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Skeletal Metastases
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Book Synopsis Metastatic Bone Disease by : R. Lor Randall
Download or read book Metastatic Bone Disease written by R. Lor Randall and published by Springer. This book was released on 2015-12-01 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing an integrated approach to the diagnosis and management of patients with metastatic bone disease (MBD), this comprehensive text combines discussion of the pathobiology of the disease with the latest oncological and orthopedic treatment modalities. After opening with an examination of the epidemiology and impact of MBD, the biology of bone metastases are discussed, along with considerations of the tissue of origin. Evaluation, biopsy and medical therapy, including metabolic agents and bio targeting. The heart of the book presents oncological approaches (supportive, radiation and interventional) and principles of orthopedic surgical oncology, with subsequent chapters covering specific anatomy, from the pelvis to the lower extremity and the spine. Chapters on emerging surgical technology and future directions conclude the text and redefine an integrated approach to patient care. Taken together, Metastatic Bone Disease is an excellent resource for orthopedic surgeons and cancer specialists alike.
Book Synopsis Metastatic Bone Disease by : Ingo J. Diel
Download or read book Metastatic Bone Disease written by Ingo J. Diel and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Metastatic Bone Disease: Fundamental and Clinical Aspects" is an expanded version of a workshop on bone metastases which was held in Heidelberg, Germany, in April 1993. Bone metastases very often develop from malignant tumors and lead to complications which considerably diminish the quality of life of the patient. Bone pain, pathological fractures, and hypercalcemic syndrome should be recognized and treated ear- ly, so as to prevent any further morbidity and immobilizati- on. Antiosteolytic substances such as biophosphonate can supplement the established palliative and supportive thera- pies. Highly qualified basic researchers and clinicians in pathophysiology, diagnosis, and treatment of metastatic bone disease have contributed to this book, providing a good overview ofpresent knowledge and research. The book will be of interest not only to specialists, but also to any physi- cian interested in oncology.
Download or read book Bone Cancer written by Dominique Heymann and published by Academic Press. This book was released on 2021-09-23 with total page 1080 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bone Cancer: Bone Sarcomas and Bone Metastases - From Bench to Bedside, Third Edition comprehensively investigates key discoveries in the field of bone biology. New aspects of bone cancer biology are treated in new chapters covering exosomes, autophagy, and metabolism. These have led to the development of entirely new areas for investigation, such as therapies which combine surgery and biological approaches. The Third Edition expands on the original overview of bone cancer development (physiology and pathophysiology), with 40% new material. Each chapter has been written by internationally recognized specialists on the bone cancer microenvironment, bone metastases, osteoclast biology in bone cancer, proteomics, bone niche, circulating tumor cells, and clinical trials. Given the global prevalence of breast and prostate cancers, knowledge of bone biology has become essential for everyone within the medical and cancer research communities. Bone Cancer: Bone Sarcomas and Bone Metastases - From Bench to Bedside continues to offer the only translational reference to cover all aspects of primary bone cancer and bone metastases. This revision opens the door to myeloma with two short chapters dedicated to this bone-associated disease. - Covers the broad field of bone sarcomas and bone metastases from basic research to clinical approaches - Presents comprehensive and translational overview of biological and clinical aspects of bone cancers, discussing pathophysiology from genetic and molecular levels using the most recent evidence - Provides a common language for cancer researchers, bone biologists, oncologists, and radiologists to discuss bone tumors and how bone cancer metastases affects each major organ system - Offers insights to research clinicians (oncologists and radiologists) into understanding the molecular basis of bone cancer, leading to more well-informed diagnoses and treatment of tumors and metastases - Offers insights to bone biologists into how clinical observations and practices can feed back into the research cycle and, therefore, can contribute to the development of more targeted genomic and proteomic assays
Download or read book Bone Cancer written by Dominique Heymann and published by Academic Press. This book was released on 2009-08-20 with total page 501 pages. Available in PDF, EPUB and Kindle. Book excerpt: The epidemiological and clinical importance of bone metastasis has long been recognized, but the past decade has seen an explosion in the fields of bone biology and bone cancer research. This period of time has been marked by a number of key discoveries that have led to the opening up of entirely new areas for investigation as well as new therapies which combine surgery and biological therapeutic approaches.Bone is a common site of cancer metastases - cancer cells commonly develop in bone and spread to other organ systems through the bloodstream. For example, the incidence of bone metastases in breast and prostate cancers is 70%, whereas it is only 30 to 40% in metastatic lung cancer. In clinical terms, bone metastases have substantial negative effects on a patient's quality of life and are a main cause of patient mortality. Given the global prevalence of breast and prostate cancers, knowledge of bone biology has become essential for the medical and cancer research communities. This book provides, all in one resource, the most recent data on bone cancer development (cellular and molecular mechanisms), genomic and proteomic analyses, clinical analyses (histopathology, imaging, pain monitoring), as well as new therapeutic approaches and clinical trials for primary bone tumors and bone metastases. Feature - Presents a comprehensive, translational source for all aspects of bone cancer in one reference work - Bone cancer experts (from all areas of research and practice) take readers from the bench research (cellular and molecular mechanism), through genomic and proteomic analysis, all the way to clinical analysis (histopathology and imaging) and new therapeutic approaches. - Clear presentation by bone biologists of the cellular and molecular mechanisms underlying bone tumors and bone cancer metastasis as well as the genomic and proteomic assays used in detecting cancer within given organ systems - - Clear presentation by oncologists and radiologists of how histopathology, imaging, and pain monitoring can lead to new therapeutic approaches Benefit - Saves researchers and clinicians time in quickly accessing the very latest details on a broad range of bone cancer issues, as opposed to searching through thousands of journal articles. - Provides a common language for cancer researchers, bone biologists, oncologists, and radiologists to discuss bone tumors and how bone cancer metastases affects each major organ system - Correct diagnosis (and therefore correct treatment) of cancer depends on a strong understanding of the molecular basis for the disease – both oncologists and radiologists will benefit - Bone biologists will gain insight into how clinical observations and practices can feed back into the research cycle and will, therefore, be able to develop more targeted genomic and proteomic assays
Download or read book Bone Tumors written by Jaime Paulos and published by Springer Nature. This book was released on 2021-07-15 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews the latest techniques for diagnostics and treatments specific to bone and soft tissue tumors. It focuses on imaging and classification of the bone and soft tissue tumors and how histology and cytogenetic aspects can be used to identify tumors. Each chapter focuses on a specific type of tumor, providing a concise overview of relevant information on their characteristics along with the latest surgical and medical treatments available. Bone Tumors: Diagnosis and Therapy Today is a concise guide to successfully identifying and treating bone and soft tissue tumors, making it a valuable resource for practicing medical professionals and trainees who encounter these patients in their day-to-day practice.
Book Synopsis Stereotactic Body Radiation Therapy by : Simon S. Lo
Download or read book Stereotactic Body Radiation Therapy written by Simon S. Lo and published by Springer Science & Business Media. This book was released on 2012-08-28 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stereotactic body radiation therapy (SBRT) has emerged as an important innovative treatment for various primary and metastatic cancers. This book provides a comprehensive and up-to-date account of the physical/technological, biological, and clinical aspects of SBRT. It will serve as a detailed resource for this rapidly developing treatment modality. The organ sites covered include lung, liver, spine, pancreas, prostate, adrenal, head and neck, and female reproductive tract. Retrospective studies and prospective clinical trials on SBRT for various organ sites from around the world are examined, and toxicities and normal tissue constraints are discussed. This book features unique insights from world-renowned experts in SBRT from North America, Asia, and Europe. It will be necessary reading for radiation oncologists, radiation oncology residents and fellows, medical physicists, medical physics residents, medical oncologists, surgical oncologists, and cancer scientists.
Book Synopsis The Biology of Skeletal Metastases by : Evan T. Keller
Download or read book The Biology of Skeletal Metastases written by Evan T. Keller and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: - National Cancer Institure Budget is encouraging research in order to develop a better understanding of metastasis of cancer to the bone - Provides the reader with comprehensive reviews written by well known experts on related topics
Book Synopsis Management of Bone Metastases by : Vincenzo Denaro
Download or read book Management of Bone Metastases written by Vincenzo Denaro and published by Springer. This book was released on 2018-07-25 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: This highly informative book provides a comprehensive, up-to-date and practical reference for daily clinical practice in the management of patients affected by bone metastases. Written by renowned orthopedic surgeons and leading doctors in the respective fields of expertise, it offers a transversal review of the current medical and surgical treatments to allow a real interdisciplinary approach to the oncologic patient according to the highest current standards. The book illustrates all the fundamental medical treatments for metastatic bone diseases and provides an overview of pathology issues related to this condition. An entire section is devoted to main different methods of patients approach. It also provides guidance on all current surgical procedures and minimally invasive treatment techniques. Using a common language and recognizing the different osteoncologic competences, this work allows surgeons, oncologists, radiologists, pathologists and physiatricians to update their expertise and broaden their understanding of how a real team approach can improve the management of these oncology patients.
Book Synopsis Spinal Instability by : Robert N.N. Holtzman
Download or read book Spinal Instability written by Robert N.N. Holtzman and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 537 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this volume, world authorities on spinal surgery from the fields of Neurosurgery, Orthopaedic Surgery, and Neuroscience present current data on the basic science and clinical management of the unstable spine. Unique to this book: a frank presentation of controversies in the field.
Book Synopsis Bone and Soft Tissue Tumors by : Mario Campanacci
Download or read book Bone and Soft Tissue Tumors written by Mario Campanacci and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 1275 pages. Available in PDF, EPUB and Kindle. Book excerpt: A systematic treatise of tumors and tumor-like lesions occurring in bone and soft tissues. The introductory chapter presents the terminology, the basic principles for classification and diagnosis, the general principles of imaging, biopsy and histology, the staging system and evaluation of the surgical margins, the general principles of curettage, local adjuvants, en bloc resection and reconstruction, chemotherapy and radiotherapy. Each pathologic entity is described according to its epidemiology, localization, symptoms, imaging, gross pathology, histopathology, histogenesis and pathogenesis, differential diagnosis, course and stage, treatment and prognosis.
Book Synopsis Exercise Oncology by : Kathryn H. Schmitz
Download or read book Exercise Oncology written by Kathryn H. Schmitz and published by Springer Nature. This book was released on 2020-05-04 with total page 438 pages. Available in PDF, EPUB and Kindle. Book excerpt: This groundbreaking book presents a unique and practical approach to the evolving field of exercise oncology - the study of physical activity in the context of cancer prevention and control. Presenting the current state of the art, the book is sensibly divided into four thematic sections. Following an opening chapter presenting an overview and timeline of exercise oncology, the chapters comprising part I discuss primary cancer prevention, physical activity and survivorship, and the mechanisms by which these operate. Diagnosis and treatment considerations are discussed in part II, including prehabilitation, exercise during surgical recovery, infusion and radiation therapies, and treatment efficacy. Post-treatment and end-of-life care are covered in part III, including cardio-oncology, energetics and palliative care. Part IV presents behavioral, logistical and policy-making considerations, highlighting a multidisciplinary approach to exercise oncology as well as practical matters such as reimbursement and economics. Written and edited by experts in the field, Exercise Oncology will be a go-to practical resource for sports medicine clinicians, family and primary care physicians, oncologists, physical therapy and rehabilitation specialists, and all medical professionals who treat cancer patients.
Book Synopsis Diagnosis of Musculoskeletal Tumors and Tumor-like Conditions by : Piero Picci
Download or read book Diagnosis of Musculoskeletal Tumors and Tumor-like Conditions written by Piero Picci and published by Springer Nature. This book was released on 2019-12-06 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, now in a second revised edition, casts light on the often complex diagnosis of musculoskeletal tumors and tumor-like conditions by drawing on the experience of the Rizzoli Orthopedic Institute during more than 100 years of treatment and research in the field. The different entities are described from a multidisciplinary perspective, highlighting clinical, radiological, and histological correlations. Particular emphasis is placed on differential diagnosis, which often needs to take into account nontumoral conditions. The recent identification of further significant biological and genetic features, and the impact of these discoveries on the classification of round cell tumors, vascular lesions, and spindle/pleomorphic entities in bone, is also extensively discussed. The Rizzoli case archive dates back to September 1900 and contains the original material relating to more than 29,000 bone lesions and 11,000 soft tissue lesions. It is a fabulously rich resource, and this book will be invaluable for pathologists, radiologists, and clinicians at all levels of experience.
Book Synopsis Clinical Oncology by : Martin D. Abeloff
Download or read book Clinical Oncology written by Martin D. Abeloff and published by . This book was released on 2000 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: A must-have reference, this new edition provides practical information on treatment guidelines, details of diagnosis and therapy, and personal recommendations on patient management from experts in the field. Consistently formatted chapters allow for a user-friendly presentation for quick access of key information by the practicing clinician. Completely updated, this new edition includes all of the latest developments in treatment strategies of medical, surgical and radiation oncologists.
Book Synopsis Principles of Bone Biology by : John P. Bilezikian
Download or read book Principles of Bone Biology written by John P. Bilezikian and published by Academic Press. This book was released on 2008-09-29 with total page 2074 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles of Bone Biology provides the most comprehensive, authoritative reference on the study of bone biology and related diseases. It is the essential resource for anyone involved in the study of bone biology. Bone research in recent years has generated enormous attention, mainly because of the broad public health implications of osteoporosis and related bone disorders. - Provides a "one-stop" shop. There is no need to search through many research journals or books to glean the information one wants...it is all in one source written by the experts in the field - The essential resource for anyone involved in the study of bones and bone diseases - Takes the reader from the basic elements of fundamental research to the most sophisticated concepts in therapeutics - Readers can easily search and locate information quickly as it will be online with this new edition
Book Synopsis Prevention of Bone Metastases by : Markus Joerger
Download or read book Prevention of Bone Metastases written by Markus Joerger and published by Springer Science & Business Media. This book was released on 2012-01-05 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bone metastases continue to be a major cause of morbidity in cancer patients, but improved understanding of the biology of bone metastases has led to the identification of drugs that are of potential value in not only their treatment but also their prevention. This book, written by recognized experts in the field, provides a detailed overview of current knowledge on this subject. One important focus of the book is the efficacy of bisphosphonates in preventing bone metastases in patients with breast, lung, and prostate cancer and disease progression in cases of multiple myeloma. The combined use of bisphosphonates and cytostatics is also discussed, with a report on first clinical data. Further topics addressed include the significance of the bone microenvironment, special issues in the elderly patient, the use of bone turnover markers, and initial findings obtained with denosumab.
Book Synopsis Hypercalcemia of Malignancy by : Friedhelm Raue
Download or read book Hypercalcemia of Malignancy written by Friedhelm Raue and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hypercalcemia is the most common life-threatening metabolic disorder associated with cancer. The pathophysiological, epidemiological and clinical aspects of hypercalcemia of malignancy are presented in this issue, with a focus on the recently discovered humoral factor responsible for the development of hypercalcemia. With a better understanding of the pathophysiology of this condition and the development of new potent drugs, capable of inhibiting bone resorption, especially bisphosphonates, the clinician will be more successful in correcting hypercalcemia in the great majority of patients.
Book Synopsis Bone Metastases by : Dimitrios Kardamakis
Download or read book Bone Metastases written by Dimitrios Kardamakis and published by Springer Science & Business Media. This book was released on 2009-07-21 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bone Metastases: A Translational and Clinical Approach serves as both an introductory and reference book focusing on the field of metastatic bone disease. Featuring contributions from experts in the field, this volume: describes the molecular and cellular mechanisms involved in the formation of bone metastases, comments on the role of angiogenesis, presents the newer advances made in the understanding of the clinical picture and symptoms of patients, analyses the role of bone markers in research and clinical practice deals with all aspects of imaging modalities applied for the detection and evaluation of bone metastases. This volume also covers the use of radiotherapy, surgery and systemic treatments for the management of metastatic bone disease and new therapeutic approaches. Moreover it may also serve as a guide for the clinical and therapeutic management of patients with metastatic bone disease. Overall this volume presents a thorough overview of all aspects of metastatic bone disease and provides a comprehensive and concise information resource for medical researchers, oncologists, orthopaedic surgeons and clinicians.
