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Slices Of Humanity
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Book Synopsis Simulating Humans by : Norman I. Badler
Download or read book Simulating Humans written by Norman I. Badler and published by Oxford University Press, USA. This book was released on 1993-09-02 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: The area of simulated human figures is an active research area in computer graphics, and Norman Badler's group at the University of Pennsylvania is one of the leaders in the field. This book summarizes the state of the art in simulating human figures, discusses many of the interesting application areas, and makes some assumptions and predictions about where the field is going.
Book Synopsis Atlas of the Visible Human Male by : Victor M. Spitzer
Download or read book Atlas of the Visible Human Male written by Victor M. Spitzer and published by Jones & Bartlett Learning. This book was released on 1998 with total page 550 pages. Available in PDF, EPUB and Kindle. Book excerpt: Atlas of the Visible Human reference text completely catalogs the internal human male in a way never before possible. The latest in high-definition computers were used to compile cuts taken from one cadaver into three different perspectives: transverse, coronal, and sagittal. This text is an invaluable reference for professionals, students, and anyone interest in the fascinating detail of the human body.
Book Synopsis Railroad Trainmen's Journal by : Daniel L. Cease
Download or read book Railroad Trainmen's Journal written by Daniel L. Cease and published by . This book was released on 1899 with total page 1238 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Digital Human Modeling by : Vincent D. Duffy
Download or read book Digital Human Modeling written by Vincent D. Duffy and published by Springer. This book was released on 2007-08-24 with total page 1083 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the First International Conference on Digital Human Modeling, DHM 2007, held in Beijing, China in July 2007. The papers thoroughly cover the thematic area of digital human modeling, addressing the following major topics: shape and movement modeling and anthropometry, building and applying virtual humans, medical and rehabilitation applications, as well as industrial and ergonomic applications.
Book Synopsis Three Dimensional Human Organotypic Models for Biomedical Research by : Fabio Bagnoli
Download or read book Three Dimensional Human Organotypic Models for Biomedical Research written by Fabio Bagnoli and published by Springer Nature. This book was released on 2021-05-20 with total page 265 pages. Available in PDF, EPUB and Kindle. Book excerpt: This edited volume discusses the application of very diverse human organotypic models in major areas of biomedical research. The authors lay a main focus on infectious diseases, cancer, allergies, as well as drug/vaccine discovery and toxicology studies. Representing a valid alternative to laboratory animals, these models are relevant for most areas of translational research. As the contemporary research shows, many human tissues can today be cultivated in vitro and used for several research objectives. This book provides an unprecedented overview of recent developments in an exciting field of research methodology. It is a reference guide for scientists in both academia and industry. Readers can update their knowledge and get hands-on recommendations on how to set up an organotypic model in their lab. Chapters 'Progress on Reconstructed Human Skin Models for Allergy Research and Identifying Contact Sensitizers' and 'Human Organotypic Models for Anti-infective Research' of this book are available open access under a CC BY 4.0 license at link.springer.com.
Book Synopsis Encyclopedia of Human Relationships by : Harry T. Reis
Download or read book Encyclopedia of Human Relationships written by Harry T. Reis and published by SAGE. This book was released on 2009-03-25 with total page 1905 pages. Available in PDF, EPUB and Kindle. Book excerpt: This encyclopedia provides a structure to understand the essential rudiments of human behaviour and interpersonal relationships
Book Synopsis Talker Quality in Human and Machine Interaction by : Benjamin Weiss
Download or read book Talker Quality in Human and Machine Interaction written by Benjamin Weiss and published by Springer. This book was released on 2019-07-13 with total page 155 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book discusses subjective ratings of quality and preference of unknown voices and dialog partners – their likability, for example. Human natural and artificial voices are studied in passive listening and interactive scenarios. In this book, the background, state of research, and contributions to the assessment and prediction of talker quality that is constituted in voice perception and in dialog are presented. Starting from theories and empirical findings from human interaction, major results and approaches are transferred to the domain of human-computer interaction (HCI). The main objective of this book is to contribute to the evaluation of spoken interaction in humans and between humans and computers, and in particular to the quality subsequently attributed to the speaking system or person based on the listening and interactive experience. Provides a comprehensive overview of research in evaluation of speakers and dialog partners; Presents recent results on the relevance of a first passive and interactive impression; Includes human and HCI evaluation results from a communicative perspective.
Book Synopsis Human-based Systems for Translational Research by : Robert Coleman
Download or read book Human-based Systems for Translational Research written by Robert Coleman and published by Royal Society of Chemistry. This book was released on 2014-12-08 with total page 297 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a history and discussion of the use of human tissues as an alternative to animal-based testing for assessing the efficacy and safety of new medicines. Beginning by providing a historical background to animal-based testing, this text then describes in detail the issues relating to access to human cells and tissue and the rules and regulations governing their use. The book illustrates what is currently possible in humanising medicines research and development, and suggests more rational and reliable means of developing safe and effective drugs for the future than those on which we currently rely. Early chapters establish the need to generate more data in human-derived test systems, and the need for resources such as tissue banks and standardised processes whilst highlighting the barriers that have prevented such developments so far. Subsequent chapters explore the alternatives to current animal toxicology studies, including stem cells and computational models, with balanced views of the technical challenges and opportunities these offer. In addition, useful information on computational methods and pharmacokinetics are included. This book is an essential read for anyone engaged in translational drug discovery who wishes to consolidate their understanding and broaden their awareness of the key issues involved in accessing primary human tissue and the advantages of doing so.
Book Synopsis Drug Discovery and Evaluation: Safety and Pharmacokinetic Assays by : Franz J. Hock
Download or read book Drug Discovery and Evaluation: Safety and Pharmacokinetic Assays written by Franz J. Hock and published by Springer Nature. This book was released on 2025-02 with total page 2751 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many aspects of drug safety have become an outstanding and even persistent issue and may occur during the process of both drug discovery and development. Until 15 years ago, drug discovery and evaluation was primarily a sequential process starting with the selection of the most pharmacologically active compound from a series of newly synthesized small molecule chemical series by means of distinctive pharmacological assays. Safety aspects were addressed by evaluation of the selected compound at high doses in a series of specific studies directed at indications other than the intended indication of the new compound. These tests are then followed by pharmacokinetic studies, which are primarily conducted to confirm whether the selected compound possesses a suitable half-life for sufficient exposure and efficacy and, whether it has the desired properties specificity to the intended route of administration. Safety aspects relied predominantly on the conduct of single and repeat toxicologydose studies, which inform changes in organ structure rather than organ function. Both toxicological and pharmacokinetic studies are adapted to the progress of studies in clinical pharmacology and clinical trials. The new edition of this well and broadly accepted reference work contains several innovative and distinguished chapters. This "sequential" strategy has been abandoned with this new version of the book for several reasons: - Of the possible multitude of negative effects that novel drugs may impart on organ function, e.g. ventricular tachy-arrhythmia, many are detected too late in non-clinical studies to inform clinicians. On the other hand, negative findings in chronic toxicity studies in animals may turn out to be irrelevant for human beings. - New scientific approaches, e.g. high-throughput screening, human pluripotent stem cells, transgenic animals, knock-out animals, in silico models, pharmaco-genomics and pharmaco-proteomics, as well as Artificial Intelligence (AI) methods offered new possibilities. - There are several examples, that show that the "druggability" of compounds was considerably underestimated when the probability of success of a new project was assessed. The success rate in the pharmaceutical industry and the introduction of new chemical entities to the market per year dropped dramatically, whereas the development time for a new compound increased, sometimes exceeding the patent protection. Research and development scientists, involving the following changes, therefore adopted a change of strategy: - Parallel instead of sequential involvement of the various disciplines (multidimensional compound optimization). - The term "Safety Pharmacology" was coined. The International Conference on Harmonization (ICH) founded a Safety Pharmacology Working Group and the Safety Pharmacology Society (SPS) was launched. The discipline provided for evaluation, development and validation of a multitude of safety tests outlined in the 'Core Battery of Studies'. - Characterizing the exposure profile of a drug by conducting pharmacokinetic studies that evaluates the absorption, distribution, metabolism and excretion should to be investigated at an early stage of development as results contribute to the selection of a compound for further development. Advancements in Toxicology were achieved by the introduction of new methods, e.g., in silico methods, genetic toxicology, computational toxicology and AI. The book is a landmark in the continuously changing world of drug research and developments. As such, it is essential reading for many groups: not only for all students of pharmacology and toxicology but also for industry scientists and physicians, especially those involved in clinical trials of drugs, and for pharmacists who must know the safety requirements of drugs. The book is essential for scientists and managers in the pharmaceutical industry who are involved in drug discovery, drug development and decision making in the development process. In particular, the book will be of use to government institutions and committees working on official guidelines for drug evaluation worldwide.
Author :Donald G. Montemurro Publisher :New York : Oxford University Press ISBN 13 :9780195049268 Total Pages :212 pages Book Rating :4.0/5 (492 download)
Book Synopsis The Human Brain in Dissection by : Donald G. Montemurro
Download or read book The Human Brain in Dissection written by Donald G. Montemurro and published by New York : Oxford University Press. This book was released on 1988 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human Neuroanatomy: A Text, Brain Atlas, and Laboratory Dissection Guidehas been substantially changed and updated from a previous edition entitled The Human Brain in Dissection published in 1988 and accordingly has been re-titled. The last 20 years have seen a significant shift in the way anatomy and its sub-disciplines like neuroanatomy are taught in both undergraduate and graduate neuroscience courses; not only has the time allocated for these courses been reduced, but the teaching methodologies have become more focused and specific due to time constraints. As reported by Drake et. al., "Medical education in the anatomical sciences: the winds of change continue to blow" (Anat. Sci. Educ., 2: 253-259, 2009), we have seen an overall drop in the total number of lecture hours and laboratory hours since the last survey done of medical curricula in 2002.Human Neuroanatomyhas been reconstructed to appeal to just these changes: courses with a lab/dissection component as well as those without will find this guide the perfect teaching tool to understand human neuroanatomy. With these limitations in mind and to better meet current requirements the authors have expanded the textural content in this new edition and separated it entirely from the dissection instructions which have been retained. The "Laboratory Exercise" as it is now designated stands alone in a highlighted box in each chapter. It outlines what is to be accomplished during a given session using pre-dissected specimens and/or appropriate models or by exposing them in a dissection. Clear step by step procedural instructions are provided and important structures to be seen are highlighted. The dissection sequence laid out in the chapters is a progressive one requiring only a single wet specimen and ideally completed in two hour periods. Students who do not have the opportunity to dissect, however may simply skip these paragraphs. In this 3rd edition of the book many new illustrations have been added to better depict the salient features of the brain at various stages of dissection and to facilitate understanding the subject matter. Labeling of some illustrations has changed and others have been replaced. All are amply referenced to the text and to the laboratory exercises and are intended to assist with or be used in lieu of dissection. New also in this edition is a section of clinically-relevant notes as well as USMLE type multiple-choice questions added in separate sections at the end of each chapter. These quiz type questions provide students with a means of assessing their understanding of the subject matter in each chapter and an indication of how their knowledge might be tested. And finally, an atlas of 62 labelled brain sections in four different planes, at the end of the book, has been retained. CT scans and M.R. images that correspond as closely as possible to the anatomic section are included. Comprehensive and conciseHuman Neuroanatomy: A Text, Brain Atlas, and Laboratory Dissection Guideis an invaluable guide to assist medical, dental and allied health science students understand nervous system structure, function and disease.
Book Synopsis Biological Reactive Intermediates IV by : Charlotte M. Witmer
Download or read book Biological Reactive Intermediates IV written by Charlotte M. Witmer and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 848 pages. Available in PDF, EPUB and Kindle. Book excerpt: The finding that chemicals can be metabolically activated to yield reactive chemical species capable of covalently binding to cellular macromolecules and the concept that these reactions could initiate toxicological and carcinogenic events stimulated a meeting by a small group of toxicologists at the University of Turku, in Finland, in 1975 (Jollow et al. , 1977). The growing interest in this field of research led to subsequent symposia at the University of Surrey, in England in 1980 (Snyder et al. , 1982), and the University of Maryland in the U. S. A. in 1985 (Kocsis et al. , 1986). The Fourth International Symposium on Biological Reactive Intermediates was hosted by the Center for Toxicology at the University of Arizona and convened in Tucson, Arizona, January 14-17, 1990. Over 300 people attended. There were 60 platform presentations by invited speakers, and 96 volunteer communications in the form of posters were offered. These meetings have grown from a small group of scientists working in closely related areas to a major international series of symposia which convene every five years to review, and place in context, the latest advances in our understanding of the formation, fate and consequences of biological reactive intermediates. The Organizing Committee: Allan H. Conney, Robert Snyder (Co-chairman), and Charlotte M. Witmer (Rutgers University, Piscataway, NJ), David J. Jollow Co chairman) (Medical University, South Carolina, Charleston, SC), 1. Glenn Sipes (Co chairman) (University of Arizona, Tucson, AZ), James J. Kocsis and George F.
Download or read book Drug Toxicity written by Cam E. Vellotis and published by Nova Publishers. This book was released on 2008 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: The systemic effects of a drug that are related to the overall level of the medication in the bloodstream. Drug toxicity may occur with overdosage of a medication, accumulation of the drug in the body over time or the inability of the patients body to eliminate the drug. This book presents recent and important research in the field.
Download or read book Epilepsy Surgery written by Hans Lüders and published by Lippincott Williams & Wilkins. This book was released on 2001-01-01 with total page 1152 pages. Available in PDF, EPUB and Kindle. Book excerpt: The thoroughly revised and updated Second Edition of this landmark work is the most comprehensive and current reference on the surgical treatment of the epilepsies. More than 100 invited experts from around the world present a global view of contemporary approaches to presurgical evaluation, surgical treatment, and postsurgical assessment. This edition provides detailed information on the vital role of structural and functional neuroimaging in presurgical evaluation and surgical planning. Noted experts offer up-to-date patient selection guidelines and explain current concepts of intractability. The book details the most effective surgical techniques, presents extensive data on surgical outcome, and discusses strategies for preventing and managing complications. More than 500 illustrations complement the text. An appendix section includes protocols and outcome statistics from over 50 leading epilepsy surgery centers.
Book Synopsis Human-in-the-loop System Design and Control Adaptation for Behavior-Assistant Robots by : Yuquan Leng
Download or read book Human-in-the-loop System Design and Control Adaptation for Behavior-Assistant Robots written by Yuquan Leng and published by Frontiers Media SA. This book was released on 2024-06-03 with total page 134 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the progress and development of human-robot systems, the coordination among humans, robots, and environments has become increasingly sophisticated. In this Research Topic, we focus on an important field in robotics and automation disciplines, which is commonly defined as behavior-assistant robots. The scope includes but is not limited to: (1) rehabilitation assistive devices, such as rigid/soft exoskeletons, prosthetic systems, orthoses, and intelligent wheelchairs; (2) intelligent medical systems, such as endoscopic robots, surgical robots, and the navigation systems; (3) industrial application devices, such as collaborative manipulators, load-bearing exoskeletons, supernumerary robotic limbs; (4) intelligent domestic devices, such as mobile robots, elderly-care robots, walking-aids robots and so on. The emergence of robot-assisted daily behaviors, based on aforementioned devices, is gradually becoming part of our social lives, which can improve weak motor abilities, enhance physical functionalities, and enable various other benefits.
Book Synopsis Investigating the human brainstem with structural and functional MRI by : Florian Beissner
Download or read book Investigating the human brainstem with structural and functional MRI written by Florian Beissner and published by Frontiers E-books. This book was released on 2014-07-30 with total page 93 pages. Available in PDF, EPUB and Kindle. Book excerpt: The brainstem is one of the least understood parts of the human brain despite its prime importance for the maintenance of basic vital functions. Owing to its role as a relay station between spinal cord, cerebellum and neocortex, the brainstem contains vital nodes of all functional systems in the central nervous system, including the visual, auditory, gustatory, vestibular, somatic and visceral senses, and the somatomotor as well as autonomic nervous systems. While the brainstem has been extensively studied in animals using invasive methods, human studies remain scarce. Magnetic resonance imaging (MRI) as a non-invasive and widely available method is one possibility to access the brainstem in humans and measure its structure as well as function. The close vicinity of the brainstem to large arteries and ventricles and the small size of the anatomical structures, however, place high demands on imaging as well as data analysis methods. Nevertheless, the field of brainstem-(f)MRI has significantly advanced in the past few years, largely due to the development of several new tools that facilitate studying this critical part of the human brain. Within this scope, the goal of this Research Topic is to compile work representing the state of the art in functional and structural MRI of the human brainstem.
Book Synopsis Encyclopedia of Basic Epilepsy Research by :
Download or read book Encyclopedia of Basic Epilepsy Research written by and published by Academic Press. This book was released on 2009-05-27 with total page 1853 pages. Available in PDF, EPUB and Kindle. Book excerpt: As a truly translational area of biomedical investigation, epilepsy research spans an extraordinary breadth of subjects and involves virtually every tool that modern neuroscience has at its disposal. The Encyclopedia of Basic Epilepsy Research provides an up to date, comprehensive reference for all epilepsy researchers. With an expert list of authors, the encyclopedia covers the full spectrum of research activities from genes and molecules to animal models and human patients. The encyclopedia's electronic format also provides unparalleled access to frequent updates and additions, while the limited edition print version provides another option for owning this content. The Encyclopedia of Basic Epilepsy Research is an essential resource for researchers of all levels and clinicians who study epilepsy. The only comprehensive reference for basic research and current activities in epilepsy Electronic format provides fast and easy access to updates and additions, with limited print version available as well Contains over 85 articles, all written by experts in epilepsy research
Book Synopsis New Advances in Virtual Humans by : Nadia Magnenat-Thalmann
Download or read book New Advances in Virtual Humans written by Nadia Magnenat-Thalmann and published by Springer. This book was released on 2008-09-03 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book, various aspects of cognitive and emotional behaviour is described. In chapter one, a state of the art introduction to VH is presented and the associated research is given. In Chapter 2, cognitive and emotions processes are described. A Comprehensive context model for multi-party interactions with the VH is given in the next chapter. Finally, it is very important to model the socializing of groups of virtual humans. This is discussed in Chapter 4. The automatic modelling of expressions for VH is described in Chapter 5. The last chapter gives a case study of an intelligent kios avatar and its usability. This book gives examples of some advances that enable VH to behave intelligently. It provides an overview of these research problems and some unsolved problems.
