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Sackler Colloquium On Self Perpetuating Structural States In Biology Disease And Genetics
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Book Synopsis Sackler Colloquium on Self-Perpetuating Structural States in Biology, Disease, and Genetics by :
Download or read book Sackler Colloquium on Self-Perpetuating Structural States in Biology, Disease, and Genetics written by and published by . This book was released on 2002 with total page 3 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :Proceedings of the National Academy of Sciences Publisher :National Academies Press ISBN 13 :0309084458 Total Pages :442 pages Book Rating :4.3/5 (9 download)
Book Synopsis Self-Perpetuating Structural States in Biology, Disease, and Genetics by : Proceedings of the National Academy of Sciences
Download or read book Self-Perpetuating Structural States in Biology, Disease, and Genetics written by Proceedings of the National Academy of Sciences and published by National Academies Press. This book was released on 2002 with total page 442 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past half-century, the central dogma, in which DNA makes RNA makes protein, has dominated thinking in biology, with continuing refinements in understanding of DNA inheritance, gene expression, and macromolecular interactions. However, we have also witnessed the elucidation of epigenetic phenomena that violate conventional notions of inheritance. Protein-only inheritance involves the transmission of phenotypes by self-perpetuating changes in protein conformation. Proteins that constitute chromatin can also transmit heritable information, for example, via posttranslational modifications of histones. Both the transmission of phenotypes via the formation of protein conformations and the inheritance of chromatin states involve self-perpetuating assemblies of proteins, and there is evidence for some common structural features and conceptual frameworks between them. To foster interactions between researchers in these two fields, the National Academy of Sciences convened an Arthur M.Sackler Colloquium entitled "Self-Perpetuating Structural States in Biology, Disease, and Genetics" in Washington, DC, on March 22-24, 2002. Participants described new phenomenology and provided insights into fundamental mechanisms of protein and chromatin inheritance. Perhaps most surprising to attendees was emerging evidence that these unconventional modes of inheritance may be common.
Book Synopsis Proceedings of the National Academy of Sciences of the United States of America by : National Academy of Sciences (U.S.)
Download or read book Proceedings of the National Academy of Sciences of the United States of America written by National Academy of Sciences (U.S.) and published by . This book was released on 2002 with total page 1456 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Strengthening Forensic Science in the United States by : National Research Council
Download or read book Strengthening Forensic Science in the United States written by National Research Council and published by National Academies Press. This book was released on 2009-07-29 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scores of talented and dedicated people serve the forensic science community, performing vitally important work. However, they are often constrained by lack of adequate resources, sound policies, and national support. It is clear that change and advancements, both systematic and scientific, are needed in a number of forensic science disciplines to ensure the reliability of work, establish enforceable standards, and promote best practices with consistent application. Strengthening Forensic Science in the United States: A Path Forward provides a detailed plan for addressing these needs and suggests the creation of a new government entity, the National Institute of Forensic Science, to establish and enforce standards within the forensic science community. The benefits of improving and regulating the forensic science disciplines are clear: assisting law enforcement officials, enhancing homeland security, and reducing the risk of wrongful conviction and exoneration. Strengthening Forensic Science in the United States gives a full account of what is needed to advance the forensic science disciplines, including upgrading of systems and organizational structures, better training, widespread adoption of uniform and enforceable best practices, and mandatory certification and accreditation programs. While this book provides an essential call-to-action for congress and policy makers, it also serves as a vital tool for law enforcement agencies, criminal prosecutors and attorneys, and forensic science educators.
Book Synopsis Paranoia: A Study in Diagnosis by : A. Fried
Download or read book Paranoia: A Study in Diagnosis written by A. Fried and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 243 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is a curious parallel between the philosophy of science and psychiatric theory. The so-called demarcation question, which has exercised philosophers of science over the last decades, posed the problem of distinguishing science proper from non-science - in par ticular, from metaphysics, from pseudo-science, from the non rational or irrational, or from the untestable or the empirically meaningless. In psychiatric theory, the demarcation question appears as a problem of distinguishing the sane from the insane, the well from the mentally ill. The parallelism is interesting when the criteria for what fails to be scientific are seen to be congruent with the criteria which define those psychoses which are marked by cognitive failure. In this book Dr Yehuda Fried and Professor Joseph Agassi - a practicing psychiatrist and a philosopher of science, respectivel- focus on an extreme case of psychosis - paranoia - as an essentially intellectual disorder: that is, as one in which there is a systematic and chronic delusion which is sustained by logical means. They write: "Paranoia is an extreme case by the very fact that paranoia is by definition a quirk of the intellectual apparatus, a logical delusion. " (p. 2.
Download or read book Rheumaderm written by Carmel Mallia and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 539 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book represents the proceedings of a conference, Rheumaderm, that was held in December 1997. The meeting was a dialogue between the specialties of Rheumatology and Dermatology, exploring and discussing areas of common interest. The aim was to present problems common to both specialties, thereby emphasising the team approach to such problems and helping to combine various skills.
Book Synopsis Index of Conference Proceedings by : British Library. Document Supply Centre
Download or read book Index of Conference Proceedings written by British Library. Document Supply Centre and published by . This book was released on 2003 with total page 870 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis In the Light of Evolution by : National Academy of Sciences
Download or read book In the Light of Evolution written by National Academy of Sciences and published by National Academies Press. This book was released on 2017-01-01 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biodiversity-the genetic variety of life-is an exuberant product of the evolutionary past, a vast human-supportive resource (aesthetic, intellectual, and material) of the present, and a rich legacy to cherish and preserve for the future. Two urgent challenges, and opportunities, for 21st-century science are to gain deeper insights into the evolutionary processes that foster biotic diversity, and to translate that understanding into workable solutions for the regional and global crises that biodiversity currently faces. A grasp of evolutionary principles and processes is important in other societal arenas as well, such as education, medicine, sociology, and other applied fields including agriculture, pharmacology, and biotechnology. The ramifications of evolutionary thought also extend into learned realms traditionally reserved for philosophy and religion. The central goal of the In the Light of Evolution (ILE) series is to promote the evolutionary sciences through state-of-the-art colloquia-in the series of Arthur M. Sackler colloquia sponsored by the National Academy of Sciences-and their published proceedings. Each installment explores evolutionary perspectives on a particular biological topic that is scientifically intriguing but also has special relevance to contemporary societal issues or challenges. This tenth and final edition of the In the Light of Evolution series focuses on recent developments in phylogeographic research and their relevance to past accomplishments and future research directions.
Book Synopsis Religion and Power by : Nicole Maria Brisch
Download or read book Religion and Power written by Nicole Maria Brisch and published by Institute for the Study of Ancient Cultures. This book was released on 2008 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume represents a collection of contributions presented during the Third Annual University of Chicago Oriental Institute Seminar Religion and Power: Divine Kingship in the Ancient World and Beyond, held at the Oriental Institute, February 23-24, 2007. The purpose of this conference was to examine more closely concepts of kingship in various regions of the world and in different time periods. The study of kingship goes back to the roots of fields such as anthropology and religious studies, as well as Assyriology and Near Eastern archaeology. More recently, several conferences have been held on kingship, drawing on cross-cultural comparisons. Yet the question of the divinity of the king as god has never before been examined within the framework of a cross-cultural and multi-disciplinary conference. Some of the recent anthropological literature on kingship relegates this question of kings who deified themselves to the background or voices serious misgivings about the usefulness of the distinction between divine and sacred kings. Several contributors to this volume have pointed out the Western, Judeo-Christian background of our categories of the human and the divine. However, rather than abandoning the term divine kingship because of its loaded history it is more productive to examine the concept of divine kingship more closely from a new perspective in order to modify our understanding of this term and the phenomena associated with it.
Book Synopsis Chromosome Structural Analysis by : Wendy Bickmore
Download or read book Chromosome Structural Analysis written by Wendy Bickmore and published by OUP Oxford. This book was released on 1999-05-20 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt: The DNA of eukaryotes is packaged into chromosomes - each chromosome consisting of a very long molecule of DNA and various proteins (e.g. histones), and the number of chromosomes being characteristic for the species concerned. Chromosome analysis can provide a great deal of information for many aspects of cellular genetics such as DNA replication, protein:DNA interactions and genetic manipulation. The book is structured in a methodical fashion - the introductory chapters are centred around analysis of chromatin with chapters on the mapping of protein:DNA interactions in vivo using ligation-mediated PCR and the mapping of chromatin-associated proteins by formaldehyde cross-linking. The next chapters concentrate on the study of whole chromosome structure, including: fission yeast chromosome analysis using FISH and CHIP, isolation of vertebrate metaphase chromosomes and their analysis by FISH, the study of vertebrate chromosome progression through mitosis, and the analysis of mammalian interphase chromosomes by immunofluorescence and FISH. There then follow chapters on FISH in whole-mount tissues and the analysis of the sub-structure of mammalian nuclei in vitro. The final two chapters deal with the experimental manipulation of chromosome structure, including: chromosome assembly in vitro using Xenopus egg extracts and chromosome fragmentation in vertebrate cell lines. This comprehensive and informative laboratory manual includes a diverse range of experimental models for the analysis of chromosomes - such as vertebrates, Drosophila, yeast and Xenopus. Fully illustrated, it focuses on modern techniques and approaches to the study of chromosome structure and will be invaluable to researchers and academic staff in genetics, biomedical science and molecular biology.
Book Synopsis Ancient Egyptian Coffins by : John H. Taylor
Download or read book Ancient Egyptian Coffins written by John H. Taylor and published by . This book was released on 2018 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains the proceedings of the twenty-third Annual Egyptological Colloquium, held at the British Museum in 2014, augmented by additional papers. The twenty-three contributions investigate functionality, iconography and manufacture of ancient Egyptian coffins from the First Intermediate Period to the eighth century AD. The authors explore the conceptual aspects which lay behind the production of coffins through the study of iconography and texts, examining the functional role of these complex objects as 'structured compositions' which were designed to play an important part in transforming the deceased occupants and perpetuating their existence beyond death. Reinstating coffins in their archaeological and societal contexts, the papers reflect on the circumstances in which they were made, considering workshop practices and regional variability, and studying coffins not only individually but also as components of larger conceptual entities in which the mummy, the burial chamber and the tomb itself all had specific meanings. Several contributions focus on areas of current interest, such as the post-burial adaptation and reuse of coffins, considering how these issues relate to the economic environment in which they were made and to changing attitudes towards the immutability of burial arrangements.
Book Synopsis A Companion to Archaeology by : John Bintliff
Download or read book A Companion to Archaeology written by John Bintliff and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Companion to Archaeology features essays from 27 of the world’s leading authorities on different types of archaeology that aim to define the field and describe what it means to be an archaeologist. Shows that contemporary archaeology is an astonishingly broad activity, with many contrasting specializations and ways of approaching the material record of past societies. Includes essays by experts in reading the past through art, linguistics, or the built environment, and by professionals who present the past through heritage management and museums. Introduces the reader to a range of archaeologists: those who devote themselves to the philosophy of archaeology, those who see archaeology as politics or anthropology, and those who contend that the essence of the discipline is a hard science.
Book Synopsis Emergency Dermatology by : Ronni Wolf
Download or read book Emergency Dermatology written by Ronni Wolf and published by CRC Press. This book was released on 2017-02-24 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: There are many emergencies that the dermatologist needs to address and many cutaneous diseases in the emergency room that require rapid dermatologic consultation. The dermatologist is frequently the first physician to examine such patients before a hospital admission and also the first to identify a critical situation, stabilize the patient, and choose urgent and appropriate intervention. Both the practicing dermatologist and the emergency physician will benefit from the revised and updated edition of this text from top international dermatologists, enabling them to hone their diagnostic skills, expand their knowledge and understanding of pathologic events, and learn treatment options available for acute life-threatening skin diseases in this complicated and multifaceted field.
Book Synopsis Microbial Genetics by : Stanley R. Maloy
Download or read book Microbial Genetics written by Stanley R. Maloy and published by Jones & Bartlett Publishers. This book was released on 1994 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The revision of this classic textbook by David Freifelder has been rewritten and updated to include the numerous and recent advances in microbial genetics. The basic format, organization and style of the first edition has been retained.
Book Synopsis Medical genetics 1 by : John Kaisermann
Download or read book Medical genetics 1 written by John Kaisermann and published by Cambridge Stanford Books. This book was released on with total page 199 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medical genetics encompasses many different areas, including the clinical practice of doctors, genetic counselors and nutritionists, clinical diagnostic laboratory activities and research on the causes and inheritance of genetic disorders. Examples of conditions that are within the scope of medical genetics include birth defects and dysmorphology, mental retardation, autism, mitochondrial disorders, skeletal dysplasia, connective tissue disorders, cancer genetics, teratogens and prenatal diagnosis. Medical genetics is becoming increasingly relevant for many common diseases. Overlaps with other medical specialties are beginning to emerge, as recent advances in genetics are revealing etiologies for neurological, endocrine, cardiovascular, pulmonary, ophthalmological, renal, psychiatric and dermatological diseases. Summary of the contents of this book: Genetic disorders: Classification Chromosomal disorders Mitochondrial diseases: Mitochondrial genetics Proteopathy The human genome and the chromosomal base of inheritance Cancer cytogenetics The human genome and its chromosomes DNA structure: a brief summary Organization of human chromosomes Cell division The human karyotype Human gametogenesis and fertilization Importance and medical significance of Mitosis and Meiosis Structure and function of the human genome Genome Keys
Book Synopsis The Capitalist and the Activist by : Tom C. W. Lin
Download or read book The Capitalist and the Activist written by Tom C. W. Lin and published by Berrett-Koehler Publishers. This book was released on 2022-01-11 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt: 2023 Axiom Business Books Award Silver Medalist (Business Commentary) 2023 Nautilus Book Award Silver Medalist (Social Change & Social Justice) This is the first in-depth examination of the important ongoing fusion of activism, capitalism, and social change masterfully told through a compelling narrative filled with vivid stories and striking studies. Corporations and their executives are at the forefront of some of the most contentious and important social issues of our time. Through pronouncements, policies, boycotts, sponsorships, lobbying, and fundraising, corporations are actively engaged in issues like immigration reform, gun regulation, racial justice, gender equality, and religious freedom. Despite corporate social activism being everywhere these days-witness how quickly companies and progressives united to oppose North Carolina's bathroom bill or support the Black Lives Matter movement-there has been no in-depth examination of the far-reaching consequences of this movement. What first principles should guide businesses' approaches? How should activists engage with businesses in a way that is most beneficial to their causes? What are potential pitfalls and risks associated with corporate social activism for activists, businesses, and society at large? Weaving studies and stories, Temple University professor of law, Tom C. W. Lin offers a road map for how we got here and a compass for where we are going as a nation of capitalists and activists seeking profit and progress.
Book Synopsis The Oxford Handbook of the Science of Science Communication by : Kathleen Hall Jamieson
Download or read book The Oxford Handbook of the Science of Science Communication written by Kathleen Hall Jamieson and published by Oxford University Press. This book was released on 2017 with total page 513 pages. Available in PDF, EPUB and Kindle. Book excerpt: On topics from genetic engineering and mad cow disease to vaccination and climate change, this Handbook draws on the insights of 57 leading science of science communication scholars who explore what social scientists know about how citizens come to understand and act on what is known by science.