Spirochetes and Immune Evasion: Infection, Persistence and Clearance

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Publisher : Frontiers Media SA
ISBN 13 : 2889637301
Total Pages : 201 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Spirochetes and Immune Evasion: Infection, Persistence and Clearance by : Maria Gomes-Solecki

Download or read book Spirochetes and Immune Evasion: Infection, Persistence and Clearance written by Maria Gomes-Solecki and published by Frontiers Media SA. This book was released on 2020-06-04 with total page 201 pages. Available in PDF, EPUB and Kindle. Book excerpt: The interface between spirochetes and the immune response is of significant importance to their pathogenesis and persistence. Evasion from the immune system leads to infections that present as Leptospirosis, Syphilis, Lyme Disease and Relapsing Fever and may lead to putative persistence and latency. Understanding the mechanisms involved in immune evasion will shed light not only on the hostpathogen factors involved in the process but also on how resistance to infection leads to protection. Broad examples include spirochetal interaction with the immune system, spirochetal molecules involved in immune evasion and in immune activation, innate immune responses in the skin and other compartments, factors involved in spirochetal adhesion to the extracellular matrix, interaction of spirochetes with antigen presenting cells, in vitro, ex vivo or in vivo, spirochetal lipoproteins and immunity. Specific examples include innate immunity to pathogenic spirochetes (T. pallidum, B. burgdorferi and Leptospira spp.), invasion and pathogenesis by L. interrogans, subversion and suppression of B cell responses by B. burgdorferi, role of antibody in clearance versus persistence of relapsing fever Borreliae, evasion of the complement system by B. burgdorferi, immune suppression by Ixodes tick saliva for effective transmission, adhesins and enzymes involved in dissemination of T. pallidum, spirochetal variable surface proteins in immune evasion, intravital imaging of pathogenic spirochetes (Borreliae and Leptospira) in host tissues, spirochete-host surface interactions. Additional specific examples for B. burgdorferi include novel approaches to control infection within the vector and/or in mammal; tick innate immune defenses and interaction of Ixodes scapularis salivary immunomodulatory molecules with human immune cells, tick-innate immune defenses (from the perspective of the tick midgut), mouse models of infection and genetic basis for pathogenicity, diverse roles of outer surface protein C. Additional specific examples for Leptospirosis include animal models of acute, sub-lethal and persistent infection; neutrophils and innate immune response; Toll-like receptor mediated B cell responses; markers of endothelial cell activation for disease severity in human leptospirosis, corticosteroid treatment of advanced human leptospirosis, and urinary biomarkers of chronic Leptospirosis.

The Pathogenic Spirochetes: strategies for evasion of host immunity and persistence

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1461454042
Total Pages : 273 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis The Pathogenic Spirochetes: strategies for evasion of host immunity and persistence by : Monica E. Embers

Download or read book The Pathogenic Spirochetes: strategies for evasion of host immunity and persistence written by Monica E. Embers and published by Springer Science & Business Media. This book was released on 2012-12-09 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: ​This book explores the many mechanisms by which the most prevalent Spirochetal pathogens persist in a healthy immune-competent host. Among them are the direct and indirect suppression of host immune signals, phase and antigenic variation, escaping recognition by host complement proteins, and seclusion into immune privileged sites. We also explore antibiotic therapy for control of infection, a baffling topic that lends itself to exalted interpretation.

Janeway's Immunobiology

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Publisher : Garland Science
ISBN 13 : 9780815344575
Total Pages : pages
Book Rating : 4.3/5 (445 download)

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Book Synopsis Janeway's Immunobiology by : Kenneth Murphy

Download or read book Janeway's Immunobiology written by Kenneth Murphy and published by Garland Science. This book was released on 2010-06-22 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.

Critical Needs and Gaps in Understanding Prevention, Amelioration, and Resolution of Lyme and Other Tick-Borne Diseases

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Publisher : National Academies Press
ISBN 13 : 0309211093
Total Pages : 560 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis Critical Needs and Gaps in Understanding Prevention, Amelioration, and Resolution of Lyme and Other Tick-Borne Diseases by : Institute of Medicine

Download or read book Critical Needs and Gaps in Understanding Prevention, Amelioration, and Resolution of Lyme and Other Tick-Borne Diseases written by Institute of Medicine and published by National Academies Press. This book was released on 2011-07-01 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: A single tick bite can have debilitating consequences. Lyme disease is the most common disease carried by ticks in the United States, and the number of those afflicted is growing steadily. If left untreated, the diseases carried by ticks-known as tick-borne diseases-can cause severe pain, fatigue, neurological problems, and other serious health problems. The Institute of Medicine held a workshop October 11-12, 2010, to examine the state of the science in Lyme disease and other tick-borne diseases.

The Immune Response

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Publisher : Academic Press
ISBN 13 : 0080534481
Total Pages : 1217 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis The Immune Response by : Tak W. Mak

Download or read book The Immune Response written by Tak W. Mak and published by Academic Press. This book was released on 2005-11-11 with total page 1217 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Immune Response is a unique reference work covering the basic and clinical principles of immunology in a modern and comprehensive fashion. Written in an engaging conversational style, the book conveys the broad scope and fascinating appeal of immunology. The book is beautifully illustrated with superb figures as well as many full color plates. This extraordinary work will be an invaluable resource for lecturers and graduate students in immunology, as well as a vital reference for research scientists and clinicians studying related areas in the life and medical sciences. Current and thorough 30 chapter reference reviewed by luminaries in the field Unique ‘single voice' ensures consistency of definitions and concepts Comprehensive and elegant illustrations bring key concepts to life Provides historical context to allow fuller understanding of key issues Introductory chapters 1-4 serve as an ‘Immunology Primer' before topics are discussed in more detail

Leptospira and Leptospirosis

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Publisher : Springer
ISBN 13 : 3662450593
Total Pages : 295 pages
Book Rating : 4.6/5 (624 download)

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Book Synopsis Leptospira and Leptospirosis by : Ben Adler

Download or read book Leptospira and Leptospirosis written by Ben Adler and published by Springer. This book was released on 2014-11-11 with total page 295 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume covers all aspects of infection by pathogenic Leptospira species, the causative agents of the world’s most widespread zoonosis. Topics include aspects of human and animal leptospirosis as well as detailed analyses of our current knowledge of leptospiral structure and physiology, epidemiology, pathogenesis, genomics, immunity and vaccines. Updates are presented on leptospiral systematics, identification and diagnostics, as well as practical information on culture of Leptospira. Contact information is also provided for Leptospira reference centers. All chapters were written by experts in the field, providing an invaluable reference source for scientists, veterinarians, clinicians and all others with an interest in leptospirosis.

Schaechter's Mechanisms of Microbial Disease

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Publisher : Lippincott Williams & Wilkins
ISBN 13 : 197515150X
Total Pages : 2077 pages
Book Rating : 4.9/5 (751 download)

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Book Synopsis Schaechter's Mechanisms of Microbial Disease by : N Cary Engleberg

Download or read book Schaechter's Mechanisms of Microbial Disease written by N Cary Engleberg and published by Lippincott Williams & Wilkins. This book was released on 2021-09-23 with total page 2077 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lippincott® Connect Featured Title Purchase of the new print edition of this Lippincott® Connect title includes access to the digital version of the book, plus related materials such as videos and multiple-choice Q&A and self-assessments. Known for generations as the most comprehensive foundational text on medical microbiology, Schaechter's Mechanisms of Microbial Disease delivers a thorough understanding of microbial agents and the pathophysiology of microbial diseases. This trusted text is universally praised for "telling the story of a pathogen" in an engaging way, facilitating learning and recall by emphasizing unifying principles and paradigms. Content is uniquely organized by microbial class and by organ system, making it equally at home in traditional and systems-based curricula. This updated 6th Edition reflects the latest advances in the field, including significant enhancements to the coverage of serious threats to global health, respiratory and childhood viruses, and sexually transmitted diseases. New illustrations and additional learning features further clarify concepts, reinforce understanding, and help users confidently prepare for board exams and beyond.

The National Plan to Eliminate Syphilis from the United States

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Author :
Publisher :
ISBN 13 :
Total Pages : 88 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The National Plan to Eliminate Syphilis from the United States by :

Download or read book The National Plan to Eliminate Syphilis from the United States written by and published by . This book was released on 1999 with total page 88 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Canine and Feline Infectious Diseases - E-BOOK

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Author :
Publisher : Elsevier Health Sciences
ISBN 13 : 0323241948
Total Pages : 928 pages
Book Rating : 4.3/5 (232 download)

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Book Synopsis Canine and Feline Infectious Diseases - E-BOOK by : Jane E. Sykes

Download or read book Canine and Feline Infectious Diseases - E-BOOK written by Jane E. Sykes and published by Elsevier Health Sciences. This book was released on 2013-06-06 with total page 928 pages. Available in PDF, EPUB and Kindle. Book excerpt: Canine and Feline Infectious Diseases is a practical, up-to-date resource covering the most important and cutting-edge advances in the field. Presented by a seasoned educator in a concise, highly visual format, this innovative guide keeps you current with the latest advances in this ever-changing field. 80 case studies illustrate the clinical relevance of the major infectious disease chapters. Well-organized Major Infectious Diseases chapters break down content by etiologic agent and epidemiology, clinical signs and their pathophysiology, physical examination findings, diagnosis, treatment and prognosis, immunity, prevention, and public health implications. Over 80 case studies illustrate how the information provided can be applied in everyday practice. Logical approach to laboratory diagnosis guides you through all the steps needed to accurately diagnose and treat viral, bacterial, fungal, protozoal, and algal diseases. Practical protocols provided by expert clinicians guide you in the management of canine and feline patients suspected to have infectious diseases, including handling, disinfection, isolation, and vaccination protocols. Over 500 full color images – geographic distribution maps, life cycle drawings, and hundreds of color photographs – visually illustrate and clarify complex issues. Easy-to-understand tables and boxes make content quickly accessible, eliminating the need to sort through dense text for critical information in the clinical setting.

Lyme Disease and Relapsing Fever Spirochetes

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Publisher :
ISBN 13 : 9781913652616
Total Pages : 770 pages
Book Rating : 4.6/5 (526 download)

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Book Synopsis Lyme Disease and Relapsing Fever Spirochetes by : Justin D Radolf

Download or read book Lyme Disease and Relapsing Fever Spirochetes written by Justin D Radolf and published by . This book was released on 2021 with total page 770 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lyme disease (Lyme borreliosis) is the most prevalent vector-borne illness in the United States and Europe and a growing threat to global health. In addition Lyme disease is considered a model system of emerging infectious diseases. The book Borrelia: Molecular Biology, Host Interaction and Pathogenesis published in 2010 was the first state-of-the-art reference work covering the myriad, interlaced facets of the enzootic disorders caused by pathogenic Borrelia. This current volume, by the same editors, builds on the previous work and contains a vast amount of new information, a wider scope, and increased coverage of genomics, genetics, evolutionary biology, vector biology, physiology, pathogenicity, immune response, and immune evasion. Written by renowned scientists who have made seminal contributions to the field, this book contains an expansive treatment of the options to track live spirochetes and evaluate gene expression in ticks and mice, provides insights into the workings of the flagellar motor, presents up-to-date research on the modulation of gene expression, and reviews recent studies on the Lyme disease spirochete's networks of regulatory pathways. The volume highlights and describes in detail the tremendous advances in understanding of the Borrelia genus at the molecular and cellular levels as well as the pathogenesis of Lyme disease and relapsing fever. This comprehensive volume is indispensable for anyone involved in Borrelia and Lyme disease research and is highly recommended for microbiologists, immunologists, and physicians with an interest in spirochetes, vector-borne illness, or emerging infectious diseases. The book is a recommended reference volume for all microbiology libraries.

Infectious Diseases of the Dog and Cat - E-Book

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Publisher : Elsevier Health Sciences
ISBN 13 : 0323266215
Total Pages : 1376 pages
Book Rating : 4.3/5 (232 download)

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Book Synopsis Infectious Diseases of the Dog and Cat - E-Book by : Jane E. Sykes

Download or read book Infectious Diseases of the Dog and Cat - E-Book written by Jane E. Sykes and published by Elsevier Health Sciences. This book was released on 2013-09-27 with total page 1376 pages. Available in PDF, EPUB and Kindle. Book excerpt: The definitive reference for the diagnosis, treatment, and prevention of small animal infections, Infectious Diseases of the Dog and Cat, 4th Edition delivers current, comprehensive information essential to the management of infectious diseases caused by viruses, rickettsiae, chlamydiae, mycoplasmas, bacteria, fungi, algae, protozoa, and unknown agents. Each section guides you through diagnostic testing for specific microorganisms, from sample collection to laboratory submission to interpretation of results, then details appropriate treatment measures and pharmacologic considerations for the various related infections. Full-color illustrations and hundreds of tables provide quick, convenient access to diagnostic and therapeutic guidelines, and thoroughly updated drug information helps you confidently administer appropriate dosages for the most effective treatment and prevention. The most comprehensive infectious disease coverage available helps you confidently address clinical problems related to infectious diseases in dogs and cats, and includes: Immunization strategies and environmental control of infections Immunodeficiency disorders Prevention of infection in multi-pet and shelter settings Immunocompromised people and their pets Vibrant full-color illustrations clarify disease features and modes of disease transmission for enhanced diagnostic accuracy and disease prevention. Convenient tables deliver therapeutic recommendations and drug dosages at a glance. Complete antimicrobial drug formulary provides fast, easy access to indications, recommended dosages, and pharmacologic considerations essential for all relevant pharmaceuticals. State-of-the-art diagnostic testing procedures help you ensure accurate diagnoses for all clinically relevant pathogens. Content reflects the expert insight and vast clinical experience of a panel of trusted authorities on small animal infectious diseases. Easy-to-use companion website provides convenient online access to additional images, tables, boxes, appendices, and references linked directly to original PubMed abstracts. Expanded coverage of zoonoses, zoonotic potential, and precautions helps you effectively monitor and treat zoonotic infections. Fully updated drug formulary reflects the most current pharmacokinetics, indications, contraindications, handling and administration guidelines, and dosage recommendations available. Updated content throughout the text details current diagnostic testing regimens and therapeutic and preventive considerations for all pathogens you're likely to encounter in the clinical setting. Special focus on disease incidence and susceptibility in traveling animals helps you alert animal owners to potential risks associated with pet travel.

Pet bird diseases and care

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Author :
Publisher : Springer
ISBN 13 : 9811036748
Total Pages : 296 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis Pet bird diseases and care by : Indranil Samanta

Download or read book Pet bird diseases and care written by Indranil Samanta and published by Springer. This book was released on 2017-02-24 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides fundamental information on pet birds, menaces, and advances made in the diagnosis and treatment of menaces. It is the only book covering all species of pet birds, menaces and their individual management. The handful of related books available worldwide are largely outdated and focus on a single species or breed of pet bird. The book encompasses the history of bird keeping, common breeds of birds, their nutritional requirements, list of zoonotic diseases transmitted by birds and guideline for their prevention. It covers infectious, non-infectious clinical and metabolic diseases, and toxicity in detail with a special focus on the history of diseases, etiology, affected hosts, pathogenesis, clinical signs, diagnosis and treatment. Separate chapters detail relevant diagnostic techniques, management and care practices, including updated information. The book offers an invaluable guide for students and teachers in the field of (avian) veterinary medicine, scientists/research scholars working in related fields, and avian medicine practitioners, as well as all those progressive bird owners who want to know the basics of their care and management.

Immunology and Evolution of Infectious Disease

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Publisher : Princeton University Press
ISBN 13 : 9780691095950
Total Pages : 364 pages
Book Rating : 4.0/5 (959 download)

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Book Synopsis Immunology and Evolution of Infectious Disease by : Steven A. Frank

Download or read book Immunology and Evolution of Infectious Disease written by Steven A. Frank and published by Princeton University Press. This book was released on 2002-07-21 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: Publisher Description

National Institute of Allergy and Infectious Diseases, NIH

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Publisher : Springer Science & Business Media
ISBN 13 : 1607615126
Total Pages : 434 pages
Book Rating : 4.6/5 (76 download)

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Book Synopsis National Institute of Allergy and Infectious Diseases, NIH by : Vassil St. Georgiev

Download or read book National Institute of Allergy and Infectious Diseases, NIH written by Vassil St. Georgiev and published by Springer Science & Business Media. This book was released on 2010-07-29 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: National Institute of Allergy and Infectious Diseases, NIH: Volume III: Intramural Research contains a broad overview of the research activity of the NIAID intramural scientists working in the Division of Intramural Research (DIR) and the Vaccine Research Center (VRC), both in the Bethesda campus, and the Rocky Mountains Research Laboratories. Each of these laboratories employs scientists internationally recognized as leaders in their fields of biomedical research. This volume focuses on individual research contributions by internationally known scientists doing research in the NIAID laboratories.

MRCOG Part One

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Publisher : Cambridge University Press
ISBN 13 : 1107667135
Total Pages : 557 pages
Book Rating : 4.1/5 (76 download)

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Book Synopsis MRCOG Part One by : Alison Fiander

Download or read book MRCOG Part One written by Alison Fiander and published by Cambridge University Press. This book was released on 2016-10-13 with total page 557 pages. Available in PDF, EPUB and Kindle. Book excerpt: A fully updated and illustrated handbook providing comprehensive coverage of all curriculum areas covered by the MRCOG Part 1 examination.

Current Diagnosis & Treatment in Rheumatology, Fourth Edition

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Publisher : McGraw Hill Professional
ISBN 13 : 1259644650
Total Pages : 589 pages
Book Rating : 4.2/5 (596 download)

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Book Synopsis Current Diagnosis & Treatment in Rheumatology, Fourth Edition by : John B. Imboden

Download or read book Current Diagnosis & Treatment in Rheumatology, Fourth Edition written by John B. Imboden and published by McGraw Hill Professional. This book was released on 2020-10-22 with total page 589 pages. Available in PDF, EPUB and Kindle. Book excerpt: Up-to-date, clinically relevant coverage of the entire range of rheumatology disordersThe Fourth Edition of this trusted quick-reference guide has everything clinicians need to keep pace with this fast-moving field—presented in the acclaimed find-it-now CURRENT format. A practical reference for primary care providers, the book simplifies the treatment of difficult-to-manage rheumatologic diseases and disorders, such as arthritis, lupus, and sarcoidosis. This edition is enhanced by timely new chapters, the incorporation of the ABIM’s Choosing Wisely initiative.•NEW chapters on genetics, general principles of biological therapy, and drug-induced autoimmune syndrome •Full explanations of common and major disorders in clinical immunology•Concise chapters geared to the needs of trainees and clinicians•First section addresses common but difficult-to-diagnose rheumatologic complaints—and delivers key “approach to the patient” strategies

Biology of Ticks Volume 1

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Publisher : Oxford University Press
ISBN 13 : 019974405X
Total Pages : 557 pages
Book Rating : 4.1/5 (997 download)

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Book Synopsis Biology of Ticks Volume 1 by : Daniel E. Sonenshine

Download or read book Biology of Ticks Volume 1 written by Daniel E. Sonenshine and published by Oxford University Press. This book was released on 2013-12 with total page 557 pages. Available in PDF, EPUB and Kindle. Book excerpt: Spanning two volumes, this is the most comprehensive work on tick biology and tick-borne diseases.