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Author :
Publisher : DIANE Publishing
ISBN 13 : 142890123X
Total Pages : 138 pages
Book Rating : 4.4/5 (289 download)
Download or read book Sources, Emission and Exposure for Trichloroethylene (TCE) and Related Chemicals written by and published by DIANE Publishing. This book was released on 2001 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Sources, Emission and Exposure for Trichloroethylene (TCE) and Related Chemicals written by and published by . This book was released on 2001 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher :
ISBN 13 :
Total Pages : 340 pages
Book Rating : 4.3/5 (91 download)
Download or read book Toxicological Profile for Trichloroethylene written by and published by . This book was released on 1997 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : United States. Agency for Toxic Substances and Disease Registry
Publisher :
ISBN 13 :
Total Pages : 246 pages
Book Rating : 4.3/5 (91 download)
Download or read book National Exposure Registry written by United States. Agency for Toxic Substances and Disease Registry and published by . This book was released on 1994 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309102839
Total Pages : 449 pages
Book Rating : 4.3/5 (91 download)
Download or read book Assessing the Human Health Risks of Trichloroethylene written by National Research Council and published by National Academies Press. This book was released on 2007-01-08 with total page 449 pages. Available in PDF, EPUB and Kindle. Book excerpt: Trichloroethylene is a chlorinated solvent widely used as a degreasing agent in industrial and manufacturing settings. It is also used as a chemical intermediate in making other chemicals and is a component of products such as typewriter correction fluid, paint removers, adhesives, and spot removers. In 2001, EPA issued a draft health risk assessment and proposed exposure standards for trichloroethylene. PA's Scientific Advisory Board (SAB) reviewed the draft and it was issued for public comment. A number of scientific issues were raised during the course of these reviews. Assessing the Human Health Risks of Trichloroethylene identifies and assesses the key scientific issues relevant to analyzing the human health risks of trichloroethylene, considering pertinent toxicologic, epidemiologic, population susceptibility, and other available information, including relevant published scientific literature, EPA's 2001 draft health risk assessment of trichloroethylene, scientific and technical comments received by EPA from public and private sources, and additional relevant information to be provided by the sponsoring agencies. This report highlights issues critical to the development of an objective, realistic, and scientifically balanced trichloroethylene health risk assessment. Guidance for hazard characterization of trichloroethylene is presented in Chapters 2 through 10. Chapter 2 provides guidance for evaluating large sets of epidemiologic data. In Chapter 3, the committee applies this guidance as an example in its evaluation of the epidemiologic data on trichloroethylene and kidney cancer, and this example should help guide evaluations of other cancer risks. Chapter 3 also assesses new information on the kidney toxicity of trichloroethylene and its metabolites and potential modes of action. Chapters 4, 5, 6, 7, and 8 evaluate the key issues regarding liver toxicity and cancer, reproductive and developmental toxicity, neurotoxicity, respiratory tract toxicity and cancer, and immunotoxicity, respectively. However, the committee's review focused on mode-of-action information to understand how trichloroethylene might affect certain processes differently in different species. Chapter 9 discusses susceptibility to trichloroethylene and its metabolites, and Chapter 10 describes important factors in considering trichloroethylene in mixtures. Physiologically based pharmacokinetic models are evaluated in Chapter 11, and guidance is provided on future directions for model development. Finally, Chapter 12 considers issues related to dose-response assessment and quantitative assessment of risk.
Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309051401
Total Pages : 988 pages
Book Rating : 4.3/5 (9 download)
Download or read book Environmental Medicine written by Institute of Medicine and published by National Academies Press. This book was released on 1995-05-28 with total page 988 pages. Available in PDF, EPUB and Kindle. Book excerpt: People are increasingly concerned about potential environmental health hazards and often ask their physicians questions such as: "Is the tap water safe to drink?" "Is it safe to live near power lines?" Unfortunately, physicians often lack the information and training related to environmental health risks needed to answer such questions. This book discusses six competency based learning objectives for all medical school students, discusses the relevance of environmental health to specific courses and clerkships, and demonstrates how to integrate environmental health into the curriculum through published case studies, some of which are included in one of the book's three appendices. Also included is a guide on where to obtain additional information for treatment, referral, and follow-up for diseases with possible environmental and/or occupational origins.
Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309499275
Total Pages : 77 pages
Book Rating : 4.3/5 (94 download)
Download or read book Review of DOD's Approach to Deriving an Occupational Exposure Level for Trichloroethylene written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2019-12-13 with total page 77 pages. Available in PDF, EPUB and Kindle. Book excerpt: Trichloroethylene (TCE) is a solvent that is used as a degreasing agent, a chemical intermediate in refrigerant manufacture, and a component of spot removers and adhesives. It is produced in mass quantities but creates dangerous vapors and is an environmental contaminant at many industrial and government facilities, including facilities run by the U.S. Department of Defense (DoD). It is important to determine the safe occupational exposure level (OEL) for the solvent in order to protect the health of workers who are exposed to its vapors. However, there are concerns that the current occupational standards insufficiently protect workers from these health threats. Review of DOD's Approach to Deriving an Occupational Exposure Level for Trichloroethylene makes recommendations to improve the DoD's approach to developing an OEL for TCE, strengthen transparency of the process, and improve confidence in the final OEL value. This report reviews the DoD's approach using a literature review, evidence synthesis based on weight of evidence [WOE], point-of-departure derivation, physiologically based pharmacokinetic modeling, extrapolation tools, and explores other elements of the process of deriving an OEL for TCE. It examines scientific approaches to developing exposure values and cancer risk levels, defining the scope of the problem, and improving hazard identification.
Author : Robert D Morrison
Publisher : Royal Society of Chemistry
ISBN 13 : 1782626077
Total Pages : pages
Book Rating : 4.7/5 (826 download)
Download or read book Chlorinated Solvents written by Robert D Morrison and published by Royal Society of Chemistry. This book was released on 2015-11-09 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Environmental forensics is emerging and evolving into a recognized scientific discipline with numerous applications, especially regarding chlorinated solvents. This unique book provides the reader with a concise compilation of information regarding the use of environmental forensic techniques for age dating and identification of the source of a chlorinated solvent release. Concentrating on the five commonly encountered chlorinated solvents (perchloroethylene, trichloroethylene, methyl chloroform, carbon tetrachloride and CFC-113), forensic opportunities applicable to each are presented including the use of stabilizers, manufacturing impurities, surrogate chemicals and physical measurements and degradation products as diagnostic indicators. Detailed historical chronology of the applications of the solvents and specific chapters devoted to dry cleaning and vapor degreasing equipment are included as are generic forensic approaches. Forming a basis for further ideas in the evolution of environmental forensic techniques, Chlorinated Solvents will be an indispensable reference tool for researchers, regulators and analysts in the field.
Author : Suzanne H. Reuben
Publisher : DIANE Publishing
ISBN 13 : 1437934218
Total Pages : 240 pages
Book Rating : 4.4/5 (379 download)
Download or read book Reducing Environmental Cancer Risk written by Suzanne H. Reuben and published by DIANE Publishing. This book was released on 2010-10 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Though overall cancer incidence and mortality have continued to decline in recent years, cancer continues to devastate the lives of far too many Americans. In 2009 alone, 1.5 million American men, women, and children were diagnosed with cancer, and 562,000 died from the disease. There is a growing body of evidence linking environmental exposures to cancer. The Pres. Cancer Panel dedicated its 2008¿2009 activities to examining the impact of environmental factors on cancer risk. The Panel considered industrial, occupational, and agricultural exposures as well as exposures related to medical practice, military activities, modern lifestyles, and natural sources. This report presents the Panel¿s recommend. to mitigate or eliminate these barriers. Illus.
Author :
Publisher : DIANE Publishing
ISBN 13 : 1428905391
Total Pages : 459 pages
Book Rating : 4.4/5 (289 download)
Download or read book Occurrence summary and use support document for the sixyear review of national primary drinking water regulations written by and published by DIANE Publishing. This book was released on 2002 with total page 459 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Arthur L. Frank
Publisher :
ISBN 13 :
Total Pages : 60 pages
Book Rating : 4.:/5 (319 download)
Download or read book Taking an Exposure History written by Arthur L. Frank and published by . This book was released on 2001 with total page 60 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309120462
Total Pages : 422 pages
Book Rating : 4.3/5 (91 download)
Download or read book Science and Decisions written by National Research Council and published by National Academies Press. This book was released on 2009-03-24 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: Risk assessment has become a dominant public policy tool for making choices, based on limited resources, to protect public health and the environment. It has been instrumental to the mission of the U.S. Environmental Protection Agency (EPA) as well as other federal agencies in evaluating public health concerns, informing regulatory and technological decisions, prioritizing research needs and funding, and in developing approaches for cost-benefit analysis. However, risk assessment is at a crossroads. Despite advances in the field, risk assessment faces a number of significant challenges including lengthy delays in making complex decisions; lack of data leading to significant uncertainty in risk assessments; and many chemicals in the marketplace that have not been evaluated and emerging agents requiring assessment. Science and Decisions makes practical scientific and technical recommendations to address these challenges. This book is a complement to the widely used 1983 National Academies book, Risk Assessment in the Federal Government (also known as the Red Book). The earlier book established a framework for the concepts and conduct of risk assessment that has been adopted by numerous expert committees, regulatory agencies, and public health institutions. The new book embeds these concepts within a broader framework for risk-based decision-making. Together, these are essential references for those working in the regulatory and public health fields.
Author :
Publisher :
ISBN 13 :
Total Pages : 94 pages
Book Rating : 4.3/5 (91 download)
Download or read book EPA 630/R written by and published by . This book was released on 1998 with total page 94 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Kathleen M. Gilbert
Publisher : Springer Science & Business Media
ISBN 13 : 1447163117
Total Pages : 249 pages
Book Rating : 4.4/5 (471 download)
Download or read book Trichloroethylene: Toxicity and Health Risks written by Kathleen M. Gilbert and published by Springer Science & Business Media. This book was released on 2014-02-18 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive overview of the effects of trichloroethylene toxicity caused by real-life exposure levels highlighting how exposure to trichloroethylene may contribute to the etiology of several idiopathic human diseases. Discussion will focus on different kinds of modeling and how they may be used to predict functional consequences and to dissect the contribution of different mechanistic pathways, including potential mechanisms of action for trichloroethylene toxicity in different organ systems. It will explore the role of epigenetic alterations in trichloroethylene toxicity, this provides important mechanistic information and may also provide the basis for intervention therapy. Chapters will also explain how the risks from trichloroethylene exposure may be greater in certain populations based on genetic predisposition, age of exposure and co-exposure to other chemicals With contributions from international experts in the field, Trichloroethylene: Toxicity and Health Risks is an essential resource for researchers and clinicians in toxicology, immunology, medicine and public health as well as industry and government regulatory scientists involved in safety and health protection and epidemiologists, highlighting the need for interdisciplinary cooperation in solving issues of environmental toxicity.
Author : Thomas K.G. Mohr
Publisher : CRC Press
ISBN 13 : 0203489373
Total Pages : 552 pages
Book Rating : 4.2/5 (34 download)
Download or read book Environmental Investigation and Remediation written by Thomas K.G. Mohr and published by CRC Press. This book was released on 2016-04-19 with total page 552 pages. Available in PDF, EPUB and Kindle. Book excerpt: A ubiquitous, largely overlooked groundwater contaminant, 1,4-dioxane escaped notice by almost everyone until the late 1990s. While some dismissed 1,4-dioxane because it was not regulated, others were concerned and required testing and remediation at sites they oversaw. Drawing years of 1,4-dioxane research into a convenient resource, Environmental
Author : Alexandra Maertens
Publisher : Royal Society of Chemistry
ISBN 13 : 1839162287
Total Pages : 307 pages
Book Rating : 4.8/5 (391 download)
Download or read book Green Toxicology written by Alexandra Maertens and published by Royal Society of Chemistry. This book was released on 2022-02-16 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: Green toxicology is an integral part of green chemistry. One of the key goals of green chemistry is to design less toxic chemicals. Therefore, an understanding of toxicology and hazard assessment is important for any chemist working in green chemistry, but toxicology is rarely part of most chemists' education. As a consequence, chemists lack the toxicological lens necessary to view chemicals in order to design safer substitutions. This book seeks to fill that gap and demonstrate how a basic understanding of toxicology, as well as the tools of in silico and in vitro toxicology, can be an integral part of green chemistry. R&D chemists, product stewards, and toxicologists who work in the field of sustainability, can all benefit from integrating green toxicology principles into their work. Topics include in silico tools for hazard assessment, toxicity testing, and lifecycle considerations, this book aims to act as a bridge between green toxicologists and green chemists.
Author : United States. Environmental Protection Agency
Publisher :
ISBN 13 :
Total Pages : 222 pages
Book Rating : 4.:/5 (319 download)
Download or read book EPA National Publications Catalog written by United States. Environmental Protection Agency and published by . This book was released on 2003 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt:
