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Risk Assessment For Neurobehavioral Toxicity
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Book Synopsis Risk Assessment for Neurobehavioral Toxicity by : Bernard Weiss
Download or read book Risk Assessment for Neurobehavioral Toxicity written by Bernard Weiss and published by DIANE Publishing. This book was released on 1997-07 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: After three decades of research, neurobehavioral toxicity is now acknowledged as a significant outcome of chemical exposure. Its health and economic costs may exceed those by cancer by substantial amounts. This new perspective has been accompanied by efforts designed to explore the responsible mechanisms, to design applicable risk assessment procedures, and to determine the consequent policy implications. This publication includes 25 papers from international experts and includes: human neurobehavioral toxicity; animal behavioral methods; selected model compounds; and risk assessment.
Author :Scientific Group on Methodologies for the Safety Evaluation of Chemicals. Workshop Publisher : ISBN 13 : Total Pages :266 pages Book Rating :4.3/5 ( download)
Book Synopsis Risk Assessment for Neurobehavioral Toxicity by : Scientific Group on Methodologies for the Safety Evaluation of Chemicals. Workshop
Download or read book Risk Assessment for Neurobehavioral Toxicity written by Scientific Group on Methodologies for the Safety Evaluation of Chemicals. Workshop and published by . This book was released on 1996 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Risk Assessment for Neurobehavioral Toxicity by : Bernard Weiss
Download or read book Risk Assessment for Neurobehavioral Toxicity written by Bernard Weiss and published by . This book was released on 1996 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :Scientific Group on Methodologies for the Safety Evaluation of Chemicals. Workshop Publisher : ISBN 13 : Total Pages :0 pages Book Rating :4.:/5 (134 download)
Book Synopsis Risk Assessment for Neurobehavioral Toxicity by : Scientific Group on Methodologies for the Safety Evaluation of Chemicals. Workshop
Download or read book Risk Assessment for Neurobehavioral Toxicity written by Scientific Group on Methodologies for the Safety Evaluation of Chemicals. Workshop and published by . This book was released on 1996 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Neurobehavioral Toxicity by : Bernard Weiss
Download or read book Neurobehavioral Toxicity written by Bernard Weiss and published by CRC Press. This book was released on 1994-06-30 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: In establishing how certain chemicals can cause behavioural disorders, the process of neurotoxicity risk assessment poses significant challenges to every discipline within neuroscience. In this volume, leaders from industrial, academic, and government settings share insights on behavioural measurement in neurotoxicity risk assessment, and address the critical scientific issues arising from the expanding role of neurobehavioral toxicology in public policy development.; The authors set out to provide a comprehensive and authoritative review of current methods in the analysis and interpretation of neurobehavioural toxicology. Coverage begins with a discussion of criteria for determining neurotoxic potential. The next section examines neurobehavioural evaluations in developmental neurotoxicity. Subsequent sections focus on activity and observational data and applications of schedule-controlled operant behaviour in toxicity testing. The contributors address controversies surrounding the suitability and interpretation of procedures designed for neurotoxicological assessments. Some case studies are also included.
Book Synopsis Behavioral Measures of Neurotoxicity by : National Research Council
Download or read book Behavioral Measures of Neurotoxicity written by National Research Council and published by National Academies Press. This book was released on 1990-02-01 with total page 449 pages. Available in PDF, EPUB and Kindle. Book excerpt: Exposure to toxic chemicalsâ€"in the workplace and at homeâ€"is increasing every day. Human behavior can be affected by such exposure and can give important clues that a person or population is in danger. If we can understand the mechanisms of these changes, we can develop better ways of testing for toxic chemical exposure and, most important, better prevention programs. This volume explores the emerging field of neurobehavioral toxicology and the potential of behavior studies as a noninvasive and economical means for risk assessment and monitoring. Pioneers in this field explore its promise for detecting environmental toxins, protecting us from exposure, and treating those who are exposed.
Book Synopsis Behavioral Toxicology by : Bernard Weiss
Download or read book Behavioral Toxicology written by Bernard Weiss and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 475 pages. Available in PDF, EPUB and Kindle. Book excerpt: Behavioral toxicology is a young discipline in the United States; so young, in fact, that this is one of its first books. Behavioral questions are bound to play a major role in future scientific work and governmental decisions involving the health effects of environmental contaminants and other chemicals. This role springs from two key problems that face scientists and public agencies required to set acceptable exposure standards or to determine criteria for the toxicity of therapeutic chemicals: How do you evaluate effects that may show up only as subtle functional disturbances? And how do you de tect toxic effects early enough so that they may still be reversible, before they produce major damage? The contributions in this book come from a collection of scientists whose interests span a wide variety of problem areas. The focus is largely on me thodological issues because they represent the most immediate concern of the discipline. We expect that this collection of papers will represent a useful source book for behavioral toxicology for some time. For the past few years, the University of Rochester's Department of Radiation Biology and Biophysics has sponsored a series of international conferences on chemical toxicity, partly as a response to concern over the con sequences to health of the rich chemical soup in which we live. This book is based upon presentations made to the fifth of the series. Held in June, 1972, it was the first formal meeting devoted to behavioral toxicology in this country.
Book Synopsis Neurobehavioral Toxicity Assessment by :
Download or read book Neurobehavioral Toxicity Assessment written by and published by . This book was released on 2007 with total page 20 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Environmental Neurotoxicology by : National Research Council
Download or read book Environmental Neurotoxicology written by National Research Council and published by National Academies Press. This book was released on 1992-02-01 with total page 167 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientists agree that exposure to toxic agents in the environment can cause neurological and psychiatric illnesses ranging from headaches and depression to syndromes resembling parkinsonism. It can even result in death at high exposure levels. The emergence of subclinical neurotoxicity-the concept that long-term impairments can escape clinical detection-makes the need for risk assessment even more critical. This volume paves the way toward definitive solutions, presenting the current consensus on risk assessment and environmental toxicants and offering specific recommendations. The book covers: The biologic basis of neurotoxicity. Progress in the application of biologic markers. Reviews of a wide range of in vitro and in vivo testing techniques. The use of surveillance and epidemiology to identify neurotoxic hazards that escape premarket screening. Research needs. This volume will be an important resource for policymakers, health specialists, researchers, and students.
Book Synopsis Science and Decisions by : National Research Council
Download or read book Science and Decisions written by National Research Council and published by National Academies Press. This book was released on 2009-03-24 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: Risk assessment has become a dominant public policy tool for making choices, based on limited resources, to protect public health and the environment. It has been instrumental to the mission of the U.S. Environmental Protection Agency (EPA) as well as other federal agencies in evaluating public health concerns, informing regulatory and technological decisions, prioritizing research needs and funding, and in developing approaches for cost-benefit analysis. However, risk assessment is at a crossroads. Despite advances in the field, risk assessment faces a number of significant challenges including lengthy delays in making complex decisions; lack of data leading to significant uncertainty in risk assessments; and many chemicals in the marketplace that have not been evaluated and emerging agents requiring assessment. Science and Decisions makes practical scientific and technical recommendations to address these challenges. This book is a complement to the widely used 1983 National Academies book, Risk Assessment in the Federal Government (also known as the Red Book). The earlier book established a framework for the concepts and conduct of risk assessment that has been adopted by numerous expert committees, regulatory agencies, and public health institutions. The new book embeds these concepts within a broader framework for risk-based decision-making. Together, these are essential references for those working in the regulatory and public health fields.
Book Synopsis Guidelines for Neurotoxicity Risk Assessment by :
Download or read book Guidelines for Neurotoxicity Risk Assessment written by and published by . This book was released on 1998 with total page 90 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Regulation for Chemical Safety in Europe: Analysis, Comment and Criticism by : D.M. Pugh
Download or read book Regulation for Chemical Safety in Europe: Analysis, Comment and Criticism written by D.M. Pugh and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many European Union Directives seek to minimize the potential for harm to humans and the environment arising from the use of chemicals. This book takes an interdisciplinary, selective look at the effector mechanisms employed in such directives. It covers the pre-marketing use of toxicology to identify the hazardous properties of chemicals, acknowledging its shortcomings, while contrasting the scientific method with the precautionary principle in developing risk-management practices. The book then goes on to describe the use of bio-indicators, chemical analyses and mathematical modelling for prediction, or to determine the adequacy of chemical safety legislation. The environmental risk assessment of priority chemicals is described and the impact of pesticides on sustainability in agriculture is discussed from the differing standpoints of agronomy and economics. Audience: All professionals concerned with the safe management of chemicals and their use, including teachers, practitioners, policy makers or legislators.
Book Synopsis Environmental Health Perspectives by :
Download or read book Environmental Health Perspectives written by and published by . This book was released on 1993 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Toxicological Effects of Methylmercury by : National Research Council
Download or read book Toxicological Effects of Methylmercury written by National Research Council and published by National Academies Press. This book was released on 2000-09-27 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mercury is widespread in our environment. Methylmercury, one organic form of mercury, can accumulate up the aquatic food chain and lead to high concentrations in predatory fish. When consumed by humans, contaminated fish represent a public health risk. Combustion processes, especially coal-fired power plants, are major sources of mercury contamination in the environment. The U.S. Environmental Protection Agency (EPA) is considering regulating mercury emissions from those plants. Toxicological Effects of Methylmercury reviews the health effects of methylmercury and discusses the estimation of mercury exposure from measured biomarkers, how differences between individuals affect mercury toxicity, and appropriate statistical methods for analysis of the data and thoroughly compares the epidemiological studies available on methylmercury. Included are discussions of current mercury levels on public health and a delineation of the scientific aspects and policy decisions involved in the regulation of mercury. This report is a valuable resource for individuals interested in the public health effects and regulation of mercury. The report also provides an excellent example of the implications of decisions in the risk assessment process for a larger audience.
Book Synopsis Handbook of Developmental Neurotoxicology by : William Slikker Jr.
Download or read book Handbook of Developmental Neurotoxicology written by William Slikker Jr. and published by Academic Press. This book was released on 2018-01-04 with total page 618 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Developmental Neurotoxicology, Second Edition, provides a comprehensive view of the fundamental aspects of neurodevelopment, the pathways and agents that affect them, relevant clinical syndromes, and risk assessment procedures for developmental neurotoxicants. The editors and chapter authors are internationally recognized experts whose collaboration heralds a remarkable advance in the field, bridging developmental neuroscience with the principles of neurotoxicology. The book features eight new chapters with newly recruited authors, making it an essential text for students and professionals in toxicology, neurotoxicology, developmental biology, pharmacology, and neuroscience. Presents a comprehensive, up-to-date resource on developmental neurotoxicology with updated chapters from the first edition Contains new chapters that focus on subjects recent to the field Includes well-illustrated material, with diagrams, charts, and tables Contains compelling case studies and chapters written by world experts
Book Synopsis A Comprehensive Guide to Toxicology in Preclinical Drug Development by : Ali S. Faqi
Download or read book A Comprehensive Guide to Toxicology in Preclinical Drug Development written by Ali S. Faqi and published by Academic Press. This book was released on 2012-11-02 with total page 904 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Comprehensive Guide to Toxicology in Preclinical Drug Development is designed for toxicologists who need a thorough understanding of the drug development process. This multi-contributed reference will provide a detailed picture of the complex and highly interrelated activities of preclinical toxicology in both small molecules and biologics --
Book Synopsis Human Variability in Response to Chemical Exposures Measures, Modeling, and Risk Assessment by : David A. Eckerman
Download or read book Human Variability in Response to Chemical Exposures Measures, Modeling, and Risk Assessment written by David A. Eckerman and published by CRC Press. This book was released on 1998-08-25 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: and for those interested in toxic effects of chemicals on humans, Human Variability in Response to Chemical Exposures: Measures, Modeling, and Risk Assessment recognizes and addresses the increasing awareness that individual biological differences be reflected when assessing human health risks associated with exposure to chemicals. Eight original manuscripts, commissioned by the ILSI Risk Science Institute, address the evidence for variability in human response to chemicals associated with reproductive and developmental effects, effects on the nervous system and lungs, and cancer. Their reports convey both the current state of scientific understanding of response variability and the genetic basis for such observations. This book recognizes that understanding of variability in response is critical in accounting for interindividual variability in susceptibility and, hence, risk, if the regulatory community and others are expected to characterize human health risks associated with exposure to chemicals. Models for incorporating measures of response variability in the risk assessment process are critically reviewed and illustrated with published data. This authoritative work indicates that, in the case of certain chemicals and in the context of certain specific toxic effects, we have considerable ability to predictively and quantitatively characterize human variability, but, in the majority of cases, our ability to do so is limited. If we improve both quantity and quality of information available on response variability and increase our understanding of target tissue dosimetry, we should be better able to account for variability in human susceptibility to the toxic effects of chemicals.
