Some Applications Of Fast Atom Bombardment Mass Spectrometry In Biochemistry

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Mass Spectrometry in the Biological Sciences: A Tutorial

Author : M.L Gross
Publisher : Springer Science & Business Media
ISBN 13 : 9401126186
Total Pages : 462 pages
Book Rating : 4.4/5 (11 download)

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Book Synopsis Mass Spectrometry in the Biological Sciences: A Tutorial by : M.L Gross

Download or read book Mass Spectrometry in the Biological Sciences: A Tutorial written by M.L Gross and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: The developments in mass spectrometry over the past fifteen years have been impressive in their implications in bioanalytical chemistry. The achievements begin with the inventions of Cf-252 Plasma Desorption Mass Spectrometry by Macfarlane and Fourier Transform Mass Spectrometry by Comisarow and Marshall in the mid 1970s. The former showed the feasibility of producing large gas-phase ions from large biomolecules whereas the latter enhanced the capabilities for ion trapping especially in analytical mass spectrometry. A major achievement was the development by Barber of Fast Atom Bombardment (FAB) mass spectrometry, an advance that heralded a new era in biological mass spectrometry. Contemporary and routine instruments such as magnetic sectors and quadrupoles were rapidly adapted to F AB, and nearly the entire universe of small molecules became amenable to study by mass spectrometry. The introduction of FAB also paved the way for improvement of instrument capability. For example, the upper mass limit of magnet sector mass spectrometers was increased by nearly an order of magnitude by the instrument manufacturers. Furthermore, the technique of tandem mass spectrometry (MS/MS) was given new meaning because important structural information for biomolecules could now be produced for ions introduced by FAB into the tandem instrument. The evolution of MS/MS continues today with the development of ion traps, time-of-flight, and sector instruments equipped with array detection.

Mass Spectrometry in Biomolecular Sciences

Author : Richard M. Caprioli
Publisher : Springer Science & Business Media
ISBN 13 : 9400902174
Total Pages : 531 pages
Book Rating : 4.4/5 (9 download)

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Book Synopsis Mass Spectrometry in Biomolecular Sciences by : Richard M. Caprioli

Download or read book Mass Spectrometry in Biomolecular Sciences written by Richard M. Caprioli and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 531 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mass Spectrometry in the Biological Sciences covers the most recent technological and applied developments in the area, including both ionization techniques and ion analysis. It introduces and reviews some of the newer ionization methods, describes the major instrumentation involved in mass analysis, and presents the scope of the technology in biology, medicine, and environmental science. Specific examples are given for a number of topics. It also deals with recent achievements in the on-line combination of separation techniques such as gas chromatography, liquid chromatography, and supercritical fluid technology.

Laboratory Methodology in Biochemistry

Author : C. Fini
Publisher : CRC Press
ISBN 13 : 135108237X
Total Pages : 276 pages
Book Rating : 4.3/5 (51 download)

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Book Synopsis Laboratory Methodology in Biochemistry by : C. Fini

Download or read book Laboratory Methodology in Biochemistry written by C. Fini and published by CRC Press. This book was released on 2019-08-08 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biochemistry Physical Biochemistry Molecular Biology Clinical Biochemistry Biochemical Technology Applied Biochemistry Cellular Biology

Mass Spectrometry

Author : Edmond de Hoffmann
Publisher : Wiley
ISBN 13 : 9780471485650
Total Pages : 420 pages
Book Rating : 4.4/5 (856 download)

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Book Synopsis Mass Spectrometry by : Edmond de Hoffmann

Download or read book Mass Spectrometry written by Edmond de Hoffmann and published by Wiley. This book was released on 2001-10-10 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: Offers a complete overview of the principles, theories and key applications of modern mass spectrometry in this introductory textbook. Following on from the highly successful first edition, this edition is extensively updated including new techniques and applications. All instrumental aspects of mass spectrometry are clearly and concisely described; sources, analysers and detectors. * Revised and updated * Numerous examples and illustrations are combined with a series of exercises to help encourage student understanding * Includes biological applications, which have been significantly expanded and updated * Also includes coverage of ESI and MALDI

Selected Topics in Mass Spectrometry in the Biomolecular Sciences

Author : Richard M. Caprioli
Publisher : Springer Science & Business Media
ISBN 13 : 9401151652
Total Pages : 589 pages
Book Rating : 4.4/5 (11 download)

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Book Synopsis Selected Topics in Mass Spectrometry in the Biomolecular Sciences by : Richard M. Caprioli

Download or read book Selected Topics in Mass Spectrometry in the Biomolecular Sciences written by Richard M. Caprioli and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 589 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many fundamental aspects of the methods used in mass spectrometry are here presented by outstanding scientists, with reference to very recent developments. The principles and applications of electrospray, ion spray and MALDI ionization technique are presented, together with optimised GC/MS interfacing systems and tools for quantitative analysis. A comprehensive treatment of modern instrumentation for mass analysis and detection is also included. The major part of the book deals with bioanalytical applications to peptides, proteins, oligonucleotides, polysaccharides, lipids and plant metabolites. Several papers are devoted to the evaluation of adduct formation between DNA and carcinogens. Environmental applications are also included, with examples of some specific cases. Fundamentals and applications are treated with the same degree of depth: the first two parts of the book therefore provide a basis for the understanding of the biomolecular applications section. Audience: Ideal for advanced graduate students of chemistry who have learned some basic mass spectrometry. Also useful for Ph.D. students in chemistry, biology and medicine. Of value to researchers in academic and industrial laboratories.

Introduction to Mass Spectrometry

Author : J. Throck Watson
Publisher : John Wiley & Sons
ISBN 13 : 1118681584
Total Pages : 972 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis Introduction to Mass Spectrometry by : J. Throck Watson

Download or read book Introduction to Mass Spectrometry written by J. Throck Watson and published by John Wiley & Sons. This book was released on 2013-07-09 with total page 972 pages. Available in PDF, EPUB and Kindle. Book excerpt: Completely revised and updated, this text provides an easy-to-read guide to the concept of mass spectrometry and demonstrates its potential and limitations. Written by internationally recognised experts and utilising "real life" examples of analyses and applications, the book presents real cases of qualitative and quantitative applications of mass spectrometry. Unlike other mass spectrometry texts, this comprehensive reference provides systematic descriptions of the various types of mass analysers and ionisation, along with corresponding strategies for interpretation of data. The book concludes with a comprehensive 3000 references. This multi-disciplined text covers the fundamentals as well as recent advance in this topic, providing need-to-know information for researchers in many disciplines including pharmaceutical, environmental and biomedical analysis who are utilizing mass spectrometry

Protein/Peptide Sequence Analysis: Current Methodologies

Author : A.S. Bhown
Publisher : CRC Press
ISBN 13 : 1351084534
Total Pages : 251 pages
Book Rating : 4.3/5 (51 download)

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Book Synopsis Protein/Peptide Sequence Analysis: Current Methodologies by : A.S. Bhown

Download or read book Protein/Peptide Sequence Analysis: Current Methodologies written by A.S. Bhown and published by CRC Press. This book was released on 2018-02-01 with total page 251 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is an attempt to provide in a single source current state-of-the-art methodologies for protein sequence analysis. It is hoped that these various chapters are presented in such a way that both the newcomer and the established protein chemist will find useful information and directions to new techniques. This book offers a rich array of techniques and methods for sequencing proteins and peptides. It should meet the expectations of investigators in protein chemistry who wish to update their knowledge of sequencing techniques, and of those who wish to reacquaint themselves with the best available current technologies.

Electrospray and MALDI Mass Spectrometry

Author : Richard B. Cole
Publisher : John Wiley & Sons
ISBN 13 : 1118211553
Total Pages : 900 pages
Book Rating : 4.1/5 (182 download)

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Book Synopsis Electrospray and MALDI Mass Spectrometry by : Richard B. Cole

Download or read book Electrospray and MALDI Mass Spectrometry written by Richard B. Cole and published by John Wiley & Sons. This book was released on 2011-09-26 with total page 900 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discover how advances in mass spectrometry are fueling new discoveries across a broad range of research areas Electrospray and MALDI Mass Spectrometry brings both veteran practitioners and beginning scientists up to date with the most recent trends and findings in electrospray ionization and matrix-assisted laser desorption/ionization (MALDI) mass spectrometry. In particular, this Second Edition highlights how advances in electrospray and MALDI mass spectrometry are supporting important discoveries in new and emerging fields such as proteomics and metabolomics as well as in traditional areas of chemistry and physics research. Electrospray AND MALDI Mass Spectrometry, SECOND EDITION is divided into five parts: Part A, Fundamentals of ES, explains the fundamental phenomena underlying the electrospray process, including selectivity in ionization and inherent electrochemistry, and concludes with a chapter offering a comparative inventory of source hardware Part B, Fundamentals of MALDI, confronts ionization mechanisms, instrument development, and matrix selection, and includes a final chapter that explores the special application of MALDI to obtain two-dimensional images of spatial distributions of compounds on surfaces Part C, ES and MALDI Coupling to Mass Spectrometry Instrumentation, examines the coupling of these ionization techniques to various mass analyzers, including quadrupole ion trap, time-of-flight, Fourier transform ion cyclotron resonance, and ion mobility mass spectrometers Part D, Practical Aspects of ES and MALDI, investigates analytical issues including quantification, charge-state distributions, noncovalent interactions in solution that are preserved as gas-phase ions, and various means of ion excitation in preparation for tandem mass spectrometry, and offers a guide to the interpretation of even-electron mass spectra Part E, Biological Applications of ES and MALDI, examines the role of mass spectrometry in such areas as peptide and protein characterization, carbohydrate analysis, lipid analysis, and drug discovery Written by a team of leading experts, the book not only provides a critical review of the literature, but also presents key concepts in tutorial fashion to help readers take full advantage of the latest technological breakthroughs and applications. As a result, Electrospray and MALDI Mass Spectrometry will help researchers fully leverage the power of electrospray and MALDI mass spectrometry. The judicious compartmentalization of chapters, and the pedagogic presentation style throughout, render the book highly suitable for use as a text for graduate-level courses in advanced mass spectrometry.

Mass Spectrometry of Nucleosides and Nucleic Acids

Author : Joseph H. Banoub
Publisher : CRC Press
ISBN 13 : 1420044036
Total Pages : 506 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Mass Spectrometry of Nucleosides and Nucleic Acids by : Joseph H. Banoub

Download or read book Mass Spectrometry of Nucleosides and Nucleic Acids written by Joseph H. Banoub and published by CRC Press. This book was released on 2009-12-21 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: Assembling the work of an international panel of researchers, Mass Spectrometry of Nucleosides and Nucleic Acids summarizes and reviews the latest developments in the field and provides a window on the next generation of analysis. Beginning with an overview of recent developments, the book highlights the most popular ionization methods and illustra

Mass Spectrometry of Peptides

Author : Dominic M. Desiderio
Publisher : CRC Press
ISBN 13 : 9780849362934
Total Pages : 438 pages
Book Rating : 4.3/5 (629 download)

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Book Synopsis Mass Spectrometry of Peptides by : Dominic M. Desiderio

Download or read book Mass Spectrometry of Peptides written by Dominic M. Desiderio and published by CRC Press. This book was released on 1990-11-14 with total page 438 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of this book is to collect into one volume the research done on the mass spectrometry of peptides. It balances a range of topics including theory, instrumentation, analytical techniques, and biological applications. The scope of the work contains three major sections: ionization methods, instrumental developments, and analysis of peptides. It describes 252Cf plasma desorption and laser-induced multiphoton ionization methodology. This exciting resource covers many new areas, including continuous flow FAB, quantification of human neuropeptides, and peptide mapping. It also discusses Q-FTMS, cross-links, and metal ions.

Chemistry and Significance of Condensed Tannins

Author : Richard W. Hemingway
Publisher : Springer Science & Business Media
ISBN 13 : 1468475118
Total Pages : 539 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis Chemistry and Significance of Condensed Tannins by : Richard W. Hemingway

Download or read book Chemistry and Significance of Condensed Tannins written by Richard W. Hemingway and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 539 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book was developed from the proceedings of the first North American Tannin Conference held in Port. Angeles, Washington, August 1988. The objective of the conference was to bring together people with a common interest in condensed tannins and to promote interdisciplinary interactions that will lead to a better understanding of these important substances. Anot. her objective was the publicat. ion of this book because there has not been a monograph devoted to the chemistry and significance of tannins for several decades. The book is organized into sections dealing with the biosynthesis, structure, re actions, complexation with other biopolymers, biological significance, and use of tannins as specialty chemicals. The authors made a special attempt to focus on what we don't know as well as to provide a summary of what we do know in an effort to assist in planning future research. Our thanks go to the authors who so kindly contributed chapters and so pa tiently responded to our requests. We also thank Rylee Geboski and the Conference Assist. ance Staff, College of Forestry, Oregon State University, for their assistance in planning and conducting t. he conference, and Julia Wilson, Debbie Wolfe, Helen Coletka, and Nancy Greene of the Southern Forest Experiment Station, Pineville, Louisiana, who typed the chapt. ers. Linda Chalker-Scott was especially helpful in assisting us wit. h editing. Dick Hemingway is indebted t. o the staff of the Alexandria Forest.

Spectroscopic Analyses

Author : Eram Sharmin
Publisher : BoD – Books on Demand
ISBN 13 : 9535136275
Total Pages : 242 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Spectroscopic Analyses by : Eram Sharmin

Download or read book Spectroscopic Analyses written by Eram Sharmin and published by BoD – Books on Demand. This book was released on 2017-12-06 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book presents developments and applications of these methods, such as NMR, mass, and others, including their applications in pharmaceutical and biomedical analyses. The book is divided into two sections. The first section covers spectroscopic methods, their applications, and their significance as characterization tools; the second section is dedicated to the applications of spectrophotometric methods in pharmaceutical and biomedical analyses. This book would be useful for students, scholars, and scientists engaged in synthesis, analyses, and applications of materials/polymers.

Handbook of Food Analytical Chemistry, Volume 1

Author : Ronald E. Wrolstad
Publisher : John Wiley & Sons
ISBN 13 : 0471709093
Total Pages : 1397 pages
Book Rating : 4.4/5 (717 download)

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Book Synopsis Handbook of Food Analytical Chemistry, Volume 1 by : Ronald E. Wrolstad

Download or read book Handbook of Food Analytical Chemistry, Volume 1 written by Ronald E. Wrolstad and published by John Wiley & Sons. This book was released on 2005-09-02 with total page 1397 pages. Available in PDF, EPUB and Kindle. Book excerpt: Emphasizing effective, state-of-the art methodology and written by recognized experts in the field, the Handbook of Food Analytical Chemistry is an indispensable reference for food scientists and technologists to enable successful analysis. * Provides detailed reports on experimental procedures * Includes sections on background theory and troubleshooting * Emphasizes effective, state-of-the art methodology, written by recognized experts in the field * Includes detailed instructions with annotated advisory comments, key references with annotation, time considerations and anticipated results

Proteome Characterization and Proteomics

Author : Timothy D. Veenstra
Publisher : Academic Press
ISBN 13 : 0080569153
Total Pages : 445 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Proteome Characterization and Proteomics by : Timothy D. Veenstra

Download or read book Proteome Characterization and Proteomics written by Timothy D. Veenstra and published by Academic Press. This book was released on 2003-10-01 with total page 445 pages. Available in PDF, EPUB and Kindle. Book excerpt: The content of this volume is designed to reach a wide audience, including those involved with relevant technologies such as electrophoresis and mass spectrometry, to those interested in how proteomics can benefit research. A wide range of techniques are discussed, each specifically designed to address different needs in proteomic analysis. The concluding chapter discusses the important issue related to handling large amounts of data accumulated in proteomic studies. - Discusses proteomics in the postgenomic age - Includes various strategies for quantitative proteomics - Covers the role of MS in structural functional proteomics and proteomics in drug discovery and bioinformatics

Cumulated Index Medicus

Author :
Publisher :
ISBN 13 :
Total Pages : 1094 pages
Book Rating : 4.3/5 (243 download)

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Book Synopsis Cumulated Index Medicus by :

Download or read book Cumulated Index Medicus written by and published by . This book was released on 1985 with total page 1094 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Published Scientific Papers of the National Institutes of Health

Author : National Institutes of Health (U.S.).
Publisher :
ISBN 13 :
Total Pages : 564 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Published Scientific Papers of the National Institutes of Health by : National Institutes of Health (U.S.).

Download or read book Published Scientific Papers of the National Institutes of Health written by National Institutes of Health (U.S.). and published by . This book was released on 1990 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents the broad outline of NIH organizational structure, theprofessional staff, and their scientific and technical publications covering work done at NIH.

Biomedical Technology Resources

Author : Barry Leonard
Publisher : DIANE Publishing
ISBN 13 : 0788141872
Total Pages : 93 pages
Book Rating : 4.7/5 (881 download)

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Book Synopsis Biomedical Technology Resources by : Barry Leonard

Download or read book Biomedical Technology Resources written by Barry Leonard and published by DIANE Publishing. This book was released on 1998-08 with total page 93 pages. Available in PDF, EPUB and Kindle. Book excerpt: Promotes access to a network of biomedical technology resource centers throughout the nation. These centers make state-of-the-art technologies & methods available to thousands of biomedical investigators each year. The directory is organized into scientific areas: biomedical computing, biochemical materials, biomedical engineering, non-invasive imaging & spectroscopy, & cellular & molecular structure & function. Each entry includes the principal investigator & control person, the research being conducted, & capabilities of the resource that are available to outside investigators.