Sirolimus-Eluting Stents

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Publisher : CRC Press
ISBN 13 : 9781841844923
Total Pages : 210 pages
Book Rating : 4.8/5 (449 download)

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Book Synopsis Sirolimus-Eluting Stents by : Patrick W. Serruys

Download or read book Sirolimus-Eluting Stents written by Patrick W. Serruys and published by CRC Press. This book was released on 2004-11-29 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recently, sirolimus-eluting stents implantation has been shown to decrease restenosis markedly in selected patients. Nonetheless, the effects of SES implantation in complex, unselected patients, such as those commonly treated in daily practice ('the real world'), remains largely unknown. This book comprehensively evaluates the impact of SES implantation on the outcomes of patients treated in the real world of interventional cardiology. The authors have evaluated in detail the short- and long-term outcomes of several high-risk subsets not currently included in randomized trials. While it is specific to sirolimus, the book covers the major competing drug eluting stents, including paclitaxel.

Bioresorbable Scaffolds

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Publisher : CRC Press
ISBN 13 : 1498779778
Total Pages : 533 pages
Book Rating : 4.4/5 (987 download)

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Book Synopsis Bioresorbable Scaffolds by : Yoshinobu Onuma

Download or read book Bioresorbable Scaffolds written by Yoshinobu Onuma and published by CRC Press. This book was released on 2017-10-02 with total page 533 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on the coronary bioresorbable scaffold, a new interventional treatment for coronary artery disease, differentiated from a permanent metallic stent. The book provides an overview of the technology including non-clinical studies and clinical evidences in order to help clinicians understand the appropriate application of the technology and the optimal techniques of implantation. It covers the basics of bioresorbable scaffolds; bench test results; preclinical studies; clinical evidences; and tips and tricks of implantation.

Unrestricted Utilization of Sirolimus-eluting Stents in the "Real World": the Rapamycin-eluting Stent Evaluation at Rotterdam Cardiology Hospital (RESEARCH) Registry

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Publisher :
ISBN 13 : 9789077595282
Total Pages : 181 pages
Book Rating : 4.5/5 (952 download)

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Book Synopsis Unrestricted Utilization of Sirolimus-eluting Stents in the "Real World": the Rapamycin-eluting Stent Evaluation at Rotterdam Cardiology Hospital (RESEARCH) Registry by : Pedro A. Lemos Lemos Neto

Download or read book Unrestricted Utilization of Sirolimus-eluting Stents in the "Real World": the Rapamycin-eluting Stent Evaluation at Rotterdam Cardiology Hospital (RESEARCH) Registry written by Pedro A. Lemos Lemos Neto and published by . This book was released on 2004 with total page 181 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Efficacy of Restricted Use of Sirolimus-eluting Stents in "Real Life"

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Publisher :
ISBN 13 :
Total Pages : 42 pages
Book Rating : 4.:/5 (868 download)

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Book Synopsis Efficacy of Restricted Use of Sirolimus-eluting Stents in "Real Life" by : Philipp Schweizer

Download or read book Efficacy of Restricted Use of Sirolimus-eluting Stents in "Real Life" written by Philipp Schweizer and published by . This book was released on 2013 with total page 42 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Handbook of Drug-Eluting Stents

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Publisher : CRC Press
ISBN 13 : 9781841841328
Total Pages : 336 pages
Book Rating : 4.8/5 (413 download)

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Book Synopsis Handbook of Drug-Eluting Stents by : Patrick W. Serruys

Download or read book Handbook of Drug-Eluting Stents written by Patrick W. Serruys and published by CRC Press. This book was released on 2005-06-14 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past few years, the focus in interventional cardiology research has centered on reducing restenosis with the use of antiproliferative pharmacological agents. The use of these drugs, hitherto, has failed, most probably because of low active drug levels at the target site. This problem led to the development of local drug delivery using stents, since they can serve as a reservoir for local drug administration and are in immediate contract with the coronary artery wall, thus ensuring maximum delivery of the pharmacological agent. Drug-eluting stents provide an entirely new spectrum of potential therapies for restenosis. Handbook of Drug-Eluting Stents, under the editorial direction of Patrick Serruys, one of the world's leading interventional cardiologists, and Tony Gershlick, a pioneer in the field of drug-eluting stents, provides the reader with up-to-date information on which stents and pharmacological agents in use or about to be launched, the kinetics of the drugs involved, and what the future may hold. Short Contents

Coronary Lesions

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Publisher : CRC Press
ISBN 13 : 9781853179365
Total Pages : 376 pages
Book Rating : 4.1/5 (793 download)

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Book Synopsis Coronary Lesions by : Patrick W. Serruys

Download or read book Coronary Lesions written by Patrick W. Serruys and published by CRC Press. This book was released on 2001-09-13 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: The interventional cardiologist has to tackle a diverse and complex range of coronary lesions. For this reason, the experts who compiled this volume contribute the best practices for overcoming plaque and thrombus in the coronary arteries. From simple to complicated anatomy, the direct approach to achieving optimal results is clearly described and illustrated. Each chapter focuses on a specific problem, and top quality angiograms illustrate the various coronary lesions. The editors, all experts and pioneers in the field of interventional cardiology, from stenting to myocardial revascularization, have assembled a team of internationally renowned contributors to offer their practical advice on how to approach lesions in a straight-forward, pragmatic fashion. This guide is indispensable for cardiologists and students of the field, as well as for general practitioners.

Drug-Eluting Stents

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Publisher : CRC Press
ISBN 13 : 9780203301197
Total Pages : 172 pages
Book Rating : 4.3/5 (11 download)

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Book Synopsis Drug-Eluting Stents by : Christopher J. White

Download or read book Drug-Eluting Stents written by Christopher J. White and published by CRC Press. This book was released on 2005-06-30 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt: The cure for restenosis has been the Holy Grail of interventional cardiology since the advent of coronary angioplasty in the late 1970s. The development of stents improved the durability of angioplasty, but in-stent restenosis was a major problem for patients and the physicians. To deliver drugs locally on stents that prevent restenosis is a revolutionary advance. Percutaneous revascularization technology has leaped forward, dramatically altering clinical practices, with what may be the single most important advance in the history of cardiology. There are new delivery platforms and new drugs currently being tested. Despite the continuing advancement, there was a need to collate in a single text, information on drug eluting stents for coronary disease. Chris White and colleagues have put together a logically organized text that progresses from theory to practice, and addresses pharmacologic, technical and strategic issues as they relate to the placement of coronary drug-eluting stents.

The Unrestricted Use of Paclitaxel-eluting Stents and Eirolimus-eluting Stents in the Rotterdam T-SEARCH and RESEARCH Registries: Studies on Efficacy, Safety, Stent Thrombosis, Cost Eff Ectiveness and the Future

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Author :
Publisher :
ISBN 13 : 9789085596929
Total Pages : 316 pages
Book Rating : 4.5/5 (969 download)

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Book Synopsis The Unrestricted Use of Paclitaxel-eluting Stents and Eirolimus-eluting Stents in the Rotterdam T-SEARCH and RESEARCH Registries: Studies on Efficacy, Safety, Stent Thrombosis, Cost Eff Ectiveness and the Future by : Andrew Teck Leong Ong

Download or read book The Unrestricted Use of Paclitaxel-eluting Stents and Eirolimus-eluting Stents in the Rotterdam T-SEARCH and RESEARCH Registries: Studies on Efficacy, Safety, Stent Thrombosis, Cost Eff Ectiveness and the Future written by Andrew Teck Leong Ong and published by . This book was released on 2007 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Ultrathin, Bioresorbable Polymer Sirolimus-eluting Stents Versus Thin, Durable Polymer Everolimus-eluting Stents in Patients Undergoing Coronary Revascularisation (BIOFLOW V): a Randomised Trial

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (15 download)

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Book Synopsis Ultrathin, Bioresorbable Polymer Sirolimus-eluting Stents Versus Thin, Durable Polymer Everolimus-eluting Stents in Patients Undergoing Coronary Revascularisation (BIOFLOW V): a Randomised Trial by :

Download or read book Ultrathin, Bioresorbable Polymer Sirolimus-eluting Stents Versus Thin, Durable Polymer Everolimus-eluting Stents in Patients Undergoing Coronary Revascularisation (BIOFLOW V): a Randomised Trial written by and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Bifurcation Stenting

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Publisher : John Wiley & Sons
ISBN 13 : 1444346989
Total Pages : 400 pages
Book Rating : 4.4/5 (443 download)

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Book Synopsis Bifurcation Stenting by : Ron Waksman

Download or read book Bifurcation Stenting written by Ron Waksman and published by John Wiley & Sons. This book was released on 2012-03-22 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Here is expert guidance on one of the most vexing clinical challenges faced by interventional cardiologists. Written by global thought leaders in the area and edited by two internationally-recognized pioneers in interventional cardiology, Bifurcation Stenting covers all techniques, imaging modalities, and devices in current use, including VH-IVUS and OCT. It includes practical tips/tricks from leading experts and a section of challenging cases to further illustrate the material and help readers better understand the treatment of bifurcation lesions.

Drug-Coated Balloons

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Publisher : Springer
ISBN 13 : 3319926004
Total Pages : 234 pages
Book Rating : 4.3/5 (199 download)

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Book Synopsis Drug-Coated Balloons by : Bernardo Cortese

Download or read book Drug-Coated Balloons written by Bernardo Cortese and published by Springer. This book was released on 2019-06-19 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive, up-to-date summary of drug-coated balloon (DCB) technology and the role of DCBs in the treatment of coronary and peripheral arterial disease. In addition to clear explanation of how DCBs works, readers will find an enlightening analysis of the mistakes and successes of the past decade and the emergence of the latest delivery systems, which combine a more deliverable device with much improved drug delivery to the vessel wall. The full range of current applications of DCBs are reviewed in detail, drawing on the latest scientific evidence. Due attention is paid to newer devices, with provision of technical insights and documentation of the available clinical data. Ongoing research projects, remaining technical challenges, likely future directions, and reimbursement issues are also carefully considered. This book will be a useful tool for any interventional cardiologist, interventional radiologist, or vascular surgeon who wishes to acquire a deep knowledge of this technology and its application in both coronary and peripheral interventions.

Endothelialization of sirolimus-eluting stents with slow- and extended-drug release in the porcine overstretch model

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Publisher :
ISBN 13 :
Total Pages : 4 pages
Book Rating : 4.:/5 (731 download)

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Book Synopsis Endothelialization of sirolimus-eluting stents with slow- and extended-drug release in the porcine overstretch model by : Daniela Frey

Download or read book Endothelialization of sirolimus-eluting stents with slow- and extended-drug release in the porcine overstretch model written by Daniela Frey and published by . This book was released on 2010 with total page 4 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Interventional Cardiology

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Publisher : John Wiley & Sons
ISBN 13 : 1118975960
Total Pages : 2479 pages
Book Rating : 4.1/5 (189 download)

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Book Synopsis Interventional Cardiology by : George D. Dangas

Download or read book Interventional Cardiology written by George D. Dangas and published by John Wiley & Sons. This book was released on 2016-11-28 with total page 2479 pages. Available in PDF, EPUB and Kindle. Book excerpt: Expert guidance from internationally recognized authorities, who provide clear and current updates on all aspects of interventional cardiology. This new edition; Contains a radically expanded chapter contents list presented in four clear sections; coronary interventions, interventional pharmacology, structural heart interventions, and endovascular therapy Includes 46 new chapters, including the latest advances in bioresorbable coronary stents, advanced transcatheter aortic valve replacement, MitraClip, new transcatheter mitral valve interventions, and more Chapters are templated for rapid referral, beginning with pathophysiological background and relevant pathology, moving to mechanisms of treatment, device description, procedural techniques, follow-up care, and ending with risks, contraindications and complications Multiple choice questions at the end of each chapter for self-assessment, a total of more than 400 MCQs in the book Features 19 procedural videos, hosted on a companion website

Two Year Clinical Outcome After Implantation of Sirolimus-eluting and Paclitaxel-eluting Stents in Routine Clinical Practice

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Publisher :
ISBN 13 :
Total Pages : 28 pages
Book Rating : 4.:/5 (638 download)

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Book Synopsis Two Year Clinical Outcome After Implantation of Sirolimus-eluting and Paclitaxel-eluting Stents in Routine Clinical Practice by : Alexandra Michelle Hofmann

Download or read book Two Year Clinical Outcome After Implantation of Sirolimus-eluting and Paclitaxel-eluting Stents in Routine Clinical Practice written by Alexandra Michelle Hofmann and published by . This book was released on 2009 with total page 28 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Long-term Comparison of Titanium-nitride-oxide Coated Stents and Sirolimus-eluting Stents for Coronary Revascularization

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Publisher :
ISBN 13 :
Total Pages : 62 pages
Book Rating : 4.:/5 (81 download)

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Book Synopsis Long-term Comparison of Titanium-nitride-oxide Coated Stents and Sirolimus-eluting Stents for Coronary Revascularization by : Annette Barbara Lauterburg

Download or read book Long-term Comparison of Titanium-nitride-oxide Coated Stents and Sirolimus-eluting Stents for Coronary Revascularization written by Annette Barbara Lauterburg and published by . This book was released on 2011 with total page 62 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Impact of Vessel Size on Outcome After Implantation of Sirolimus-eluting and Paclitaxel-eluting Stents

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Publisher :
ISBN 13 :
Total Pages : 9 pages
Book Rating : 4.:/5 (428 download)

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Book Synopsis Impact of Vessel Size on Outcome After Implantation of Sirolimus-eluting and Paclitaxel-eluting Stents by : Stéphanie Ilona Eber

Download or read book Impact of Vessel Size on Outcome After Implantation of Sirolimus-eluting and Paclitaxel-eluting Stents written by Stéphanie Ilona Eber and published by . This book was released on 2007 with total page 9 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Developing Polypyrrole Coated Coronary Stents for Extended Release of Sirolimus

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Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (141 download)

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Book Synopsis Developing Polypyrrole Coated Coronary Stents for Extended Release of Sirolimus by : Niloofar Allahverdi

Download or read book Developing Polypyrrole Coated Coronary Stents for Extended Release of Sirolimus written by Niloofar Allahverdi and published by . This book was released on 2013 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Coronary heart disease remains the biggest killer worldwide. Amongst all the treatment options, drug-eluting stents (DES) are thought to be the most effective method of treatment for the majority of patients. Despite the early success of DES in treating coronary artery disease, concerns and uncertainties were raised. The most critical limitations are poor drug release profiles, hypersenisvity reactions and delayed endothelium healing which can lead to fatal thrombotic events. Therefore there is a need to develop a more effective DES. The aim of this work was to develop a novel DES coating with an improved drug release profile. This project investigated the potential use of conducting polymers for stent coatings in order to improve drug release profiles. Polypyrrole is a biocompatible conducting polymer with distinct chemical/physical properties. Sirolimus is a hydrophobic anti-proliferative drug which retains in the vessel wall to inhibit SMC proliferation. During this investigation polypyrole coated devices were created with the ability to release sirolimus over a therapeutically relevant period of time. Electrochemical electropolymerisation technology was used to produce a series of poylyrrole coatings on stainless steel wires. Different voltages were used during the potentiostatic electropolymerisation process. Then the coated wires were immersed in different concentrations of sirolimus to determine the relationship between electropolymerisation voltage, drug concentrations and the drug release profiles generated. To achieve this, drug-polymer coated wires were immersed in a physiological release medium and samples were taken at various time points up to 28 days, and sirolimus release was analysed using UV spectroscopy. It was found that there is a direct relationship between the concentration of the drug used in the coating solution and the drug release profile. Therefore by varying the concentration of sirolimus, an optimal drug release profile could be achieved. However no direct relationship was found between the electropolymerisation voltage level and the sirolimus release profiles. This is a preliminary study and with further research it may be possible to modify drug release profiles by varying the voltage levels.