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Rna Structure And Dynamics
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Book Synopsis RNA Structure and Dynamics by : Jienyu Ding
Download or read book RNA Structure and Dynamics written by Jienyu Ding and published by Springer Nature. This book was released on 2022-10-13 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a wide spectrum of multidisciplinary approaches for studying RNA structure and dynamics, including detailed accounts of experimental and computational procedures. Chapters guide readers through cryo-electron microscopy, crystallography, isothermal titration calorimetry, small angle X-ray scattering, single-molecule Förster Energy transfer, X-ray free electron laser, atomic force microscopy, computational simulation, and prediction. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, RNA Structure and Dynamics aims to be a foundation for future studies and to be a source of inspiration for new investigations in the field.
Book Synopsis RNA 3D Structure Analysis and Prediction by : Neocles Leontis
Download or read book RNA 3D Structure Analysis and Prediction written by Neocles Leontis and published by Springer Science & Business Media. This book was released on 2012-06-05 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the dramatic increase in RNA 3D structure determination in recent years, we now know that RNA molecules are highly structured. Moreover, knowledge of RNA 3D structures has proven crucial for understanding in atomic detail how they carry out their biological functions. Because of the huge number of potentially important RNA molecules in biology, many more than can be studied experimentally, we need theoretical approaches for predicting 3D structures on the basis of sequences alone. This volume provides a comprehensive overview of current progress in the field by leading practitioners employing a variety of methods to model RNA 3D structures by homology, by fragment assembly, and by de novo energy and knowledge-based approaches.
Download or read book Structure and Dynamics of RNA written by and published by . This book was released on 1986-10-31 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :P. H. van Knippenberg Publisher :Springer Science & Business Media ISBN 13 :1468451731 Total Pages :335 pages Book Rating :4.4/5 (684 download)
Book Synopsis Structure and Dynamics of RNA by : P. H. van Knippenberg
Download or read book Structure and Dynamics of RNA written by P. H. van Knippenberg and published by Springer Science & Business Media. This book was released on 2013-03-08 with total page 335 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains contributions from the speakers at the NATO Advanced Research Workshop on "3D 5tructure and Dynamics of RNA", which was held in Renesse, The Netherlands, 21 - 24 August, 1985. Two major developments have determined the progress of nucleic acid research during the last decade. First, manipulation of genetic material by recombinant DNA methodology has enabled detailed studies of the function of nucleic acids in vivo. 5econd, the use of powerful physical methods, such as X-ray diffraction and nuclear magnetic resonance spectroscopy, in the study of biomacromolecules has provided information regarding the structure and the dynamics of nucleic acids. Both developments were enabled by the advance of synthetic methods that allow preparation of nucleic acid molecules of required sequence and length. The basic understanding of nucleic acid function will ultimately depend on a close collaboration between molecular biologists and biophy sicists. In the case of RNA, the ground rules for the formation of secondary structure have been derived from physical studies of oligoribonucleotides. Powerfull spectroscopic techniques have revealed more details of ~~A structure including novel conformations (e.g. left-handed Z-RNA). A wealth of information has been obtained by studying the relatively small transfer RNA molecules. A few of these RNAs have been crystallized, enabling determination of their three-dimensional structure. It has become apparent that "non-classical" basepairing between distal nucleotides gives rise to tertiary interactions, determining the overall shape of the molecule.
Book Synopsis RNA 3D Structure Analysis and Prediction by : Neocles Leontis
Download or read book RNA 3D Structure Analysis and Prediction written by Neocles Leontis and published by Springer Science & Business Media. This book was released on 2012-06-05 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the dramatic increase in RNA 3D structure determination in recent years, we now know that RNA molecules are highly structured. Moreover, knowledge of RNA 3D structures has proven crucial for understanding in atomic detail how they carry out their biological functions. Because of the huge number of potentially important RNA molecules in biology, many more than can be studied experimentally, we need theoretical approaches for predicting 3D structures on the basis of sequences alone. This volume provides a comprehensive overview of current progress in the field by leading practitioners employing a variety of methods to model RNA 3D structures by homology, by fragment assembly, and by de novo energy and knowledge-based approaches.
Book Synopsis RNA Trafficking and Nuclear Structure Dynamics by : Philippe Jeanteur
Download or read book RNA Trafficking and Nuclear Structure Dynamics written by Philippe Jeanteur and published by Springer. This book was released on 2007-11-03 with total page 161 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume explores nuclear structure and trafficking involving or relevant to RNA and RNPs. Topics include advances and current problems in the structural organization of different subnuclear compartments, Cajal bodies and gems, speckles containing splicing factors, and PML bodies characteristic of ProMyelocytic leukemia. The book also describes the dynamic aspects of RNA trafficking and the latest technologies for live cell imaging of mRNA.
Book Synopsis Biophysical, Chemical, and Functional Probes of RNA Structure, Interactions and Folding: Part B by : Daniel Herschlag
Download or read book Biophysical, Chemical, and Functional Probes of RNA Structure, Interactions and Folding: Part B written by Daniel Herschlag and published by Academic Press. This book was released on 2009-11-16 with total page 567 pages. Available in PDF, EPUB and Kindle. Book excerpt: This MIE volume provides laboratory techniques that aim to predict the structure of a protein which can have tremendous implications ranging from drug design, to cellular pathways and their dynamics, to viral entry into cells. Expert researchers introduce the most advanced technologies and techniques in protein structure and folding Includes techniques on tiling assays
Book Synopsis Biophysical, Chemical, and Functional Probes of RNA Structure, Interactions and Folding: Part A by : Daniel Herschlag
Download or read book Biophysical, Chemical, and Functional Probes of RNA Structure, Interactions and Folding: Part A written by Daniel Herschlag and published by Academic Press. This book was released on 2009-11-16 with total page 491 pages. Available in PDF, EPUB and Kindle. Book excerpt: This MIE volume provides laboratory techniques that aim to predict the structure of a protein which can have tremendous implications ranging from drug design, to cellular pathways and their dynamics, to viral entry into cells. Expert researchers introduce the most advanced technologies and techniques in protein structure and folding Includes techniques on tiling assays
Book Synopsis Structures of Large RNA Molecules and Their Complexes by :
Download or read book Structures of Large RNA Molecules and Their Complexes written by and published by Academic Press. This book was released on 2015-06-06 with total page 675 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods in RNA folding and dynamics, RNA-protein interactions and large RNPs. Continues the legacy of this premier serial with quality chapters on structures of large RNA molecules and their complexes
Book Synopsis RNA Structure and Folding by : Dagmar Klostermeier
Download or read book RNA Structure and Folding written by Dagmar Klostermeier and published by Walter de Gruyter. This book was released on 2013-10-14 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: While structure-function relationships of proteins have been studied for a long time, structural studies of RNA face additional challenges. Nevertheless, with the continuous discovery of novel RNA molecules with key cellular functions and of novel pathways and interaction networks, the need for structural information of RNA is still increasing. This volume provides an introduction into techniques to assess structure and folding of RNA. Each chapter explains the theoretical background of one technique, and illustrates possibilities and limitations in selected application examples.
Book Synopsis Ribosomes Structure, Function, and Dynamics by : Marina V. Rodnina
Download or read book Ribosomes Structure, Function, and Dynamics written by Marina V. Rodnina and published by Springer Science & Business Media. This book was released on 2011-12-10 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: The ribosome is a macromolecular machine that synthesizes proteins with a high degree of speed and accuracy. Our present understanding of its structure, function and dynamics is the result of six decades of research. This book collects over 40 articles based on the talks presented at the 2010 Ribosome Meeting, held in Orvieto, Italy, covering all facets of the structure and function of the ribosome. New high-resolution crystal structures of functional ribosome complexes and cryo-EM structures of translating ribosomes are presented, while partial reactions of translation are examined in structural and mechanistic detail, featuring translocation as a most dynamic process. Mechanisms of initiation, both in bacterial and eukaryotic systems, translation termination, and novel details of the functions of the respective factors are described. Structure and interactions of the nascent peptide within, and emerging from, the ribosomal peptide exit tunnel are addressed in several articles. Structural and single-molecule studies reveal a picture of the ribosome exhibiting the energy landscape of a processive Brownian machine. The collection provides up-to-date reviews which will serve as a source of essential information for years to come.
Download or read book RNA written by D. Söll and published by Elsevier. This book was released on 2001-12-03 with total page 355 pages. Available in PDF, EPUB and Kindle. Book excerpt: This publication summarizes the current status of our understanding of RNA, with particular emphasis on the chemistry of this key biological molecule. The various RNAs covered are messenger RNA, ribosomal RNA, transfer RNA and RNA enzymes (ribozymes). The different chapters detail biophysical and chemical methods to investigate RNA structure and function, the synthesis of native and modified RNAs and the latest advances in our understanding of the vast array of biological processes in which RNA is involved.
Book Synopsis Single-molecule FRET Guided Modeling of RNA Structure and Dynamics by : Fabio Steffen
Download or read book Single-molecule FRET Guided Modeling of RNA Structure and Dynamics written by Fabio Steffen and published by . This book was released on 2020 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Nucleic Acids by : Victor A. Bloomfield
Download or read book Nucleic Acids written by Victor A. Bloomfield and published by Sterling Publishing Company. This book was released on 2000-04-17 with total page 854 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing a comprehensive account of the structures and physical chemistry properties of nucleic acids, with special emphasis on biological function, this text has been organized to meet the needs of those who have only a basic understanding of physical chemistry and molecular biology.
Download or read book RNA Folding written by Ronny Lorenz and published by Springer Nature. This book was released on with total page 407 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Principles of Nuclear Magnetism by : A. Abragam
Download or read book The Principles of Nuclear Magnetism written by A. Abragam and published by Oxford University Press. This book was released on 1961 with total page 666 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Principles of Nuclear Magnetism
Book Synopsis New Chemical Approaches for the Investigation of RNA Structural Dynamics by : Steven George Chaulk
Download or read book New Chemical Approaches for the Investigation of RNA Structural Dynamics written by Steven George Chaulk and published by . This book was released on 2001 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: RNA is intimately involved in many vital biological processes involved in gene expression. Investigation of the role of RNA in these processes is complicated by structural dynamics during these processes. New approaches for the characterization of structural dynamics of RNA are necessary for a complete understanding of the function of RNA in these systems. This thesis describes new chemical approaches for investigating RNA structural dynamics. Caging of the RNA 2' hydroxyl allows control of RNA reactivity or structure associated with the functionality. This strategy was used to separate spliceosome assembly from spliceosome catalysis. The second approach, footprinting with peroxynitrous acid, allows the detection of folded RNA structures. Application of this reagent in a kinetic footprinting experiment allows the detection of structure formation or change in real time. This methodology was used to characterize the folding pathway of the Group I ribozyme. A third set of experiments established the suitability of 'N'-hydroxypyridine-2(1' H')-thione as a source of hydroxyl radicals for protection footprinting of RNA structure. Extension of these methodologies should provide valuable information regarding the structure and function of RNA in diverse systems.
