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Rna Trafficking And Nuclear Structure Dynamics
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Book Synopsis RNA Trafficking and Nuclear Structure Dynamics by : Philippe Jeanteur
Download or read book RNA Trafficking and Nuclear Structure Dynamics written by Philippe Jeanteur and published by Springer. This book was released on 2007-11-03 with total page 153 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume explores nuclear structure and trafficking involving or relevant to RNA and RNPs. Topics include advances and current problems in the structural organization of different subnuclear compartments, Cajal bodies and gems, speckles containing splicing factors, and PML bodies characteristic of ProMyelocytic leukemia. The book also describes the dynamic aspects of RNA trafficking and the latest technologies for live cell imaging of mRNA.
Book Synopsis Single Particle Tracking and Single Molecule Energy Transfer by : Christoph Bräuchle
Download or read book Single Particle Tracking and Single Molecule Energy Transfer written by Christoph Bräuchle and published by John Wiley & Sons. This book was released on 2009-10-30 with total page 359 pages. Available in PDF, EPUB and Kindle. Book excerpt: Closing a gap in the literature, this handbook gathers all the information on single particle tracking and single molecule energy transfer. It covers all aspects of this hot and modern topic, from detecting virus entry to membrane diffusion, and from protein folding using spFRET to coupled dye systems, as well recent achievements in the field. Throughout, the first-class editors and top international authors present content of the highest quality, making this a must-have for physical chemists, spectroscopists, molecular physicists and biochemists.
Book Synopsis Single-stranded RNA phages by : Paul Pumpens
Download or read book Single-stranded RNA phages written by Paul Pumpens and published by CRC Press. This book was released on 2020-02-03 with total page 1832 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a comprehensive guide to single-stranded RNA phages (family Leviviridae), first discovered in 1961. These phages played a unique role in early studies of molecular biology, the genetic code, translation, replication, suppression of mutations. Special attention is devoted to modern applications of the RNA phages and their products in nanotechnology, vaccinology, gene discovery, evolutionary and environmental studies. Included is an overview of the generation of novel vaccines, gene therapy vectors, drug delivery, and diagnostic tools exploring the role of RNA phage-derived products in the revolutionary progress of the protein tethering and bioimaging protocols. Key Features Presents the first full guide to single-stranded RNA phages Reviews the history of molecular biology summarizing the role RNA phages in the development of the life sciences Demonstrates how RNA phage-derived products have resulted in nanotechnological applications Presents an up-to-date account of the role played by RNA phages in evolutionary and environmental studies
Book Synopsis Long Non-Coding RNAs by : Durdica Ugarkovic
Download or read book Long Non-Coding RNAs written by Durdica Ugarkovic and published by Springer Science & Business Media. This book was released on 2011-02-01 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: Long non-coding RNAs (lncRNAs), tentatively defined as ncRNAs of more than two hundred nucleotides in length, are characterized by the complexity and diversity of their sequences and mechanisms of action. Based on genome-wide studies, more than 3,300 of them exist, but to date only the limited number of functional lncRNAs have been identified and characterized. Nonetheless, lncRNAs have emerged as key molecules involved in the control of transcriptional and posttranscriptional gene regulatory pathways. They take part in the recruitment of chromatin modifying complexes and regulate splicing, localization, stability and translation of the target mRNAs. This book provides an overview of the rapidly advancing field of long ncRNAs, describing the epigenetic and non-epigenetic mechanisms by which they regulate various biological functions in model systems, from yeast to mammals. The role of ncRNAs in sex chromosome dosage compensation in flies and mammals is described, as well as their role in centromere and telomere biology. Long non-coding RNAs involved in environmental stress response and development are presented and their mechanisms of action discussed.
Book Synopsis Nucleocytoplasmic Transport by : Reiner Peters
Download or read book Nucleocytoplasmic Transport written by Reiner Peters and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Viruses and Apoptosis by : Covadonga Alonso
Download or read book Viruses and Apoptosis written by Covadonga Alonso and published by Springer Science & Business Media. This book was released on 2013-04-18 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: Using different viral models, molecular pathways regulated by viral genes and their role in the pathogenesis of infection are analyzed. The book also offers an update of known signaling pathways in apoptosis and their role in normal and infected cells. Special emphasis is given to molecular pathways underlying viral transformation and oncogenesis and how research in this area is opening opportunities in cancer therapy.
Book Synopsis Epigenetics and Chromatin by : Philippe Jeanteur
Download or read book Epigenetics and Chromatin written by Philippe Jeanteur and published by Springer Science & Business Media. This book was released on 2008-09-10 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epigenetics refers to heritable patterns of gene expression which do not depend on alterations of genomic DNA sequence. This book provides a state-of-the-art account of a few selected hot spots by scientists at the edge in this extremely active field. It puts special emphasis on two main streams of research. One is the role of post-translational modifications of proteins, mostly histones, on chromatin structure and accessibility. The other one deals with parental genomic imprinting, a process which allows to express a few selected genes from only one of the parental allele while extinguishing the other.
Download or read book The Nucleolus written by Mark O. J. Olson and published by Springer Science & Business Media. This book was released on 2011-09-15 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt: Within the past two decades, extraordinary new functions for the nucleolus have begun to appear, giving the field a new vitality and generating renewed excitement and interest. These new discoveries include both newly-discovered functions and aspects of its conventional role. The Nucleolus is divided into three parts: nucleolar structure and organization, the role of the nucleolus in ribosome biogenesis, and novel functions of the nucleolus.
Download or read book Centromere written by Durdica Ugarkovic and published by Springer Science & Business Media. This book was released on 2009-06-12 with total page 191 pages. Available in PDF, EPUB and Kindle. Book excerpt: The centromere is a chromosomal region that enables the accurate segregation of chromosomes during mitosis and meiosis. It holds sister chromatids together, and through its centromere DNA–protein complex known as the kinetochore binds spindle microtubules to bring about accurate chromosome movements. Despite this conserved function, centromeres exhibit dramatic difference in structure, size, and complexity. Extensive studies on centromeric DNA revealed its rapid evolution resulting often in significant difference even among closely related species. Such a plasticity of centromeric DNA could be explained by epigenetic c- trol of centromere function, which does not depend absolutely on primary DNA sequence. According to epigenetic centromere concept, which is thoroughly d- cussed by Tanya Panchenko and Ben Black in Chap. 1 of this book, centromere activation or inactivation might be caused by modifications of chromatin. Such acquired chromatin epigenetic modifications are then inherited from one cell di- sion to the next. Concerning centromere-specific chromatin modification, it is now evident that all centromeres contain a centromere specific histone H3 variant, CenH3, which replaces histone H3 in centromeric nucleosomes and provides a structural basis that epigenetically defines centromere and differentiates it from the surrounding chromatin. Recent insights into the CenH3 presented in this chapter add important mechanistic understanding of how centromere identity is initially established and subsequently maintained in every cell cycle.
Book Synopsis Aestivation by : Carlos Arturo Navas
Download or read book Aestivation written by Carlos Arturo Navas and published by Springer Science & Business Media. This book was released on 2010-01-12 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: Numerous animal species live in environments characterized by a seasonal reduction in the availability of water, which often but not always occurs when temperatures are highest. For many such animals, survival during the toughest season requires spending long periods of time in a rather inactive state known as aestivation. But aestivation is much more than remaining inactive. Successful aestivation requires the selection of a proper microhabitat, variable degrees of metabolic arrest and responsiveness to external stimuli, the ability to sense the proper time of year for emergence, the preservation of inactive tissue, and much more. So, aestivation involves a complex collection of behaviors, ecological associations and physiological adjustments that vary across species in their type, magnitude and course. This book seeks to explore the phenomenon of aestivation from different perspectives and levels of organization, ranging from microhabitat selection to genetic control of physiological adjustments. It brings together authors from across the world working on different systematic groups, approaches, and questions, but who are all ultimately working to better understand the complex issue of aestivation.
Book Synopsis Marine Toxins as Research Tools by : Nobuhiro Fusetani
Download or read book Marine Toxins as Research Tools written by Nobuhiro Fusetani and published by Springer Science & Business Media. This book was released on 2009-01-31 with total page 259 pages. Available in PDF, EPUB and Kindle. Book excerpt: Marine organisms produce a wide array of toxins, many of which are not only structurally unusual, but also show potent and interesting modes of action. Since the discovery of tetrodotoxin, a pufferfish toxin, as a potent and selective blocker of Na+ channels in 1964, it has been widely used as a research tool in pharmacological and physiological research. This has led to the identification of a number of important biological functions for Na+ channels. In recent years, much biological research has been carried out at molecular and cellular levels, and therefore selective inhibitors of enzymes and selective antagonist/agonists of receptors and channels have become increasingly important research tools. Accordingly, interest in using such compounds as reagents has increased. Marine toxins are some of the most popular research tools and have already contributed much to our understanding of biological processes and disease mechanisms.
Author :Alvaro Macieira-Coelho Publisher :Springer Science & Business Media ISBN 13 :3540691618 Total Pages :248 pages Book Rating :4.5/5 (46 download)
Book Synopsis Asymmetric Cell Division by : Alvaro Macieira-Coelho
Download or read book Asymmetric Cell Division written by Alvaro Macieira-Coelho and published by Springer Science & Business Media. This book was released on 2007-04-21 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cell biologists have recently come to understand that asymmetry of division is an important regulatory phenomenon in the fate of a cell. In adult organisms asymmetric divisions regulate the stem cell reservoir and are a source of the drift that contributes to aging. This book describes the phenomenon in different organisms and addresses its implications for the development of the organism, cell differentiation, human aging and the biology of cancers.
Download or read book Echinodermata written by Valeria Matranga and published by Springer Science & Business Media. This book was released on 2005-05-20 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: Members of the phylum Echinodermata are among the most familiar marine invertebrates. Forms such as the sea star have become virtually a symbol of sea life. Used in ancient oriental medicine as a source of bioactive compounds, sea cucumbers, sea stars and sea urchins are now used for the extraction and purification of cytotoxic, haemolytic, antiviral, antifungal, antifouling, antimicrobial and even anti-tumoural activities. In addition, of the five extant classes, sea urchins and sea cucumbers are important economic resources for current fishery and aquaculture. Molecular and cell biological techniques described in this book are, on the one hand, indicative of the improvements made over the years and, on the other, stress the need of their further exploitation for the sustainable production of bioactive compounds and their application in biomedicine.
Book Synopsis Molecular Basis of Symbiosis by : Jr̲g Overmann
Download or read book Molecular Basis of Symbiosis written by Jr̲g Overmann and published by Springer Science & Business Media. This book was released on 2006-01-10 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Extrusive Bacterial Ectosymbiosis of Ciliates.
Book Synopsis miRNA Regulation of the Translational Machinery by : Robert E. Rhoads
Download or read book miRNA Regulation of the Translational Machinery written by Robert E. Rhoads and published by Springer Science & Business Media. This book was released on 2009-10-20 with total page 122 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is dedicated to understanding how miRNAs affect translation. It includes chapters representing work in plants and Caenorhabditis elegans, the biological systems that originally led to the discovery of small interfering RNAs.
Book Synopsis Biosilica in Evolution, Morphogenesis, and Nanobiotechnology by : Werner E. G. Müller
Download or read book Biosilica in Evolution, Morphogenesis, and Nanobiotechnology written by Werner E. G. Müller and published by Springer Science & Business Media. This book was released on 2009-02-07 with total page 421 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lake Baikal is the oldest, deepest and most voluminous lake on Earth, comprising one fifth of the World’s unfrozen fresh water. It hosts the highest number of endemic animals recorded in any freshwater lake. Until recently it remained enigmatic why such a high diversity evolved in the isolated Lake Baikal. Focusing on the sponges (phylum Porifera) as an example, some answers are provided to fundamental questions on evolutionary forces. The characteristic feature of these animals is that they form their polymeric silicic acid skeleton enzymatically. This process is explored using modern molecular biological and cellular biological techniques to outline strategies to fabricate novel materials applicable in biomedicine and nanooptics.
Author :Alvaro Macieira-Coelho Publisher :Springer Science & Business Media ISBN 13 :9783540250098 Total Pages :270 pages Book Rating :4.2/5 (5 download)
Book Synopsis Developmental Biology of Neoplastic Growth by : Alvaro Macieira-Coelho
Download or read book Developmental Biology of Neoplastic Growth written by Alvaro Macieira-Coelho and published by Springer Science & Business Media. This book was released on 2005-05-20 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book, tumour growth is perceived as a deviation from the normal development of the human organism. The molecular, cellular, and tissue determinants of different tumours are discussed showing that each is a different disease, often corresponding to a particular developmental stage. The natural history of several cancers illustrates how clinical incidence can be just the visible part of the iceberg, while the first changes at the tissue level sometimes occur several years before tumour growth becomes manifest. Several mechanisms are proposed to explain the distribution of cancers during the human life span and the decline of the incidence of cancers during human senescence.
