Small Molecule Matrix Free Laser Desorption Ionization Mass Spectrometry

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Mass Spectrometry Imaging of Small Molecules

Author : Lin He
Publisher : Humana Press
ISBN 13 : 9781493913565
Total Pages : 0 pages
Book Rating : 4.9/5 (135 download)

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Book Synopsis Mass Spectrometry Imaging of Small Molecules by : Lin He

Download or read book Mass Spectrometry Imaging of Small Molecules written by Lin He and published by Humana Press. This book was released on 2014-11-01 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mass Spectroscopy Imaging (MSI) has emerged as an enabling technique to provide insight into the molecular entities within cells, tissues and whole-body samples and to understand inherent complexities within biological metabolomes. In Mass Spectrometry Imaging of Small Molecules: Methods and Protocols, experts in the MSI field present techniques for 2D and 3D visualization and quantification of a wide array of small molecular species present in biologically relevant samples. Chapters provide detailed operational instructions from sample preparation to method selection, from comparative quantification to structural identification and from data collection to visualization of small molecule mapping in complex samples. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Mass Spectrometry Imaging of Small Molecules: Methods and Protocols aims to bring the rapidly maturing methods of metabolic imaging to life science researchers and to minimize technical intimidation in adapting new technological platforms in biological research.

Photoionization and Photo-Induced Processes in Mass Spectrometry

Author : Ralf Zimmermann
Publisher : John Wiley & Sons
ISBN 13 : 3527335102
Total Pages : 448 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Photoionization and Photo-Induced Processes in Mass Spectrometry by : Ralf Zimmermann

Download or read book Photoionization and Photo-Induced Processes in Mass Spectrometry written by Ralf Zimmermann and published by John Wiley & Sons. This book was released on 2021-07-06 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides comprehensive coverage of laser-induced ionization processes for mass spectrometry analysis Drawing on the expertise of the leading academic and industrial research groups involved in the development of photoionization methods for mass spectrometry, this reference for analytical scientists covers both the theory and current applications of photo-induced ionization processes. It places widely used techniques such as MALDI side by side with more specialist approaches such as REMPI and RIMS, and discusses leading edge developments in ultrashort laser pulse desorption, to give readers a complete picture of the state of the technology. Photoionization and Photo-Induced Processes in Mass Spectrometry: Fundamentals and Applications starts with a complete overview of the fundamentals of the technique, covering the basics of the gas phase ionization as well as those of laser desorption and ablation, pulse photoionization, and single particle ionization. Numerous application examples from different analytical fields are described that showcase the power and the wide scope of photo ionization in mass spectrometry. -The first general reference book on photoionization techniques for mass spectrometry -Examines technologies and applications of gas phase resonance-enhanced multiphoton ionization mass spectrometry (REMPI-MS) and gas phase resonance ionization mass spectrometry (RIMS) -Provides complete coverage of popular techniques like MALDI -Discusses the current and potential applications of each technology, focusing on process and environmental analysis Photoionization and Photo-Induced Processes in Mass Spectrometry: Fundamentals and Applications is an excellent book for spectroscopists, analytical chemists, photochemists, physical chemists, and laser specialists.

Electrowetting

Author : Frieder Mugele
Publisher : John Wiley & Sons
ISBN 13 : 3527412298
Total Pages : 323 pages
Book Rating : 4.5/5 (274 download)

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Book Synopsis Electrowetting by : Frieder Mugele

Download or read book Electrowetting written by Frieder Mugele and published by John Wiley & Sons. This book was released on 2019-04-29 with total page 323 pages. Available in PDF, EPUB and Kindle. Book excerpt: Starting from the basic principles of wetting, electrowetting and fluid dynamics all the way up to those engineering aspects relevant for the development of specific devices, this is a comprehensive introduction and overview of the theoretical and practical aspects. Written by two of the most knowledgeable experts in the field, the text covers both current as well as possible future applications, providing basic working principles of lab-on-a-chip devices and such optofluidic devices as adaptive lenses and optical switches. Furthermore, novel e-paper display technology, energy harvesting and supercapacitors as well as electrowetting in the nano-world are discussed. Finally, the book contains a series of exercises and questions for use in courses on microfluidics or electrowetting. With its all-encompassing scope, this book will equally serve the growing community of students and academic and industrial researchers as both an introduction and a standard reference.

MALDI MS

Author : Franz Hillenkamp
Publisher : John Wiley & Sons
ISBN 13 : 3527333312
Total Pages : 0 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis MALDI MS by : Franz Hillenkamp

Download or read book MALDI MS written by Franz Hillenkamp and published by John Wiley & Sons. This book was released on 2013-12-23 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This authoritative book on MALDI MS, now finally available in its second edition and edited by one of its inventors, gives an in-depth description of the many different applications, along with a detailed discussion of the technology itself. Thoroughly updated and expanded, with contributions from key players in the field, this unique book provides a comprehensive overview of MALDI MS along with its possibilities and limitations. The initial chapters deal with the technology and the instrumental setup, followed by chapters on the use of MALDI MS in protein research (including proteomics), genomics, glycomics and lipidomics. The option of MALDI-MS for the analysis of polymers and small molecules are also covered in separate chapters, while new to this edition is a section devoted to the interplay of MALDI MS and bioinformatics. A much-needed practical and educational asset for individuals, academic institutions and companies in the field of bioanalytics.

Ambient Ionization Mass Spectrometry

Author : Marek Domin
Publisher : Royal Society of Chemistry
ISBN 13 : 1849739269
Total Pages : 528 pages
Book Rating : 4.8/5 (497 download)

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Book Synopsis Ambient Ionization Mass Spectrometry by : Marek Domin

Download or read book Ambient Ionization Mass Spectrometry written by Marek Domin and published by Royal Society of Chemistry. This book was released on 2014-11-25 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ambient ionization has emerged as one of the hottest and fastest growing topics in mass spectrometry enabling sample analysis with minimal sample preparation. Introducing the subject and explaining the basic concepts and terminology, this book will provide a comprehensive, unique treatise devoted to the subject. Written by acknowledged experts, there are full descriptions on how new ionization techniques work, with an overview of their strengths, weaknesses and applications. This title will bring the reader right up to date, with both applications and theory, and will be suitable as a tutorial text for those starting in the field from a variety of disciplines.

Laser Desorption Ionization Mass Spectrometry Based on Nanophotonic Structure: From Material Design to Mechanistic Understanding

Download Laser Desorption Ionization Mass Spectrometry Based on Nanophotonic Structure: From Material Design to Mechanistic Understanding PDF Online Free

Author : Moon-Ju Kim
Publisher : Springer Nature
ISBN 13 : 981996878X
Total Pages : 107 pages
Book Rating : 4.8/5 (199 download)

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Book Synopsis Laser Desorption Ionization Mass Spectrometry Based on Nanophotonic Structure: From Material Design to Mechanistic Understanding by : Moon-Ju Kim

Download or read book Laser Desorption Ionization Mass Spectrometry Based on Nanophotonic Structure: From Material Design to Mechanistic Understanding written by Moon-Ju Kim and published by Springer Nature. This book was released on 2023-11-11 with total page 107 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents innovative laser desorption ionization (LDI)-active nanophotonic structures for addressing the challenges that matrix-assisted laser desorption ionization mass spectrometry (MALDI-MS) is currently facing and for enhancing LDI efficiency. It presents a variety of cutting-edge nanophotonic structures to satisfy the mass-analytical needs of sensitivity, reproducibility, and quantification. As opposed to the commercialized, conventional organic matrix used in MALDI-MS, these nanostructures are validated to be highly effective in detecting small metabolites and drugs, highlighting their considerable potential in the mass spectrometry field. It also systematically elucidates fundamental LDI processes in terms of the photo-thermal, electronic, and structural characteristics of nanophotonic structures, offering mechanistic knowledge of LDI-MS. Even though LDI-MS performance is heavily influenced by a number of nanostructure parameters, relatively little is known about the LDI processes associated with those characteristics. An in-depth understanding of nanostructure characteristics and LDI mechanisms thus paves the way for more effective, rational design and development of nanostructures with improved LDI capabilities. Further, with a focus on multiple cascades in nanostructure functions in response to laser pulse stimuli, this book provides detailed, step-by-step procedures to design and construct a nanophotonic, LDI-active platform, which may serve as a roadmap for graduate students in the field of mass spectrometry. Readers, including graduate students, researchers, and experts working in the related areas of mass spectrometry, nanophotonics, and material science and material engineering, will find a wealth of useful information in this book.

Mass Spectrometry of Polymers

Author : Giorgio Montaudo
Publisher : CRC Press
ISBN 13 : 1420037757
Total Pages : 601 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Mass Spectrometry of Polymers by : Giorgio Montaudo

Download or read book Mass Spectrometry of Polymers written by Giorgio Montaudo and published by CRC Press. This book was released on 2001-10-29 with total page 601 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mass Spectrometry (MS) has rapidly become an indispensable tool in polymer analysis, and modern MS today complements in many ways the structural data provided by Nuclear Magnetic Resonance (NMR) and Infrared (IR) methods. Recent advances have sparked a growing interest in this field and established a need for a summary of progress made and results

MALDI Mass Spectrometry Imaging

Author : Tiffany Siegel Porta
Publisher : Royal Society of Chemistry
ISBN 13 : 1839162414
Total Pages : 541 pages
Book Rating : 4.8/5 (391 download)

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Book Synopsis MALDI Mass Spectrometry Imaging by : Tiffany Siegel Porta

Download or read book MALDI Mass Spectrometry Imaging written by Tiffany Siegel Porta and published by Royal Society of Chemistry. This book was released on 2021-12-03 with total page 541 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gathers knowledge about matrix-assisted laser desorption ionisation (MALDI) mass spectrometry imaging for postgraduate and professional researchers in academia and in industry where it has direct application to clinical research.

Applications of MALDI-TOF Spectroscopy

Author : Zongwei Cai
Publisher : Springer
ISBN 13 : 3642356656
Total Pages : 220 pages
Book Rating : 4.6/5 (423 download)

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Book Synopsis Applications of MALDI-TOF Spectroscopy by : Zongwei Cai

Download or read book Applications of MALDI-TOF Spectroscopy written by Zongwei Cai and published by Springer. This book was released on 2014-07-08 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: MALDI-ToF Mass Spectrometry for Studying Noncovalent Complexes of Biomolecules, by Stefanie Mädler, Elisabetta Boeri Erba, Renato Zenobi Application of MALDI-TOF-Mass Spectrometry to Proteome Analysis Using Stain-Free Gel Electrophoresis, by Iuliana Susnea, Bogdan Bernevic, Michael Wicke, Li Ma, Shuying Liu, Karl Schellander, Michael Przybylski MALDI Mass Spectrometry for Nucleic Acid Analysis, by Xiang Gao, Boon-Huan Tan, Richard J. Sugrue, Kai Tang Determination of Peptide and Protein Disulfide Linkages by MALDI Mass Spectrometry, by Hongmei Yang, Ning Liu, Shuying Liu MALDI In-Source Decay, from Sequencing to Imaging, by Delphine Debois, Nicolas Smargiasso, Kevin Demeure, Daiki Asakawa, Tyler A. Zimmerman, Loïc Quinton, Edwin De Pauw Advances of MALDI-TOF MS in the Analysis of Traditional Chinese Medicines, by Minghua Lu, Zongwei Cai Chemical and Biochemical Applications of MALDI TOF-MS Based on Analyzing the Small Organic Compounds, by Haoyang Wang, Zhixiong Zhao, Yinlong Guo Bioinformatic Analysis of Data Generated from MALDI Mass Spectrometry for Biomarker Discovery, by Zengyou He, Robert Z. Qi, Weichuan Yu

Handbook of Smart Materials in Analytical Chemistry

Author : Miguel de la Guardia
Publisher : John Wiley & Sons
ISBN 13 : 1119422590
Total Pages : 996 pages
Book Rating : 4.1/5 (194 download)

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Book Synopsis Handbook of Smart Materials in Analytical Chemistry by : Miguel de la Guardia

Download or read book Handbook of Smart Materials in Analytical Chemistry written by Miguel de la Guardia and published by John Wiley & Sons. This book was released on 2019-01-24 with total page 996 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive guide to smart materials and how they are used in sample preparation, analytical processes, and applications This comprehensive, two-volume handbook provides detailed information on the present state of new materials tailored for selective sample preparation and the legal frame and environmental side effects of the use of smart materials for sample preparation in analytical chemistry, as well as their use in the analytical processes and applications. It covers both methodological and applied analytical aspects, relating to the development and application of new materials for solid-phase extraction (SPE) and solid-phase microextraction (SPME), their use in the different steps and techniques of the analytical process, and their application in specific fields such as water, food, air, pharmaceuticals, clinical sciences and forensics. Every chapter in Handbook of Smart Materials in Analytical Chemistry is written by experts in the field to provide a comprehensive picture of the present state of this key area of analytical sciences and to summarize current applications and research literature in a critical way. Volume 1 covers New Materials for Sample Preparation and Analysis. Volume 2 handles Analytical Processes and Applications. Focuses on the development and applications of smart materials in analytical chemistry Covers both, methodological and applied analytical aspects, for the development of new materials and their use in the different steps and techniques of the analytical process and their application in specific fields Features applications in key areas including water, air, environment, pharma, food, forensic, and clinical Presents the available tools for the use of new materials suitable to aid recognition process to the sample preparation and analysis A key resource for analytical chemists, applied laboratories, and instrument companies Handbook of Smart Materials in Analytical Chemistry, 2V Set is an excellent reference book for specialists and advanced students in the areas of analytical chemistry, including both research and application environments.

Fundamentals of MALDI-ToF-MS Analysis

Author : Samira Hosseini
Publisher : Springer
ISBN 13 : 9811023565
Total Pages : 76 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis Fundamentals of MALDI-ToF-MS Analysis by : Samira Hosseini

Download or read book Fundamentals of MALDI-ToF-MS Analysis written by Samira Hosseini and published by Springer. This book was released on 2016-08-18 with total page 76 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the fundamentals and applications of Matrix Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry (MALDI-ToF-MS) technique. It highlights the basic principles, the history of invention as well as the mechanism of ionization and mass determination using this technique. It describes the fundamental principles and methods for MALDI spectra interpretation and determination of exact chemical structures from experimental data. This book guides the reader through the interpretation of MALDI data where complex macromolecular spectra are simplified in order to present the major principles behind data interpretation. In addition, each chapter describes how MALDI-ToF-MS analysis provides necessary understanding of the copolymer systems that have been designed for specialized biomedical applications.

Mass Spectrometry in Medicinal Chemistry

Author : Klaus Wanner
Publisher : John Wiley & Sons
ISBN 13 : 352761091X
Total Pages : 460 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Mass Spectrometry in Medicinal Chemistry by : Klaus Wanner

Download or read book Mass Spectrometry in Medicinal Chemistry written by Klaus Wanner and published by John Wiley & Sons. This book was released on 2007-06-27 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: This first overview of mass spectrometry-based pharmaceutical analysis is the key to improved high-throughput drug screening, rational drug design and analysis of multiple ligand-target interactions. The ready reference opens with a general introduction to the use of mass spectrometry in pharmaceutical screening, followed by a detailed description of recently developed analytical systems for use in the pharmaceutical laboratory. Applications range from simple binding assays to complex screens of biological activity and systems containing multiple targets or ligands -- all highly relevant techniques in the early stages in drug discovery, from target characterization to hit and lead finding.

Mass Spectrometry in Polymer Chemistry

Author : Christopher Barner-Kowollik
Publisher : John Wiley & Sons
ISBN 13 : 3527641831
Total Pages : 501 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Mass Spectrometry in Polymer Chemistry by : Christopher Barner-Kowollik

Download or read book Mass Spectrometry in Polymer Chemistry written by Christopher Barner-Kowollik and published by John Wiley & Sons. This book was released on 2012-01-27 with total page 501 pages. Available in PDF, EPUB and Kindle. Book excerpt: Combining an up-to-date insight into mass-spectrometric polymer analysis beyond MALDI with application details of the instrumentation, this is a balanced and thorough presentation of the most important and widely used mass-spectrometric methods. Written by the world's most proficient experts in the field, the book focuses on the latest developments, covering such technologies and applications as ionization protocols, tandem and liquid chromatography mass spectrometry, gas-phase ion-separation techniques and automated data processing. Chapters on sample preparation, polymer degradation and the usage of mass-spectrometric tools on an industrial scale round off the book. As a result, both entrants to the field and experienced researchers are able to choose the appropriate methods and instrumentations -- and to assess their respective strengths and limitations -- for the characterization of polymer compounds.

Semiconductor Nanomaterials

Author : Challa S. S. R. Kumar
Publisher : John Wiley & Sons
ISBN 13 : 3527321667
Total Pages : 499 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Semiconductor Nanomaterials by : Challa S. S. R. Kumar

Download or read book Semiconductor Nanomaterials written by Challa S. S. R. Kumar and published by John Wiley & Sons. This book was released on 2010-04-05 with total page 499 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book series Nanomaterials for the Life Sciences, provides an in-depth overview of all nanomaterial types and their uses in the life sciences. Each volume is dedicated to a specific material class and covers fundamentals, synthesis and characterization strategies, structure-property relationships and biomedical applications. The series brings nanomaterials to the Life Scientists and life science to the Materials Scientists so that synergies are seen and developed to the fullest. Written by international experts of various facets of this exciting field of research, the series is aimed at scientists of the following disciplines: biology, chemistry, materials science, physics, bioengineering, and medicine, together with cell biology, biomedical engineering, pharmaceutical chemistry, and toxicology, both in academia and fundamental research as well as in pharmaceutical companies. VOLUME 6 - Semiconductor Nanomaterials

Introduction to Spatial Mapping of Biomolecules by Imaging Mass Spectrometry

Author : Bindesh Shrestha
Publisher : Elsevier
ISBN 13 : 0128189991
Total Pages : 272 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Introduction to Spatial Mapping of Biomolecules by Imaging Mass Spectrometry by : Bindesh Shrestha

Download or read book Introduction to Spatial Mapping of Biomolecules by Imaging Mass Spectrometry written by Bindesh Shrestha and published by Elsevier. This book was released on 2021-04-23 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: Imaging mass spectrometry (MS) techniques are often utilized without an understanding of their underlying principles, making it difficult for scientists to determine when and how they can exploit MS to visualize their biomolecules of interest. Introduction to Spatial Mapping of Biomolecules by Imaging Mass Spectrometry is an essential reference to help scientists determine the status and strategies of biomolecule analysis, describing its many applications for diverse classes of biomolecules. The book builds a foundation of imaging MS knowledge by introducing ionization sources, sample preparation, visualization guidelines, molecule identification, quantification, data analysis, etc. The second section contains chapters focused on case studies on analyzing a biomolecule class of molecules. Case studies include an introduction/background, and a summary of successful imaging MS studies with illustrative figures and future directions. - Provides the introductory foundations of imaging mass spectrometry for those new to the technique - Organized by topic to facilitate a quick deep dive, allowing researchers to immediately apply the imaging MS techniques to their work - Includes case studies summarizing the imaging MS techniques developed for the class of molecules

Omics Technologies and Bio-engineering

Author : Debmalya Barh
Publisher : Academic Press
ISBN 13 : 0128047496
Total Pages : 645 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Omics Technologies and Bio-engineering by : Debmalya Barh

Download or read book Omics Technologies and Bio-engineering written by Debmalya Barh and published by Academic Press. This book was released on 2017-12-01 with total page 645 pages. Available in PDF, EPUB and Kindle. Book excerpt: Omics Technologies and Bio-Engineering: Towards Improving Quality of Life, Volume 1 is a unique reference that brings together multiple perspectives on omics research, providing in-depth analysis and insights from an international team of authors. The book delivers pivotal information that will inform and improve medical and biological research by helping readers gain more direct access to analytic data, an increased understanding on data evaluation, and a comprehensive picture on how to use omics data in molecular biology, biotechnology and human health care. - Covers various aspects of biotechnology and bio-engineering using omics technologies - Focuses on the latest developments in the field, including biofuel technologies - Provides key insights into omics approaches in personalized and precision medicine - Provides a complete picture on how one can utilize omics data in molecular biology, biotechnology and human health care

Secondary Ion Mass Spectrometry

Author : J. C. Vickerman
Publisher : Oxford University Press, USA
ISBN 13 :
Total Pages : 368 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Secondary Ion Mass Spectrometry by : J. C. Vickerman

Download or read book Secondary Ion Mass Spectrometry written by J. C. Vickerman and published by Oxford University Press, USA. This book was released on 1989 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an overview of the phenomenology, technology and application of secondary ion mass spectrometry as a technique for materials analysis. This approach is developing into one of the most effective methods of characterizing the composition and chemical state of the surface and sub-surface layers of solid materials. The first three chapters introduce the basic physical and chemical principles involved and the theories which have been proposed to explain the process. Subsequent chapters describe the instrumental components of the SIMS apparatus, the use of SIMS as an analytical tool, and the development of the techniques of sputtered neutral mass spectrometry and laser microprobe and plasma desorption mass spectrometry. Many practical examples are featured to illustrate the application of SIMS to real problems, possible pitfalls are pointed out, and data of use to analysts are collected in appendices. The book is a practical guide suitable for scientists in all fields who wish to use this valuable analytical technique.