Statistical Studies

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An Introduction to Statistical Genetic Data Analysis

Author : Melinda C. Mills
Publisher : MIT Press
ISBN 13 : 0262357445
Total Pages : 433 pages
Book Rating : 4.2/5 (623 download)

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Book Synopsis An Introduction to Statistical Genetic Data Analysis by : Melinda C. Mills

Download or read book An Introduction to Statistical Genetic Data Analysis written by Melinda C. Mills and published by MIT Press. This book was released on 2020-02-18 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive introduction to modern applied statistical genetic data analysis, accessible to those without a background in molecular biology or genetics. Human genetic research is now relevant beyond biology, epidemiology, and the medical sciences, with applications in such fields as psychology, psychiatry, statistics, demography, sociology, and economics. With advances in computing power, the availability of data, and new techniques, it is now possible to integrate large-scale molecular genetic information into research across a broad range of topics. This book offers the first comprehensive introduction to modern applied statistical genetic data analysis that covers theory, data preparation, and analysis of molecular genetic data, with hands-on computer exercises. It is accessible to students and researchers in any empirically oriented medical, biological, or social science discipline; a background in molecular biology or genetics is not required. The book first provides foundations for statistical genetic data analysis, including a survey of fundamental concepts, primers on statistics and human evolution, and an introduction to polygenic scores. It then covers the practicalities of working with genetic data, discussing such topics as analytical challenges and data management. Finally, the book presents applications and advanced topics, including polygenic score and gene-environment interaction applications, Mendelian Randomization and instrumental variables, and ethical issues. The software and data used in the book are freely available and can be found on the book's website.

The Analysis of Case-control Studies

Author : Norman E. Breslow
Publisher :
ISBN 13 :
Total Pages : 352 pages
Book Rating : 4.3/5 (223 download)

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Book Synopsis The Analysis of Case-control Studies by : Norman E. Breslow

Download or read book The Analysis of Case-control Studies written by Norman E. Breslow and published by . This book was released on 1980 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Study Design and Statistical Analysis

Author : Mitchell Katz
Publisher : Cambridge University Press
ISBN 13 : 1139643738
Total Pages : 229 pages
Book Rating : 4.1/5 (396 download)

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Book Synopsis Study Design and Statistical Analysis by : Mitchell Katz

Download or read book Study Design and Statistical Analysis written by Mitchell Katz and published by Cambridge University Press. This book was released on 2006-06-22 with total page 229 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book takes the reader through the entire research process: choosing a question, designing a study, collecting the data, using univariate, bivariate and multivariable analysis, and publishing the results. It does so by using plain language rather than complex derivations and mathematical formulae. It focuses on the nuts and bolts of performing research by asking and answering the most basic questions about doing research studies. Making good use of numerous tables, graphs and tips, this book helps to demystify the process. A generous number of up-to-date examples from the clinical literature give an illustrated and practical account of how to use multivariable analysis.

Quantitative and Statistical Research Methods

Author : William E. Martin
Publisher : John Wiley & Sons
ISBN 13 : 111823457X
Total Pages : 498 pages
Book Rating : 4.1/5 (182 download)

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Book Synopsis Quantitative and Statistical Research Methods by : William E. Martin

Download or read book Quantitative and Statistical Research Methods written by William E. Martin and published by John Wiley & Sons. This book was released on 2012-07-09 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt: Quantitative and Statistical Research Methods This user-friendly textbook teaches students to understand and apply procedural steps in completing quantitative studies. It explains statistics while progressing through the steps of the hypothesis-testing process from hypothesis to results. The research problems used in the book reflect statistical applications related to interesting and important topics. In addition, the book provides a Research Analysis and Interpretation Guide to help students analyze research articles. Designed as a hands-on resource, each chapter covers a single research problem and offers directions for implementing the research method from start to finish. Readers will learn how to: Pinpoint research questions and hypotheses Identify, classify, and operationally define the study variables Choose appropriate research designs Conduct power analysis Select an appropriate statistic for the problem Use a data set Conduct data screening and analyses using SPSS Interpret the statistics Write the results related to the problem Quantitative and Statistical Research Methods allows students to immediately, independently, and successfully apply quantitative methods to their own research projects.

Statistical Analysis Quick Reference Guidebook

Author : Alan C. Elliott
Publisher : SAGE
ISBN 13 : 9781412925600
Total Pages : 280 pages
Book Rating : 4.9/5 (256 download)

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Book Synopsis Statistical Analysis Quick Reference Guidebook by : Alan C. Elliott

Download or read book Statistical Analysis Quick Reference Guidebook written by Alan C. Elliott and published by SAGE. This book was released on 2007 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: A practical `cut to the chase′ handbook that quickly explains the when, where, and how of statistical data analysis as it is used for real-world decision-making in a wide variety of disciplines. In this one-stop reference, the authors provide succinct guidelines for performing an analysis, avoiding pitfalls, interpreting results and reporting outcomes.

Statistical Methods in Water Resources

Author : D.R. Helsel
Publisher : Elsevier
ISBN 13 : 0080875084
Total Pages : 539 pages
Book Rating : 4.0/5 (88 download)

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Book Synopsis Statistical Methods in Water Resources by : D.R. Helsel

Download or read book Statistical Methods in Water Resources written by D.R. Helsel and published by Elsevier. This book was released on 1993-03-03 with total page 539 pages. Available in PDF, EPUB and Kindle. Book excerpt: Data on water quality and other environmental issues are being collected at an ever-increasing rate. In the past, however, the techniques used by scientists to interpret this data have not progressed as quickly. This is a book of modern statistical methods for analysis of practical problems in water quality and water resources.The last fifteen years have seen major advances in the fields of exploratory data analysis (EDA) and robust statistical methods. The 'real-life' characteristics of environmental data tend to drive analysis towards the use of these methods. These advances are presented in a practical and relevant format. Alternate methods are compared, highlighting the strengths and weaknesses of each as applied to environmental data. Techniques for trend analysis and dealing with water below the detection limit are topics covered, which are of great interest to consultants in water-quality and hydrology, scientists in state, provincial and federal water resources, and geological survey agencies.The practising water resources scientist will find the worked examples using actual field data from case studies of environmental problems, of real value. Exercises at the end of each chapter enable the mechanics of the methodological process to be fully understood, with data sets included on diskette for easy use. The result is a book that is both up-to-date and immediately relevant to ongoing work in the environmental and water sciences.

How Many Subjects?

Author : Helena Chmura Kraemer
Publisher : SAGE
ISBN 13 : 9780803929494
Total Pages : 128 pages
Book Rating : 4.9/5 (294 download)

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Book Synopsis How Many Subjects? by : Helena Chmura Kraemer

Download or read book How Many Subjects? written by Helena Chmura Kraemer and published by SAGE. This book was released on 1987-09 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: How Many Subjects? is a practical guide to sample size calculations and general principles of cost-effective research. It introduces a simple technique of statistical power analysis which allows researchers to compute approximate sample sizes and power for a wide variety of research designs. Because the same technique is used with only slight modifications for different statistical tests, researchers can easily compare the sample sizes required by different designs and tests to make cost-effective decisions in planning a study. These comparisons, emphasized throughout the book, demonstrate important principles of design, measurement and analysis that are rarely discussed in courses or textbooks.

Statistical Analysis of Climate Extremes

Author : Manfred Mudelsee
Publisher : Cambridge University Press
ISBN 13 : 1107033187
Total Pages : 213 pages
Book Rating : 4.1/5 (7 download)

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Book Synopsis Statistical Analysis of Climate Extremes by : Manfred Mudelsee

Download or read book Statistical Analysis of Climate Extremes written by Manfred Mudelsee and published by Cambridge University Press. This book was released on 2020 with total page 213 pages. Available in PDF, EPUB and Kindle. Book excerpt: The risks posed by climate change and its effect on climate extremes are an increasingly pressing societal problem. This book provides an accessible overview of the statistical analysis methods which can be used to investigate climate extremes and analyse potential risk. The statistical analysis methods are illustrated with case studies on extremes in the three major climate variables: temperature, precipitation, and wind speed. The book also provides datasets and access to appropriate analysis software, allowing the reader to replicate the case study calculations. Providing the necessary tools to analyse climate risk, this book is invaluable for students and researchers working in the climate sciences, as well as risk analysts interested in climate extremes.

Handbook of Statistical Methods for Case-Control Studies

Author : Ørnulf Borgan
Publisher : CRC Press
ISBN 13 : 1498768598
Total Pages : 536 pages
Book Rating : 4.4/5 (987 download)

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Book Synopsis Handbook of Statistical Methods for Case-Control Studies by : Ørnulf Borgan

Download or read book Handbook of Statistical Methods for Case-Control Studies written by Ørnulf Borgan and published by CRC Press. This book was released on 2018-06-27 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Statistical Methods for Case-Control Studies is written by leading researchers in the field. It provides an in-depth treatment of up-to-date and currently developing statistical methods for the design and analysis of case-control studies, as well as a review of classical principles and methods. The handbook is designed to serve as a reference text for biostatisticians and quantitatively-oriented epidemiologists who are working on the design and analysis of case-control studies or on related statistical methods research. Though not specifically intended as a textbook, it may also be used as a backup reference text for graduate level courses. Book Sections Classical designs and causal inference, measurement error, power, and small-sample inference Designs that use full-cohort information Time-to-event data Genetic epidemiology About the Editors Ørnulf Borgan is Professor of Statistics, University of Oslo. His book with Andersen, Gill and Keiding on counting processes in survival analysis is a world classic. Norman E. Breslow was, at the time of his death, Professor Emeritus in Biostatistics, University of Washington. For decades, his book with Nick Day has been the authoritative text on case-control methodology. Nilanjan Chatterjee is Bloomberg Distinguished Professor, Johns Hopkins University. He leads a broad research program in statistical methods for modern large scale biomedical studies. Mitchell H. Gail is a Senior Investigator at the National Cancer Institute. His research includes modeling absolute risk of disease, intervention trials, and statistical methods for epidemiology. Alastair Scott was, at the time of his death, Professor Emeritus of Statistics, University of Auckland. He was a major contributor to using survey sampling methods for analyzing case-control data. Chris J. Wild is Professor of Statistics, University of Auckland. His research includes nonlinear regression and methods for fitting models to response-selective data.

Intermediate Statistical Investigations

Author : Nathan Tintle
Publisher : John Wiley & Sons
ISBN 13 : 1119634520
Total Pages : 608 pages
Book Rating : 4.1/5 (196 download)

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Book Synopsis Intermediate Statistical Investigations by : Nathan Tintle

Download or read book Intermediate Statistical Investigations written by Nathan Tintle and published by John Wiley & Sons. This book was released on 2020-09-09 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt: Intermediate Statistical Investigations provides a unified framework for explaining variation across study designs and variable types, helping students increase their statistical literacy and appreciate the indispensable role of statistics in scientific research. Requiring only a single introductory statistics course as a prerequisite, the program uses the immersive, simulation-based inference approach for which the author team is known.Students engage with various aspects of data collection and analysis using real examples and clear explanations designed to strengthen multivariable understanding and reinforce first-course concepts. Each chapter contains in-depth exercises which follow a consistent six-step statistical exploration and investigation method (ask a research question, design a study, explore the data, draw inferences, formulate conclusions, and look back and ahead) enabling students to assess a variety of concepts in a single assignment. Challenging questions based on research articles strengthen critical reading skills, fully worked examples demonstrate essential concepts and methods, and engaging visualizations illustrate key themes of explained variation. End-of-chapter investigations use real data from popular culture and published research studies in a variety of disciplines, exposing students to various applications of statistics in the real world. Throughout the text, user-friendly Rossman Chance web applets allow students to conduct the simulations and analyses covered in the book.

Statistical Analysis of Ecotoxicity Studies

Author : John W. Green
Publisher : John Wiley & Sons
ISBN 13 : 1119088348
Total Pages : 416 pages
Book Rating : 4.1/5 (19 download)

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Book Synopsis Statistical Analysis of Ecotoxicity Studies by : John W. Green

Download or read book Statistical Analysis of Ecotoxicity Studies written by John W. Green and published by John Wiley & Sons. This book was released on 2018-08-14 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: A guide to the issues relevant to the design, analysis, and interpretation of toxicity studies that examine chemicals for use in the environment Statistical Analysis of Ecotoxicity Studies offers a guide to the design, analysis, and interpretation of a range of experiments that are used to assess the toxicity of chemicals. While the book highlights ecotoxicity studies, the methods presented are applicable to the broad range of toxicity studies. The text contains myriad datasets (from laboratory and field research) that clearly illustrate the book's topics. The datasets reveal the techniques, pitfalls, and precautions derived from these studies. The text includes information on recently developed methods for the analysis of severity scores and other ordered responses, as well as extensive power studies of competing tests and computer simulation studies of regression models that offer an understanding of the sensitivity (or lack thereof) of various methods and the quality of parameter estimates from regression models. The authors also discuss the regulatory process indicating how test guidelines are developed and review the statistical methodology in current or pending OECD and USEPA ecotoxicity guidelines. This important guide: Offers the information needed for the design and analysis to a wide array of ecotoxicity experiments and to the development of international test guidelines used to assess the toxicity of chemicals Contains a thorough examination of the statistical issues that arise in toxicity studies, especially ecotoxicity Includes an introduction to toxicity experiments and statistical analysis basics Includes programs in R and excel Covers the analysis of continuous and Quantal data, analysis of data as well as Regulatory Issues Presents additional topics (Mesocosm and Microplate experiments, mixtures of chemicals, benchmark dose models, and limit tests) as well as software Written for directors, scientists, regulators, and technicians, Statistical Analysis of Ecotoxicity Studies provides a sound understanding of the technical and practical issues in designing, analyzing, and interpreting toxicity studies to support or challenge chemicals for use in the environment.

Small Clinical Trials

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309171148
Total Pages : 221 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Small Clinical Trials by : Institute of Medicine

Download or read book Small Clinical Trials written by Institute of Medicine and published by National Academies Press. This book was released on 2001-01-01 with total page 221 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical trials are used to elucidate the most appropriate preventive, diagnostic, or treatment options for individuals with a given medical condition. Perhaps the most essential feature of a clinical trial is that it aims to use results based on a limited sample of research participants to see if the intervention is safe and effective or if it is comparable to a comparison treatment. Sample size is a crucial component of any clinical trial. A trial with a small number of research participants is more prone to variability and carries a considerable risk of failing to demonstrate the effectiveness of a given intervention when one really is present. This may occur in phase I (safety and pharmacologic profiles), II (pilot efficacy evaluation), and III (extensive assessment of safety and efficacy) trials. Although phase I and II studies may have smaller sample sizes, they usually have adequate statistical power, which is the committee's definition of a "large" trial. Sometimes a trial with eight participants may have adequate statistical power, statistical power being the probability of rejecting the null hypothesis when the hypothesis is false. Small Clinical Trials assesses the current methodologies and the appropriate situations for the conduct of clinical trials with small sample sizes. This report assesses the published literature on various strategies such as (1) meta-analysis to combine disparate information from several studies including Bayesian techniques as in the confidence profile method and (2) other alternatives such as assessing therapeutic results in a single treated population (e.g., astronauts) by sequentially measuring whether the intervention is falling above or below a preestablished probability outcome range and meeting predesigned specifications as opposed to incremental improvement.

Statistical Analysis in Climate Research

Author : Hans von Storch
Publisher : Cambridge University Press
ISBN 13 : 1139425099
Total Pages : 979 pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis Statistical Analysis in Climate Research by : Hans von Storch

Download or read book Statistical Analysis in Climate Research written by Hans von Storch and published by Cambridge University Press. This book was released on 2002-02-21 with total page 979 pages. Available in PDF, EPUB and Kindle. Book excerpt: Climatology is, to a large degree, the study of the statistics of our climate. The powerful tools of mathematical statistics therefore find wide application in climatological research. The purpose of this book is to help the climatologist understand the basic precepts of the statistician's art and to provide some of the background needed to apply statistical methodology correctly and usefully. The book is self contained: introductory material, standard advanced techniques, and the specialised techniques used specifically by climatologists are all contained within this one source. There are a wealth of real-world examples drawn from the climate literature to demonstrate the need, power and pitfalls of statistical analysis in climate research. Suitable for graduate courses on statistics for climatic, atmospheric and oceanic science, this book will also be valuable as a reference source for researchers in climatology, meteorology, atmospheric science, and oceanography.

Statistical Case Studies

Author : Roxy Peck
Publisher : SIAM
ISBN 13 : 0898714133
Total Pages : 308 pages
Book Rating : 4.8/5 (987 download)

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Book Synopsis Statistical Case Studies by : Roxy Peck

Download or read book Statistical Case Studies written by Roxy Peck and published by SIAM. This book was released on 1998-01-01 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains 20 case studies that use actual data sets that have not been simplified for classroom use.

Practical Statistics

Author : David Kremelberg
Publisher : SAGE Publications
ISBN 13 : 150631791X
Total Pages : 529 pages
Book Rating : 4.5/5 (63 download)

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Book Synopsis Practical Statistics by : David Kremelberg

Download or read book Practical Statistics written by David Kremelberg and published by SAGE Publications. This book was released on 2010-03-18 with total page 529 pages. Available in PDF, EPUB and Kindle. Book excerpt: Making statistics—and statistical software—accessible and rewarding This book provides readers with step-by-step guidance on running a wide variety of statistical analyses in IBM® SPSS® Statistics, Stata, and other programs. Author David Kremelberg begins his user-friendly text by covering charts and graphs through regression, time-series analysis, and factor analysis. He provides a background of the method, then explains how to run these tests in IBM SPSS and Stata. He then progresses to more advanced kinds of statistics such as HLM and SEM, where he describes the tests and explains how to run these tests in their appropriate software including HLM and AMOS. This is an invaluable guide for upper-level undergraduate and graduate students across the social and behavioral sciences who need assistance in understanding the various statistical packages.

Handbook of Statistical Analysis and Data Mining Applications

Author : Ken Yale
Publisher : Elsevier
ISBN 13 : 0124166458
Total Pages : 824 pages
Book Rating : 4.1/5 (241 download)

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Book Synopsis Handbook of Statistical Analysis and Data Mining Applications by : Ken Yale

Download or read book Handbook of Statistical Analysis and Data Mining Applications written by Ken Yale and published by Elsevier. This book was released on 2017-11-09 with total page 824 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Statistical Analysis and Data Mining Applications, Second Edition, is a comprehensive professional reference book that guides business analysts, scientists, engineers and researchers, both academic and industrial, through all stages of data analysis, model building and implementation. The handbook helps users discern technical and business problems, understand the strengths and weaknesses of modern data mining algorithms and employ the right statistical methods for practical application. This book is an ideal reference for users who want to address massive and complex datasets with novel statistical approaches and be able to objectively evaluate analyses and solutions. It has clear, intuitive explanations of the principles and tools for solving problems using modern analytic techniques and discusses their application to real problems in ways accessible and beneficial to practitioners across several areas—from science and engineering, to medicine, academia and commerce. - Includes input by practitioners for practitioners - Includes tutorials in numerous fields of study that provide step-by-step instruction on how to use supplied tools to build models - Contains practical advice from successful real-world implementations - Brings together, in a single resource, all the information a beginner needs to understand the tools and issues in data mining to build successful data mining solutions - Features clear, intuitive explanations of novel analytical tools and techniques, and their practical applications

Statistical Methods

Author : Rudolf J. Freund
Publisher : Elsevier
ISBN 13 : 0080498221
Total Pages : 694 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Statistical Methods by : Rudolf J. Freund

Download or read book Statistical Methods written by Rudolf J. Freund and published by Elsevier. This book was released on 2003-01-07 with total page 694 pages. Available in PDF, EPUB and Kindle. Book excerpt: This broad text provides a complete overview of most standard statistical methods, including multiple regression, analysis of variance, experimental design, and sampling techniques. Assuming a background of only two years of high school algebra, this book teaches intelligent data analysis and covers the principles of good data collection. * Provides a complete discussion of analysis of data including estimation, diagnostics, and remedial actions * Examples contain graphical illustration for ease of interpretation * Intended for use with almost any statistical software * Examples are worked to a logical conclusion, including interpretation of results * A complete Instructor's Manual is available to adopters