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Author : Yichuan Zhao
Publisher : Springer Nature
ISBN 13 : 3031506901
Total Pages : 545 pages
Book Rating : 4.0/5 (315 download)
Download or read book Statistics in Precision Health written by Yichuan Zhao and published by Springer Nature. This book was released on with total page 545 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Yichuan Zhao
Publisher : Springer
ISBN 13 : 9783031506895
Total Pages : 0 pages
Book Rating : 4.5/5 (68 download)
Download or read book Statistics in Precision Health written by Yichuan Zhao and published by Springer. This book was released on 2024-07-12 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses statistical methods and their innovative applications in precision health. It serves as a valuable resource to foster the development of this growing field within the context of the big data era. The chapters cover a wide range of topics, including foundational principles, statistical theories, new procedures, advanced methods, and practical applications in precision medicine. Particular attention is devoted to the interplay between precision health, big data, and mobile health research, while also exploring precision medicine's role in clinical trials, electronic health record data analysis, survival analysis, and genomic studies. Targeted at data scientists, statisticians, graduate students, and researchers in academia, industry, and government, this book offers insights into the latest advances in personalized medicine using advanced statistical techniques.
Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309222222
Total Pages : 142 pages
Book Rating : 4.3/5 (92 download)
Download or read book Toward Precision Medicine written by National Research Council and published by National Academies Press. This book was released on 2012-01-16 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt: Motivated by the explosion of molecular data on humans-particularly data associated with individual patients-and the sense that there are large, as-yet-untapped opportunities to use this data to improve health outcomes, Toward Precision Medicine explores the feasibility and need for "a new taxonomy of human disease based on molecular biology" and develops a potential framework for creating one. The book says that a new data network that integrates emerging research on the molecular makeup of diseases with clinical data on individual patients could drive the development of a more accurate classification of diseases and ultimately enhance diagnosis and treatment. The "new taxonomy" that emerges would define diseases by their underlying molecular causes and other factors in addition to their traditional physical signs and symptoms. The book adds that the new data network could also improve biomedical research by enabling scientists to access patients' information during treatment while still protecting their rights. This would allow the marriage of molecular research and clinical data at the point of care, as opposed to research information continuing to reside primarily in academia. Toward Precision Medicine notes that moving toward individualized medicine requires that researchers and health care providers have access to very large sets of health- and disease-related data linked to individual patients. These data are also critical for developing the information commons, the knowledge network of disease, and ultimately the new taxonomy.
Author : Ernst R. Berndt
Publisher : University of Chicago Press
ISBN 13 : 022661123X
Total Pages : 361 pages
Book Rating : 4.2/5 (266 download)
Download or read book Economic Dimensions of Personalized and Precision Medicine written by Ernst R. Berndt and published by University of Chicago Press. This book was released on 2019-04-22 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: Personalized and precision medicine (PPM)—the targeting of therapies according to an individual’s genetic, environmental, or lifestyle characteristics—is becoming an increasingly important approach in health care treatment and prevention. The advancement of PPM is a challenge in traditional clinical, reimbursement, and regulatory landscapes because it is costly to develop and introduces a wide range of scientific, clinical, ethical, and socioeconomic issues. PPM raises a multitude of economic issues, including how information on accurate diagnosis and treatment success will be disseminated and who will bear the cost; changes to physician training to incorporate genetics, probability and statistics, and economic considerations; questions about whether the benefits of PPM will be confined to developed countries or will diffuse to emerging economies with less developed health care systems; the effects of patient heterogeneity on cost-effectiveness analysis; and opportunities for PPM’s growth beyond treatment of acute illness, such as prevention and reversal of chronic conditions. This volume explores the intersection of the scientific, clinical, and economic factors affecting the development of PPM, including its effects on the drug pipeline, on reimbursement of PPM diagnostics and treatments, and on funding of the requisite underlying research; and it examines recent empirical applications of PPM.
Author : Tarun Weeramanthri
Publisher : Frontiers Media SA
ISBN 13 : 2889455017
Total Pages : 149 pages
Book Rating : 4.8/5 (894 download)
Download or read book Precision Public Health written by Tarun Weeramanthri and published by Frontiers Media SA. This book was released on 2018-06-25 with total page 149 pages. Available in PDF, EPUB and Kindle. Book excerpt: Precision Public Health is a new and rapidly evolving field, that examines the application of new technologies to public health policy and practice. It draws on a broad range of disciplines including genomics, spatial data, data linkage, epidemiology, health informatics, big data, predictive analytics and communications. The hope is that these new technologies will strengthen preventive health, improve access to health care, and reach disadvantaged populations in all areas of the world. But what are the downsides and what are the risks, and how can we ensure the benefits flow to those population groups most in need, rather than simply to those individuals who can afford to pay? This is the first collection of theoretical frameworks, analyses of empirical data, and case studies to be assembled on this topic, published to stimulate debate and promote collaborative work.
Author : Anastasios A. Tsiatis
Publisher : CRC Press
ISBN 13 : 1498769780
Total Pages : 602 pages
Book Rating : 4.4/5 (987 download)
Download or read book Dynamic Treatment Regimes written by Anastasios A. Tsiatis and published by CRC Press. This book was released on 2019-12-19 with total page 602 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dynamic Treatment Regimes: Statistical Methods for Precision Medicine provides a comprehensive introduction to statistical methodology for the evaluation and discovery of dynamic treatment regimes from data. Researchers and graduate students in statistics, data science, and related quantitative disciplines with a background in probability and statistical inference and popular statistical modeling techniques will be prepared for further study of this rapidly evolving field. A dynamic treatment regime is a set of sequential decision rules, each corresponding to a key decision point in a disease or disorder process, where each rule takes as input patient information and returns the treatment option he or she should receive. Thus, a treatment regime formalizes how a clinician synthesizes patient information and selects treatments in practice. Treatment regimes are of obvious relevance to precision medicine, which involves tailoring treatment selection to patient characteristics in an evidence-based way. Of critical importance to precision medicine is estimation of an optimal treatment regime, one that, if used to select treatments for the patient population, would lead to the most beneficial outcome on average. Key methods for estimation of an optimal treatment regime from data are motivated and described in detail. A dedicated companion website presents full accounts of application of the methods using a comprehensive R package developed by the authors. The authors’ website www.dtr-book.com includes updates, corrections, new papers, and links to useful websites.
Author : Gabriella Pravettoni
Publisher : Springer Nature
ISBN 13 : 3030279944
Total Pages : 191 pages
Book Rating : 4.0/5 (32 download)
Download or read book P5 eHealth: An Agenda for the Health Technologies of the Future written by Gabriella Pravettoni and published by Springer Nature. This book was released on 2019-11-29 with total page 191 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access volume focuses on the development of a P5 eHealth, or better, a methodological resource for developing the health technologies of the future, based on patients’ personal characteristics and needs as the fundamental guidelines for design. It provides practical guidelines and evidence based examples on how to design, implement, use and elevate new technologies for healthcare to support the management of incurable, chronic conditions. The volume further discusses the criticalities of eHealth, why it is difficult to employ eHealth from an organizational point of view or why patients do not always accept the technology, and how eHealth interventions can be improved in the future. By dealing with the state-of-the-art in eHealth technologies, this volume is of great interest to researchers in the field of physical and mental healthcare, psychologists, stakeholders and policymakers as well as technology developers working in the healthcare sector.
Author : Michael Mahler
Publisher : Academic Press
ISBN 13 : 032385432X
Total Pages : 300 pages
Book Rating : 4.3/5 (238 download)
Download or read book Precision Medicine and Artificial Intelligence written by Michael Mahler and published by Academic Press. This book was released on 2021-03-12 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: Precision Medicine and Artificial Intelligence: The Perfect Fit for Autoimmunity covers background on artificial intelligence (AI), its link to precision medicine (PM), and examples of AI in healthcare, especially autoimmunity. The book highlights future perspectives and potential directions as AI has gained significant attention during the past decade. Autoimmune diseases are complex and heterogeneous conditions, but exciting new developments and implementation tactics surrounding automated systems have enabled the generation of large datasets, making autoimmunity an ideal target for AI and precision medicine. More and more diagnostic products utilize AI, which is also starting to be supported by regulatory agencies such as the Food and Drug Administration (FDA). Knowledge generation by leveraging large datasets including demographic, environmental, clinical and biomarker data has the potential to not only impact the diagnosis of patients, but also disease prediction, prognosis and treatment options. Allows the readers to gain an overview on precision medicine for autoimmune diseases leveraging AI solutions Provides background, milestone and examples of precision medicine Outlines the paradigm shift towards precision medicine driven by value-based systems Discusses future applications of precision medicine research using AI Other aspects covered in the book include regulatory insights, data analytics and visualization, types of biomarkers as well as the role of the patient in precision medicine
Author : Mukesh Verma
Publisher : Academic Press
ISBN 13 : 0128095024
Total Pages : 344 pages
Book Rating : 4.1/5 (28 download)
Download or read book Progress and Challenges in Precision Medicine written by Mukesh Verma and published by Academic Press. This book was released on 2016-12-22 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: Progress and Challenges in Precision Medicine presents an insightful overview to the myriad factors of personalized and precision medicine. The availability of the human genome, large amounts of data on individual genetic variations, environmental interactions, influence of lifestyle, and cutting-edge tools and technologies for big-data analysis have led to the age of personalized and precision medicine. Bringing together a global range of experts on precision medicine, this book collects previously scattered information into one concise volume which covers the most important developments so far in precision medicine and also suggests the most likely avenues for future development. The book includes clinical information, informatics, public policy implications, and information on case studies. It is a useful reference and background work for students, researchers, and clinicians working in the biomedical and medical fields, as well as policymakers in the health sciences. Provides an overview of the growing field of precision medicine Contains chapters from geographically diverse experts in their field Explores important aspects of precision medicine, including applications, ethics, and development
Author : Linda M. Collins
Publisher : Springer
ISBN 13 : 3319722069
Total Pages : 297 pages
Book Rating : 4.3/5 (197 download)
Download or read book Optimization of Behavioral, Biobehavioral, and Biomedical Interventions written by Linda M. Collins and published by Springer. This book was released on 2018-02-08 with total page 297 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a framework for development, optimization, and evaluation of behavioral, biobehavioral, and biomedical interventions. Behavioral, biobehavioral, and biomedical interventions are programs with the objective of improving and maintaining human health and well-being, broadly defined, in individuals, families, schools, organizations, or communities. These interventions may be aimed at, for example, preventing or treating disease, promoting physical and mental health, preventing violence, or improving academic achievement. This volume introduces the multiphase optimization strategy (MOST), pioneered at The Methodology Center at the Pennsylvania State University, as an alternative to the classical approach of relying solely on the randomized controlled trial (RCT). MOST borrows heavily from perspectives taken and approaches used in engineering, and also integrates concepts from statistics and behavioral science, including the RCT. As described in detail in this book, MOST consists of three phases: preparation, in which the conceptual model underlying the intervention is articulated; optimization, in which experimentation is used to gather the information necessary to identify the optimized intervention; and evaluation, in which the optimized intervention is evaluated in a standard RCT. Through numerous examples, the book demonstrates that MOST can be used to develop interventions that are more effective, efficient, economical, and scalable. Optimization of Behavioral, Biobehavioral, and Biomedical Interventions: The Multiphase Optimization Strategy is the first book to present a comprehensive introduction to MOST. It will be an essential resource for behavioral, biobehavioral, and biomedical scientists; statisticians, biostatisticians, and analysts working in epidemiology and public health; and graduate-level courses in development and evaluation of interventions.
Author : Anjani Chandra
Publisher :
ISBN 13 :
Total Pages : 24 pages
Book Rating : 4.3/5 (121 download)
Download or read book Infertility and Impaired Fecundity in the United States, 1982-2010 written by Anjani Chandra and published by . This book was released on 2013 with total page 24 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Hans-Peter Deigner
Publisher : Academic Press
ISBN 13 : 0128054336
Total Pages : 376 pages
Book Rating : 4.1/5 (28 download)
Download or read book Precision Medicine written by Hans-Peter Deigner and published by Academic Press. This book was released on 2018-02-15 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: Precision Medicine: Tools and Quantitative Approaches discusses precision and personalized medicine, two relevant topics that are revolutionizing diagnostics and treatment, while also providing a shift toward prevention. The book covers the most relevant features and explanations underlying developments in the field. A timely review on prerequisites, causes and consequences is given. Unique to this book is a combined view on technical and data analysis aspects that is mandatory for obtaining and interpreting results. This book is a valuable source for researchers in medical and life sciences, physicians and students with an interest in this emerging field of precision medicine. Provides technological aspects in precision medicine with aspects of modern statistical and bioinformatics models and methods Brings timely reviews on status and chances in precision medicine and associated aspects of data analysis, statistics and data interpretation Encompasses easy access to relevant approaches, interactions and original literature
Author : Mark Chang
Publisher : CRC Press
ISBN 13 : 1000767302
Total Pages : 235 pages
Book Rating : 4.0/5 (7 download)
Download or read book Artificial Intelligence for Drug Development, Precision Medicine, and Healthcare written by Mark Chang and published by CRC Press. This book was released on 2020-05-12 with total page 235 pages. Available in PDF, EPUB and Kindle. Book excerpt: Artificial Intelligence for Drug Development, Precision Medicine, and Healthcare covers exciting developments at the intersection of computer science and statistics. While much of machine-learning is statistics-based, achievements in deep learning for image and language processing rely on computer science’s use of big data. Aimed at those with a statistical background who want to use their strengths in pursuing AI research, the book: · Covers broad AI topics in drug development, precision medicine, and healthcare. · Elaborates on supervised, unsupervised, reinforcement, and evolutionary learning methods. · Introduces the similarity principle and related AI methods for both big and small data problems. · Offers a balance of statistical and algorithm-based approaches to AI. · Provides examples and real-world applications with hands-on R code. · Suggests the path forward for AI in medicine and artificial general intelligence. As well as covering the history of AI and the innovative ideas, methodologies and software implementation of the field, the book offers a comprehensive review of AI applications in medical sciences. In addition, readers will benefit from hands on exercises, with included R code.
Author : Pei-Yun Sabrina Hsueh
Publisher : Springer Nature
ISBN 13 : 3031076966
Total Pages : 580 pages
Book Rating : 4.0/5 (31 download)
Download or read book Personal Health Informatics written by Pei-Yun Sabrina Hsueh and published by Springer Nature. This book was released on 2022-11-22 with total page 580 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book clarifies consumer and personal health informatics and their relevance to precision medicine and healthcare applications. Personal Health Informatics covers a broad definition of this emerging field, with individuals not simply consuming health but as active participants, researchers and designers in the healthcare ecosystem. The world of health informatics is constantly changing given the ever-increasing variety and volume of health data, care delivery models that shift from fee-for-service to value-based care, new entrants in the ecosystem and the evolving regulatory decision landscape. These changes have increased the importance of the role of patients in research studies for understanding work processes and activities, and the design and implementation of health information systems. Therefore, personal health informatics now provide research tools and protocols to engage within individual contexts when developing solutions, which can improve clinical practice, patient engagement and public health. Personal Health Informatics offers a snapshot of this emerging field, supported by the methodological, practical, legal and ethical perspectives of researchers and practitioners. In addition to being a research reader, this book provides pragmatic insights for practitioners in designing, implementing and evaluating personal health informatics in healthcare settings. It represents an excellent reader for students in all clinical disciplines and biomedical and health informatics to learn from the case studies provided in this emerging field.
Author : Lloyd Minor
Publisher : John Wiley & Sons
ISBN 13 : 1119672686
Total Pages : 288 pages
Book Rating : 4.1/5 (196 download)
Download or read book Discovering Precision Health written by Lloyd Minor and published by John Wiley & Sons. This book was released on 2020-01-23 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Today we are on the brink of a much-needed transformative moment for health care. The U.S. health care system is designed to be reactive instead of preventive. The result is diagnoses that are too late and outcomes that are far worse than our level of spending should deliver. In recent years, U.S. life expectancy has been declining. Fundamental to realizing better health, and a more effective health care system, is advancing the disruptive thinking that has spawned innovation in Silicon Valley and throughout the world. That's exactly what Stanford Medicine has done by proposing a new vision for health and health care. In Discovering Precision Health, Lloyd Minor and Matthew Rees describe a holistic approach that will set health care on the right track: keep people healthy by preventing disease before it starts and personalize the treatment of individuals precisely, based on their specific profile. With descriptions of the pioneering work undertaken at Stanford Medicine, complemented by fascinating case studies of innovations from entities including the Chan Zuckerberg Biohub, GRAIL, and Impossible Foods, Minor and Rees present a dynamic vision for the future of individual health and health care. You'll see how tools from smartphone technology to genome sequencing to routine blood tests are helping avert illness and promote health. And you'll learn about the promising progress already underway in bringing greater precision to the process of predicting, preventing, and treating a range of conditions, including allergies, mental illness, preterm birth, cancer, stroke, and autism. The book highlights how biomedical advances are dramatically improving our ability to treat and cure complex diseases, while emphasizing the need to devote more attention to social, behavioral, and environmental factors that are often the primary determinants of health. The authors explore thought-provoking topics including: The unlikely role of Google Glass in treating autism How gene editing can advance precision in treating disease What medicine can learn from aviation liHow digital tools can contribute to health and innovation Discovering Precision Health showcases entirely new ways of thinking about health and health care and can help empower us to lead healthier lives.
Author : James M. Rehg
Publisher : Springer
ISBN 13 : 331951394X
Total Pages : 542 pages
Book Rating : 4.3/5 (195 download)
Download or read book Mobile Health written by James M. Rehg and published by Springer. This book was released on 2017-07-12 with total page 542 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a comprehensive introduction to mHealth technology and is accessible to technology-oriented researchers and practitioners with backgrounds in computer science, engineering, statistics, and applied mathematics. The contributing authors include leading researchers and practitioners in the mHealth field. The book offers an in-depth exploration of the three key elements of mHealth technology: the development of on-body sensors that can identify key health-related behaviors (sensors to markers), the use of analytic methods to predict current and future states of health and disease (markers to predictors), and the development of mobile interventions which can improve health outcomes (predictors to interventions). Chapters are organized into sections, with the first section devoted to mHealth applications, followed by three sections devoted to the above three key technology areas. Each chapter can be read independently, but the organization of the entire book provides a logical flow from the design of on-body sensing technology, through the analysis of time-varying sensor data, to interactions with a user which create opportunities to improve health outcomes. This volume is a valuable resource to spur the development of this growing field, and ideally suited for use as a textbook in an mHealth course.
Author : Debmalya Barh
Publisher : Academic Press
ISBN 13 : 0128173386
Total Pages : 544 pages
Book Rating : 4.1/5 (281 download)
Download or read book Artificial Intelligence in Precision Health written by Debmalya Barh and published by Academic Press. This book was released on 2020-03-04 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: Artificial Intelligence in Precision Health: From Concept to Applications provides a readily available resource to understand artificial intelligence and its real time applications in precision medicine in practice. Written by experts from different countries and with diverse background, the content encompasses accessible knowledge easily understandable for non-specialists in computer sciences. The book discusses topics such as cognitive computing and emotional intelligence, big data analysis, clinical decision support systems, deep learning, personal omics, digital health, predictive models, prediction of epidemics, drug discovery, precision nutrition and fitness. Additionally, there is a section dedicated to discuss and analyze AI products related to precision healthcare already available. This book is a valuable source for clinicians, healthcare workers, and researchers from diverse areas of biomedical field who may or may not have computational background and want to learn more about the innovative field of artificial intelligence for precision health. Provides computational approaches used in artificial intelligence easily understandable for non-computer specialists Gives know-how and real successful cases of artificial intelligence approaches in predictive models, modeling disease physiology, and public health surveillance Discusses the applicability of AI on multiple areas, such as drug discovery, clinical trials, radiology, surgery, patient care and clinical decision support
