, such as deep learning technology, the technological evolution of AI in computing science and medical image computing is described, with explanation of basic principles and the types and subtypes of AI. Subsequent sections address the use of imaging biomarkers, the development and validation of AI applications, and various aspects and issues relating to the growing role of big data in radiology. Diverse real-life clinical applications of AI are then outlined for different body parts, demonstrating their ability to add value to daily radiology practices. The concluding section focuses on the impact of AI on radiology and the implications for radiologists, for example with respect to training. Written by radiologists and IT professionals, the book will be of high value for radiologists, medical/clinical physicists, IT specialists, and imaging informatics professionals.

Guidelines on Hepatitis B and C Testing

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Publisher : World Health Organization
ISBN 13 : 9789241549981
Total Pages : 0 pages
Book Rating : 4.5/5 (499 download)

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Book Synopsis Guidelines on Hepatitis B and C Testing by : World Health Organization

Download or read book Guidelines on Hepatitis B and C Testing written by World Health Organization and published by World Health Organization. This book was released on 2017 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Testing and diagnosis of hepatitis B (HBV) and C (HCV) infection is the gateway for access to both prevention and treatment services, and is a crucial component of an effective response to the hepatitis epidemic. Early identification of persons with chronic HBV or HCV infection enables them to receive the necessary care and treatment to prevent or delay progression of liver disease. Testing also provides an opportunity to link people to interventions to reduce transmission, through counselling on risk behaviors and provision of prevention commodities (such as sterile needles and syringes) and hepatitis B vaccination. These are the first WHO guidelines on testing for chronic HBV and HCV infection and complement published guidance by WHO on the prevention, care and treatment of chronic hepatitis C and hepatitis B infection. These guidelines outline the public health approach to strengthening and expanding current testing practices for HBV and HCV, and are intended for use across age groups and populations.

Oral Medicine

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Publisher :
ISBN 13 :
Total Pages : 714 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Oral Medicine by : Lester William Burket

Download or read book Oral Medicine written by Lester William Burket and published by . This book was released on 1946 with total page 714 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Integrative Medicine and the Health of the Public

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Publisher : National Academies Press
ISBN 13 : 030914731X
Total Pages : 245 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Integrative Medicine and the Health of the Public by : Institute of Medicine

Download or read book Integrative Medicine and the Health of the Public written by Institute of Medicine and published by National Academies Press. This book was released on 2009-10-16 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: The last century witnessed dramatic changes in the practice of health care, and coming decades promise advances that were not imaginable even in the relatively recent past. Science and technology continue to offer new insights into disease pathways and treatments, as well as mechanisms of protecting health and preventing disease. Genomics and proteomics are bringing personalized risk assessment, prevention, and treatment options within reach; health information technology is expediting the collection and analysis of large amounts of data that can lead to improved care; and many disciplines are contributing to a broadening understanding of the complex interplay among biology, environment, behavior, and socioeconomic factors that shape health and wellness. On February 25 - 27, 2009, the Institute of Medicine (IOM) convened the Summit on Integrative Medicine and the Health of the Public in Washington, DC. The summit brought together more than 600 scientists, academic leaders, policy experts, health practitioners, advocates, and other participants from many disciplines to examine the practice of integrative medicine, its scientific basis, and its potential for improving health. This publication summarizes the background, presentations, and discussions that occurred during the summit.

Clinical Mycology

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Publisher :
ISBN 13 : 0195148096
Total Pages : 534 pages
Book Rating : 4.1/5 (951 download)

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Book Synopsis Clinical Mycology by : William E. Dismukes

Download or read book Clinical Mycology written by William E. Dismukes and published by . This book was released on 2003 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: Within the field of infectious diseases, medical mycology has experienced significant growth over the last decade. Invasive fungal infections have been increasing in many patient populations, including: those with AIDS; transplant recipients; and the elderly. As these populations grow, so does the diversity of fungal pathogens. Paralleling this development, there have been recent launches of several new antifungal drugs and therapies. Clinical Mycology offers a comprehensive review of this discipline. Organized by types of fungi, this volume covers microbiologic, epidemiologic and demographic aspects of fungal infections as well as diagnostic, clinical, therapeutic, and preventive approaches. Special patient populations are also detailed.

The Ecology of Mycobacteria

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Publisher : Springer Science & Business Media
ISBN 13 : 9401141029
Total Pages : 79 pages
Book Rating : 4.4/5 (11 download)

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Book Synopsis The Ecology of Mycobacteria by : J. Kazda

Download or read book The Ecology of Mycobacteria written by J. Kazda and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 79 pages. Available in PDF, EPUB and Kindle. Book excerpt: Detailed information dealing with the ecology of mycobacteria is derived from a variety of different scientific fields such as botany, biochemistry, genetics, immunology, microbiology and epidemiology. This is the first attempt to evaluate this information from an ecological point of view and to develop a strategy for the prevention of tuberculosis and other mycobacterioses based on the ecological behavior of mycobacteria, especially the potentially pathogenic species capable of either growth in the environment or provoking disease. Regarding the interests of the developing countries, special attention is paid to the ecology of Mycobacterium leprae and to the supporting effect of accompanying mycobacteria in its pathogenicity. On a more positive side, environmental mycobacteria play an important role in the ecology of moorland dragonflies. Such a book is needed for specialists working in the field of mycobacterial research, clinical laboratories, the public health service, food hygiene, the water industry and in general ecology.

Economic Evaluation in Clinical Trials

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Publisher : OUP Oxford
ISBN 13 : 0191508055
Total Pages : 265 pages
Book Rating : 4.1/5 (915 download)

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Book Synopsis Economic Evaluation in Clinical Trials by : Henry A. Glick

Download or read book Economic Evaluation in Clinical Trials written by Henry A. Glick and published by OUP Oxford. This book was released on 2014-10-02 with total page 265 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is becoming increasingly important to examine the relationship between the outcomes of a clinical trial and the costs of the medical therapy under study. The results of such analysis can affect reimbursement decisions for new medical technologies, drugs, devices or diagnostics. It can aid companies seeking to make claims about the cost-effectiveness of their product, as well as allowing early consideration of the economic value of therapies which may be important to improving initial adoption decisions. It is also vital for addressing the requirements of regulatory bodies. Economic Evaluation in Clinical Trials provides practical advice on how to conduct cost-effectiveness analyses in controlled trials of medical therapies. This new edition has been extensively rewritten and revised; topics discussed range from design issues such as the types of services that should be measured and price weights, to assessment of quality-adjusted life years. Illustrative materials, case histories and worked examples are included to encourage the reader to apply the methods discussed. These exercises are supported with datasets, programmes and solutions made available online.

Medical Education for the Future

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Publisher : Springer Science & Business Media
ISBN 13 : 9048196922
Total Pages : 293 pages
Book Rating : 4.0/5 (481 download)

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Book Synopsis Medical Education for the Future by : Alan Bleakley

Download or read book Medical Education for the Future written by Alan Bleakley and published by Springer Science & Business Media. This book was released on 2011-02-21 with total page 293 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of medical education is to benefit patients by improving the work of doctors. Patient centeredness is a centuries old concept in medicine, but there is still a long way to go before medical education can truly be said to be patient centered. Ensuring the centrality of the patient is a particular challenge during medical education, when students are still forming an identity as trainee doctors, and conservative attitudes towards medicine and education are common amongst medical teachers, making it hard to bring about improvements. How can teachers, policy makers, researchers and doctors bring about lasting change that will restore the patient to the heart of medical education? The authors, experienced medical educators, explore the role of the patient in medical education in terms of identity, power and location. Using innovative political, philosophical, cultural and literary critical frameworks that have previously never been applied so consistently to the field, the authors provide a fundamental reconceptualisation of medical teaching and learning, with an emphasis upon learning at the bedside and in the clinic. They offer a wealth of practical and conceptual insights into the three-way relationship between patients, students and teachers, setting out a radical and exciting approach to a medical education for the future. “The authors provide us with a masterful reconceptualization of medical education that challenges traditional notions about teaching and learning. The book critiques current practices and offers new approaches to medical education based upon sociocultural research and theory. This thought provoking narrative advances the case for reform and is a must read for anyone involved in medical education.” - David M. Irby, PhD, Vice Dean for Education, University of California, San Francisco School of Medicine; and co-author of Educating Physicians: A Call for Reform of Medical School and Residency "This book is a truly visionary contribution to the Flexner centenary. It is compulsory reading for the medical educationalist with a serious concern for the future - and for the welfare of patients and learners in the here and now." Professor Tim Dornan, University of Manchester Medical School and Maastricht University Graduate School of Health Professions Education.