Retinoids

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Retinoids in Dermatology

Author : Ayse Serap Karadag
Publisher : CRC Press
ISBN 13 : 0429852614
Total Pages : 508 pages
Book Rating : 4.4/5 (298 download)

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Book Synopsis Retinoids in Dermatology by : Ayse Serap Karadag

Download or read book Retinoids in Dermatology written by Ayse Serap Karadag and published by CRC Press. This book was released on 2019-10-28 with total page 508 pages. Available in PDF, EPUB and Kindle. Book excerpt: Retinoids are valuable drugs in the dermatologic armamentarium, being employed in daily clinical practice. The text provides an in-depth update on the latest thinking on pharmacology, clinical use, side effects, and follow-up of retinoid therapy in dermatology; it also addresses topics related to retinoid use in special circumstances, such as vulnerable populations, concomitant surgery, and aesthetic procedures. CONTENTS: The background of retinoids * Mechanism of action of vitamin A * Mechanism of action of topical retinoids * Mechanism of action of isotretinoin * Mechanism of action of acitretin * Mechanism of action of bexarotene * Mechanism of action of alitretinoin * Effects of retinoids at the cellular level (differentiation, apoptosis, autophagy, cell cycle regulation, and senescence) * Effects of retinoids at the systemic level * New aspects of isotretinoin teratogenicity * Mucocutaneous side effects * Ophthalmologic side effects * Musculoskeletal side effects * Neurologic side effects * Psychiatric side effects * Gastrointestinal side effects * Endocrine and metabolic side effecs * Other systemic side effects: Cardiovascular, pulmonary, otolaryngorhinologic, genitourinary, renal, and immunologic * Retinoids in acne * Retinoids in hidradenitis suppurativa/acne inversa * Retinoids in rosacea * Retinoids in hair disorders * Retinoids in psoriasis * Retinoids in keratinization disorders * Retinoids in antiaging therapy * Retinoids in other skin diseases * Retinoids in lymphoma * Retinoids in cutaneous chemoprophylaxis * Guide to good clinical practice for vulnerable populations (infancy, childhood, fertile period, elderly) * Retinoids and concomitant surgery * Retinoids and concomitant aesthetic procedures * Laboratory and clinical follow-up * Teratogenicity and registry programs * Management of vitamin A and retinoid side effects * Future and novel unexplored indications of retinoids Published in association with the Journal of Dermatological Treatment.

The Retinoids

Author : Pascal Dollé
Publisher : John Wiley & Sons
ISBN 13 : 1118627903
Total Pages : 608 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis The Retinoids by : Pascal Dollé

Download or read book The Retinoids written by Pascal Dollé and published by John Wiley & Sons. This book was released on 2015-05-18 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Retinoids: Biology, Biochemistry, and Disease provides an overview and synthesis of the retinoid molecules, from basic biology to mechanisms of diseases and therapy. Divided into five sections, the book covers retinoic acid signaling from biochemical, genetic, developmental, and clinical perspectives. The text is divided into five sections, the first of which examines vitamin A metabolic and enzymatic pathways. Focus then shifts to the role of retinoic acid signaling in development, and then to retinoids and physiological function. The book concludes with chapters on retinoids, disease and therapy. Comprehensive in scope and written by leading researchers in the field, The Retinoids: Biology, Biochemistry, and Disease will be an essential reference for biologists, biochemists, geneticists and developmental biologists, as well as for clinicians and pharmacists engaged in clinical research involving retinoids.

Retinoids in Oncology

Author : Waun Ki Hong
Publisher : CRC Press
ISBN 13 : 9780824790486
Total Pages : 356 pages
Book Rating : 4.7/5 (94 download)

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Book Synopsis Retinoids in Oncology by : Waun Ki Hong

Download or read book Retinoids in Oncology written by Waun Ki Hong and published by CRC Press. This book was released on 1993-05-11 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: This reference provides a comprehensive overview of recent developments in basic research that are relevant to the application of retinoids for cancer prevention and treatment.;Organized in a quick-referral format by specific disease site, this book: describes the effects of retinoids on squamous differentiation in normal, pre-malignant, and malignant epithelial tissues; addresses the mechanisms by which cultured keratinocytes respond to retinoids; considers the antitumor activity of combination therapy with retinoids and cytokines; reviews the toxicity profiles of the vitamin A molecule and the synthetically derived retinoid compounds and their effects on humans; examines the use of retinoids in the prevention of basal cell carcinoma and squamous cell carcinoma (SCC) and in the therapy of advanced SCC; and summarizes data on the potential of retinoids to prevent epithelial cancer, to act as adjuvants to current therapies in early stages of the disease and to aid in the management of both solid tumours and hematologic malignancies.;A guide for the many disciplines involved in the preclinical studies and direct care of cancer patients, this book serves as useful reading for clinical, surgical and radiation oncologists; clinical immunologists; dermatologists; obstetricians/gynaecologists; haematologists; otolaryngologists; internists; nutritionists; and pulmonary-disease specialists.

Cosmetic Dermatology

Author : Zoe Diana Draelos
Publisher : John Wiley & Sons
ISBN 13 : 1118655486
Total Pages : 560 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis Cosmetic Dermatology by : Zoe Diana Draelos

Download or read book Cosmetic Dermatology written by Zoe Diana Draelos and published by John Wiley & Sons. This book was released on 2015-10-08 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: Back for a new edition, Zoe Draelos' outstanding resource to cosmetic dermatology again provides a highly-illustrated, clinical guide to the full range of cosmetic skin treatments. Bringing together experts from research, industry, surgery and practice, it is structured in four distinct parts for easy navigation by the busy clinician: Basic Concepts - giving an overview of the physiology pertinent to cosmetic dermatology and the delivery systems by which treatments can take effect; Hygiene Products - evaluating cleansing and moisturising products; Adornment - looking at aesthetic techniques such as cosmetics, nail protheses and hair treatment; Antiaging - ie, injectables, resurfacing and skin contouring techniques, and the rapidly growing area of Cosmeceuticals. With over 300 high-quality images and key summary boxes throughout, this new edition incorporates the newest procedural innovations in this rapidly developing field. Perfect for all dermatologists, especially those specialising in cosmetic dermatology and whether hospital-based or in private practice, it provides the complete cosmetic regimen for your patients and will be an indispensable tool to consult over and over again.

Vitamin A and Retinoids: An Update of Biological Aspects and Clinical Applications

Author : Maria A. Livrea
Publisher : Birkhäuser
ISBN 13 : 3034884540
Total Pages : 301 pages
Book Rating : 4.0/5 (348 download)

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Book Synopsis Vitamin A and Retinoids: An Update of Biological Aspects and Clinical Applications by : Maria A. Livrea

Download or read book Vitamin A and Retinoids: An Update of Biological Aspects and Clinical Applications written by Maria A. Livrea and published by Birkhäuser. This book was released on 2012-12-06 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rapid progress has been made in our understanding of the molecular mechanisms of cell growth and oncogenesis during the past decade. Special attention has been given to the presentation of the frequently neglected close correlation between changes in signal transduction and metabolic pathways during oncogenesis. This book advances the knowledge of mechanisms regulating metabolism and functioning of vitamin A and offers the most recent results of research on the clinical efficiency of retinoids in skin disorders and cancer. The book presents recent findings on the regulation of cell growth in normal and neoplastic tissues by growth factors including hormones, and by the activation and inactivation of oncogenes and tumor suppressor genes, respectively. It also offers a survey of the molecular and cell biochemistry of retinoids. Basic researchers in biochemistry, pharmacology and cell biology as well as clinicians will find this book very informative and up-to-date. This book advances the knowledge of mechanisms regulating metabolism and functioning of vitamin A and offers the most recent results of research on clinical efficiency of retinoids in skin disorders and cancer. Basic researchers in biochemistry, pharmacology, cell biology, and clinicians will find this book very informative and up-to-date. The chapters, organized in six sections, are contributed by leading scientists who have been working in the retinoid field for decades. Their experience and competence is aknowledged worldwide.

Retinoids and Carotenoids in Dermatology

Author : Anders Vahlquist
Publisher : CRC Press
ISBN 13 : 1420021184
Total Pages : 390 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Retinoids and Carotenoids in Dermatology by : Anders Vahlquist

Download or read book Retinoids and Carotenoids in Dermatology written by Anders Vahlquist and published by CRC Press. This book was released on 2007-06-20 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: This up-to-date reference describes how retinoids and carotenoids function in the skin and how they can be utilized to prevent and treat a wide variety of skin diseases, as well as advance biomedical research in relation to cancer treatment and immunology. Providing an in-depth update on the pharmacology, pharmacodynamics, and new applications of

Retinoids

Author : Maria A Livrea
Publisher : CRC Press
ISBN 13 : 9780824787585
Total Pages : 682 pages
Book Rating : 4.7/5 (875 download)

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Book Synopsis Retinoids by : Maria A Livrea

Download or read book Retinoids written by Maria A Livrea and published by CRC Press. This book was released on 1993-01-18 with total page 682 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains papers presented at the Conference on Retinoids: New Trends in Research and Clinical Applications, held in 1991 in Palermo, Italy, describing the latest research findings on biochemistry, nutrition, molecular and cell biology and developmental biology, as well as the pharmacology and the therapeutic use of vitamin A and its congeners.;Written by leading authorities in the field from the USA, Europe and Japan, Retinoids, amongst other things: addresses retinol-supported retinoic acid (RA) synthesis and catabolism; identifies synthetic ligands with a high selective affinity for RAR-alpha, -beta and -gamma nuclear receptors, determining if they would show pharmacological properties similar to the natural parent substance all-trans RA; considers the embryonic/foetal cellular retinoid-binding proteins and evidence for their participation in normal and abnormal morphogenesis; discusses a novel arotinoid, Ro 40-8757, that exhibited improved anti-tumour efficacy and safety in pre-clinical tests; and reports the audioradiographic distribution of retinol and RA in organs of pregnant hamsters and foetuses.

Nutritional Biochemistry of the Vitamins

Author : David A. Bender
Publisher : Cambridge University Press
ISBN 13 : 1139437739
Total Pages : 514 pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis Nutritional Biochemistry of the Vitamins by : David A. Bender

Download or read book Nutritional Biochemistry of the Vitamins written by David A. Bender and published by Cambridge University Press. This book was released on 2003-09-18 with total page 514 pages. Available in PDF, EPUB and Kindle. Book excerpt: An authoritative and comprehensive review of our current knowledge of the vitamins, their metabolic functions and the scientific basis for setting recommended intakes for the prevention of deficiency and promotion of optimum health. This publication will be a valuable reference for students and specialists alike in the field of nutritional biochemistry.

Chemistry and Biology of Synthetic Retinoids

Author : Marcia I. Dawson
Publisher : CRC Press
ISBN 13 : 1351079085
Total Pages : 627 pages
Book Rating : 4.3/5 (51 download)

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Book Synopsis Chemistry and Biology of Synthetic Retinoids by : Marcia I. Dawson

Download or read book Chemistry and Biology of Synthetic Retinoids written by Marcia I. Dawson and published by CRC Press. This book was released on 2018-01-18 with total page 627 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of this book is to present an overview of advances in both retinal and retinoic acid synthetic chemistry and biology. Chapters are written by research workers who are active in these fields. Emphasis is placed on structure-activity relationships. It includes topics of cell differentiation, maintenance of cell morphology, and vision. This reference contains a special section on assays which were developed to measure retinoid activity. This book is ideal for those interested in the fields of photobiology, organic chemistry, biological chemistry, and nutrition.

Retinoid Signaling Pathways

Author :
Publisher : Academic Press
ISBN 13 : 0128201479
Total Pages : 612 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Retinoid Signaling Pathways by :

Download or read book Retinoid Signaling Pathways written by and published by Academic Press. This book was released on 2020-04-29 with total page 612 pages. Available in PDF, EPUB and Kindle. Book excerpt: Retinoid Signaling Pathways, Volume 637, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Sections in this release include The chemistry and biochemistry of Vitamin A and its natural derivative, Biosynthesis of retinoic acids, Biodegration of retinoic acids mediated by retinoid binding proteins, Retinoic acid homeostasis, Cryo Electron Microscopy to study retinol update via the STRA6 receptor, Immuno-detection of retinoic acid synthesis enzymes in the brain, classical pathway of gene regulation by retinoids, Protein-protein interactions in the regulation of retinoid acid receptors activity, and much more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Methods in Enzymology series Includes the latest information on retinoid signaling pathways

Retinoids

Author : Heinz Nau
Publisher : Springer Science & Business Media
ISBN 13 : 3642584837
Total Pages : 631 pages
Book Rating : 4.6/5 (425 download)

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Book Synopsis Retinoids by : Heinz Nau

Download or read book Retinoids written by Heinz Nau and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 631 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the future' the decade of the 1990s will likely be viewed as a Golden Age for retinoid research. There have been unprecedented research gains in the understanding of retinoid actions and physiology; since the retinoid nuclear receptors were first identified and the importance of retinoic acid in develop mental processes was first broadly recognized in the late 1980s. Between then and now, our knowledge of retinoid action has evolved from one of a near complete lack of understanding of how retinoids act within cells to one of sophisticated understanding of the molecular processes through which retinoids modulate transcription. In this volume, we have tried to provide a comprehensive update of the present understanding of retinoid actions, with an emphasis on re cent advances. The initial chapters of the volume, or Section A, focus on the physicochemical properties and metabolism of naturally occurring retinoids: - N OY provides an uncommonly encountered view of retinoid effects from the perspective of the physiochemical properties of retinoids. - V AKIANI and BUCK lend a perspective on the biological occurrence and actions of retro- and anhydro-retinoids. Section B considers both the retinoid nuclear receptors and their mechanisms of action as well as synthetic retinoids that have been used exper imentally to provide mechanistic insights into receptor actions and have potential therapeutic use for treating disease: - PIEDRAFITA and PFAHL provide a comprehensive review of retinoid nuclear receptor biochemistry and molecular biology.

Retinoids

Author : C.E. Orfanos
Publisher : Springer Science & Business Media
ISBN 13 : 3642680232
Total Pages : 500 pages
Book Rating : 4.6/5 (426 download)

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Book Synopsis Retinoids by : C.E. Orfanos

Download or read book Retinoids written by C.E. Orfanos and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the aromatic retinoic acid analog Tigason oral and intravenous pharmacokinetic studies have been performed in 5 normal volunteers. Simultaneous fitting of single i. v. and oral data to a three-compartment model assuming first-order absorption was possible. Using Nonlin parameter estimates of the single-dose data, one is able to predict the decline in plasma levels of parent drug following cessation of a 10 days multiple dosing regimen up to 24 hours. The model is however unable to predict a phase of prolonged elimination observed beyond 24 hours. Moreover in 5 patients, who underwent chronic therapy (8-15 months), substantial plasma levels of both unchanged drug and main metabolite (corre sponding carboxylic acid) were observed up to 140 days after cessation of the therapy. An apparent half-life of elimination of 80-100 days can be calculated. The drug appears to be stored at some yet unknown storage site. Investigation of metabolism of Tigason in rats and humans revealed 19 different bio transformation products thus far, most of them appearing in the urine in low amounts (20010 of dose). A few of them (mainly the acid Ro 10-1670) after conjugation to glucuronic acid are excreted in the bile in high amounts (60-80% of dose). No drug appeared unchanged in the excreta after i. v. administration to rats. References 1. Bollag W (1971) Effects of vitamin A acid (NSC-122758) on transplantable and chemically-induced tumors. Cancer Chemother Rep 55:53-58 2.

The Retinoids: v. 2

Author : BAERT ET BAERT ET AL
Publisher : Academic Press
ISBN 13 : 1483296377
Total Pages : 463 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis The Retinoids: v. 2 by : BAERT ET BAERT ET AL

Download or read book The Retinoids: v. 2 written by BAERT ET BAERT ET AL and published by Academic Press. This book was released on 2014-06-28 with total page 463 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Retinoids: v. 2

Comprehensive Dermatologic Drug Therapy

Author : Stephen E. Wolverton
Publisher : Elsevier Health Sciences
ISBN 13 : 0323612121
Total Pages : 858 pages
Book Rating : 4.3/5 (236 download)

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Book Synopsis Comprehensive Dermatologic Drug Therapy by : Stephen E. Wolverton

Download or read book Comprehensive Dermatologic Drug Therapy written by Stephen E. Wolverton and published by Elsevier Health Sciences. This book was released on 2019-12-14 with total page 858 pages. Available in PDF, EPUB and Kindle. Book excerpt: Designed with practical usability in mind, Comprehensive Dermatologic Drug Therapy, 4th Edition, helps you safely and effectively treat the skin disorders you’re likely to see in your practice. Dr. Stephen E. Wolverton and new associate editor Dr. Jashin J. Wu lead a team of global experts to bring you concise, complete guidance on today's full spectrum of topical, intralesional, and systemic drugs. You’ll prescribe with confidence thanks to expert coverage of which drugs to use, when to use them, and adverse effects to monitor. Includes new drug interaction tables, drug risk profiles, and FDA guidelines, as well as two new appendices that summarize chapter questions and summarize highest-risk drug interactions. Covers the best uses for new biologic therapeutics. Contains new chapters covering medical decision-making principles, PDE-4 and JAK inhibitors, interleukin 17 inhibitors, interleukin 23 inhibitors, additional biologic therapeutics, and hedgehog pathway inhibitors. Contains quick-access summaries of indications/contraindications, dosage guidelines, drug interactions, drug monitoring guidelines, adverse effects, and treatment protocols. Features a highly detailed, disease-specific index, as well as purchase information for major drugs. Helps you assess your knowledge and prepare for certification or recertification with about 800 review questions and answers throughout the book.

Retinoids, Differentiation and Disease

Author : Jonathan Nugent
Publisher : John Wiley & Sons
ISBN 13 : 0470718641
Total Pages : 192 pages
Book Rating : 4.4/5 (77 download)

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Book Synopsis Retinoids, Differentiation and Disease by : Jonathan Nugent

Download or read book Retinoids, Differentiation and Disease written by Jonathan Nugent and published by John Wiley & Sons. This book was released on 2009-09-14 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.

Retinoids in Oncology

Author : Waun Ki Hong
Publisher : CRC Press
ISBN 13 : 100014822X
Total Pages : 356 pages
Book Rating : 4.0/5 (1 download)

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Book Synopsis Retinoids in Oncology by : Waun Ki Hong

Download or read book Retinoids in Oncology written by Waun Ki Hong and published by CRC Press. This book was released on 2020-07-24 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: This reference provides a comprehensive overview of recent developments in basic research that are relevant to the application of retinoids for cancer prevention and treatment.;Organized in a quick-referral format by specific disease site, this book: describes the effects of retinoids on squamous differentiation in normal, pre-malignant, and malignant epithelial tissues; addresses the mechanisms by which cultured keratinocytes respond to retinoids; considers the antitumor activity of combination therapy with retinoids and cytokines; reviews the toxicity profiles of the vitamin A molecule and the synthetically derived retinoid compounds and their effects on humans; examines the use of retinoids in the prevention of basal cell carcinoma and squamous cell carcinoma (SCC) and in the therapy of advanced SCC; and summarizes data on the potential of retinoids to prevent epithelial cancer, to act as adjuvants to current therapies in early stages of the disease and to aid in the management of both solid tumours and hematologic malignancies.;A guide for the many disciplines involved in the preclinical studies and direct care of cancer patients, this book serves as useful reading for clinical, surgical and radiation oncologists; clinical immunologists; dermatologists; obstetricians/gynaecologists; haematologists; otolaryngologists; internists; nutritionists; and pulmonary-disease specialists.

Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc

Download Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc PDF Online Free

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 9780309072793
Total Pages : 804 pages
Book Rating : 4.0/5 (727 download)

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Book Synopsis Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc by : Institute of Medicine

Download or read book Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc written by Institute of Medicine and published by National Academies Press. This book was released on 2002-07-19 with total page 804 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is the newest release in the authoritative series issued by the National Academy of Sciences on dietary reference intakes (DRIs). This series provides recommended intakes, such as Recommended Dietary Allowances (RDAs), for use in planning nutritionally adequate diets for individuals based on age and gender. In addition, a new reference intake, the Tolerable Upper Intake Level (UL), has also been established to assist an individual in knowing how much is "too much" of a nutrient. Based on the Institute of Medicine's review of the scientific literature regarding dietary micronutrients, recommendations have been formulated regarding vitamins A and K, iron, iodine, chromium, copper, manganese, molybdenum, zinc, and other potentially beneficial trace elements such as boron to determine the roles, if any, they play in health. The book also: Reviews selected components of food that may influence the bioavailability of these compounds. Develops estimates of dietary intake of these compounds that are compatible with good nutrition throughout the life span and that may decrease risk of chronic disease where data indicate they play a role. Determines Tolerable Upper Intake levels for each nutrient reviewed where adequate scientific data are available in specific population subgroups. Identifies research needed to improve knowledge of the role of these micronutrients in human health. This book will be important to professionals in nutrition research and education.