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Author : Laura Lynne Helmuth
Publisher :
ISBN 13 :
Total Pages : 188 pages
Book Rating : 4.:/5 (33 download)
Download or read book Sequence Learning in Patients with Parkinson's Disease written by Laura Lynne Helmuth and published by . This book was released on 1997 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Katherine R. Gamble
Publisher :
ISBN 13 :
Total Pages : 294 pages
Book Rating : 4.:/5 (889 download)
Download or read book Implicit Sequence Learning in People with Parkinson's Disease written by Katherine R. Gamble and published by . This book was released on 2014 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: People with Parkinson's disease (PD) have known deficits in striatal dopamine, and compared to age-matched healthy older adults, increased striatal deficits, and difficulties with maintaining postural stability and complex language comprehension, behaviors that involve sequencing. Because sequencing abilities are important for daily life and for various types of rehabilitation, this decline with PD should be well understood, yet the literature on the effects of PD in sequence learning is mixed. Some of the confusion in the literature may be due to variation in participant characteristics, but also to task differences, such as the extent of motor movement required. The present studies examined implicit sequence learning using the Triplets Learning Task (TLT) in a PD group. There were 29 medicated PD participants, and 30 healthy older adults were recruited as a control group. Study 1 compared learning over several blocks of training in the TLT. Two learning measures indicated that people with PD learned, but they showed less implicit sequence learning than Controls. This group difference in one analysis was carried largely by late training, when learning is thought to be particularly dependent on the striatum. Additionally, when first and second halves of blocks were examined separately, the PD group showed less learning than Controls in the second halves of blocks, when learning is thought to be striatal-dependent. In Study 2, we examined relationships between learning and PD-related characteristics. Using learning in the second half block, we found that in our PD group, learning positively correlated with Age, Disease duration and Levodopa levels. These three variables were positively correlated with one another, and therefore it was difficult to disentangle their individual effects. Together, these studies suggest that people with PD were able to learn implicit sequences, though to a lesser degree than Controls, and Levodopa medication may have helped moderate this sequencing deficit. Findings of group differences in learning in sections of training suggest that particular points in training may be more sensitive to sequencing or striatal deficits. Thus, the TLT and these learning analyses could be used to better characterize clinical populations that may have hippocampal or striatal deficits.
Author : 陳雪婷
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (128 download)
Download or read book Effect of a Single Bout of Aerobic Exercise on Implicit Sequence Learning in People with Parkinson's Disease written by 陳雪婷 and published by . This book was released on 2020 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Jason A. Whitfield
Publisher :
ISBN 13 :
Total Pages : 204 pages
Book Rating : 4.:/5 (96 download)
Download or read book SPEECH MOTOR SEQUENCE LEARNING IN PARKINSON DISEASE AND NORMAL AGING written by Jason A. Whitfield and published by . This book was released on 2014 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt: Motor learning relies on the integrity of sensorimotor circuits in the brain, which are largely affected in individuals with Parkinson disease (PD). Additionally, data suggest normal aging can affect various stages of motor learning. Though data are available on the nature of non-speech motor learning, fewer studies have examined how adults with and without motor speech disorders learn speech articulatory sequences. The aim of the current investigation is to examine speech motor sequence learning in normal aging and PD. A speech motor sequence learning task was developed and implemented to examine acquisition, consolidation, and automatization over two days. On Day 1, participants learned a sequence of six monosyllabic nonwords to examine acquisition. This speech motor sequence was re-tested on Day 2 in single- and dual-task conditions to evaluate consolidation and automatization, respectively. Learning was inferred from gains in speed and accuracy of the speech motor sequence. There were no observed effects of aging or PD on speech motor sequence acquisition, as all groups exhibited comparable gains in speed and accuracy on Day 1. However, aging and PD were observed to affect speech motor consolidation following night-time sleep. Specifically, at the Day 2 re-test, young adults exhibited offline gains in speed and accuracy, older adults maintained speed and accuracy (without offline gains), and individuals with PD exhibited offline losses in speed. Only younger adults demonstrated automatization, exhibiting negligible dual-task effects when concurrently performing the speech motor sequence with a visuo-motor task. Conversely, both older adults and individuals with PD exhibited significantly poorer performance of the speech motor sequence in the dual-task condition, with individuals with PD experiencing the largest degree of bidirectional dual-task interference. Overall, the current findings suggest that speech motor learning is affected by both Parkinson Disease and normal aging. Data from the current investigation are largely in line with findings in the non-speech motor sequence learning literature, suggesting that speech and non-speech motor learning may rely on similar neural circuits. As the individuals with PD exhibited deficits in the consolidation and automatization phases of learning, these data may hold important implications for the speech rehabilitation in PD.
Author :
Publisher : Academic Press
ISBN 13 : 0128052910
Total Pages : 2517 pages
Book Rating : 4.1/5 (28 download)
Download or read book Learning and Memory: A Comprehensive Reference written by and published by Academic Press. This book was released on 2017-07-07 with total page 2517 pages. Available in PDF, EPUB and Kindle. Book excerpt: Learning and Memory: A Comprehensive Reference, Second Edition, Four Volume Set is the authoritative resource for scientists and students interested in all facets of learning and memory. This updated edition includes chapters that reflect the state-of-the-art of research in this area. Coverage of sleep and memory has been significantly expanded, while neuromodulators in memory processing, neurogenesis and epigenetics are also covered in greater detail. New chapters have been included to reflect the massive increase in research into working memory and the educational relevance of memory research. No other reference work covers so wide a territory and in so much depth. Provides the most comprehensive and authoritative resource available on the study of learning and memory and its mechanisms Incorporates the expertise of over 150 outstanding investigators in the field, providing a ‘one-stop’ resource of reputable information from world-leading scholars with easy cross-referencing of related articles to promote understanding and further research Includes further reading for each chapter that helps readers continue their research Includes a glossary of key terms that is helpful for users who are unfamiliar with neuroscience terminology
Author :
Publisher : Oxford University Press
ISBN 13 : 0197501591
Total Pages : 401 pages
Book Rating : 4.1/5 (975 download)
Download or read book The Cognitive Unconscious written by and published by Oxford University Press. This book was released on 2022-07-08 with total page 401 pages. Available in PDF, EPUB and Kindle. Book excerpt: The term 'Implicit Learning' refers to the way in which knowledge of fairly complex, patterned material can be acquired without any conscious effort to learn it and with little to no awareness of what has been learned. Over the past fifty years, Implict Learning has became a vigorously researched area in the social sciences. In The Cognitive Unconscious, Arthur S. Reber and Rhianon Allen bring together several dozen experts from social science and neuroscience to present a broad overview of the exploration of the cognitive unconscious. Each chapter delves deeper into a subject that has become an interdisciplinary domain of research to which contributions have been made by sociologists, neuroscientists, evolutionary biologists, linguists, social and organizational psychologists, and sport psychologists, amongst many others. The book shows that unconscious, implicit cognitive processes play a role in virtually everything interesting that human beings do. As the contributors demonstrate, the implicit and explicit elements of cognition form a rich and complex interactive framework that make up who we are. With contributions from over thirty distinguished authors from nine different countries, The Cognitive Unconscious gives a balanced and thorough overview of where the field is today, over a half-century since the first experiments were run.
Author : Siraj Ahmed
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (129 download)
Download or read book Prediction of Rate of Disease Progression in Parkinson's Disease Patients Based on RNA-Sequence Using Deep Learning written by Siraj Ahmed and published by . This book was released on 2020 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The advent of recent high throughput sequencing technologies resulted in an unexplored big data of genomics and transcriptomics that might help to answer various research questions in Parkinson's disease(PD) progression. While the literature has revealed various predictive models that use longitudinal clinical data for disease progression, there is no predictive model based on RNA-Sequence data of PD patients. This study investigates how to predict the PD Progression for a patient's next medical visit by capturing longitudinal temporal patterns in the RNA-Seq data. Data provided by Parkinson Progression Marker Initiative (PPMI) includes 423 PD patients with a variable number of visits for a period of 4 years. We propose a predictive model based on a Recurrent Neural Network (RNN) with dense connections. The results show that the proposed architecture is able to predict PD progression from high dimensional RNA-seq data with a Root Mean Square Error (RMSE) of 6.0 and rank-order correlation of (r=0.83, p
Author : Jay Alberts
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (588 download)
Download or read book Deep Brain Stimulation and Sequence Motor Learning in Parkinson's Disease written by Jay Alberts and published by . This book was released on 2003 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Leon Kenemans
Publisher : Bloomsbury Publishing
ISBN 13 : 1137296143
Total Pages : 331 pages
Book Rating : 4.1/5 (372 download)
Download or read book Psychology in the Brain written by Leon Kenemans and published by Bloomsbury Publishing. This book was released on 2017-09-16 with total page 331 pages. Available in PDF, EPUB and Kindle. Book excerpt: Taking an integrated approach to cognitive neuroscience, this is essential reading for advanced undergraduate and postgraduate students and researchers. Offering original insight through its unique structure, it explains why we need to understand the brain in order to understand psychology.
Author : Marsha S. Corrigan
Publisher : Nova Publishers
ISBN 13 : 9781600217166
Total Pages : 268 pages
Book Rating : 4.2/5 (171 download)
Download or read book Pattern Recognition in Biology written by Marsha S. Corrigan and published by Nova Publishers. This book was released on 2007 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pattern recognition is the research area that studies the operation and design of systems that recognise patterns in data. It encloses subdisciplines like discriminant analysis, feature extraction, error estimation, cluster analysis (together sometimes called statistical pattern recognition), grammatical inference and parsing (sometimes called syntactical pattern recognition). Important application areas are image analysis, character recognition, speech analysis, man and machine diagnostics, person identification and industrial inspection. This book presents leading-edge research from around the world.
Author : Henning Plessner
Publisher : Psychology Press
ISBN 13 : 1136875220
Total Pages : 356 pages
Book Rating : 4.1/5 (368 download)
Download or read book Intuition in Judgment and Decision Making written by Henning Plessner and published by Psychology Press. This book was released on 2011-05-20 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: The central goal of this volume is to bring the learning perspective into the discussion of intuition in judgment and decision making. The book gathers recent work on intuitive decision making that goes beyond the current dominant heuristic processing perspective. However, that does not mean that the book will strictly oppose this perspective. The unique perspective of this book will help to tie together these different conceptualizations of intuition and develop an integrative approach to the psychological understanding of intuition in judgment and decision making. Accordingly, some of the chapters reflect prior research from the heuristic processing perspective in the new light of the learning perspective. This book provides a representative overview of what we currently know about intuition in judgment and decision making. The authors provide latest theoretical developments, integrative frameworks and state-of-the-art reviews of research in the laboratory and in the field. Moreover, some chapters deal with applied topics. Intuition in Judgment and Decision Making aims not only at the interest of students and researchers of psychology, but also at scholars from neighboring social and behavioral sciences such as economy, sociology, political sciences, and neurosciences.
Author : Mazda Beigi
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (16 download)
Download or read book Incidental Motor Sequence Learning written by Mazda Beigi and published by . This book was released on 2013 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: To survive in a complex changing environment humans frequently need to adapt their behaviour incidentally from normal interactions in the environment without any specific intention to learn. Whilst there is a considerable body of research into incidental learning of sequential information there is still fundamental debate regarding its cognitive basis, the associated neural mechanisms and the way in which it is affected by neurological disease. These issues were explored, in normal participants and neurological patients, using manipulations of the Serial Reaction Task [SRT] in which participants gradually learn a stimulus sequence (usually screen locations) after responding to each item by pressing corresponding response buttons. The first two experiments (chapter 3) demonstrate that the specific metric used to quantify learning and the occurrence of highly salient repeat locations may inflate estimates of learning in tasks with increased motor demands. The next three experiments (chapter 4) examine whether a secondary (not directly behaviourally relevant) information source during the SRT facilitates chunking in memory and overall learning. In a spatial SRT task (specified by horizontal location), additional spatial information (vertical location) enhanced learning but a secondary perceptual property (colour) produced a cost. However, in a perceptual SRT a secondary perceptual property (colour) had no effect. The next study demonstrates that impairments of incidental learning in Parkinson's disease are partially reduced by administration of l-Dopa. Implications for models of striatal function and studies suggesting implicit learning is impaired by l-Dopa are discussed. Finally, the impact of Deep Brain Stimulation of the GPi is investigated in a population known to have only limited cognitive deficits relating to their illness (dystonia). Despite previous reports of impaired intentional learning in participants with a high genetic risk of Dystonia, there was no evidence for any impairment before or after stimulation. Implications across studies and future research directions are also discussed.
Author : Marie T. Banich
Publisher : Cambridge University Press
ISBN 13 : 1316507904
Total Pages : 675 pages
Book Rating : 4.3/5 (165 download)
Download or read book Cognitive Neuroscience written by Marie T. Banich and published by Cambridge University Press. This book was released on 2018-04-05 with total page 675 pages. Available in PDF, EPUB and Kindle. Book excerpt: Updated thoroughly, this comprehensive text highlights the most important issues in cognitive neuroscience, supported by clinical applications.
Author : Emily Keshner
Publisher : Frontiers Media SA
ISBN 13 : 2889632954
Total Pages : 215 pages
Book Rating : 4.8/5 (896 download)
Download or read book Current State of Postural Research - Beyond Automatic Behavior written by Emily Keshner and published by Frontiers Media SA. This book was released on 2020-01-16 with total page 215 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Larry R. Squire
Publisher : Guilford Press
ISBN 13 : 9781572308985
Total Pages : 544 pages
Book Rating : 4.3/5 (89 download)
Download or read book Neuropsychology of Memory, Third Edition written by Larry R. Squire and published by Guilford Press. This book was released on 2003-03-13 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: This important reference and text brings together leading neuroscientists to describe approaches to the study of memory. Among major approaches covered are lesions; electrophysiology; single-unit recording; pharmacology; and molecular genetics. Chapters are organized into three sections, presenting state-of-the-art studies of memory in humans, nonhuman primates, and rodents and birds. Each chapter explicates the theoretical and methodological underpinnings of the authors' research program, reviews the latest empirical findings, and identifies salient directions for future investigation. Included are more than 50 illustrations.
Author :
Publisher : ScholarlyEditions
ISBN 13 : 1464993882
Total Pages : 407 pages
Book Rating : 4.4/5 (649 download)
Download or read book Neurodegenerative Diseases—Advances in Research and Treatment: 2012 Edition written by and published by ScholarlyEditions. This book was released on 2012-12-26 with total page 407 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurodegenerative Diseases—Advances in Research and Treatment: 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Neurodegenerative Diseases. The editors have built Neurodegenerative Diseases—Advances in Research and Treatment: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Neurodegenerative Diseases in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Neurodegenerative Diseases—Advances in Research and Treatment: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Author : Jean-Claude Dreher
Publisher : Academic Press
ISBN 13 : 0080923488
Total Pages : 527 pages
Book Rating : 4.0/5 (89 download)
Download or read book Handbook of Reward and Decision Making written by Jean-Claude Dreher and published by Academic Press. This book was released on 2009-06-04 with total page 527 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses a fundamental question about the nature of behavior: how does the brain process reward and makes decisions when facing multiple options? The book presents the most recent and compelling lesion, neuroimaging, electrophysiological and computational studies, in combination with hormonal and genetic studies, which have led to a clearer understanding of neural mechanisms behind reward and decision making. The neural bases of reward and decision making processes are of great interest to scientists because of the fundamental role of reward in a number of behavioral processes (such as motivation, learning and cognition) and because of their theoretical and clinical implications for understanding dysfunctions of the dopaminergic system in several neurological and psychiatric disorders (schizophrenia, Parkinson's disease, drug addiction, pathological gambling, ...) Comprehensive coverage of approaches to studying reward and decision making, including primate neurophysiology and brain imaging studies in healthy humans and in various disorders, genetic and hormonal influences on the reward system and computational models. Covers clinical implications of process dysfunction (e.g., schizophrenia, Parkinson's disease, eating disorders, drug addiction, pathological gambling) Uses multiple levels of analysis, from molecular mechanisms to neural systems dynamics and computational models. " This is a very interesting and authoritative handbook by some of the most outstanding investigators in the field of reward and decision making ", Professor Edmund T. Rolls, Oxford Center for Computational Neuroscience, UK
