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Author : Anne Maria Sargeant
Publisher :
ISBN 13 :
Total Pages : 154 pages
Book Rating : 4.0/5 (21 download)
Download or read book Reverses of Fortune, a Tale for Youth written by Anne Maria Sargeant and published by . This book was released on 1835 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Eric van der Putten
Publisher : OAE Publishing Inc.
ISBN 13 :
Total Pages : 24 pages
Book Rating : 4./5 ( download)
Download or read book Ritonavir reverses resistance to docetaxel and cabazitaxel in prostate cancer cells with acquired resistance to docetaxel written by Eric van der Putten and published by OAE Publishing Inc.. This book was released on 2024-01-31 with total page 24 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aim: Docetaxel is a microtubule-stabilizing drug used for the treatment of several cancers, including prostate cancer. Resistance to docetaxel can either occur through intrinsic resistance or develop under therapeutic pressure, i.e., acquired resistance. A possible explanation for the occurrence of acquired resistance to docetaxel is increased drug efflux via P-glycoprotein (P-gp) drug transporters. Methods: We have generated docetaxel-resistant cell lines DU-145DOC10 and 22Rv1DOC8 by exposing parental cell lines DU-145DOC and 22Rv1 to increasing levels of docetaxel. Gene expression levels between DU-145DOC10 and 22Rv1DOC8 were compared with those of their respective originator cell lines. Both parental and resistant cell lines were treated with the taxane drugs docetaxel and cabazitaxel in combination with the P-gp/CYP3A4 inhibitor ritonavir and the P-gp inhibitor elacridar. Results: In the docetaxel-resistant cell lines DU-145DOC10 and 22Rv1DOC8, the ABCB1 (P-gp) gene was highly up-regulated. Expression of the P-gp protein was also significantly increased in the docetaxel-resistant cell lines in a Western blotting assay. The addition of ritonavir to docetaxel resulted in a return of the sensitivity to docetaxel in the DU-145DOC10 and 22Rv1DOC8 to a level similar to the sensitivity in the originator cells. We found that these docetaxel-resistant cell lines could also be re-sensitized to cabazitaxel in a similar manner. In a Caco-2 P-gp transporter assay, functional inhibition of P-gp-mediated transport of docetaxel with ritonavir was demonstrated. Conclusion: Our results demonstrate that ritonavir restores sensitivity to both docetaxel and cabazitaxel in docetaxel-resistant cell lines, most likely by inhibiting P-gp-mediated drug efflux.
Author : Mary Jane Sheild
Publisher :
ISBN 13 :
Total Pages : 214 pages
Book Rating : 4.0/5 (21 download)
Download or read book Holme Park, or, The Reverses of Fortune, a tale of real life, etc written by Mary Jane Sheild and published by . This book was released on 1839 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : ROYAL SURREY ZOOLOGICAL GARDENS.
Publisher :
ISBN 13 :
Total Pages : 36 pages
Book Rating : 4.0/5 (17 download)
Download or read book Facts and Documents relating to the Reverses of the Surrey Gardens Company. By a Pensive Shareholder written by ROYAL SURREY ZOOLOGICAL GARDENS. and published by . This book was released on 1857 with total page 36 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Elizabeth Whately
Publisher :
ISBN 13 :
Total Pages : 312 pages
Book Rating : 4.R/5 (6 download)
Download or read book Reverses; or, Memoirs of the Fairfax family, by the author of 'Conversations on the life of Christ'. written by Elizabeth Whately and published by . This book was released on 1833 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt:
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Author :
Publisher :
ISBN 13 :
Total Pages : 270 pages
Book Rating : 4.0/5 (21 download)
Download or read book Reverses, or Memoirs of the Fairfax Family. By the author of “Conversations on the Life of Christ,” etc. [Mrs. E. Whately]. written by and published by . This book was released on 1833 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher :
ISBN 13 :
Total Pages : 32 pages
Book Rating : 4.0/5 (17 download)
Download or read book Louis Napoleon's Feast of Trumpets. His medals and their reverses. An attempt to shew how far the Scriptures may guide us into foresight of future probabilities written by and published by . This book was released on 1859 with total page 32 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Marilyn Singer
Publisher : Penguin
ISBN 13 : 1101627298
Total Pages : 36 pages
Book Rating : 4.1/5 (16 download)
Download or read book Follow Follow written by Marilyn Singer and published by Penguin. This book was released on 2013-02-07 with total page 36 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now one of Booklist's 30 Best Books of the Year! "Genius!" – Wired.com “Marilyn Singer's verse in Follow Follow practically dances down each page . . . the effect is miraculous and pithy.” – The Wall Street Journal Once upon a time, Mirror Mirror, a brilliant book of fairy tale themed reversos–a poetic form in which the poem is presented forward and then backward–became a smashing success. Now a second book is here with more witty double takes on well-loved fairy tales such as Thumbelina and The Little Mermaid. Read these clever poems from top to bottom and they mean one thing. Then reverse the lines and read from bottom to top and they mean something else–it is almost like magic! A celebration of sight, sound, and story, this book is a marvel to read again and again.
Author : Da MoFeiGe
Publisher : Funstory
ISBN 13 : 1637882459
Total Pages : 631 pages
Book Rating : 4.6/5 (378 download)
Download or read book Tripod Reverses the Heaven written by Da MoFeiGe and published by Funstory. This book was released on 2020-08-09 with total page 631 pages. Available in PDF, EPUB and Kindle. Book excerpt: The world all the time has the rumor, the demon star appears, the taboo goes out, the heaven and earth big rob! The ancient style is born with the demon star, known as the body of taboo by the world, the source of chaos, by the world...
Author : IARC Working Group on Reversal of Risk after Quitting Smoking. Meeting
Publisher : World Health Organization
ISBN 13 :
Total Pages : 376 pages
Book Rating : 4.3/5 ( download)
Download or read book Reversal of Risk After Quitting Smoking written by IARC Working Group on Reversal of Risk after Quitting Smoking. Meeting and published by World Health Organization. This book was released on 2007 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the 11th IARC Handbook of Cancer Prevention, and the first in a series focusing on tobacco control. It reviews the scientific literature and evaluates the evidence on changes in the risk of cancer, coronary heart disease, cerebrovascular disease, abdominal aortic aneurysm, peripheral artery disease and chronic obstructive pulmonary disease observed following smoking cessation. It considers whether the risk of dying from or of developing these diseases decreases after smoking cessation, the time course of the change in risk and whether the risk returns to that of never-smokers? The review and evaluation presented in the Handbook goes on to identify relevant public health and research recommendations.
Author : Neal Barnard
Publisher : Rodale Books
ISBN 13 : 163565128X
Total Pages : 393 pages
Book Rating : 4.6/5 (356 download)
Download or read book Dr. Neal Barnard's Program for Reversing Diabetes written by Neal Barnard and published by Rodale Books. This book was released on 2018-02-27 with total page 393 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tackle diabetes and its complications for good with this newly updated edition of Dr. Neal Barnard's groundbreaking program. Revised and updated, this latest edition of Dr. Barnard’s groundbreaking book features a new preface, updates to diagnostic and monitoring standards, recent research studies, and fresh success stories of people who have eliminated their diabetes by following this life-changing plan. Before Dr. Barnard’s scientific breakthrough, most health professionals believed that once you developed diabetes, you were stuck with it—and could anticipate one health issue after another, from worsening eyesight and nerve symptoms to heart and kidney problems. But this simply is not true—Dr. Barnard has shown that it is often possible to improve insulin sensitivity and tackle type 2 diabetes by following his step-by-step plan, which includes a healthful vegan diet with plenty of recipes to get started, an exercise guide, advice about taking supplements and tracking progress, and troubleshooting tips.
Author :
Publisher :
ISBN 13 :
Total Pages : 496 pages
Book Rating : 4.2/5 (727 download)
Download or read book Man written by and published by . This book was released on 1921 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Dr. Jason Fung
Publisher : Greystone Books Ltd
ISBN 13 : 1771642661
Total Pages : 245 pages
Book Rating : 4.7/5 (716 download)
Download or read book The Diabetes Code written by Dr. Jason Fung and published by Greystone Books Ltd. This book was released on 2018-04-03 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: FROM NEW YORK TIMES BESTSELLING AUTHOR DR. JASON FUNG • “The doctor who invented intermittent fasting.” —The Daily Mail “Dr. Fung reveals how [type 2 diabetes] can be prevented and also reversed using natural dietary methods instead of medications … This is an important and timely book. Highly recommended.” —Dr. Mark Hyman, author of The Pegan Diet “Dr. Jason Fung has done it again. … Get this book!” —Dr. Steven R. Gundry, author of The Plant Paradox Everything you believe about treating type 2 diabetes is wrong. Today, most doctors, dietitians, and even diabetes specialists consider type 2 diabetes to be a chronic and progressive disease—a life sentence with no possibility of parole. But the truth, as Dr. Fung reveals in this groundbreaking book, is that type 2 diabetes is reversible. Writing with clear, persuasive language, Dr. Fung explains why conventional treatments that rely on insulin or other blood-glucose-lowering drugs can actually exacerbate the problem, leading to significant weight gain and even heart disease. The only way to treat type 2 diabetes effectively, he argues, is proper dieting and intermittent fasting—not medication. “The Diabetes Code is unabashedly provocative yet practical ... a clear blueprint for everyone to take control of their blood sugar, their health, and their lives.”—Dr. Will Cole, author of Intuitive Fasting
Author : Caldwell B. Esselstyn Jr. M.D.
Publisher : Penguin
ISBN 13 : 1583333002
Total Pages : 329 pages
Book Rating : 4.5/5 (833 download)
Download or read book Prevent and Reverse Heart Disease written by Caldwell B. Esselstyn Jr. M.D. and published by Penguin. This book was released on 2008-01-31 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: The New York Times bestselling guide to the lifesaving diet that can both prevent and help reverse the effects of heart disease Based on the groundbreaking results of his twenty-year nutritional study, Prevent and Reverse Heart Disease by Dr. Caldwell Esselstyn illustrates that a plant-based, oil-free diet can not only prevent the progression of heart disease but can also reverse its effects. Dr. Esselstyn is an internationally known surgeon, researcher and former clinician at the Cleveland Clinic and a featured expert in the acclaimed documentary Forks Over Knives. Prevent and Reverse Heart Disease has helped thousands across the country, and is the book behind Bill Clinton’s life-changing vegan diet. The proof lies in the incredible outcomes for patients who have followed Dr. Esselstyn's program, including a number of patients in his original study who had been told by their cardiologists that they had less than a year to live. Within months of starting the program, all Dr. Esselstyn’s patients began to improve dramatically, and twenty years later, they remain free of symptoms. Complete with more than 150 delicious recipes perfect for a plant-based diet, the national bestseller Prevent and Reverse Heart Disease explains the science behind the simple plan that has drastically changed the lives of heart disease patients forever. It will empower readers and give them the tools to take control of their heart health.
Author :
Publisher :
ISBN 13 :
Total Pages : 586 pages
Book Rating : 4.0/5 ( download)
Download or read book China Journal of Science and Arts written by and published by . This book was released on 1926 with total page 586 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Philip William Pode Carlyon-Britton
Publisher :
ISBN 13 :
Total Pages : 536 pages
Book Rating : 4.3/5 (91 download)
Download or read book British Numismatic Journal and Proceedings of the British Numismatic Society written by Philip William Pode Carlyon-Britton and published by . This book was released on 1959 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Barbara Stuber
Publisher : Simon and Schuster
ISBN 13 : 1442497351
Total Pages : 352 pages
Book Rating : 4.4/5 (424 download)
Download or read book Girl in Reverse written by Barbara Stuber and published by Simon and Schuster. This book was released on 2015-05-12 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Lillian Firestone is Chinese, but the kids in her 1951 Kansas City high school can't separate her from the North Koreans that America is at war with. Sick of the racism she faces at school and frustrated that her adoptive white family just sees it as 'teasing,' Lily begins to search for her birth mother"
