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Revisiting The Thymus The Origin Of T Cells
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Book Synopsis Revisiting the thymus: The origin of T cells by : Yayi Gao
Download or read book Revisiting the thymus: The origin of T cells written by Yayi Gao and published by Frontiers Media SA. This book was released on 2023-05-04 with total page 137 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Fish Immune System: Organism, Pathogen, and Environment by :
Download or read book The Fish Immune System: Organism, Pathogen, and Environment written by and published by Academic Press. This book was released on 1997-02-20 with total page 395 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book comprehensively reviews the immunology of fish--their health, interactions between them and their pathogens, and the impact of both endogenous and environmental changes on these interactions. Leading authorities provide an essential foundation for the understanding of fish immunology and fish health.As fish are increasingly used as model systems for vertebrate immune systems, The Fish Immune System will be a crucial reference. - The only comprehensive, single-volume reference on the fish immune system - Contributions from an international team of experts - Useful to researchers interested in fish health as well as professionals managing fish hatcheries, aquariums, and other facilities that must maintain healthy fish
Book Synopsis CD4+CD25+ Regulatory T Cells: Origin, Function and Therapeutic Potential by : B. Kyewski
Download or read book CD4+CD25+ Regulatory T Cells: Origin, Function and Therapeutic Potential written by B. Kyewski and published by Springer Science & Business Media. This book was released on 2006-01-09 with total page 331 pages. Available in PDF, EPUB and Kindle. Book excerpt: The vertebrate immune system defends the organism against invading pathogens while at the same time being self-tolerant to the body’s own constituents thus preserving its integrity. Multiple mechanisms work in concert to ensure self-tolerance. Apart from purging the T cell repertoire from auto-reactive T cells via negative selection in the thymus dominant tolerance exerted by regulatory T cells plays a major role in tolerance imposition and maintenance. Among the various regulatory/suppressive cells hitherto described, CD4+CD25+ regulatory T cells (Treg) and interleukin-10 producing T regulatory 1 (Tr1) cells have been studied in most detail and are the subject of most articles in this issue. Treg, also called "natural" regulatory T cells, will be traced from their intra-thymic origin to the site of their action in peripheral lymphoid organs and tissues. The repertoire of Treg is clearly biased towards recognition of self-antigens, thereby potentially preventing autoimmune diseases such as gastritis and oophoritis. Regulatory T cells, however also control infections, allergies and tolerance to transplanted tissues and this requires their induction in the periphery under conditions which are not yet fully understood. The concept of dominant tolerance, by far not novel, will offer new insights and hopefully tools for the successful treatment of autoimmune diseases, improved cancer immunotherapy and transplant survival. The fulfillment of these high expectations will, however, require their unambiguous identification and a better understanding of their mode of action.
Book Synopsis A Living History of Immunology by : Kendall Arthur Smith
Download or read book A Living History of Immunology written by Kendall Arthur Smith and published by Frontiers Media SA. This book was released on 2015-11-04 with total page 64 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the highly competitive world of biomedical science, often the rush to publish and to be recognized as "first" with a new discovery, concept or method, is lost in the hurly-burly of the moment, as "the maddening crowd" moves on to the next "new thing". One of the great things about immunology today is that it has only become mature as a science within the last half-century, and especially within the past 35 years as a consequence of the revolution of molecular immunology, which has taken place only since 1980. Consequently, most of those who have contributed to our new understanding of how the immune system functions are still alive and well, and still contributing. Thus, "A Living History of Immunology" collates many stories from the investigators who actually performed the experiments that have established the frontiers of immunology. Accordingly, this volume combats "revisionist science", by those who want to alter history by telling the stories a different way than actually happened. In this regard, one of the good things about science vs. other disciplines is that we have the written record of what was done, when it was done and by whom. Even so, we do not have the complete story or narrative of how and why experiments were done, and what made the differences that led to success. This volume captures and chronicles some of these stories from the past fifty years in immunology.
Book Synopsis Fetal/Embryonic Hematopoietic Progenitors and Their Impact on Adult Diseases by : Silvia Brunelli
Download or read book Fetal/Embryonic Hematopoietic Progenitors and Their Impact on Adult Diseases written by Silvia Brunelli and published by Frontiers Media SA. This book was released on 2021-10-01 with total page 175 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :Siddhartha Mukherjee Publisher :Penguin Random House India Private Limited ISBN 13 :9354927580 Total Pages :552 pages Book Rating :4.3/5 (549 download)
Book Synopsis The Song of the Cell by : Siddhartha Mukherjee
Download or read book The Song of the Cell written by Siddhartha Mukherjee and published by Penguin Random House India Private Limited. This book was released on 2022-10-30 with total page 552 pages. Available in PDF, EPUB and Kindle. Book excerpt: From Pulitzer Prize-winning and #1 New York Times bestselling author of The Emperor of All Maladies and The Gene, The Song of The Cell is the third book in this extraordinary writer's exploration of what it means to be human-rich with Siddhartha Mukherjee's revelatory and exhilarating stories of scientists, doctors, and all the patients whose lives may be saved by their work. In the late 1600s, a distinguished English polymath, Robert Hooke, and an eccentric Dutch cloth merchant, Antonie van Leeuwenhoek, look down their handmade microscopes. What they see introduces a radical concept that sweeps through biology and medicine, touching virtually every aspect of the two sciences and altering both forever. It is the fact that complex living organisms are assemblages of tiny, self-contained, self-regulating units. Our organs, our physiology, our selves-hearts, blood, brains-are built from these compartments. Hooke christens them 'cells'. The discovery of cells-and the reframing of the human body as a cellular ecosystem-announced the birth of a new kind of medicine based on the therapeutic manipulations of cells. A hip fracture, a cardiac arrest, Alzheimer's, dementia, AIDS, pneumonia, lung cancer, kidney failure, arthritis, COVID-all could be viewed as the results of cells, or systems of cells, functioning abnormally. And all could be perceived as loci of cellular therapies. In The Song of the Cell, Mukherjee tells the story of how scientists discovered cells, began to understand them, and are now using that knowledge to create new humans. He seduces readers with writing so vivid, lucid, and suspenseful that complex science becomes thrilling. Told in six parts, laced with Mukherjee's own experience as a researcher, doctor, and prolific reader, The Song of the Cell is both panoramic and intimate-a masterpiece.
Book Synopsis Revisiting Behavioral Variability: What It Reveals About Neural Circuit Structure and Function by : Kenta Asahina
Download or read book Revisiting Behavioral Variability: What It Reveals About Neural Circuit Structure and Function written by Kenta Asahina and published by Frontiers Media SA. This book was released on 2022-08-23 with total page 162 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Regulatory T Cells in Inflammation by : Leonie S. Taams
Download or read book Regulatory T Cells in Inflammation written by Leonie S. Taams and published by Springer Science & Business Media. This book was released on 2006-03-30 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: Regulatory T-cells are essential components of the immune system, and several different subsets of regulatory T-cells have been described. Considerable regulatory function has been attributed to the CD4+CD25+ T-cell subset. These cells act by suppressing adaptive and possibly innate immune responses thereby maintaining or restoring the balance between immunity and tolerance. The suppressive effects of CD4+CD25+ regulatory T-cells are cell-contact dependent. Recent developments and viewpoints in the field of CD4+CD25+ regulatory T-cells as well as the potential use of regulatory T-cells in immunotherapy of inflammatory diseases are discussed in this volume. By linking data from experimental models with recent findings from the clinic, this book will be of interest to immunologists and other biomedical researchers as well as clinicians interested in the regulation and manipulation of the immune response during inflammatory disease.
Author :Leandro Nunes de Castro Publisher :Springer Science & Business Media ISBN 13 :1852335947 Total Pages :380 pages Book Rating :4.8/5 (523 download)
Book Synopsis Artificial Immune Systems: A New Computational Intelligence Approach by : Leandro Nunes de Castro
Download or read book Artificial Immune Systems: A New Computational Intelligence Approach written by Leandro Nunes de Castro and published by Springer Science & Business Media. This book was released on 2002-09-23 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: Artificial Immune Systems (AIS) are adaptive systems inspired by the biological immune system and applied to problem solving. This book provides an accessible introduction that will be suitable for anyone who is beginning to study or work in this area. It gives a clear definition of an AIS, sets out the foundations of the topic (including basic algorithms), and analyses how the immune system relates to other biological systems and processes. No prior knowledge of immunology is needed - all the essential background information is covered in the introductory chapters. Key features of the book include: - A discussion of AIS in the context of Computational Intelligence; - Case studies in Autonomous Navigation, Computer Network Security, Job-Shop Scheduling and Data Analysis =B7 An extensive survey of applications; - A framework to help the reader design and understand AIS; - A web site with additional resources including pseudocodes for immune algorithms, and links to related sites. Written primarily for final year undergraduate and postgraduate students studying Artificial Intelligence, Evolutionary and Biologically Inspired Computing, this book will also be of interest to industrial and academic researchers working in related areas.
Book Synopsis Regulatory T Cells in Health and Disease by :
Download or read book Regulatory T Cells in Health and Disease written by and published by Academic Press. This book was released on 2015-11-26 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt: Regulatory T Cells in Health and Disease focuses on the mechanism by which T cells become regulatory T cells, the processes which control the number of regulatory T cells in the blood and tissue, and the ways in which regulatory T cell prevent autoimmune disease and interact with infections and cancer. - Contains contributions from leading authorities in the field of regulatory T cell biology - Informs and updates on all the latest developments in the field - Explores the processes which control the number of regulatory T cells in the blood and tissue, and the ways in which regulatory T cell prevent autoimmune disease and interact with infections and cancer
Book Synopsis Stiehm's Immune Deficiencies by : Kathleen E. Sullivan
Download or read book Stiehm's Immune Deficiencies written by Kathleen E. Sullivan and published by Academic Press. This book was released on 2020-05-23 with total page 1334 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stiehm's Immune Deficiencies: Inborn Errors in Immunity, Second Edition, is ideal for physicians and other caregivers who specialize in immunology, allergies, infectious diseases and pulmonary medicine. It provides a validated source of information for care delivery to patients, covering approaches to diagnosis that use both new genetic information and emphasize screening strategies. Management has changed dramatically over the past five years, so approaches to infection and autoimmunity are emphasized in an effort to improve outcomes and disseminate new information on the uses of targeted therapy. - Covers immune deficiencies that are presented in a practical way, providing helpful information for active clinicians - Fills an increasingly deep gap in the information available to clinicians - Presents both clinical management and scientific advances for immune deficiencies - Provides a primary resource for physicians in the field of immunodeficiencies - Includes website access to a range of videos relevant to the topics discussed
Book Synopsis Translational Immunotherapy of Brain Tumors by : John H. Sampson
Download or read book Translational Immunotherapy of Brain Tumors written by John H. Sampson and published by Academic Press. This book was released on 2017-02-06 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: Translational Immunotherapy of Brain Tumors gives researchers and practitioners an up-to-date and comprehensive overview of the field. Chapters include adoptive immunotherapy, immunosuppression, CAR therapy of brain tumors, and dendritic cell therapy for brain tumors. Very few agents have been shown to be efficacious in the treatment of malignant gliomas. Recently, there have been a number of studies demonstrating the potential success of immunotherapy for brain tumors. Immunotherapeutics are becoming the most frequent drugs to be used in cancer therapy. These new breakthroughs, now approved by the FDA, are a part of multiple phase III international trials and ongoing research in malignant glioma, meaning that the information in this cutting-edge book will be of great importance to practitioners and researchers alike. 2018 BMA Medical Book Awards Highly Commended in Oncology - Comprehensive overview, providing an update on immunology, translational immunotherapy, and clinical trials relating to malignant gliomas - Edited by a prominent neurosurgeon with contributions by leading researchers in the field - Ideal resource for researchers and practitioners interested in learning about mechanisms that use the immune system to treat brain tumors
Book Synopsis The Gut Microbiome in Health and Disease by : Dirk Haller
Download or read book The Gut Microbiome in Health and Disease written by Dirk Haller and published by Springer. This book was released on 2018-07-27 with total page 355 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book provides an overview on how the gut microbiome contributes to human health. The readers will get profound knowledge on the connection between intestinal microbiota and immune defense systems. The tools of choice to study the ecology of these highly-specialized microorganism communities such as high-throughput sequencing and metagenomic mining will be presented. In addition the most common diseases associated to the composition of the gut flora are discussed in detail. The book will address researchers, clinicians and advanced students working in biomedicine, microbiology and immunology.
Book Synopsis Immunology for Surgeons by : Andrew P. Zbar
Download or read book Immunology for Surgeons written by Andrew P. Zbar and published by Springer Science & Business Media. This book was released on 2002-02-20 with total page 486 pages. Available in PDF, EPUB and Kindle. Book excerpt: An understanding of the complex workings of the immune system is essential for all surgeons. Immune responses play a crucial part in the way human body reacts to infection and trauma. Immunology for Surgeons contains a high-level discussion of this difficult clinical area. The text looks at tumor immunobiology and immunotherapy as well as the worldwide results of various clinical trials. The topics discussed focus on relevant immunological and molecular biological trends for future treatment of complex surgical disease. The main objective of the text is to render a difficult area accessible for the postgraduate surgical trainee and established surgeon who is interested in immunology.
Book Synopsis Diagnosis of Blood and Bone Marrow Disorders by : Sa A. Wang
Download or read book Diagnosis of Blood and Bone Marrow Disorders written by Sa A. Wang and published by Springer. This book was released on 2018-06-04 with total page 413 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on hematopoietic and lymphoid neoplasms that initially present as peripheral blood abnormalities, with either cytopenias or elevated peripheral blood counts, as well as non-neoplastic conditions that may raise concern for a hematologic malignancy. The scope of the book includes myelodysplastic syndromes (MDS), myeloproliferative neoplasms (MPN), mixed myelodysplastic/myeloproliferative neoplasms (MDS/MPN), as well as lymphomas and lymphoid leukemias that typically present initially with peripheral blood abnormalities. Within each category, a comprehensive list of differential diagnoses is discussed. For each disease entity, the reader is updated with new molecular genetic data, biomarkers, and recent applications of immunophenotyping, and how to incorporate the new information in disease diagnosis and classifications is illustrated, including the use of diagnostic algorithms where appropriate. The book employs the revised WHO Classification of Hematopoietic Neoplasms for all disease entities. Diagnosis of Blood and Bone Marrow Disorders will serve as a very useful resource for pathologists, pathologists in training, hematologists and medical technologists who are involved in the clinical work-up of patients with bone marrow and blood neoplasms. It will provide a practical and concise yet comprehensive review.
Book Synopsis Essential Immunology by : Ivan Maurice Roitt
Download or read book Essential Immunology written by Ivan Maurice Roitt and published by . This book was released on 1971 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Philosophy of Immunology by : Thomas Pradeu
Download or read book Philosophy of Immunology written by Thomas Pradeu and published by Cambridge University Press. This book was released on 2020-02-13 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Immunology is central to contemporary biology and medicine, but it also provides novel philosophical insights. Its most significant contribution to philosophy concerns the understanding of biological individuality: what a biological individual is, what makes it unique, how its boundaries are established and what ensures its identity through time. Immunology also offers answers to some of the most interesting philosophical questions. What is the definition of life? How are bodily systems delineated? How do the mind and the body interact? In this Element, Thomas Pradeu considers the ways in which immunology can shed light on these and other important philosophical issues. This title is also available as Open Access on Cambridge Core.