Sialic Acids Part I Historical Background And Development And Chemical Synthesis

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Sialic Acids, Part I: Historical Background and Development and Chemical Synthesis

Author :
Publisher : Academic Press
ISBN 13 : 0128155361
Total Pages : 364 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Sialic Acids, Part I: Historical Background and Development and Chemical Synthesis by :

Download or read book Sialic Acids, Part I: Historical Background and Development and Chemical Synthesis written by and published by Academic Press. This book was released on 2018-11-30 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sialic Acids, Volume 75, the latest release in the Advances in Carbohydrate Chemistry and Biochemistry series provides critical and informative articles written by research specialists that integrate the industrial, analytical and technological aspects of biochemistry, organic chemistry and instrumentation methodology to the study of carbohydrates. The series' articles present a definitive interpretation of the current status and future trends in carbohydrate chemistry and biochemistry, with this release covering The Early Exploration of the Sialic Acid World, Sialic Acid Chemistry, Sialic Acids in Evolution and Ontogenesis, Sialic Acids in Neurology, Sialic Acids in Cancer Biology, Sialic Acids in Virology, and more. Features contributions from leading authorities and industry experts who specialize in carbohydrate chemistry, biochemistry and research Integrates the industrial, analytical and technological aspects of biochemistry, organic chemistry and instrumentation methodology in the study of carbohydrates Informs and updates on all the latest developments in the field

Biology of the Sialic Acids

Author : A. Rosenberg
Publisher : Springer Science & Business Media
ISBN 13 : 9780306449741
Total Pages : 398 pages
Book Rating : 4.4/5 (497 download)

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Book Synopsis Biology of the Sialic Acids by : A. Rosenberg

Download or read book Biology of the Sialic Acids written by A. Rosenberg and published by Springer Science & Business Media. This book was released on 1995-07-31 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: Abraham Rosenberg assembles the groundbreaking work of preeminent international scientists to provide the most current, state-of-the-art presentation of research in siabiology. This concise volume examines the historical development of the field and reviews current knowledge on the genetic, immunologic, oncologic, neurodevelopmental, pathogenic, and cell regulatory properties of sialic acid. Outstanding features of this work include exhaustive reference material and detailed information tables.

Sialic Acids, Part II: Biological and Biomedical Aspects

Author : David C. Baker
Publisher : Academic Press
ISBN 13 : 0128171480
Total Pages : 193 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Sialic Acids, Part II: Biological and Biomedical Aspects by : David C. Baker

Download or read book Sialic Acids, Part II: Biological and Biomedical Aspects written by David C. Baker and published by Academic Press. This book was released on 2019-03-07 with total page 193 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sialic Acids, Volume 76, the most recent release in the Advances in Carbohydrate Chemistry and Biochemistry series, is the second volume of a two-volume set devoted to the sialic acids. Vol. 76, devoted to the biological and biomedical aspects of sialic acids, includes chapters on "Sialic Acids in Neurology," "Sialic Acids in Nonenveloped Virus Infections," and "The Biology of Gangliosides," all written by leading experts in their fields. Features contributions from leading authorities and industry experts who specialize in carbohydrate chemistry, biochemistry and research Integrates the industrial, analytical and technological aspects of biochemistry, organic chemistry and instrumentation methodology in the study of carbohydrates Informs and updates on all the latest developments in the field

Marine Glycobiology, Glycomics and Lectins

Author : Yasuhiro Ozeki
Publisher : MDPI
ISBN 13 : 3039218204
Total Pages : 176 pages
Book Rating : 4.0/5 (392 download)

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Book Synopsis Marine Glycobiology, Glycomics and Lectins by : Yasuhiro Ozeki

Download or read book Marine Glycobiology, Glycomics and Lectins written by Yasuhiro Ozeki and published by MDPI. This book was released on 2019-11-20 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt: Glycans (carbohydrate chains) of marine creatures are rich and diverse in polysaccharides, glycoproteins, and glycolipids. The chains that are metabolized by glycan-related enzymes (glycosyltransferases and glycosidases) are recognized by glycan-binding proteins (lectins) which regulate cellular processes such as growth, differentiation, and death. Marine glycomics that involves the genome and transcriptome accelerates our understanding of the evolution of glycans, glycan-related enzymes, and lectins. From 2017 to 2019, the Special Issue “Marine Glycobiology, Glycomics and Lectins” of the journal Marine Drugs published scientific articles and reviews, on the background of “glycobiology”—that is, glycan-based biosciences. The aim was to promote the discovery of novel biomolecules that contribute to drug development and clinical studies. This has great potential for establishing connections between the fields of both human health and marine life sciences. This book contains 11 scientific papers representing current topics in comprehensive glycosciences related to therapeutic agents from marine natural products, as outlined.

Essentials of Glycobiology

Author : Ajit Varki
Publisher : CSHL Press
ISBN 13 : 9780879696818
Total Pages : 694 pages
Book Rating : 4.6/5 (968 download)

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Book Synopsis Essentials of Glycobiology by : Ajit Varki

Download or read book Essentials of Glycobiology written by Ajit Varki and published by CSHL Press. This book was released on 1999 with total page 694 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sugar chains (glycans) are often attached to proteins and lipids and have multiple roles in the organization and function of all organisms. "Essentials of Glycobiology" describes their biogenesis and function and offers a useful gateway to the understanding of glycans.

Biological Roles of Sialic Acid

Author : Abraham Rosenberg
Publisher : Springer
ISBN 13 : 9781468422283
Total Pages : 376 pages
Book Rating : 4.4/5 (222 download)

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Book Synopsis Biological Roles of Sialic Acid by : Abraham Rosenberg

Download or read book Biological Roles of Sialic Acid written by Abraham Rosenberg and published by Springer. This book was released on 2012-04-02 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is a startling amount of research activity concerning the role of sialic acid in mammalian cells and in the mammalian organism. One may discern in the early literature premonitions of compounds containing sialic acid, traceable by descriptions of color reactions, as far back as the turn of the century. Work spanning the 1930s to the 1950s culmi nated in the crystallization of sialic acid from a wide variety of biological materials. The ubiquitous nature of the sialic acids, and the biological importance of the substances in which they occur, then became generally manifest. Since then, the chemistry and metabolism of sialic acid and its occurrence, notably, but not exclusively, in the outer cell surfaces of mammalian cells and in key extracellular glycoproteins, have received great attention. The involvement of sialic acid-containing substances in tumorigenicity and in numerous metabolic and infectious pathological conditions, and in the growth, development, and integrity of mammalian cells has achieved widespread recognition. Intensive inquiry into the biological roles of sialic acid continues in a large number of research laboratories throughout the world. This book is intended to represent for the uninitiated as well as for the expert a wide and detailed overview of the current state of knowledge. Major efforts and pioneering break throughs have emerged from several laboratories, located on both sides of the Atlantic, of which we make no special individual mention here since they will to some extent appear in the pages that follow.

Handbook of Carbohydrate Engineering

Author : Kevin J. Yarema
Publisher : CRC Press
ISBN 13 : 1420027638
Total Pages : 944 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Handbook of Carbohydrate Engineering by : Kevin J. Yarema

Download or read book Handbook of Carbohydrate Engineering written by Kevin J. Yarema and published by CRC Press. This book was released on 2005-05-27 with total page 944 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Handbook of Carbohydrate Engineering provides an overview of the basic science, theory, methods, and applications of this broad, interdisciplinary field. The text provides background information along with practical knowledge for current and future research methodologies used in the characterization and synthesis of various carbohydrates. This

Microbial Glycobiology

Author : Anthony P Moran
Publisher : Elsevier
ISBN 13 : 0080923240
Total Pages : 1037 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Microbial Glycobiology by : Anthony P Moran

Download or read book Microbial Glycobiology written by Anthony P Moran and published by Elsevier. This book was released on 2009-10-01 with total page 1037 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents in an easy-to-read format a summary of the important central aspects of microbial glycobiology, i.e. the study of carbohydrates as related to the biology of microorganisms. Microbial glycobiology represents a multidisciplinary and emerging area with implications for a range of basic and applied research fields, as well as having industrial, medical and biotechnological implications. Individual chapters provided by leading international scientists in the field yield insightful, concise and stimulating reviews Provides researchers with an overview and synthesis of the latest research Each chapter begins with a brief 200 word Summary/Abstract detailing the topic and focus of the chapter, as well as the concepts to be addressed Allows researchers to see at a glance what each chapter will cover Each chapter includes a Research Focus Box Identifies important problems that still need to be solved and areas that require further investigation

Handbook of In Vivo Chemistry in Mice

Author : Katsunori Tanaka
Publisher : John Wiley & Sons
ISBN 13 : 3527344322
Total Pages : 560 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Handbook of In Vivo Chemistry in Mice by : Katsunori Tanaka

Download or read book Handbook of In Vivo Chemistry in Mice written by Katsunori Tanaka and published by John Wiley & Sons. This book was released on 2020-04-27 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides timely, comprehensive coverage of in vivo chemical reactions within live animals This handbook summarizes the interdisciplinary expertise of both chemists and biologists performing in vivo chemical reactions within live animals. By comparing and contrasting currently available chemical and biological techniques, it serves not just as a collection of the pioneering work done in animal-based studies, but also as a technical guide to help readers decide which tools are suitable and best for their experimental needs. The Handbook of In Vivo Chemistry in Mice: From Lab to Living System introduces readers to general information about live animal experiments and detection methods commonly used for these animal models. It focuses on chemistry-based techniques to develop selective in vivo targeting methodologies, as well as strategies for in vivo chemistry and drug release. Topics include: currently available mouse models; biocompatible fluorophores; radionuclides for radiodiagnosis/radiotherapy; live animal imaging techniques such as positron emission tomography (PET) imaging; magnetic resonance imaging (MRI); ultrasound imaging; hybrid imaging; biocompatible chemical reactions; ligand-directed nucleophilic substitution chemistry; biorthogonal prodrug release strategies; and various selective targeting strategies for live animals. -Completely covers current techniques of in vivo chemistry performed in live animals -Describes general information about commonly used live animal experiments and detection methods -Focuses on chemistry-based techniques to develop selective in vivo targeting methodologies, as well as strategies for in vivo chemistry and drug release -Places emphasis on material properties required for the development of appropriate compounds to be used for imaging and therapeutic purposes in preclinical applications Handbook of In Vivo Chemistry in Mice: From Lab to Living System will be of great interest to pharmaceutical chemists, life scientists, and organic chemists. It will also appeal to those working in the pharmaceutical and biotechnology industries.

Dynamics of Bone and Cartilage Metabolism

Author : Markus J. Seibel
Publisher : Elsevier
ISBN 13 : 9780080456263
Total Pages : 920 pages
Book Rating : 4.4/5 (562 download)

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Book Synopsis Dynamics of Bone and Cartilage Metabolism by : Markus J. Seibel

Download or read book Dynamics of Bone and Cartilage Metabolism written by Markus J. Seibel and published by Elsevier. This book was released on 2006-07-24 with total page 920 pages. Available in PDF, EPUB and Kindle. Book excerpt: This updated edition is a comprehensive treatise that spans the complete range of basic biochemistry of bone and cartilage components to the clinical evaluation of disease markers in bone and joint disorders. With contributions from over 75 international experts, Dynamics of Bone and Cartilage Metabolism, Second Edition, is indispensable reading for those involved in skeletal research as well as for rheumatologists, endocrinologists, clinical biochemists, and other clinical disciplines participating in the management of patients with bone and cartilage diseases. Part I provides an up-to-date account of current knowledge of the structure, biosynthesis and molecular biology of the major tissue components Part II covers the organizational structure and cellular metabolism of bone and cartilage Part III deals with the utility of components specific to bone and cartilage as biomarkers of health and disease

Preparative Carbohydrate Chemistry

Author : Stephen Hanessian
Publisher : CRC Press
ISBN 13 : 9780824798024
Total Pages : 668 pages
Book Rating : 4.7/5 (98 download)

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Book Synopsis Preparative Carbohydrate Chemistry by : Stephen Hanessian

Download or read book Preparative Carbohydrate Chemistry written by Stephen Hanessian and published by CRC Press. This book was released on 1997-01-02 with total page 668 pages. Available in PDF, EPUB and Kindle. Book excerpt: Detailing commonly used methods and procedures, this reference discusses the reactions and derivative forms of carbohydrates. Preparative Carbohydrate Chemistry covers the formation, cleavage, and reactions of derivatives and illustrates bond-forming reactions of SN2 types, free radicals, chain extensions, and branching. The contents include: sugar derivatives; selected reactions in carbohydrate chemistry; chemical synthesis of oligosaccharides and O-and N -glycosyl compounds; enzymatic synthesis of sialic acid, KDO, and related deoxyulosonic acids, and of oligosaccharides; synthesis of -glycosyl compounds; carbocycles from carbohydrates; and total synthesis of sugars from non-sugars. This authoritative reference offers relevant chapters on reactions and derivative forms of carbohydrates, including commonly used methods as well as new experimental procedures. It also contains insightful chapter commentaries and succinct topic histories.

Systems and Synthetic Metabolic Engineering

Author : Yanfeng Liu
Publisher : Academic Press
ISBN 13 : 0128217537
Total Pages : 294 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Systems and Synthetic Metabolic Engineering by : Yanfeng Liu

Download or read book Systems and Synthetic Metabolic Engineering written by Yanfeng Liu and published by Academic Press. This book was released on 2020-07-25 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: Systems and Synthetic Metabolic Engineering provides an overview of the development of metabolic engineering within medicine that is fueled by systems and synthetic biology. These newly developed, successful strategies of metabolic engineering guide the audience on how to propose and test proper strategies for metabolic engineering research. In addition to introductory, regulatory and challenges in the field, the book also covers dynamic control and autonomous regulation to control cell metabolism, along with computational modeling and industrial applications. The book is written by leaders in the field, making it ideal for synthetic biologists, researchers, students and anyone working in this area. Discusses the current progress of metabolic engineering, focusing on systems biology and synthetic biology Covers introductory, regulatory, strategies, production and challenges in the field Written technically for synthetic biologists, researchers, students, industrialists, policymakers and stakeholders

Carbohydrate-based Drug Discovery

Author : Chi-Huey Wong
Publisher : John Wiley & Sons
ISBN 13 : 3527605789
Total Pages : 980 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Carbohydrate-based Drug Discovery by : Chi-Huey Wong

Download or read book Carbohydrate-based Drug Discovery written by Chi-Huey Wong and published by John Wiley & Sons. This book was released on 2006-03-06 with total page 980 pages. Available in PDF, EPUB and Kindle. Book excerpt: To exploit the full potential of this diverse compound class for the development of novel active substances, this handbook presents the latest knowledge on carbohydrate chemistry and biochemistry. While it is unique in covering the entire field, particular emphasis is placed on carbohydrates with pharmaceutical potential. Topics include the following: > Chemical Synthesis of Carbohydrates > Carbohydrate Biosynthesis and Metabolism > Carbohydrate Analysis > Cellular Functions of Carbohydrates > Development of Carbohydrate-based Drugs A premier resource for carbohydrate chemists and drug developers, this comprehensive two-volume work contains contributions by more than 50 of the world's leading carbohydrate chemists.

Emery and Rimoin’s Principles and Practice of Medical Genetics and Genomics

Author : Reed E. Pyeritz
Publisher : Academic Press
ISBN 13 : 0128152370
Total Pages : 320 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Emery and Rimoin’s Principles and Practice of Medical Genetics and Genomics by : Reed E. Pyeritz

Download or read book Emery and Rimoin’s Principles and Practice of Medical Genetics and Genomics written by Reed E. Pyeritz and published by Academic Press. This book was released on 2021-11-02 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: Emery and Rimoin’s Principles and Practice of Medical Genetics and Genomics: Perinatal and Reproductive Genetics, Seventh Edition includes the latest information on seminal topics such as prenatal diagnosis, genome and exome sequencing, public health genetics, genetic counseling, and management and treatment strategies in this growing field. The book is ideal for medical students, residents, physicians and researchers involved in the care of patients with genetic conditions. This comprehensive, yet practical resource emphasizes theory and research fundamentals related to applications of medical genetics across the full spectrum of inherited disorders and applications to medicine more broadly. Chapters from leading international researchers and clinicians focus on topics ranging from single gene testing to whole genome sequencing, whole exome sequencing, gene therapy, genome editing approaches, FDA regulations on genomic testing and therapeutics, and ethical aspects of employing genomic technologies. Fully revised and up-to-date, this new edition introduces genetic researchers, students and healthcare professionals to genomic technologies, testing and therapeutic applications Examines key topics and developing methods within genomic testing and therapeutics, including single gene testing, whole genome and whole exome sequencing, gene therapy and genome editing, variant Interpretation and classification, and ethical aspects of applying genomic technologies Includes color images that support the identification, concept illustration, and method of processing Features contributions by leading international researchers and practitioners of medical genetics Provides a robust companion website that offers further teaching tools and links to outside resources and articles to stay up-to-date on the latest developments in the field

Glycosylation and Cancer

Author :
Publisher : Academic Press
ISBN 13 : 0128016140
Total Pages : 418 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Glycosylation and Cancer by :

Download or read book Glycosylation and Cancer written by and published by Academic Press. This book was released on 2015-02-26 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. Here, once again, outstanding and original reviews are presented on a variety of topics. Provides information on cancer research Outstanding and original reviews Suitable for researchers and students

Progress in Molecular Biology and Translational Science

Author :
Publisher : Academic Press
ISBN 13 : 012817739X
Total Pages : 418 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Progress in Molecular Biology and Translational Science by :

Download or read book Progress in Molecular Biology and Translational Science written by and published by Academic Press. This book was released on 2019-03-22 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: Glycans and Glycosaminoglycans as Clinical Biomarkers and Therapeutics - Part A, Volume 162 in the Progress in Molecular Biology and Translational Science series provides informative monographs on a variety of research topics related to Glycans and glycosaminoglycans as clinical biomarkers and therapeutics. Topics in this update include Glycan-based Biomarkers for Diagnosis of Cancers and Other Diseases: Past, Present and Future, Desialylation in Diseases and its Application in Diagnostic and Therapeutic Development, Proteoglycans as Miscommunication Biomarkers for Cancer Diagnosis, Fucosylation in Cancer Biology and Its Clinical Applications, Retrospective Analysis of Glycan-Related Biomarkers Based on Clinical Laboratory Data in Two Medical Centers, and many related topics. Includes comprehensive coverage of molecular biology Presents ample use of tables, diagrams, schemata and color figures to enhance the reader's ability to rapidly grasp the information provided Contains contributions from renowned experts in the field

Carbohydrates: The Essential Molecules of Life

Author : Robert V. Stick
Publisher : Elsevier
ISBN 13 : 9780080927022
Total Pages : 496 pages
Book Rating : 4.9/5 (27 download)

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Book Synopsis Carbohydrates: The Essential Molecules of Life by : Robert V. Stick

Download or read book Carbohydrates: The Essential Molecules of Life written by Robert V. Stick and published by Elsevier. This book was released on 2010-08-06 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the "nuts and bolts" background for a successful study of carbohydrates - the essential molecules that not only give you energy, but are an integral part of many biological processes. A question often asked is 'Why do carbohydrate chemistry?' The answer is simple: It is fundamental to a study of biology. Carbohydrates are the building blocks of life and enable biological processes to take place. Therefore the book will provide a taste for the subject of glycobiology. Covering the basics of carbohydrates and then the chemistry and reactions of carbohydrates this book will enable a chemist to gain essential knowledge that will enable them to move smoothly into the worlds of biochemistry, molecular biology and cell biology. * includes perspective from new co-author Spencer Williams, who enhances coverage of the connection between carbohydrates and life * describes the basic chemistry and biology of carbohydrates * reviews the concepts, synthesis, reactions, and biology of carbohydrates