Role Of Capsaicin In Oxidative Stress And Cancer

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Role of Capsaicin in Oxidative Stress and Cancer

Author : Sanjay K. Srivastava
Publisher : Springer Science & Business Media
ISBN 13 : 9400763174
Total Pages : 183 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Role of Capsaicin in Oxidative Stress and Cancer by : Sanjay K. Srivastava

Download or read book Role of Capsaicin in Oxidative Stress and Cancer written by Sanjay K. Srivastava and published by Springer Science & Business Media. This book was released on 2013-04-23 with total page 183 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the mechanism of the anti-cancer effects of capsaicin including the involvement of cytochrome P-450 in the bioactivation; identification of mitochondria as the key target site for oxidative stress; involvement of mitochondrial respiratory chain in the production of ROS; prevention of chemically-induced carcinogenesis, discussion on TRPV-1 receptor mediated or independent anti-cancer effects; identification of p53 activation as a possible mechanism; involvement of Cox-2 in apoptosis, suppression of transcription factors such as NF-kB and STAT-3; inhibition of cell survival pathways including PI3K/Akt and the involvement of intrinsic mitochondrial cell death pathway.

Handbook of Oxidative Stress in Cancer: Therapeutic Aspects

Author : Sajal Chakraborti
Publisher : Springer Nature
ISBN 13 : 9811654220
Total Pages : 4078 pages
Book Rating : 4.8/5 (116 download)

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Book Synopsis Handbook of Oxidative Stress in Cancer: Therapeutic Aspects by : Sajal Chakraborti

Download or read book Handbook of Oxidative Stress in Cancer: Therapeutic Aspects written by Sajal Chakraborti and published by Springer Nature. This book was released on 2022-09-28 with total page 4078 pages. Available in PDF, EPUB and Kindle. Book excerpt: This reference book, which is the second volume of Targeting Oxidative Stress in Cancer, explores oxidative stress as the potential therapeutic target for cancer therapy. The initial chapters discuss the molecular mechanisms of oxidative stress and its effects on different signaling pathways. Subsequently, the sections examine the impact of redox signaling on tumor cell proliferation and consider the therapeutic potential of dietary phytochemicals and nutraceuticals in reactive oxygen species (ROS)-induced cancer. In turn, it examines the evidence supporting the use of Vitamin C in cancer management, before presenting various synthetic and natural compounds that have therapeutic implications for oxidative stress-induced cancer. It also explores the correlation between non-coding RNA and oxidative stress. Furthermore, the book summarizes the role of stem cells in ROS-induced cancer therapy and reviews the therapeutic applications of nanoparticles to alter redox haemostasis in cancer cells. Lastly, it explores heat-shock proteins, ubiquitin ligases, and probiotics as potential therapeutic agents in ROS-mediated cancer. This book is a useful resource for basic and translational scientists as well as clinicians interested in the field of oxidative stress and cancer therapy.

Inflammation, Oxidative Stress, and Cancer

Author : Ah-Ng Tony Kong
Publisher : CRC Press
ISBN 13 : 1466503718
Total Pages : 631 pages
Book Rating : 4.4/5 (665 download)

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Book Synopsis Inflammation, Oxidative Stress, and Cancer by : Ah-Ng Tony Kong

Download or read book Inflammation, Oxidative Stress, and Cancer written by Ah-Ng Tony Kong and published by CRC Press. This book was released on 2016-04-19 with total page 631 pages. Available in PDF, EPUB and Kindle. Book excerpt: Increasing scientific evidence suggests that the majority of diseases including cancer are driven by oxidative stress and inflammation, attributed to environmental factors. These factors either drive genetic mutations or epigenetically modify expression of key regulatory genes. These changes can occur as early as gestational fetal development, and

Oxidative Stress, Disease And Cancer

Author : Keshav K Singh
Publisher : World Scientific
ISBN 13 : 1783260114
Total Pages : 1105 pages
Book Rating : 4.7/5 (832 download)

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Book Synopsis Oxidative Stress, Disease And Cancer by : Keshav K Singh

Download or read book Oxidative Stress, Disease And Cancer written by Keshav K Singh and published by World Scientific. This book was released on 2006-04-04 with total page 1105 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book aims to provide a comprehensive review of the most up-to-date knowledge of the sources and molecular mechanisms of oxidative stress, and its role in disease and cancer. It also focuses on the novel agents and methods that can be employed to prevent oxidative stress and associated diseases.The authors first review the most recent data on the basic mechanisms of oxidative stress. The second section discusses oxidative stress leading to several diseases and cancers, and in the third section, the strategies employed in the prevention and treatment of oxidative stress-related diseases are discussed.

Bioactive Molecules in Food

Author : Jean-Michel Mérillon
Publisher : Springer Nature
ISBN 13 : 3319780301
Total Pages : 2353 pages
Book Rating : 4.3/5 (197 download)

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Book Synopsis Bioactive Molecules in Food by : Jean-Michel Mérillon

Download or read book Bioactive Molecules in Food written by Jean-Michel Mérillon and published by Springer Nature. This book was released on 2019-01-25 with total page 2353 pages. Available in PDF, EPUB and Kindle. Book excerpt: This reference work provides comprehensive information about the bioactive molecules presented in our daily food and their effect on the physical and mental state of our body. Although the concept of functional food is new, the consumption of selected food to attain a specific effect existed already in ancient civilizations, namely of China and India. Consumers are now more attentive to food quality, safety and health benefits, and the food industry is led to develop processed- and packaged-food, particularly in terms of calories, quality, nutritional value and bioactive molecules. This book covers the entire range of bioactive molecules presented in daily food, such as carbohydrates, proteins, lipids, isoflavonoids, carotenoids, vitamin C, polyphenols, bioactive molecules presented in wine, beer and cider. Concepts like French paradox, Mediterranean diet, healthy diet of eating fruits and vegetables, vegan and vegetarian diet, functional foods are described with suitable case studies. Readers will also discover a very timely compilation of methods for bioactive molecules analysis. Written by highly renowned scientists of the field, this reference work appeals to a wide readership, from graduate students, scholars, researchers in the field of botany, agriculture, pharmacy, biotechnology and food industry to those involved in manufacturing, processing and marketing of value-added food products.

Cancer

Author : Victor R Preedy
Publisher : Academic Press
ISBN 13 : 0128195630
Total Pages : 592 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Cancer by : Victor R Preedy

Download or read book Cancer written by Victor R Preedy and published by Academic Press. This book was released on 2021-01-14 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer: Oxidative Stress and Dietary Antioxidants, Second Edition, covers the science of oxidative stress in cancer and the potentially therapeutic usage of natural antioxidants in the diet or food matrix. The processes within the science of oxidative stress are described in concert with other processes, such as apoptosis, cell signaling, and receptor-mediated responses. This approach recognizes that diseases are often multifactorial and that oxidative stress is a single component. Other sections cover new organ site tumors—skin and liver cancer, the role of polymorphisms, cytochrome p450s, COX gene, fatty acids, apoptosis, T cells and mitochondria, prevention/protection with anthocyanins, esculetin, nanoparticles, and more. This book is a valuable resource for cancer researchers, oncologists, nutritionists and other members of the biomedical field who are interested in enhancing treatment outcome, improving the quality of life of patients, and developing new treatments in the fight against cancer. Encompasses updated, revised and state-of-the-art information to advance cancer research Bridges the gaps between nutrition, oxidative stress, and cancer, presenting a holistic approach for health care and research Contains wide applicability to cancer research, from prevention to novel therapeutics

Oxidative Stress and Redox Regulation

Author : Ursula Jakob
Publisher : Springer Science & Business Media
ISBN 13 : 9400757875
Total Pages : 488 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Oxidative Stress and Redox Regulation by : Ursula Jakob

Download or read book Oxidative Stress and Redox Regulation written by Ursula Jakob and published by Springer Science & Business Media. This book was released on 2013-03-15 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many physiological conditions such as host defense or aging and pathological conditions such as neurodegenerative diseases, and diabetes are associated with the accumulation of high levels of reactive oxygen species and reactive nitrogen species. This generates a condition called oxidative stress. Low levels of reactive oxygen species, however, which are continuously produced during aerobic metabolism, function as important signaling molecules, setting the metabolic pace of cells and regulating processes ranging from gene expression to apoptosis. For this book we would like to recruit the experts in the field of redox chemistry, bioinformatics and proteomics, redox signaling and oxidative stress biology to discuss how organisms achieve the appropriate redox balance, the mechanisms that lead to oxidative stress conditions and the physiological consequences that contribute to aging and disease.

Oxidative Stress in Cancer, AIDS, and Neurodegenerative Diseases

Author : Luc Montagnier
Publisher : CRC Press
ISBN 13 : 1482292211
Total Pages : 575 pages
Book Rating : 4.4/5 (822 download)

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Book Synopsis Oxidative Stress in Cancer, AIDS, and Neurodegenerative Diseases by : Luc Montagnier

Download or read book Oxidative Stress in Cancer, AIDS, and Neurodegenerative Diseases written by Luc Montagnier and published by CRC Press. This book was released on 1997-10-06 with total page 575 pages. Available in PDF, EPUB and Kindle. Book excerpt: Based on a conference on Oxidative Stress and Redox Regulation, held at the Pasteur Institute, Paris, this work examines fundamental, chemical, biological and medical studies of free radicals on different targets and the consequences of their reactivity. It covers the chemistry and biochemistry of free radicals, free radicals as second messengers t

Capsaicin as a Therapeutic Molecule

Author : Omar M. E. Abdel-Salam
Publisher : Springer Science & Business Media
ISBN 13 : 3034808283
Total Pages : 325 pages
Book Rating : 4.0/5 (348 download)

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Book Synopsis Capsaicin as a Therapeutic Molecule by : Omar M. E. Abdel-Salam

Download or read book Capsaicin as a Therapeutic Molecule written by Omar M. E. Abdel-Salam and published by Springer Science & Business Media. This book was released on 2014-03-20 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides an up-to-date account of the achievements pertaining to the application of capsaicin and capsaicin-like molecules in the therapy of various human ailments such as pain, non-allergic rhinitis, obesity, tumors and gastrointestinal, dermatologic and urologic disorders. It discusses the basic functions of the capsaicin receptor (TRPV1), its mechanisms of action and its role in physiological and pathological processes. The text focuses on the most recent progress in the use of capsaicin and capsaicin-like molecules as a therapeutic agent and highlights potential pharmaceutical implications of further TRPV1 research. The chapters are written by noted experts in their fields of endeavor. This book offers both clinicians and researchers valuable resource and reference material on the subject that will stimulate future research.

Paradox Role of Oxidative Stress in Cancer

Author : Cinzia Domenicotti
Publisher : Mdpi AG
ISBN 13 : 9783036544212
Total Pages : 0 pages
Book Rating : 4.5/5 (442 download)

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Book Synopsis Paradox Role of Oxidative Stress in Cancer by : Cinzia Domenicotti

Download or read book Paradox Role of Oxidative Stress in Cancer written by Cinzia Domenicotti and published by Mdpi AG. This book was released on 2022-06-17 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reactive oxygen species (ROS) are produced by healthy cells and are maintained at physiological levels by antioxidant systems. However, when ROS increase in number, a condition of oxidative stress occurs, leading to many human diseases, including cancer. The relationship between oxidative stress and cancer is complex since ROS play a double-edged role in cancer development and under therapy response. This paradox represents a great challenge for researchers and needs to be investigated. The articles collected in this Special Issue can help to clarify the role of ROS modulation in cancer prevention and treatment, and to dissect the molecular mechanisms underlying its paradoxical role in order to counteract carcinogenesis or enhance sensitivity to anticancer therapy.

Capsaicinoids

Author : Mallappa Kumara Swamy
Publisher : Springer Nature
ISBN 13 : 9819977797
Total Pages : 574 pages
Book Rating : 4.8/5 (199 download)

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Book Synopsis Capsaicinoids by : Mallappa Kumara Swamy

Download or read book Capsaicinoids written by Mallappa Kumara Swamy and published by Springer Nature. This book was released on with total page 574 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Paradox Role of Oxidative Stress in Cancer

Author : Cinzia Domenicotti
Publisher :
ISBN 13 : 9783036544229
Total Pages : 0 pages
Book Rating : 4.5/5 (442 download)

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Book Synopsis Paradox Role of Oxidative Stress in Cancer by : Cinzia Domenicotti

Download or read book Paradox Role of Oxidative Stress in Cancer written by Cinzia Domenicotti and published by . This book was released on 2022 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reactive oxygen species (ROS) are produced by healthy cells and are maintained at physiological levels by antioxidant systems. However, when ROS increase in number, a condition of oxidative stress occurs, leading to many human diseases, including cancer. The relationship between oxidative stress and cancer is complex since ROS play a double-edged role in cancer development and under therapy response. This paradox represents a great challenge for researchers and needs to be investigated. The articles collected in this Special Issue can help to clarify the role of ROS modulation in cancer prevention and treatment, and to dissect the molecular mechanisms underlying its paradoxical role in order to counteract carcinogenesis or enhance sensitivity to anticancer therapy.

Food Factors for Cancer Prevention

Author : Hajime Ohigashi
Publisher : Springer Science & Business Media
ISBN 13 : 4431670173
Total Pages : 661 pages
Book Rating : 4.4/5 (316 download)

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Book Synopsis Food Factors for Cancer Prevention by : Hajime Ohigashi

Download or read book Food Factors for Cancer Prevention written by Hajime Ohigashi and published by Springer Science & Business Media. This book was released on 2013-11-27 with total page 661 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chemoprevention is currently regarded as one of the most promising avenues for the control of cancer, with human epidemiological and animal studies indicating that the risk of cancer may be modified by changes in diet. Over 100 papers are collected in this volume, the proceedings of the International Conference on Food Factors: Chemistry and Cancer Prevention, held in Hamamatsu, Japan, in December 1995. Special emphasis is placed on chemical, biological, and molecular properties of phytochemicals in teas, fruit, vegetables, herbs, and spices, and on their potential for cancer prevention. Also discussed are the cancer-preventive effects of vitamins, lipids, carotenoids, flavonoids, and other components of diet. The findings presented here will be invaluable to all who are interested in diet and cancer prevention, and especially to biochemists, pharmacologists, food scientists, and nutritionists.

Current Therapy in Pain

Author : Howard S. Smith
Publisher : Elsevier Health Sciences
ISBN 13 : 1416048367
Total Pages : 697 pages
Book Rating : 4.4/5 (16 download)

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Book Synopsis Current Therapy in Pain by : Howard S. Smith

Download or read book Current Therapy in Pain written by Howard S. Smith and published by Elsevier Health Sciences. This book was released on 2009-01-01 with total page 697 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique resource focuses on the diagnosis and treatment of painful conditions-both acute and chronic-from a multi-disciplinary perspective. Joined by a team of nearly 200 international contributors representing a wide range of specialties, Dr. Smith presents the best management options within and across specialties. Succinct treatment and therapy guidelines enable you to quickly access clinically useful information, for both inpatient and outpatient pain management, while a 2-color format enhances readability and ease of use and highlights key concepts. And, as an Expert Consult title, it includes access to the complete contents online, fully searchable, plus links to Medline and PubMed abstracts-providing rapid, easy consultation from any computer! Includes access to the complete text online, fully searchable, plus links to Medline and PubMed abstracts-providing quick and convenient reference from anyplace with an Internet connection. Offers a cross-discipline approach to pain management for a comprehensive view of the best treatment options within and across specialties including internal medicine, gynecology, physical medicine and rehabilitation, orthopedics, and family medicine. Provides succinct treatment and therapy guidelines, enabling you to locate useful information quickly. Organizes guidance on acute and chronic therapies in a templated format, to facilitate consistent, quick-access consultation appropriate for inpatient or outpatient pain management. Features a 2-color format that enhances readability and ease of use and highlights key concepts. Your purchase entitles you to access the web site until the next edition is published, or until the current edition is no longer offered for sale by Elsevier, whichever occurs first. If the next edition is published less than one year after your purchase, you will be entitled to online access for one year from your date of purchase. Elsevier reserves the right to offer a suitable replacement product (such as a downloadable or CD-ROM-based electronic version) should access to the web site be discontinued.

The Role of Oxidative Stress in Apoptosis of Breast Cancer Cells

Author : Margaret Briehl
Publisher :
ISBN 13 :
Total Pages : 21 pages
Book Rating : 4.:/5 (453 download)

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Book Synopsis The Role of Oxidative Stress in Apoptosis of Breast Cancer Cells by : Margaret Briehl

Download or read book The Role of Oxidative Stress in Apoptosis of Breast Cancer Cells written by Margaret Briehl and published by . This book was released on 1997 with total page 21 pages. Available in PDF, EPUB and Kindle. Book excerpt: In response to specific stimuli, normal cells undergo a process of cell suicide called apoptosis. This project is testing the hypothesis that oxidative stress plays a critical role in the mechanism of apoptosis induced by treatment of human breast cancer cells with tumor necrosis factor-alpha (TNF). TNF treatment of MCF-7 cells was found to increase the expression and activity of manganese superoxide dismutase.

Chemical Biology of Natural Products

Author : David J. Newman
Publisher : CRC Press
ISBN 13 : 1351643282
Total Pages : 650 pages
Book Rating : 4.3/5 (516 download)

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Book Synopsis Chemical Biology of Natural Products by : David J. Newman

Download or read book Chemical Biology of Natural Products written by David J. Newman and published by CRC Press. This book was released on 2017-09-22 with total page 650 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chemical Biology of Natural Products This unique, long-awaited volume is designed to address contemporary aspects of natural product chemistry and its influence on biological systems, not solely on human interactions. The subjects covered include discovery, isolation and characterization, biosynthesis, biosynthetic engineering, pharmaceutical, and other applications of these compounds. Each chapter begins with a brief and simple introduction to the subject matter, and then proceeds to guide the reader towards the more contemporary, cutting-edge research in the field, with the contributing authors presenting current examples from their own work in order to exemplify key themes. Topics covered in the text include genome mining, heterologous expression, natural product synthesis, biosynthesis, glycosylation, chemical ecology, and therapeutic applications of natural products, both current and potential.

Plant-derived Bioactives

Author : Mallappa Kumara Swamy
Publisher : Springer Nature
ISBN 13 : 9811523614
Total Pages : 592 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis Plant-derived Bioactives by : Mallappa Kumara Swamy

Download or read book Plant-derived Bioactives written by Mallappa Kumara Swamy and published by Springer Nature. This book was released on 2020-06-27 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plants produce a vast number of bioactive compounds with different chemical scaffolds, which modulate a diverse range of molecular targets and are used as drugs for treating numerous diseases. Most present-day medicines are derived either from plant compounds or their derivatives, and plant compounds continue to offer limitless reserves for the discovery of new medicines. While different classes of plant compounds, like phenolics, flavonoids, saponins and alkaloids, and their potential pharmacological applications are currently being explored, their curative mechanisms are yet to be understood in detail. This book is divided into 2 volumes and offers detailed information on plant-derived bioactive compounds, including recent research findings. Volume 1, “Plant-derived Bioactives: Chemistry and Mode of Action” discusses the chemistry of highly valued plant bioactive compounds and their mode of actions at the molecular level. Volume 2, “Plant-derived Bioactives: Production, Properties and Therapeutic Applications” explores the sources, biosynthesis, production, biological properties and therapeutic applications of plant bioactives. Given their scope, these books are valuable resources for members of the scientific community wishing to further explore various medicinal plants and the therapeutic applications of their bioactive compounds. They appeal to scholars, teachers and scientists involved in plant product research, and facilitate the development of new drugs.