RNA 3D Structure Analysis and Prediction

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Publisher : Springer Science & Business Media
ISBN 13 : 3642257402
Total Pages : 402 pages
Book Rating : 4.6/5 (422 download)

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Book Synopsis RNA 3D Structure Analysis and Prediction by : Neocles Leontis

Download or read book RNA 3D Structure Analysis and Prediction written by Neocles Leontis and published by Springer Science & Business Media. This book was released on 2012-06-05 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the dramatic increase in RNA 3D structure determination in recent years, we now know that RNA molecules are highly structured. Moreover, knowledge of RNA 3D structures has proven crucial for understanding in atomic detail how they carry out their biological functions. Because of the huge number of potentially important RNA molecules in biology, many more than can be studied experimentally, we need theoretical approaches for predicting 3D structures on the basis of sequences alone. This volume provides a comprehensive overview of current progress in the field by leading practitioners employing a variety of methods to model RNA 3D structures by homology, by fragment assembly, and by de novo energy and knowledge-based approaches.

RNA Structure Determination

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Publisher : Humana
ISBN 13 : 9781493964314
Total Pages : 0 pages
Book Rating : 4.9/5 (643 download)

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Book Synopsis RNA Structure Determination by : Douglas H. Turner

Download or read book RNA Structure Determination written by Douglas H. Turner and published by Humana. This book was released on 2016-09-24 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides protocols and procedures for determining and modeling RNA structure. Chapters guide the reader through protocols for RNA secondary structure prediction, single sequence modeling, Crumple, RNAstructure to model conserved secondary structures with multiple homologs, the prediction of bimolecular secondary structures with RNAstructure, STarMir, protocols for structure mapping, mapping data to constrain or restrain RNA secondary structure prediction with RNAstructure, unassigned NMR resonances, modeling protocols for Rosetta FARFAR, RNAComposer , ModeRNA, and MC-Fold. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and Practical, RNA Structure Determination: Methods and Protocols aims to ensure successful results in the further study of this vital field.

RNA Structure Prediction

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Publisher : Springer Nature
ISBN 13 : 1071627686
Total Pages : 304 pages
Book Rating : 4.0/5 (716 download)

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Book Synopsis RNA Structure Prediction by : Risa Karakida Kawaguchi

Download or read book RNA Structure Prediction written by Risa Karakida Kawaguchi and published by Springer Nature. This book was released on 2023-01-27 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores recent progress in RNA secondary, tertiary structure prediction, and its application from an expansive point of view. Because of advancements in experimental protocols and devices, the integration of new types of data as well as new analysis techniques is necessary, and this volume discusses additional topics that are closely related to RNA structure prediction, such as the detection of structure-disrupting mutations, high-throughput structure analysis, and 3D structure design. Written for the highly successful Methods in Molecular Biology series, chapters feature the kind of detailed implementation advice that leads to quality research results. Authoritative and practical, RNA Structure Prediction serves as a valuable guide for both experimental and computational RNA researchers.

RNA Sequence, Structure, and Function: Computational and Bioinformatic Methods

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Publisher : Humana
ISBN 13 : 9781627037082
Total Pages : 0 pages
Book Rating : 4.0/5 (37 download)

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Book Synopsis RNA Sequence, Structure, and Function: Computational and Bioinformatic Methods by : Jan Gorodkin

Download or read book RNA Sequence, Structure, and Function: Computational and Bioinformatic Methods written by Jan Gorodkin and published by Humana. This book was released on 2014-03-18 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The existence of genes for RNA molecules not coding for proteins (ncRNAs) has been recognized since the 1950's, but until recently, aside from the critically important ribosomal and transfer RNA genes, most focus has been on protein coding genes. However, a long series of striking discoveries, from RNA's ability to carry out catalytic function, to discovery of riboswitches, microRNAs and other ribo-regulators performing critical tasks in essentially all living organisms, has created a burgeoning interest in this primordial component of the biosphere. However, the structural characteristics and evolutionary constraints on RNA molecules are very different from those of proteins, necessitating development of a completely new suite of informatic tools to address these challenges. In RNA Sequence, Structure, Function: Computational and Bioinformatic Methods, expert researchers in the field describe a substantial and relevant fraction of these methodologies from both practical and computational/algorithmic perspectives. Focusing on both of these directions addresses both the biologist interested in knowing more about RNA bioinformatics as well as the bioinformaticist interested in more detailed aspects of the algorithms. Written in the highly successful Methods in Molecular Biology series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results. Thorough and intuitive, RNA Sequence, Structure, Function: Computational and Bioinformatic Methods aids scientists in continuing to study key methods and principles of RNA bioinformatics.

RNA Structure and Folding

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Author :
Publisher : Walter de Gruyter
ISBN 13 : 3110284952
Total Pages : 432 pages
Book Rating : 4.1/5 (12 download)

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Book Synopsis RNA Structure and Folding by : Dagmar Klostermeier

Download or read book RNA Structure and Folding written by Dagmar Klostermeier and published by Walter de Gruyter. This book was released on 2013-10-14 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: While structure-function relationships of proteins have been studied for a long time, structural studies of RNA face additional challenges. Nevertheless, with the continuous discovery of novel RNA molecules with key cellular functions and of novel pathways and interaction networks, the need for structural information of RNA is still increasing. This volume provides an introduction into techniques to assess structure and folding of RNA. Each chapter explains the theoretical background of one technique, and illustrates possibilities and limitations in selected application examples.

Bioinformatics in Rice Research

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Publisher : Springer Nature
ISBN 13 : 9811639930
Total Pages : 609 pages
Book Rating : 4.8/5 (116 download)

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Book Synopsis Bioinformatics in Rice Research by : Manoj Kumar Gupta

Download or read book Bioinformatics in Rice Research written by Manoj Kumar Gupta and published by Springer Nature. This book was released on 2021-09-24 with total page 609 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an up-to-date review of classic and advanced bioinformatics approaches and their utility in rice research. It summarizes databases and tools for analyzing DNA, proteins and gene expression profiles, mapping genetic variations, annotation of protein and RNA molecules, phylogenetic analysis, and pathway enrichment. In addition, it presents high-throughput technologies that are widely used to provide deep insights into the genetic architecture of important traits in the rice genome. The book subsequently discusses techniques for identifying RNA-protein, DNA-protein interactions, and molecular markers, including SNP and microsatellites, in the contexts of rice breeding and genetics. Lastly, it explores various tools that are used to identify and characterize non-coding RNA in rice and their potential role in rice research.

Encyclopedia of Algorithms

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Publisher : Springer Science & Business Media
ISBN 13 : 0387307702
Total Pages : 1200 pages
Book Rating : 4.3/5 (873 download)

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Book Synopsis Encyclopedia of Algorithms by : Ming-Yang Kao

Download or read book Encyclopedia of Algorithms written by Ming-Yang Kao and published by Springer Science & Business Media. This book was released on 2008-08-06 with total page 1200 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of Springer’s renowned Major Reference Works, this awesome achievement provides a comprehensive set of solutions to important algorithmic problems for students and researchers interested in quickly locating useful information. This first edition of the reference focuses on high-impact solutions from the most recent decade, while later editions will widen the scope of the work. All entries have been written by experts, while links to Internet sites that outline their research work are provided. The entries have all been peer-reviewed. This defining reference is published both in print and on line.

RNA Structure Determination: Methods and Protocols

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Publisher : Methods in Molecular Biology
ISBN 13 : 9781493981984
Total Pages : 300 pages
Book Rating : 4.9/5 (819 download)

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Book Synopsis RNA Structure Determination: Methods and Protocols by : Douglas H. Turner

Download or read book RNA Structure Determination: Methods and Protocols written by Douglas H. Turner and published by Methods in Molecular Biology. This book was released on 2018-10-08 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides protocols and procedures for determining and modeling RNA structure. Chapters guide the reader through protocols for RNA secondary structure prediction, single sequence modeling, Crumple, RNAstructure to model conserved secondary structures with multiple homologs, the prediction of bimolecular secondary structures with RNAstructure, STarMir, protocols for structure mapping, mapping data to constrain or restrain RNA secondary structure prediction with RNAstructure, unassigned NMR resonances, modeling protocols for Rosetta FARFAR, RNAComposer, ModeRNA, and MC-Fold. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and Practical, RNA Structure Determination: Methods and Protocols aims to ensure successful results in the further study of this vital field.

RNA Biochemistry and Biotechnology

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Publisher : Springer Science & Business Media
ISBN 13 : 9780792358619
Total Pages : 718 pages
Book Rating : 4.3/5 (586 download)

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Book Synopsis RNA Biochemistry and Biotechnology by : Jan Barciszewski

Download or read book RNA Biochemistry and Biotechnology written by Jan Barciszewski and published by Springer Science & Business Media. This book was released on 1999-08-31 with total page 718 pages. Available in PDF, EPUB and Kindle. Book excerpt: RNA Biochemistry and Biotechnology describes various aspects of nucleic acid and protein structure, mainly RNA structure and proteins, interacting with specific RNA species. Papers deal with DNA protein interactions, telomerase, aminoacyl-tRNA synthetases, elongation factor Tu, DNA repair, RNA structure, NMR technology, RNA aptamer interaction of biological macromolecules with metal ions. Two papers deal with theoretical aspects of RNA structure production and computer modelling. Many papers describe the possibility of commercial application of RNA biotechnology. One article discusses the impact of direct democracy on basic science supporting biotechnology. Readership: Advanced graduate students, Ph.D. students and young scientists as well as specialists in the field.

RNA Folding

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Publisher : Springer Nature
ISBN 13 : 1071635190
Total Pages : 407 pages
Book Rating : 4.0/5 (716 download)

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Book Synopsis RNA Folding by : Ronny Lorenz

Download or read book RNA Folding written by Ronny Lorenz and published by Springer Nature. This book was released on with total page 407 pages. Available in PDF, EPUB and Kindle. Book excerpt:

RNA Folding

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Publisher : Humana
ISBN 13 : 9781493960583
Total Pages : 0 pages
Book Rating : 4.9/5 (65 download)

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Book Synopsis RNA Folding by : Christina Waldsich

Download or read book RNA Folding written by Christina Waldsich and published by Humana. This book was released on 2016-08-23 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Focusing on in vitro and intracellular RNA structure formation, RNA Folding: Methods and Protocols provides a comprehensive collection of experimental protocols which are suitable to dissect RNA folding pathways and to characterize the structure of RNA folding intermediates at nucleotide or even atomic resolution. The presented techniques include powerful tools with a long tradition in RNA research as well as more advanced, novel methods, thus the methods span multiple disciplines, including molecular biology, biochemistry, biophysics, and computational biology. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Practical and authoritative, RNA Folding: Methods and Protocols serves as a vital reference for researchers attempting to gain insights into the secrets of this astounding macromolecule.

Intelligent Computing Theories and Application

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Publisher : Springer
ISBN 13 : 3319959301
Total Pages : 932 pages
Book Rating : 4.3/5 (199 download)

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Book Synopsis Intelligent Computing Theories and Application by : De-Shuang Huang

Download or read book Intelligent Computing Theories and Application written by De-Shuang Huang and published by Springer. This book was released on 2018-08-08 with total page 932 pages. Available in PDF, EPUB and Kindle. Book excerpt: This two-volume set LNCS 10954 and LNCS 10955 constitutes - in conjunction with the volume LNAI 10956 - the refereed proceedings of the 14th International Conference on Intelligent Computing, ICIC 2018, held in Wuhan, China, in August 2018. The 275 full papers and 72 short papers of the three proceedings volumes were carefully reviewed and selected from 632 submissions. The papers are organized in topical sections such as Neural Networks.- Pattern Recognition.- Image Processing.- Intelligent Computing in Robotics.- Intelligent Control and Automation.- Intelligent Data Analysis and Prediction.- Fuzzy Theory and Algorithms.- Supervised Learning.- Unsupervised Learning.- Kernel Methods and Supporting Vector Machines.- Knowledge Discovery and Data Mining.- Natural Language Processing and Computational Linguistics.- Gene Expression Array Analysis.- Systems Biology.- Computational Genomics.- Computational Proteomics.- Gene Regulation Modeling and Analysis.- Protein-Protein Interaction Prediction.- Next-Gen Sequencing and Metagenomics.- Structure Prediction and Folding.- Evolutionary Optimization for Scheduling.- High-Throughput Biomedical Data Integration and Mining.- Machine Learning Algorithms and Applications.- Heuristic Optimization Algorithms for Real-World Applications.- Evolutionary Multi-Objective Optimization and Its Applications.- Swarm Evolutionary Algorithms for Scheduling and Combinatorial.- Optimization.- Swarm Intelligence and Applications in Combinatorial Optimization.- Advances in Metaheuristic Optimization Algorithm.- Advances in Image Processing and Pattern Recognition Techniques.- AI in Biomedicine.- Bioinformatics.- Biometrics Recognition.- Information Security.- Virtual Reality and Human-Computer Interaction.- Healthcare Informatics Theory and Methods.- Intelligent Computing in Computer Vision.- Intelligent Agent and Web Applications.- Reinforcement Learning.- Machine Learning.- Modeling, Simulation, and Optimization of Biological Systems.- Biomedical Data Modeling and Mining.- Cheminformatics.- Intelligent Computing in Computational Biology.- Protein Structure and Function Prediction.- Biomarker Discovery.- Hybrid Computational Intelligence: Theory and Application in Bioinformatics, Computational Biology and Systems Biology.- IoT and Smart Data.- Intelligent Systems and Applications for Bioengineering.- Evolutionary Optimization: Foundations and Its Applications to Intelligent Data Analytics.- Protein and Gene Bioinformatics: Analysis, Algorithms and Applications.

Handbook of RNA Biochemistry

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Publisher : John Wiley & Sons
ISBN 13 : 3527327762
Total Pages : 1370 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Handbook of RNA Biochemistry by : Roland K. Hartmann

Download or read book Handbook of RNA Biochemistry written by Roland K. Hartmann and published by John Wiley & Sons. This book was released on 2015-06-22 with total page 1370 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of a highly acclaimed handbook and ready reference. Unmatched in its breadth and quality, around 100 specialists from all over the world share their up-to-date expertise and experiences, including hundreds of protocols, complete with explanations, and hitherto unpublished troubleshooting hints. They cover all modern techniques for the handling, analysis and modification of RNAs and their complexes with proteins. Throughout, they bear the practising bench scientist in mind, providing quick and reliable access to a plethora of solutions for practical questions of RNA research, ranging from simple to highly complex. This broad scope allows the treatment of specialized methods side by side with basic biochemical techniques, making the book a real treasure trove for every researcher experimenting with RNA.

Structural Bioinformatics

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Publisher : John Wiley & Sons
ISBN 13 : 1118210565
Total Pages : 1105 pages
Book Rating : 4.1/5 (182 download)

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Book Synopsis Structural Bioinformatics by : Jenny Gu

Download or read book Structural Bioinformatics written by Jenny Gu and published by John Wiley & Sons. This book was released on 2011-09-20 with total page 1105 pages. Available in PDF, EPUB and Kindle. Book excerpt: Structural Bioinformatics was the first major effort to show the application of the principles and basic knowledge of the larger field of bioinformatics to questions focusing on macromolecular structure, such as the prediction of protein structure and how proteins carry out cellular functions, and how the application of bioinformatics to these life science issues can improve healthcare by accelerating drug discovery and development. Designed primarily as a reference, the first edition nevertheless saw widespread use as a textbook in graduate and undergraduate university courses dealing with the theories and associated algorithms, resources, and tools used in the analysis, prediction, and theoretical underpinnings of DNA, RNA, and proteins. This new edition contains not only thorough updates of the advances in structural bioinformatics since publication of the first edition, but also features eleven new chapters dealing with frontier areas of high scientific impact, including: sampling and search techniques; use of mass spectrometry; genome functional annotation; and much more. Offering detailed coverage for practitioners while remaining accessible to the novice, Structural Bioinformatics, Second Edition is a valuable resource and an excellent textbook for a range of readers in the bioinformatics and advanced biology fields. Praise for the previous edition: "This book is a gold mine of fundamental and practical information in an area not previously well represented in book form." —Biochemistry and Molecular Education "... destined to become a classic reference work for workers at all levels in structural bioinformatics...recommended with great enthusiasm for educators, researchers, and graduate students." —BAMBED "...a useful and timely summary of a rapidly expanding field." —Nature Structural Biology "...a terrific job in this timely creation of a compilation of articles that appropriately addresses this issue." —Briefings in Bioinformatics

Bacterial Regulatory RNA

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Publisher : Humana Press
ISBN 13 : 9781617799488
Total Pages : 0 pages
Book Rating : 4.7/5 (994 download)

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Book Synopsis Bacterial Regulatory RNA by : Kenneth C. Keiler

Download or read book Bacterial Regulatory RNA written by Kenneth C. Keiler and published by Humana Press. This book was released on 2012-06-28 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The discovery of wide-spread RNA-based regulation in bacteria has led to new evaluations of the importance of bacterial regulatory RNA in every aspect of bacterial physiology. In Bacteria Regulatory RNA: Methods and Protocols, expert researchers in the field detail many of the methods which are now commonly used to study bacterial regulatory RNA. These include methods and techniques to identify regulatory RNAs, characterizing the function and expression of regulatory RNAs in bacterial cells, RNA structure prediction, and interactions between regulatory RNAs and proteins. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Bacteria Regulatory RNA: Methods and Protocols seeks to aid scientists in the further study of bacterial regulatory RNA.

The RNA World

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Publisher :
ISBN 13 :
Total Pages : 744 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The RNA World by : Raymond F. Gesteland

Download or read book The RNA World written by Raymond F. Gesteland and published by . This book was released on 1999 with total page 744 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Biological Sequence Analysis

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Publisher : Cambridge University Press
ISBN 13 : 113945739X
Total Pages : 372 pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis Biological Sequence Analysis by : Richard Durbin

Download or read book Biological Sequence Analysis written by Richard Durbin and published by Cambridge University Press. This book was released on 1998-04-23 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: Probabilistic models are becoming increasingly important in analysing the huge amount of data being produced by large-scale DNA-sequencing efforts such as the Human Genome Project. For example, hidden Markov models are used for analysing biological sequences, linguistic-grammar-based probabilistic models for identifying RNA secondary structure, and probabilistic evolutionary models for inferring phylogenies of sequences from different organisms. This book gives a unified, up-to-date and self-contained account, with a Bayesian slant, of such methods, and more generally to probabilistic methods of sequence analysis. Written by an interdisciplinary team of authors, it aims to be accessible to molecular biologists, computer scientists, and mathematicians with no formal knowledge of the other fields, and at the same time present the state-of-the-art in this new and highly important field.