Rna Metabolism In Mitochondria

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RNA Metabolism in Mitochondria

Author : Jorge Cruz-Reyes
Publisher : Springer
ISBN 13 : 3319781901
Total Pages : 255 pages
Book Rating : 4.3/5 (197 download)

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Book Synopsis RNA Metabolism in Mitochondria by : Jorge Cruz-Reyes

Download or read book RNA Metabolism in Mitochondria written by Jorge Cruz-Reyes and published by Springer. This book was released on 2018-06-12 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume focuses on mitochondrial RNA metabolism, emphasizing recent discoveries and technological advances in this fast moving area that increase our understanding of mitochondrial gene function. Topics addressed include the interplay of mitochondria with the nucleus and cytosol, structure-function connections, and relevance to human disease. Mitochondria are the powerhouses of the cell, and a great deal is known about mitochondrial energy metabolism. Less well known is the plethora of amazing mechanisms that have evolved to control expression of mitochondrial genomes. Several RNA processes and machineries in protozoa, plants, flies and humans are discussed, including: transcription and RNA polymerase mechanism; tRNA processing of 5′ and 3′ ends; mRNA maturation by nucleotide insertion/deletion editing and by RNA splicing; mRNA stability; and RNA import. Specialized factors and ribonucleoproteins (RNPs) examined include pentatricopeptide repeat (PPR) proteins, RNase P, polymerases, helicases, nucleases, editing and repair enzymes. Remarkable features of these processes and factors are either not found outside mitochondria, differ substantially among eukaryotic lineages, or are unique in biology.

Mitochondrial Gene Expression

Author :
Publisher :
ISBN 13 : 9781071608340
Total Pages : pages
Book Rating : 4.6/5 (83 download)

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Book Synopsis Mitochondrial Gene Expression by :

Download or read book Mitochondrial Gene Expression written by and published by . This book was released on 2021 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

The RNA Metabolism of Nucleoli and Mitochondria in Mammalian Cells

Author :
Publisher :
ISBN 13 :
Total Pages : 12 pages
Book Rating : 4.:/5 (929 download)

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Book Synopsis The RNA Metabolism of Nucleoli and Mitochondria in Mammalian Cells by :

Download or read book The RNA Metabolism of Nucleoli and Mitochondria in Mammalian Cells written by and published by . This book was released on 1969 with total page 12 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Studies on RNA Metabolism in HeLa Mitochondria

Author : Robert Allen Gelfand
Publisher :
ISBN 13 :
Total Pages : 424 pages
Book Rating : 4.:/5 (436 download)

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Book Synopsis Studies on RNA Metabolism in HeLa Mitochondria by : Robert Allen Gelfand

Download or read book Studies on RNA Metabolism in HeLa Mitochondria written by Robert Allen Gelfand and published by . This book was released on 1980 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt:

RNA Metabolism in Trypanosomes

Author : Albrecht Bindereif
Publisher : Springer Science & Business Media
ISBN 13 : 3642286879
Total Pages : 270 pages
Book Rating : 4.6/5 (422 download)

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Book Synopsis RNA Metabolism in Trypanosomes by : Albrecht Bindereif

Download or read book RNA Metabolism in Trypanosomes written by Albrecht Bindereif and published by Springer Science & Business Media. This book was released on 2012-06-12 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: Trypanosomes are unicellular protozoa of ancient evolutionary origin that are responsible for several tropical diseases, such as African sleeping sickness. Over the last few decades, research in trypanosome biology has revealed many unique and fascinating features, many of which have helped to establish new paradigms in other biological systems. This applies in particular to studies in gene expression and regulation, which benefit enormously from the trypanosome genome projects and from the new genome-wide approaches recently introduced in trypanosome research. This volume covers the most important aspects of biosynthesis, processing, and functions of RNA in trypanosomes, ranging from transcription to RNA editing, mRNA splicing/translation/turnover, processing of transfer and ribosomal RNA, RNA interference, and current transcriptome-wide analyses. Recent progress in RNA-focused research in trypanosomatids promises to yield novel insights into trypanosome-specific features, as well as to reveal in the process new potential therapeutic strategies for combating these parasitic diseases.

RNA Metabolism in Neurodegenerative Diseases

Author : Rita Sattler
Publisher : Springer
ISBN 13 : 331989689X
Total Pages : 321 pages
Book Rating : 4.3/5 (198 download)

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Book Synopsis RNA Metabolism in Neurodegenerative Diseases by : Rita Sattler

Download or read book RNA Metabolism in Neurodegenerative Diseases written by Rita Sattler and published by Springer. This book was released on 2018-06-18 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: It has become evident over the last years that abnormalities in RNA processing play a fundamental part in the pathogenesis of neurodegenerative diseases. Cellular viability depends on proper regulation of RNA metabolism and subsequent protein synthesis, which requires the interplay of many processes including transcription, pre--‐mRNA splicing, mRNA editing as well as mRNA stability, transport and translation. Dysfunction in any of these processes, often caused by mutations in the coding and non--‐ coding RNAs, can be very destructive to the cellular environment and consequently impair neural viability. The result of this RNA toxicity can lead to a toxic gain of function or a loss of function, depending on the nature of the mutation. For example, in repeat expansion disorders, such as the newly discovered hexanucleotide repeat expansion in theC9orf72 gene found in amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), a toxic gain of function leads to the formation of RNA foci and the sequestration of RNA binding proteins (RBPs). This in return leads to a loss of function of those RBPs, which is hypothesized to play a significant part in the disease progression of ALS and FTD. Other toxicities arising from repeat expansions are the formation of RNA foci, bi--‐directional transcription and production of repeat associated non--‐ATG (RAN) translation products. This book will touch upon most of these disease mechanisms triggered by aberrant RNA metabolism and will therefore provide a broad perspective of the role of RNA processing and its dysfunction in a variety of neurodegenerative disorders, including ALS, FTD, Alzheimer’s disease, Huntington’s disease, spinal muscular atrophy, myotonic dystrophy and ataxias. The proposed authors are leading scientists in the field and are expected to not only discuss their own work, but to be inclusive of historic as well as late breaking discoveries. The compiled chapters will therefore provide a unique collection of novel studies and hypotheses aimed to describe the consequences of altered RNA processing events and its newest molecular players and pathways.

Nuclear and Mitochondrial Mutations Affecting Mitochondrial RNA Metabolism

Author : Heather Miller Conrad
Publisher :
ISBN 13 :
Total Pages : 712 pages
Book Rating : 4.:/5 (186 download)

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Book Synopsis Nuclear and Mitochondrial Mutations Affecting Mitochondrial RNA Metabolism by : Heather Miller Conrad

Download or read book Nuclear and Mitochondrial Mutations Affecting Mitochondrial RNA Metabolism written by Heather Miller Conrad and published by . This book was released on 1987 with total page 712 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Molecular Biology of the Cell

Author :
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)

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Book Synopsis Molecular Biology of the Cell by :

Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Genetics and Biotechnology

Author : Ulrich Kück
Publisher : Springer Science & Business Media
ISBN 13 : 3662103648
Total Pages : 372 pages
Book Rating : 4.6/5 (621 download)

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Book Synopsis Genetics and Biotechnology by : Ulrich Kück

Download or read book Genetics and Biotechnology written by Ulrich Kück and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mycology, the study of fungi, originated as a subdiscipline of botany and was a descriptive discipline, largely neglected as an experimental science until the early years of this century. A seminal paper by Blakeslee in 1904 provided evidence for self incompatibility, termed "heterothallism", and stimulated interest in studies related to the control of sexual reproduction in fungi by mating-type specificities. Soon to follow was the demonstration that sexually reproducing fungi exhibit Mendelian inheritance and that it was possible to conduct formal genetic analysis with fungi. The names Burgeff, Kniep and Lindegren are all associated with this early period of fungal genetics research. These studies and the discovery of penicillin by Fleming, who shared a Nobel Prize in 1945, provided further impetus for experimental research with fungi. Thus began a period of interest in mutation induction and analysis of mutants for bio chemical traits. Such fundamental research, conducted largely with Neurospora crassa, led to the one gene: one enzyme hypothesis and to a second Nobel Prize for fungal research awarded to Beadle and Tatum in 1958. Fundamental research in biochemical genetics was extended to other fungi, especially to Saccharomyces cere visiae, and by the mid-1960s fungal systems were much favored for studies in eukaryotic molecular biology and were soon able to compete with bacterial systems in the molecular arena.

Alfabeto de mamíferos

Author :
Publisher :
ISBN 13 :
Total Pages : 31 pages
Book Rating : 4.:/5 (433 download)

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Book Synopsis Alfabeto de mamíferos by :

Download or read book Alfabeto de mamíferos written by and published by . This book was released on 1881 with total page 31 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Photochemistry

Author : Angelo Albini
Publisher : Royal Society of Chemistry
ISBN 13 : 1788016521
Total Pages : 547 pages
Book Rating : 4.7/5 (88 download)

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Book Synopsis Photochemistry by : Angelo Albini

Download or read book Photochemistry written by Angelo Albini and published by Royal Society of Chemistry. This book was released on 2019-09-23 with total page 547 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drawing on the continued wealth of photochemical research, this volume combines reviews on the latest advances in the field with specific topical highlights. Starting with periodical reports of the recent literature on physical and inorganic aspects, light induced reactions in cryogenic matrices, properties of transition-metal compounds, time-resolved spectroscopy, the exploitation of solar energy and the molecules of colour. Coverage continues with highlighted topics, in the second part, from photoresponsive hydrogels, the tunable photoredox properties of organic dyes, light-driven asymmetric organocatalytic processes, dual gold–photoredox catalysis, the preparation and characterization of photosensitizers for triplet–triplet annihilation photon upconversion and the role of photochemistry on traditional synthetic processes. This volume will include for the first time a section entitled ‘SPR Lectures on Photochemistry’, providing examples for academic readers to introduce a photochemistry topic and precious help for students in photochemistry. Providing critical analysis of the topics, this book is essential reading for anyone wanting to keep up to date with the literature on photochemistry and its applications.

RNA Editing

Author : H. Ulrich Göringer
Publisher : Springer Science & Business Media
ISBN 13 : 3540737871
Total Pages : 239 pages
Book Rating : 4.5/5 (47 download)

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Book Synopsis RNA Editing by : H. Ulrich Göringer

Download or read book RNA Editing written by H. Ulrich Göringer and published by Springer Science & Business Media. This book was released on 2008-01-12 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: Goringer’s brilliant new work dedicates a chapter to each of the main types of RNA editing – the very first volume to do so. All of the sections here have been written by experts in the various research areas and a specific focus is put on the correlation between RNA structure and function, as well as on the complex cellular machineries that catalyze the different editing reactions. This leads to a "state of the art" compendium of our current knowledge on RNA editing.

Bioactive Ceramides in Health and Disease

Author : Johnny Stiban
Publisher : Springer Nature
ISBN 13 : 3030211622
Total Pages : 153 pages
Book Rating : 4.0/5 (32 download)

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Book Synopsis Bioactive Ceramides in Health and Disease by : Johnny Stiban

Download or read book Bioactive Ceramides in Health and Disease written by Johnny Stiban and published by Springer Nature. This book was released on 2019-09-09 with total page 153 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is about the various roles of bioactive ceramides and other sphingolipids in cellular biology. The enigmatic biophysical and biochemical properties of ceramides and their propensity to influence membranes whether as rafts or protein-permeable channels are heavily discussed. Metabolism of ceramides and their metabolites is also focused with ceramide synthase family of proteins being a target of extensive review. Ceramide 1-phosphate and other sphingolipids are also presented in cellular physiology and pathophysiology. Prokaryotic origins of mitochondria at the level of membranes and the occurrence of apoptosis in bacteria are presented. Many aspects of ceramide and sphingolipid biology are addressed in this book. Its focus is the metabolism of ceramide in normal and diseased states and the biophysical and biochemical mechanisms governing the bioactivity of these molecules. Sphingolipid research has surged over the past thirty years and this book gathers the recent findings of various aspects of sphingolipid biochemistry. World-renowned scientists from the field of lipid biology, specifically sphingolipid biochemistry, were gathered to write this book. Scholars from most continents of the globe committed to write diligently about their expertise and the newest findings in the relevant fields. This book came to fruition after almost a year and a half of laborious preparation and diligent writings. This book is targeted to the experienced reader who is looking to read about the various aspects of bioactive ceramide signaling, as well as to the newcomer into the field, as the topics are explained in concise yet very informative manner. The authors and editor wish all readers a pleasant time reading this volume, and are adamant that this book will meet all expectations.

Plant Mitochondria: From Genome to Function

Author : David Day
Publisher : Springer Science & Business Media
ISBN 13 : 9781402023996
Total Pages : 372 pages
Book Rating : 4.0/5 (239 download)

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Book Synopsis Plant Mitochondria: From Genome to Function by : David Day

Download or read book Plant Mitochondria: From Genome to Function written by David Day and published by Springer Science & Business Media. This book was released on 2004-08-27 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mitochondria in plants, as in other eukaryotes, play an essential role in the cell as the major producers of ATP via oxidative phosphorylation. However, mitochondria also play crucial roles in many other aspects of plant development and performance, and possess an array of unique properties which allow them to interact with the specialized features of plant cell metabolism. The two main themes running through the book are the interconnection between gene regulation and protein function, and the integration of mitochondria with other components of plant cells. The book begins with an overview of the dynamics of mitochondrial structure, morphology and inheritance. It then discusses the biogenesis of mitochondria, the regulation of gene expression, the mitochondrial genome and its interaction with the nucleus, and the targeting of proteins to the organelle. This is followed by a discussion of the contributions that mutations, involving mitochondrial proteins, have made to our understanding of the way the organelle interacts with the rest of the plant cell, and the new field of proteomics and the discovery of new functions. Also covered are the pathways of electron transport, with special attention to the non-phosphorylating bypasses, metabolite transport, and specialized mitochondrial metabolism. In the end, the impact of oxidative stress on mitochondria and the defense mechanisms, that are employed to allow survival, are discussed. This book is for the use of advanced undergraduates, graduates, postgraduates, and beginning researchers in the areas of molecular and cellular biology, integrative biology, biochemistry, bioenergetics, proteomics and plant and agricultural sciences.

Mitochondrial DNA and Diseases

Author : Hongzhi Sun
Publisher : Springer
ISBN 13 : 9811066744
Total Pages : 233 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis Mitochondrial DNA and Diseases by : Hongzhi Sun

Download or read book Mitochondrial DNA and Diseases written by Hongzhi Sun and published by Springer. This book was released on 2017-11-25 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book describes molecular principles and mechanisms by which mitochondrial DNA (mtDNA) can drive the occurrence of diseases and the latest understanding of mtDNA biology. The book explores roles of mtDNA mutation and genetic changes in cancer, with a special focus on lung cancer, and the significance of approach, application, and bioethics of mtDNA sequencing. Authors made a great effort to overview roles of mtDNA signaling pathways, base excision repair, methylation, USP30-mediated regulation, mitochondrial ribosome, autophagy pathways, or ROS-dependent signaling in the pathogenesis, diagnosis, prevention and treatment of diseases. It also demonstrates the importance of basic mitochondrial genetics and the relationship between mutations and disease phenotypes and ageing. This book covers not only the basic information of mtDNA, the relationship of mtDNA and disease, but also mtDNA in stem cell and mitochondria and metabolism etc. The book is written for biological and clinical students and researchers in the field of mtDNA–associated diseases.

Plant Mitochondria

Author : Olivier Van Aken
Publisher : Humana
ISBN 13 : 9781071616529
Total Pages : 342 pages
Book Rating : 4.6/5 (165 download)

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Book Synopsis Plant Mitochondria by : Olivier Van Aken

Download or read book Plant Mitochondria written by Olivier Van Aken and published by Humana. This book was released on 2021-10-15 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: This detailed volume presents a wide range of techniques for plant mitochondrial analysis, ranging from tried-and-tested work horse techniques to the latest innovations. Within its pages, it explores subjects such as affinity-based isolation of mitochondria with magnetic beads, mitochondrial quality assessment protocols, measurement of uptake and release of specific metabolites, mitochondrial protein identification and visualization, as well as gene splicing and editing, and much more. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Plant Mitochondria: Methods and Protocols provides a highly useful set of methodologies for the plant mitochondrial community to help discover more interesting aspects of plant mitochondria in the years to come.

Role of Mitochondria-Associated Non-Coding RNAs in Intracellular Communication

Author : Samarjit Das
Publisher : Frontiers Media SA
ISBN 13 : 2832501311
Total Pages : 128 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Role of Mitochondria-Associated Non-Coding RNAs in Intracellular Communication by : Samarjit Das

Download or read book Role of Mitochondria-Associated Non-Coding RNAs in Intracellular Communication written by Samarjit Das and published by Frontiers Media SA. This book was released on 2022-09-30 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: