Review of the Federal Strategy for Nanotechnology-Related Environmental, Health, and Safety Research

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Author :
Publisher : National Academies Press
ISBN 13 : 0309185831
Total Pages : 131 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Review of the Federal Strategy for Nanotechnology-Related Environmental, Health, and Safety Research by : National Research Council

Download or read book Review of the Federal Strategy for Nanotechnology-Related Environmental, Health, and Safety Research written by National Research Council and published by National Academies Press. This book was released on 2009-02-17 with total page 131 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new book from the National Research Council finds serious weaknesses in the government's plan for research on the potential health and environmental risks posed by nanomaterials, which are increasingly being used in consumer goods and industry. An effective national plan for identifying and managing potential risks is essential to the successful development and public acceptance of nanotechnology-enabled products. The book recommends a robust national strategic plan for addressing nanotechnology-related EHS risks, which will need to focus on promoting research that can assist all stakeholders, including federal agencies, in planning, controlling, and optimizing the use of engineered nanomaterials while minimizing EHS effects of concern to society. Such a plan will ensure the timely development of engineered nanoscale materials that will bring about great improvements in the nation's health, its environmental quality, its economy, and its security.

Review of Federal Strategy for Nanotechnology-Related Environmental, Health, and Safety Research

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Author :
Publisher :
ISBN 13 : 9780309384209
Total Pages : 130 pages
Book Rating : 4.3/5 (842 download)

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Book Synopsis Review of Federal Strategy for Nanotechnology-Related Environmental, Health, and Safety Research by : Committee for Review of the Federal Strategy to Address Environmental Health and Safety Research Needs for Engineered Nanoscale Materials

Download or read book Review of Federal Strategy for Nanotechnology-Related Environmental, Health, and Safety Research written by Committee for Review of the Federal Strategy to Address Environmental Health and Safety Research Needs for Engineered Nanoscale Materials and published by . This book was released on 2009-02-17 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new book from the National Research Council finds serious weaknesses in the government's plan for research on the potential health and environmental risks posed by nanomaterials, which are increasingly being used in consumer goods and industry. An effective national plan for identifying and managing potential risks is essential to the successful development and public acceptance of nanotechnology-enabled products. The book recommends a robust national strategic plan for addressing nanotechnology-related EHS risks, which will need to focus on promoting research that can assist all stakeholders, including federal agencies, in planning, controlling, and optimizing the use of engineered nanomaterials while minimizing EHS effects of concern to society. Such a plan will ensure the timely development of engineered nanoscale materials that will bring about great improvements in the nation's health, its environmental quality, its economy, and its security.

A Research Strategy for Environmental, Health, and Safety Aspects of Engineered Nanomaterials

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Author :
Publisher : National Academies Press
ISBN 13 : 0309253314
Total Pages : 230 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis A Research Strategy for Environmental, Health, and Safety Aspects of Engineered Nanomaterials by : National Research Council

Download or read book A Research Strategy for Environmental, Health, and Safety Aspects of Engineered Nanomaterials written by National Research Council and published by National Academies Press. This book was released on 2012-05-09 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: The nanotechnology sector, which generated about $225 billion in product sales in 2009, is predicted to expand rapidly over the next decade with the development of new technologies that have new capabilities. The increasing production and use of engineered nanomaterials (ENMs) may lead to greater exposures of workers, consumers, and the environment, and the unique scale-specific and novel properties of the materials raise questions about their potential effects on human health and the environment. Over the last decade, government agencies, academic institutions, industry, and others have conducted many assessments of the environmental, health, and safety (EHS) aspects of nanotechnology. The results of those efforts have helped to direct research on the EHS aspects of ENMs. However, despite the progress in assessing research needs and despite the research that has been funded and conducted, developers, regulators, and consumers of nanotechnology-enabled products remain uncertain about the types and quantities of nanomaterials in commerce or in development, their possible applications, and their associated risks. A Research Strategy for Environmental, Health, and Safety Aspects of Engineered Nanomaterials presents a strategic approach for developing the science and research infrastructure needed to address uncertainties regarding the potential EHS risks of ENMs. The report summarizes the current state of the science and high-priority data gaps on the potential EHS risks posed by ENMs and describes the fundamental tools and approaches needed to pursue an EHS risk research strategy. The report also presents a proposed research agenda, short-term and long-term research priorities, and estimates of needed resources and concludes by focusing on implementation of the research strategy and evaluation of its progress, elements that the committee considered integral to its charge.

A Research Strategy for Environmental, Health, and Safety Aspects of Engineered Nanomaterials

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Author :
Publisher : National Academies Press
ISBN 13 : 0309253284
Total Pages : 230 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis A Research Strategy for Environmental, Health, and Safety Aspects of Engineered Nanomaterials by : National Research Council

Download or read book A Research Strategy for Environmental, Health, and Safety Aspects of Engineered Nanomaterials written by National Research Council and published by National Academies Press. This book was released on 2012-06-09 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: The nanotechnology sector, which generated about $225 billion in product sales in 2009, is predicted to expand rapidly over the next decade with the development of new technologies that have new capabilities. The increasing production and use of engineered nanomaterials (ENMs) may lead to greater exposures of workers, consumers, and the environment, and the unique scale-specific and novel properties of the materials raise questions about their potential effects on human health and the environment. Over the last decade, government agencies, academic institutions, industry, and others have conducted many assessments of the environmental, health, and safety (EHS) aspects of nanotechnology. The results of those efforts have helped to direct research on the EHS aspects of ENMs. However, despite the progress in assessing research needs and despite the research that has been funded and conducted, developers, regulators, and consumers of nanotechnology-enabled products remain uncertain about the types and quantities of nanomaterials in commerce or in development, their possible applications, and their associated risks. A Research Strategy for Environmental, Health, and Safety Aspects of Engineered Nanomaterials presents a strategic approach for developing the science and research infrastructure needed to address uncertainties regarding the potential EHS risks of ENMs. The report summarizes the current state of the science and high-priority data gaps on the potential EHS risks posed by ENMs and describes the fundamental tools and approaches needed to pursue an EHS risk research strategy. The report also presents a proposed research agenda, short-term and long-term research priorities, and estimates of needed resources and concludes by focusing on implementation of the research strategy and evaluation of its progress, elements that the committee considered integral to its charge.

Nanotechnology: Accuracy of Data on Federally Funded Environmental, Health, and Safety Research Could Be Improved

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Author :
Publisher : DIANE Publishing
ISBN 13 : 1437904351
Total Pages : 18 pages
Book Rating : 4.4/5 (379 download)

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Book Synopsis Nanotechnology: Accuracy of Data on Federally Funded Environmental, Health, and Safety Research Could Be Improved by : Robert A. Robinson

Download or read book Nanotechnology: Accuracy of Data on Federally Funded Environmental, Health, and Safety Research Could Be Improved written by Robert A. Robinson and published by DIANE Publishing. This book was released on 2009 with total page 18 pages. Available in PDF, EPUB and Kindle. Book excerpt: In March 2008, a report was issued which reviewed the Nat. Nanotechnology Initiative (NNI), a multi-agency effort. The NNI coordinates the nanotechnology-related activities of 25 federal agencies that fund nano-scale research or have a stake in the results. A key research area related to studying the potential environmental, health, and safety (EHS) risks that may result from exposure to nano-scale materials. Here is a summary of the findings of the 3/08 report, focusing on: (1) the extent to which selected agencies conducted EHS research in FY2006; (2) the reasonableness of the agencies¿ and the NNI¿s processes to identify and prioritize EHS research; and (3) the effectiveness of the agencies¿ and the NNI¿s process to coordinate EHS research.

Nanotechnology and Environmental Health and Safety: Issues for Consideration

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Author :
Publisher : DIANE Publishing
ISBN 13 : 1437982484
Total Pages : 41 pages
Book Rating : 4.4/5 (379 download)

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Book Synopsis Nanotechnology and Environmental Health and Safety: Issues for Consideration by : John F. Sargent

Download or read book Nanotechnology and Environmental Health and Safety: Issues for Consideration written by John F. Sargent and published by DIANE Publishing. This book was released on 2008 with total page 41 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanotechnology a term encompassing nanoscale science, engineering, and technology is focused on understanding, controlling, and exploiting the unique properties of matter that can emerge at scales of one to 100 nanometers. A key issue before Congress regarding nanotechnology is how best to protect human health, safety, and the environment as nanoscale materials and products are researched, developed, manufactured, used, and discarded. While the rapidly emerging field of nanotechnology is believed by many to offer significant economic and societal benefits, some research results have raised concerns about the potential adverse environmental, health, and safety (EHS) implications of nanoscale materials. Stakeholders generally agree that concerns about potential detrimental effects of nanoscale materials and devices both real and perceived must be addressed to protect and improve human health, safety, and the environment; enable accurate and efficient risk assessment, risk management, and cost-benefit trade-offs; foster innovation and public confidence; and ensure that society can enjoy the widespread economic and societal benefits that nanotechnology may offer. Congressionally-mandated reviews of the National Nanotechnology Initiative (NNI) by the National Research Council and the President's Council of Advisors on Science and Technology have concluded that additional research is required to make a rigorous risk assessment of nanoscale materials.

Research Progress on Environmental, Health, and Safety Aspects of Engineered Nanomaterials

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Author :
Publisher : National Academies Press
ISBN 13 : 0309291895
Total Pages : 163 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis Research Progress on Environmental, Health, and Safety Aspects of Engineered Nanomaterials by : National Research Council

Download or read book Research Progress on Environmental, Health, and Safety Aspects of Engineered Nanomaterials written by National Research Council and published by National Academies Press. This book was released on 2013-11-25 with total page 163 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite the increase in funding for research and the rising numbers of peer-reviewed publications over the past decade that address the environmental, health, and safety aspects of engineered nanomaterials (ENMs), uncertainty about the implications of potential exposures of consumers, workers, and ecosystems to these materials persists. Consumers and workers want to know which of these materials they are exposed to and whether the materials can harm them. Industry is concerned about being able to predict with sufficient certainty whether products that it makes and markets will pose any environmental, health or safety issues and what measures should be taken regarding manufacturing practices and worldwide distribution to minimize any potential risk. However, there remains a disconnect between the research that is being carried out and its relevance to and use by decision-makers and regulators to make informed public health and environmental policy and regulatory decisions. Research Progress on Environmental, Health, and Safety Aspects of Nanomaterials evaluates research progress and updates research priorities and resource estimates on the basis of results of studies and emerging trends in the nanotechnology industry. This report follows up the 2012 report A Research Strategy for Environmental, Health, and Safety Aspects of Engineered Nanomaterials, which presented a strategic approach for developing the science and research infrastructure needed to address uncertainties regarding the potential environmental, health, and safety risks posed by ENMs. This new report looks at the state of nanotechnology research, examines market and regulatory conditions and their affect on research priorities, and considers the criteria for evaluating research progress on the environmental, health, and safety aspects of nanotechnology.

Triennial Review of the National Nanotechnology Initiative

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Author :
Publisher : National Academies Press
ISBN 13 : 0309269334
Total Pages : 186 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis Triennial Review of the National Nanotechnology Initiative by : National Research Council

Download or read book Triennial Review of the National Nanotechnology Initiative written by National Research Council and published by National Academies Press. This book was released on 2013-12-20 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: The National Nanotechnology Initiative (NNI) is a multiagency, multidisciplinary federal initiative comprising a collection of research programs and other activities funded by the participating agencies and linked by the vision of "a future in which the ability to understand and control matter at the nanoscale leads to a revolution in technology and industry that benefits society." As first stated in the 2004 NNI strategic plan, the participating agencies intend to make progress in realizing that vision by working toward four goals. Planning, coordination, and management of the NNI are carried out by the interagency Nanoscale Science, Engineering, and Technology (NSET) Subcommittee of the National Science and Technology Council (NSTC) Committee on Technology (CoT) with support from the National Nanotechnology Coordination Office (NNCO). Triennial Review of the National Nanotechnology Initiative is the latest National Research Council review of the NNI, an assessment called for by the 21st Century Nanotechnology Research and Development Act of 2003. The overall objective of the review is to make recommendations to the NSET Subcommittee and the NNCO that will improve the NNI's value for basic and applied research and for development of applications in nanotechnology that will provide economic, societal, and national security benefits to the United States. In its assessment, the committee found it important to understand in some detail-and to describe in its report-the NNI's structure and organization; how the NNI fits within the larger federal research enterprise, as well as how it can and should be organized for management purposes; and the initiative's various stakeholders and their roles with respect to research. Because technology transfer, one of the four NNI goals, is dependent on management and coordination, the committee chose to address the topic of technology transfer last, following its discussion of definitions of success and metrics for assessing progress toward achieving the four goals and management and coordination. Addressing its tasks in this order would, the committee hoped, better reflect the logic of its approach to review of the NNI. Triennial Review of the National Nanotechnology Initiative also provides concluding remarks in the last chapter.

Triennial Review of the National Nanotechnology Initiative

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Author :
Publisher : National Academies Press
ISBN 13 : 0309447976
Total Pages : 149 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Triennial Review of the National Nanotechnology Initiative by : National Academies of Sciences, Engineering, and Medicine

Download or read book Triennial Review of the National Nanotechnology Initiative written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2016-12-12 with total page 149 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanoscale science, engineering, and technology, often referred to simply as "nanotechnology," is the understanding, characterization, and control of matter at the scale of nanometers, the dimension of atoms and molecules. Advances in nanotechnology promise new materials and structures that are the basis of solutions, for example, for improving human health, optimizing available energy and water resources, supporting a vibrant economy, raising the standard of living, and increasing national security. Established in 2001, the National Nanotechnology Initiative (NNI) is a coordinated, multiagency effort with the mission to expedite the discovery, development, and deployment of nanoscale science and technology to serve the public good. This report is the latest triennial review of the NNI called for by the 21st Century Nanotechnology Research and Development Act of 2003. It examines and comments on the mechanisms in use by the NNI to advance focused areas of nanotechnology towards advanced development and commercialization and on the physical and human infrastructure needs for successful realization in the United States of the benefits of nanotechnology development.

Research on Environmental and Safety Impacts of Nanotechnology

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Author :
Publisher :
ISBN 13 :
Total Pages : 196 pages
Book Rating : 4.0/5 ( download)

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Book Synopsis Research on Environmental and Safety Impacts of Nanotechnology by : United States. Congress. House. Committee on Science

Download or read book Research on Environmental and Safety Impacts of Nanotechnology written by United States. Congress. House. Committee on Science and published by . This book was released on 2006 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Triennial Review of the National Nanotechnology Initiative

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Author :
Publisher : National Academies Press
ISBN 13 : 0309269229
Total Pages : 187 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis Triennial Review of the National Nanotechnology Initiative by : National Research Council

Download or read book Triennial Review of the National Nanotechnology Initiative written by National Research Council and published by National Academies Press. This book was released on 2014-01-20 with total page 187 pages. Available in PDF, EPUB and Kindle. Book excerpt: The National Nanotechnology Initiative (NNI) is a multiagency, multidisciplinary federal initiative comprising a collection of research programs and other activities funded by the participating agencies and linked by the vision of "a future in which the ability to understand and control matter at the nanoscale leads to a revolution in technology and industry that benefits society." As first stated in the 2004 NNI strategic plan, the participating agencies intend to make progress in realizing that vision by working toward four goals. Planning, coordination, and management of the NNI are carried out by the interagency Nanoscale Science, Engineering, and Technology (NSET) Subcommittee of the National Science and Technology Council (NSTC) Committee on Technology (CoT) with support from the National Nanotechnology Coordination Office (NNCO). Triennial Review of the National Nanotechnology Initiative is the latest National Research Council review of the NNI, an assessment called for by the 21st Century Nanotechnology Research and Development Act of 2003. The overall objective of the review is to make recommendations to the NSET Subcommittee and the NNCO that will improve the NNI's value for basic and applied research and for development of applications in nanotechnology that will provide economic, societal, and national security benefits to the United States. In its assessment, the committee found it important to understand in some detail-and to describe in its report-the NNI's structure and organization; how the NNI fits within the larger federal research enterprise, as well as how it can and should be organized for management purposes; and the initiative's various stakeholders and their roles with respect to research. Because technology transfer, one of the four NNI goals, is dependent on management and coordination, the committee chose to address the topic of technology transfer last, following its discussion of definitions of success and metrics for assessing progress toward achieving the four goals and management and coordination. Addressing its tasks in this order would, the committee hoped, better reflect the logic of its approach to review of the NNI. Triennial Review of the National Nanotechnology Initiative also provides concluding remarks in the last chapter.

Assessing Nanoparticle Risks to Human Health

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Author :
Publisher : William Andrew
ISBN 13 : 0323354084
Total Pages : 286 pages
Book Rating : 4.3/5 (233 download)

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Book Synopsis Assessing Nanoparticle Risks to Human Health by : Gurumurthy Ramachandran

Download or read book Assessing Nanoparticle Risks to Human Health written by Gurumurthy Ramachandran and published by William Andrew. This book was released on 2016-07-21 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: Assessing Nanoparticle Risks to Human Health provides a systematic overview of nanoparticle risks and considers the limitations of this paradigm in a context where extreme uncertainties prevail. As well as exploring conventional risk assessment methodology, the contributing authors investigate several alternate approaches. The adequacy of current frameworks for risk management and regulatory oversights, including corporate approaches in the US and EU, are explored, and suggestions are made as to how these frameworks can be modified to make them more efficient and effective. Presenting a coherent framework for analysis of the available information, this book presents the latest scientific understanding of the toxicity and health effects of nanoparticles, the technical issues relating to exposure assessment and management, and the ways in which the current risk paradigm can be used/modified to deal with the challenges of nanoparticle risks. All chapters of this new edition have been thoroughly updated to reflect the many changes in the field since the first edition. Additions and updates in the second edition of the book include: New exposure assessment strategies for nanomaterials including life cycle exposure assessment approaches and detailed information on nanoparticle exposure control and protection in the workplace. A state-of-the-art scientific update on the hazard and risk assessment of nanomaterials: discussion of key additional publications on the toxicology and biokinetics of nanomaterials; available data and methods to characterize the health hazard and risk of exposure to nanomaterials in the workplace; additional examples of the use of such data and methods to develop occupational safety and health guidance; and discussion of progress to date, ongoing efforts, and remaining challenges in nanomaterials hazard and risk characterization. New studies on the use of expert judgment in nanotechnology. Quantitative data from Lawrence Berkeley National Laboratory’s 4-phase study. A description and evaluation of new CB tools and new ISO technical specifications. A comprehensive update of the legal frameworks in the US and the EU. With the second edition of Assessing Nanoparticle Risks to Human Health Prof. Ramachandran provides researchers and practitioners producing or using nanoparticles, or those involved in nanomaterials risk assessments, technology, health science, policy, safety, environment and regulatory aspects an invaluable reference to adopt the right technologies and strategies and to comply to legal frameworks and regulations. For policy makers and advisory firms it provides the knowledge needed to advise on compliance with or development of new regulations on nanomaterials. Makes essential reading for risk assessment professionals, companies working with nanoparticles, nanotechnology research groups and regulators Explores the use of risk assessment methodologies in an occupational health setting, and their limitations Provides a framework for evidence-based decision making in a context with many uncertainties

Global Energy Assessment

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Author :
Publisher : Cambridge University Press
ISBN 13 : 052118293X
Total Pages : 1885 pages
Book Rating : 4.5/5 (211 download)

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Book Synopsis Global Energy Assessment by : Thomas B. Johansson

Download or read book Global Energy Assessment written by Thomas B. Johansson and published by Cambridge University Press. This book was released on 2012-08-27 with total page 1885 pages. Available in PDF, EPUB and Kindle. Book excerpt: Independent, scientifically based, integrated, policy-relevant analysis of current and emerging energy issues for specialists and policymakers in academia, industry, government.

Encyclopedia of Nanoscience and Society

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Author :
Publisher : SAGE
ISBN 13 : 1412969875
Total Pages : 1025 pages
Book Rating : 4.4/5 (129 download)

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Book Synopsis Encyclopedia of Nanoscience and Society by : David H. Guston

Download or read book Encyclopedia of Nanoscience and Society written by David H. Guston and published by SAGE. This book was released on 2010 with total page 1025 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Labeled either as the 'next industrial revolution' or as just 'hype', nanoscience and nanotechnologies are controversial, touted by some as the likely engines of spectacular transformation of human societies and even human bodies, and by others as conceptually flawed. These challenges make an encyclopedia of nanoscience and society an absolute necessity. Providing a guide to what these understandings and challenges are about, the Encyclopedia of Nanoscience and Society offers accessible descriptions of some of the key technical achievements of nanoscience along with its history and prospects. Rather than a technical primer, this encyclopedia instead focuses on the efforts of governments around the world to fund nanoscience research and to tap its potential for economic development as well as to assess how best to regular a new technology for the environmental, occupational, and consumer health and safety issues related to the field. Contributions examine and analyze the cultural significance of nanoscience and nanotechnologies and describe some of the organizations, and their products, that promise to make nanotechnologies a critical part of the global economy. Written by noted scholars and practitioners from around the globe, these two volumes offer nearly 500 entries describing the societal aspects of nanoscience and nanotechnology."--Publisher's description.

Understanding Nanomedicine

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Author :
Publisher : CRC Press
ISBN 13 : 9814316385
Total Pages : 526 pages
Book Rating : 4.8/5 (143 download)

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Book Synopsis Understanding Nanomedicine by : Rob Burgess

Download or read book Understanding Nanomedicine written by Rob Burgess and published by CRC Press. This book was released on 2012-06-18 with total page 526 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book comprehensively covers a broad range of therapeutic and diagnostic applications of nanotechnology, providing descriptions of cutting-edge discoveries along with historical perspectives. The text focuses on nanomaterials and nanoparticles, the sectors that hold the most promise for the future of medicine. The author look at how nanotechnology can impact cancer treatment, clinical neuroscience, tissue engineering, drug delivery, and diagnostics. He also discusses the worldwide governmental regulatory impact on nanomedicine.

A Review of the NIOSH Roadmap for Research on Asbestos Fibers and Other Elongate Mineral Particles

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Author :
Publisher : National Academies Press
ISBN 13 : 0309140153
Total Pages : 134 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis A Review of the NIOSH Roadmap for Research on Asbestos Fibers and Other Elongate Mineral Particles by : National Research Council

Download or read book A Review of the NIOSH Roadmap for Research on Asbestos Fibers and Other Elongate Mineral Particles written by National Research Council and published by National Academies Press. This book was released on 2010-01-02 with total page 134 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although asbestos is no longer mined in the United States, prior and ongoing exposures to asbestos continue to contribute to respiratory diseases, including mesothelioma, lung cancer, and asbestosis. To examine ongoing issues and concerns in this field, the National Institute for Occupational Safety and Health (NIOSH) drafted a research roadmap, Asbestos Fibers and Other Elongated Mineral Particles: State of the Science and Roadmap for Research, that provides an overview of the state of the science and a plan for future research in areas including toxicology, mineralogy, epidemiology, and exposure assessment. The focus of the proposed research is on clarifying the relationship between human health effects and the physical and chemical characteristics of a wide range of elongate mineral particles. In 2008, NIOSH asked the Institute of Medicine and the National Research Council to form a committee to provide a review of the scientific and technical quality of the January 2009 draft NIOSH Roadmap document. The present volume provides the committee's assessment of the Roadmap and recommendations for strengthening its utility for NIOSH, other federal agencies, the private sector, and other stakeholders.

Using 21st Century Science to Improve Risk-Related Evaluations

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Author :
Publisher : National Academies Press
ISBN 13 : 0309453518
Total Pages : 201 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Using 21st Century Science to Improve Risk-Related Evaluations by : National Academies of Sciences, Engineering, and Medicine

Download or read book Using 21st Century Science to Improve Risk-Related Evaluations written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-02-16 with total page 201 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the last decade, several large-scale United States and international programs have been initiated to incorporate advances in molecular and cellular biology, -omics technologies, analytical methods, bioinformatics, and computational tools and methods into the field of toxicology. Similar efforts are being pursued in the field of exposure science with the goals of obtaining more accurate and complete exposure data on individuals and populations for thousands of chemicals over the lifespan; predicting exposures from use data and chemical-property information; and translating exposures between test systems and humans. Using 21st Century Science to Improve Risk-Related Evaluations makes recommendations for integrating new scientific approaches into risk-based evaluations. This study considers the scientific advances that have occurred following the publication of the NRC reports Toxicity Testing in the 21st Century: A Vision and a Strategy and Exposure Science in the 21st Century: A Vision and a Strategy. Given the various ongoing lines of investigation and new data streams that have emerged, this publication proposes how best to integrate and use the emerging results in evaluating chemical risk. Using 21st Century Science to Improve Risk-Related Evaluations considers whether a new paradigm is needed for data validation, how to integrate the divergent data streams, how uncertainty might need to be characterized, and how best to communicate the new approaches so that they are understandable to various stakeholders.