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Role Of Immune System In Kidney Cancer
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Book Synopsis Role of Immune System in Kidney Cancer by : Ana Marisa Chudzinski-Tavassi
Download or read book Role of Immune System in Kidney Cancer written by Ana Marisa Chudzinski-Tavassi and published by . This book was released on 2019 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Almost all kidney cancers are associated to immune dysfunction. Among these, renal cell carcinoma (RCC) represents approximately 2% of malignancies that affect adults and for 90,Äì95% of all kidney cancers. Recent evidences have collaborated to elucidate the mechanisms involved in the development of this disease. In this view, dysfunctional neutrophil migration, as well as T lymphocyte-DC (dendritic cell) cross talk, DC maturation, immune cell metabolism, and reactivity and abnormal expression of cytokines and chemokines and their receptors have been highlighted in RCC and stroma cells. A rational development of novel therapies to recover antitumor activity of immune system is closely related to the understanding of the complex interactions between immune system and tumor. Some insights have been reached and immunomodulatory molecules, such as interleukin-2 (IL-2) and IFN-Œ±, immune checkpoint inhibitors, and chemokines antagonists have shown clinical efficacy. In this chapter, we overview the essential role of innate and adaptive immune response in RCC and discuss drugs approved or in development for its treatment.
Book Synopsis Evolving Trends in Kidney Cancer by : Sashi S. Kommu
Download or read book Evolving Trends in Kidney Cancer written by Sashi S. Kommu and published by BoD – Books on Demand. This book was released on 2020-07-22 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: Kidney cancer imposes a significant cancer burden and its incidence continues to rise globally. Mortality in advanced kidney cancer remains high despite oncological, surgical and multimodal optimisation. Genetic associations, heterogeneity and limitations in early diagnosis through lack of optimal biomarkers add to the challenges. Over the last two decades there has been an exponential increase in diagnostic and therapeutic advances in the management of kidney cancer. The coupling of scientific advances in engineering and technology with oncological therapeutics has recently ushered a renewed optimism. The role of minimally invasive approaches through focal therapy and surgical extirpation using the robotic platform has been unprecedented and paramount. Virtual augmentation and mixed reality platforms have proved useful supplementary tools in surgical planning. The role of surgical simulation and training in development of surgeons with the optimal skill set is essential to provide optimal care. This book is the first in a series that explores the evolving trends in kidney cancer. The focus of the book is broad and includes topics ranging from immunotherapy to surgical simulation. Some chapters explore leading edge concepts while others capture the evolving trends and future concepts. The Editors aim to stimulate the readers to explore the key concepts and to encourage research and innovation along the main themes presented.
Book Synopsis Nephron-Sparing Surgery by : Krishna Sasidharan
Download or read book Nephron-Sparing Surgery written by Krishna Sasidharan and published by CRC Press. This book was released on 2007-10-18 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite the rising popularity of the minimally invasive laparoscopic option, open nephron-sparing surgery is still seen by many experts as the 'gold standard' for open surgery for kidney tumors and should remain the first choice for many patients. This challenges the idea that less-invasive therapies are always more desirable than open surgery. Whi
Book Synopsis 100 Questions & Answers About Kidney Cancer by : Steven C. Campbell
Download or read book 100 Questions & Answers About Kidney Cancer written by Steven C. Campbell and published by Jones & Bartlett Learning. This book was released on 2015-02-25 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: Whether you’re a newly diagnosed patient or a friend or relative of someone suffering from kidney cancer, this book can help. Offering both doctor and patient perspectives, 100 Questions & Answers About Kidney Cancer, Second Edition provides authoritative and practical answers to the most commonly asked questions by patients and their loved ones. What is kidney cancer? What causes kidney cancer? How is kidney cancer treated? Along with the answers to these and other questions, this book provides information on the different types of kidney cancer, signs and symptoms, treatment options, and more. Written by experts in the field 100 Questions & Answers About Kidney Cancer, Second Edition is an invaluable resource for anyone coping with the physical and emotional uncertainty of this disease.
Book Synopsis 100 Questions & Answers About Kidney Cancer by : Steven C. Campbell
Download or read book 100 Questions & Answers About Kidney Cancer written by Steven C. Campbell and published by Jones & Bartlett Learning. This book was released on 2018-09-11 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: Offering both doctor and patient perspectives, 100 Questions & Answers About Kidney Cancer, Third Edition provides authoritative and practical answers to the most commonly asked questions by patients and their loved ones.
Download or read book Kidney Cancer written by Primo N. Lara and published by Springer. This book was released on 2015-06-10 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Kidney Cancer: Principles and Practice is a comprehensive and interdisciplinary textbook that encompasses all clinically relevant aspects of the disease. This new edition has been extensively updated and includes brand new material covering the most recent developments in kidney cancer diagnosis and therapy. The user-friendly and clinically oriented content of the book guarantees that it will be of great interest to a wide range of medical professionals, and every effort has been made to ensure that contributions are both easy to understand and directly related to patient care. Content presentation departs from the usual dense chapter format featuring a lengthy series of paragraphs. Instead, each chapter contains several boxed sections, including one that summarizes essential "take home points" for the busy clinician and another that presents a patient-oriented case highlighting the clinical application of elements discussed in that chapter. In addition, accessible original images, illustrations, and diagrams (some in full color) are used to simplify particularly complex material. This book will be of value for clinicians, researchers, residents, fellows, students, and knowledgeable lay people. The contributors comprise an international group of authors with expertise in kidney cancer epidemiology, molecular biology, pathology, diagnosis, clinical features, staging, prognostic and predictive factors, surgery, systemic therapy, and emerging investigational approaches, among others.
Book Synopsis Onco-Nephrology E-Book by : Kevin W. Finkel
Download or read book Onco-Nephrology E-Book written by Kevin W. Finkel and published by Elsevier Health Sciences. This book was released on 2019-07-02 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt: Kidney disease and cancer are frequent comorbidities that require specialized knowledge and expertise from both the nephrologist and the oncologist. Written by three pioneers in this growing subspecialty, Onco-Nephrology provides authoritative, definitive coverage of the mechanism and management of these two life-threatening diseases. This unique, single-volume resource covers current protocols and recommends management therapies to arrest kidney failure and allow oncologic treatments to continue and succeed. Addresses acute and chronic kidney diseases that develop from a variety of cancers. This includes direct kidney injury from the malignancy, paraneoplastic effects of the cancer, and various cancer agents used to treat the malignancy. Discusses key issues regarding kidney disease in patients with cancer, including conventional chemotherapeutic regimens and new novel therapies (targeted agents and immunotherapies) or the malignancies themselves that may promote kidney injury; patients with chronic kidney disease who acquire cancer unrelated to renal failure; and kidney transplantation, which has been shown to carry an increased risk of cancer. Contains dedicated chapters for each class of the conventional chemotherapeutic agents, targeted cancer agents, and cancer immunotherapies including the basic science, pathogenic mechanisms of injury, clinical manifestations, and treatment. Includes special chapters devoted to the individual classes of chemotherapies that relate to kidney disease for quick reference. Discusses increasingly complex problems due to more numerous and specialized anti-cancer drugs, as well as increased survival rates for both cancer and renal failure requiring long-term patient care. Covers anti-VEGF (antivascular endothelial growth factor) agents and cancer immunotherapies – treatments that are being recognized for adverse kidney effects. Utilizes a clear, logical format based on the ASN Core Curriculum for Onco-Nephrology, making this reference an excellent tool for board review, as well as a practical resource in daily practice.
Book Synopsis Anatomy and Physiology by : J. Gordon Betts
Download or read book Anatomy and Physiology written by J. Gordon Betts and published by . This book was released on 2013-04-25 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Kidney Cancer by : Linda Bickerstaff
Download or read book Kidney Cancer written by Linda Bickerstaff and published by The Rosen Publishing Group, Inc. This book was released on 2011-01-15 with total page 66 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduces kidney cancer, discusses the causes, diagnosing, and treatment of it, and examines recent advances in treating it.
Book Synopsis Chemotherapy and Immunotherapy in Urologic Oncology by : Edouard J. Trabulsi
Download or read book Chemotherapy and Immunotherapy in Urologic Oncology written by Edouard J. Trabulsi and published by Springer Nature. This book was released on 2020-09-29 with total page 303 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is designed to familiarize clinical practitioners in systemic therapy options and medical management of urologic malignancies including prostate cancer, bladder and upper tract urothelial carcinoma, and renal cell carcinoma. Organized by organ system, the text highlights new therapies such as novel forms of androgen deprivation, cytotoxic chemotherapy, immune check point and immunomodulatory agents, and targeted therapies. Written by experts in the field, the book also reviews current chemotherapy and immunotherapy regimens for genitourinary malignancies and discusses indications, outcomes, and toxicities, as well as clinical trial concepts. Each of the book’s chapters offers a bulleted box of clinical pearls on the particular role of the APP. Chemotherapy and Immunotherapy in Urologic Oncology: A Guide for the Advanced Practice Provider is a resource for urologists, uro-radiologists, medical clinicians and family practitioners alike, familiarizing its audiences with systemic therapy regimens for urologic malignancies, as well as their expected outcomes and side effects.
Download or read book Kidney Cancer written by Ethan D. and published by Shuttle Systems. This book was released on 2024-03-11 with total page 229 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Kidney Cancer: A Comprehensive Resource for Patients and Families" is an essential guide for anyone affected by kidney cancer. This book provides a thorough understanding of the disease, from its basic anatomy and function to the latest treatments and research advancements, making it an invaluable resource for patients and their loved ones. In-Depth Understanding of Kidney CancerBegin your journey to understanding kidney cancer with an overview of the disease, its types, and risk factors. Gain insight into the anatomy and function of the kidneys and how cancer affects these vital organs. Recognizing Signs and SymptomsLearn about the early warning signs and symptoms of kidney cancer. This knowledge is crucial for early detection, which can significantly impact treatment success. Navigating the Diagnostic ProcessExplore the diagnostic tests and imaging techniques used to diagnose kidney cancer. Understand biopsy procedures and what your diagnosis means, helping demystify the initial stages of facing the disease. Staging and Grading ExplainedGrasp the intricacies of staging and grading kidney cancer. This information is vital for understanding the prognosis and planning the most effective treatment strategies. Comprehensive Treatment OptionsDelve into the various treatment options available, including surgery, radiation therapy, chemotherapy, and innovative targeted therapies. Stay informed about emerging treatments and how clinical trials might offer additional options. Coping with DiagnosisFind guidance on coping with the emotional and psychological impact of a kidney cancer diagnosis. Learn about available support systems, counseling options, and effective strategies for managing stress and anxiety. Nutritional and Lifestyle ManagementDiscover the importance of nutritional management and lifestyle changes in supporting kidney health. Get practical advice on diet, exercise, and adjusting your lifestyle post-diagnosis. Chronic Management and Quality of LifeUnderstand the challenges of living with kidney cancer, including managing chronic symptoms, improving quality of life, and navigating survivorship and long-term care. Dealing with Treatment Side EffectsLearn how to manage the common side effects and complications of treatment, as well as the long-term impact on your health. Special Considerations for Diverse PopulationsGain insights into how kidney cancer affects different populations, including children, the elderly, and considerations for gender differences in treatment and care. Finding Support and Building CommunityDiscover resources for community support, advocacy for kidney cancer awareness, and how to connect with others who are facing similar challenges. Looking to the FutureStay updated on ongoing research efforts and innovations in kidney cancer care. This book offers hope and a look toward future advancements in treatment. "Kidney Cancer: A Comprehensive Resource for Patients and Families" is more than just a book; it's a partner in your journey through kidney cancer. It provides the knowledge, support, and resources needed to navigate this challenging path with confidence and hope.
Book Synopsis Immunological Surveillance by : Macfarlane Burnet
Download or read book Immunological Surveillance written by Macfarlane Burnet and published by Elsevier. This book was released on 2014-05-17 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immunological Surveillance
Book Synopsis The Basics of Cancer Immunotherapy by : Haidong Dong
Download or read book The Basics of Cancer Immunotherapy written by Haidong Dong and published by Springer. This book was released on 2018-01-05 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides patients and their physicians (especially “non-oncologist” health care providers) with a clear and concise introduction to cancer immunotherapy, which, unlike traditional forms of cancer therapy, acts by boosting the patient’s own immune system to fight cancer. The unique features of cancer immunotherapy make its management, monitoring and side-effects different from those of traditional cancer therapy. Especially novel are the side effects of cancer immunotherapy, necessitating greater awareness for both patients and physicians in order to minimize complications of therapy. The patient-friendly, concise, easy-to-understand, and up-to-date knowledge presented in this book will inform patients about the benefits and risks of cancer immunotherapy, and help them and their care providers to understand how immunotherapy would control their unique disease. Researchers and academic professionals in the field of cancer immunotherapy will also find clear and useful information to help them communicate with patients or address unresolved problems. Some key features of the book are: Expertise. All editors and authors are scientists and oncologists specializing in cancer immunotherapy, and are involved in scientific discovery from the early stage of immune-checkpoint inhibitors to today’s daily patient care. Their insights, expertise and experience guarantee the high quality and authority in the science, medicine and practice of cancer immunotherapy. Patient-friendly. This book is written for cancer patients in order to meet their needs when considering immunotherapy. As an educational tool, this book will help the reader balance the risks and benefits based on both science and clinical facts, and therefore to make the best choice in receiving or withdrawing from immunotherapy. Disease Specificity. Cancer is a complicated disease involving multiple stages and pathology. Its response to immunotherapy is individualized and varies depending on cancer types. The authors’ expertise in treating different types of cancers, including melanoma, lung, kidney, bladder, and lymphoma, provides disease-specific insights in applying immunotherapy to each disease.
Book Synopsis Renal Cell Carcinoma by : José I. López
Download or read book Renal Cell Carcinoma written by José I. López and published by MDPI. This book was released on 2020-04-22 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: Renal cancer is a health problem of major concern worldwide. Although tyrosine kinase inhibitors and immune check-point blockade treatments, alone or in combination, are giving promising results, failures are quite frequent due to intratumor heterogeneity and to the acquisition of drug resistance. The spectrum of renal cell carcinoma subtypes is wide. Up to 70–80% of renal tumors are clear cell renal cell carcinomas, a clinically aggressive tumor subtype linked to VHL gene inactivation. Next in frequency, the papillary renal cell carcinoma category encompasses an intricate puzzle of classic and newly described entities with poorly defined limits, some of them pending definite clarification. Likewise, the chromophobe–oncocytoma duality, the so-called hybrid tumors and oncocytic neoplasms, remain to be well profiled. Finally, a growing list of very uncommon renal tumors linked to specific molecular signatures fulfill the current portrait of renal cell neoplasia. This Special Issue of Cancers regards RCC from very different perspectives, from the intimate basic mechanisms governing this disease to the clinical practice principles of their diagnoses and treatments. The interested reader will have the opportunity to contact with some of the most recent findings and will be updated with excellent reviews.
Book Synopsis Upper Tract Urothelial Carcinoma by : Shahrokh F. Shariat
Download or read book Upper Tract Urothelial Carcinoma written by Shahrokh F. Shariat and published by Springer. This book was released on 2014-09-13 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: Upper Tract Urothelial Carcinoma represents the first book of its kind to be dedicated solely to UTUC. It's aim is to improve understanding and eventually care of a disease that is greatly understudied and underappreciated, yet commonly dealt with by many medical and urologic oncologists. The volume features new data regarding genetic susceptibility, gene expression studies and causative factors; contemporary concepts and controversies regarding diagnosis and staging of UTUC; prediction tools and their value in treatment decisions within each disease stage and patient selection and treatment options such as endoscopic management, distal ureterectomy, radical nephroureterectomy and chemotherapy. Up-to-date information regarding boundaries of surgical resection, indication and extent of lymphadenectomy is covered as well as the role of perioperative/neoadjuvant chemotherapy in patients with high-risk UTUC. Upper Tract Urothelial Carcinoma will be of great value to all Urologists, Medical Oncologists and fellows in Urologic Oncology as well as upper level residents in training in Urology and Medical Oncology.
Book Synopsis Chemokines and Cancer by : Barrett Rollins
Download or read book Chemokines and Cancer written by Barrett Rollins and published by Springer Science & Business Media. This book was released on 1999 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the introduction of microscopy, pathologists have noted tumor infiltration by inflammatory cells and presumed that this represents the host's attempt to reject its tumor. Recent advances in the molecular biology of inflammation have revealed the signals involved in attracting inflammatory cells to tumors and, for the most part, these signals are mediated by chemokines and their receptors. Chemokines are low molecular weight proteins that attract and activate specific subsets of leukocytes to the exclusion of others.
Book Synopsis Immunotherapy of Renal Cell Carcinoma by : Frans M.J. Debruyne
Download or read book Immunotherapy of Renal Cell Carcinoma written by Frans M.J. Debruyne and published by Springer. This book was released on 1991-01-29 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: With contributions by numerous experts
