Restenosis after Intervention with New Mechanical Devices

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Publisher : Springer Science & Business Media
ISBN 13 : 940112650X
Total Pages : 500 pages
Book Rating : 4.4/5 (11 download)

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Book Synopsis Restenosis after Intervention with New Mechanical Devices by : P.W. Serruys

Download or read book Restenosis after Intervention with New Mechanical Devices written by P.W. Serruys and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: From the Foreword by Eric J. Topol In the past five years, interventional cardiology has entered a new era of evaluating percutaneous transcatheter technologies to treat coronary artery disease and prevent restenosis. Cardiologists attempting to follow this new and exciting field may easily be confused by the growth and expansion of new devices, the technical details relevant to each device and enthusiastic claims of success. This monograph is a comprehensive and objective assessment of restenosis from the perspective of these new technologies including stenting, atherectomy, rotational abrasion and lasers, written by innovators and pioneers. The international breadth of experience is reflected in the summary of experiences from both sides of the Atlantic, at times with conflicting observations and results which in itself is valuable, given the diverse experience to date. In addition to the lucid summaries of the early and late results of these new devices, important issues in the methodology of restenosis research are addressed, including limitations of quantitative coronary arteriography in evaluating the new devices and important advances in alternatives to arteriography such as intravascular imaging. As a whole, this monograph is exceptionally worthwhile owing to its complete, up-to-date, balanced and visionary elements. There is no question that the new coronary device era has ushered in some excitement, and some despair. This book serves a pivotal purpose by weaving so many new concepts together, establishing the groundwork for further development of mechanical approaches to limit restenosis. I heartily recommend this text to all interventional cardiologists interested in practical and research aspects of restenosis.

Molecular Cardiology for the Cardiologists

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Publisher : Springer Science & Business Media
ISBN 13 : 1461520193
Total Pages : 266 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Molecular Cardiology for the Cardiologists by : Bernard Swynghedauw

Download or read book Molecular Cardiology for the Cardiologists written by Bernard Swynghedauw and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Cardiology for the Cardiologist provides a short, easily readable summary of what the new biology brings to cardiology. With this in mind, special efforts have been made to present many comprehensive schemes and drawings, as well as teaching tables. The five parts of the book provide a general introduction to the new language of biology; the normal structure of the heart and blood vessels; the physiopathology and the new therapeutic avenues that have been opened up by the new biology. A concise summary of the keys that assist the cardiologist or student who seeks to learn and read more about this field. Provides practical examples to illustrate the clinical interest of the new approach.

Animal models in cardiovascular research

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Publisher : Springer Science & Business Media
ISBN 13 : 9401707308
Total Pages : 512 pages
Book Rating : 4.4/5 (17 download)

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Book Synopsis Animal models in cardiovascular research by : D.R. Gross

Download or read book Animal models in cardiovascular research written by D.R. Gross and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: Interest in the humane and scientifically justifiable use of research animals has intensified since the publication of the first edition of this textbook. This completely revised and updated text provides information essential to any researcher interested in using animal models for cardiovascular research, or any research which requires normal cardiovascular function. The format and presentation have been changed to make the text more easy to read and use. An introductory chapter offers general principles of animal selection, pre and post-operative care, preanesthesia, chemical restraint, analgesia, and the recognition of pain. The number of references cited has been almost doubled over the previous text and the chapter tabulating normal cardiovascular parameters from intact, awake animals, of those species commonly used in research, has been greatly expanded. Other chapters providing comprehensive data on the cardiovascular effects of opioids, tranquilizers, anesthetic agents and other drugs commonly used in cardiovascular research have been expanded with special emphasis on species variability to drug effects. The chapters on both naturally occurring and iatrogenic models of cardiovascular disease have also been expanded and updated.

Cardiac Positron Emission Tomography

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Publisher : Springer Science & Business Media
ISBN 13 : 1461312337
Total Pages : 384 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Cardiac Positron Emission Tomography by : Markus Schwaiger

Download or read book Cardiac Positron Emission Tomography written by Markus Schwaiger and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is the mark of an instructed mind to rest satisfied with the degree of precision which the nature of the subject admits, and not to seek exactness where only an approximation of the truth is possible. Aristotle With the development of imaging techniques, the in vivo study of human anatomy and physiology has become possible with increasing "approximation of the truth. " Advances have been made not only in data acquisition, but also in processing as well as visualization of functional and morphological data. Following the successful application of planar two-dimensional imaging approaches, more recently three-dimensional data acquisition and correspond ing tomographic image reconstruction has become possible. With the rapid growth of computer support, advanced processing allows for user-friendly interaction with complex data sets. Classical x-ray imaging techniques have matured to excellent spatial resolution and contrast, which provide specific delineation of anatomical changes occurring in cardiovascular disease. In parallel, the use of tracer principles supported the successful introduction of nuclear medicine procedures for the functional characterization of physiology and pathophysiology. The application of such techniques were initially limited by relatively poor spatial resolution, but excelled in high sensitivity 30 years, scintigraphic imaging emerged from and specificity. In the last rectilinear scanning to planar gamma camera imaging and single-photon xvi Preface emISSIOn tomography (SPECT). Based on these advances and the experi mental success of autoradiography, the potential of scintigraphy as a clinical and research tool has been well appreciated.

Electrogenesis of Biopotentials in the Cardiovascular System

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Publisher : Springer Science & Business Media
ISBN 13 : 146152590X
Total Pages : 387 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Electrogenesis of Biopotentials in the Cardiovascular System by : Nicholas Sperelakis

Download or read book Electrogenesis of Biopotentials in the Cardiovascular System written by Nicholas Sperelakis and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 387 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1979 Dr Sperelakis published the `Origin of the Cardiac Resting Potential' in the Handbook of Physiology of the Heart. Since that time, many investigators and teachers of membrane biophysics have used this article as a source of reference on the fundamental principles and equations describing the factors that establish the resting potential in excitable and non-excitable cells. Professor Sperelakis has expanded the scope of this article to provide the present book, creating a comprehensive work and an invaluable reference on the electrophysiological concepts underlying cellular excitability. There has long been a need for a text which precisely defines the assumptions underlying the derivations and equations that describe the principles of electrical excitability and maintenance of ion gradients in excitable cells. Here, Professor Sperelakis not only defines the equations and underlying concepts of membrane potentials, but gives working examples of solutions, thus allowing investigators to utilize the fundamental principles in their research, and students of membrane physiology to establish a sound basis of electrophysiological theory. `I have used the `Origin of the Cardiac Resting Potential' in graduate courses on cell physiology and biophysics, and look forward to using this new book. The time and effort required to put this work together reflects the dedication of Dr Sperelakis to the field of membrane biophysics and electrophysiology in his long, productive career.' From the Foreword by Dr David R. Harder.

Molecular Physiology and Pharmacology of Cardiac Ion Channels and Transporters

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Publisher : Springer Science & Business Media
ISBN 13 : 9401139903
Total Pages : 586 pages
Book Rating : 4.4/5 (11 download)

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Book Synopsis Molecular Physiology and Pharmacology of Cardiac Ion Channels and Transporters by : M. Morad

Download or read book Molecular Physiology and Pharmacology of Cardiac Ion Channels and Transporters written by M. Morad and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 586 pages. Available in PDF, EPUB and Kindle. Book excerpt: Knowledge of cardiac ion channels and transporters has advanced remarkably in the last two decades with the development of patch-clamp and molecular biological techniques. This textbook offers a comprehensive overview of structures and functions of ion channels and transporters in the heart. Readers are first introduced to the molecular biology and electrophysiology of all the important ion channels. After discussing their developmental changes, the pharmacology and pathophysiology of clinically-relevant ion channels are reviewed. Molecular aspects of the cardiac excitation-contraction coupling and intracellular Ca2+ regulation by ion transporters are also described. The book will be useful to electrophysiologists, cardiac physiologists and pharmacologists, and molecular biologists interested in ion channels at all levels. For research specialists, the book will provide a perspective of the field. The book can be used as a reference source for working scientists in the fields of ion channels, biophysics, cardiac electrophysiology, and pharmacology. It is aimed at graduate and medical students, designed for use as a textbook for graduate and medical courses.

Purines and Myocardial Protection

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Publisher : Springer Science & Business Media
ISBN 13 : 1461304555
Total Pages : 565 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Purines and Myocardial Protection by : Anwar-Saad A. Abd-Elfattah

Download or read book Purines and Myocardial Protection written by Anwar-Saad A. Abd-Elfattah and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 565 pages. Available in PDF, EPUB and Kindle. Book excerpt: A critical review of the most up-to-date research on purines and myocardial protection. The role of purines in reversible `myocardial stunning' and irreversible (myocardial infarction) ischemic injury, ventricular arrhythmias, and ischemic preconditioning is discussed in detail, by experts. All reviews address recent and rather controversial issues on purines and myocardial protection. Mechanisms of cardioprotection of exogenous versus endogenous purines are discussed in detail. The contribution of internationally recognized experts in the field of purines and cardiovascular physiology and in myocardial protection makes this a unique and interesting book for clinicians, basic scientists and students.

Growth Factors and the Cardiovascular System

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Publisher : Springer Science & Business Media
ISBN 13 : 1461530989
Total Pages : 398 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Growth Factors and the Cardiovascular System by : P. Cummins

Download or read book Growth Factors and the Cardiovascular System written by P. Cummins and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nature is totally amoral! There are at least 3-4 million people in France alone who suffer from arterial hypertension, and whose cardiovascular system is submitted day and night to both a haemodynamic and hormonal stress. In all cases, the vasculature hypertrophies as does the myocardium. This growth process is obviously mainly detrimental at the outset since it lowers compliance of the arteries and makes them stiffer. In contrast, myocardial hypertrophy is initially beneficial since the growth process multiplies the number of contractile units and by so doing improves external work. In addition, according to Starling's law, wall stress is lowered. Growth factors playa major role in this amoral process as a trigger for hypertrophy at the vascular level, and very likely at the level of the myocardium. Another major point of interest is the role of growth factors as determinants of restenosis after angioplasty and also of atherogenesis. Several chapters in this book are directly or indirectly concerned with this problem which is far from being purely academic since several groups are currently trying to control these processes by gene transfer. Certainly, one of the major clinical questions arising from such studies is why restenosis is not more frequent in clinical practice. After de-endotheliazation, the biologist would predict on the basis of recent studies on growth factors, and in contrast with current clinical opinion, that hypertrophy would occur in all cases with more or less complete restenosis.

Angiology in Practice

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Publisher : Springer Science & Business Media
ISBN 13 : 9401154066
Total Pages : 530 pages
Book Rating : 4.4/5 (11 download)

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Book Synopsis Angiology in Practice by : A-M. Salmasi

Download or read book Angiology in Practice written by A-M. Salmasi and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 530 pages. Available in PDF, EPUB and Kindle. Book excerpt: Arterial and venous diseases are major causes of morbidity and mortality in most of the world, especially in the western hemisphere. Not only of interest to angiologists, these illnesses are also of concern to most physicians in various fields ranging from cardiology, general medicine and cardiovascular surgery to physiology, pathology and clinical pharmacology. Specialists in diabetes, hypertension and epidemiology find these illnesses as challenging in their own fields of interest due to the gross interrelation of these diseases with their specialities. This book of 35 chapters contains an up-to-date discussion of various arterial and venous illnesses presenting major clinical applications ranging from basic pathology, haemodynamics and haemorheology to clinical features and management. Special attention has also been paid to epidemiology and prevention, discussing all the issues concerned. A special section on vascular emergency has also been included, thereby extending its usefulness to physicians and surgeons working in accident and emergency units.

Nuclear Cardiology in Everyday Practice

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Publisher : Springer Science & Business Media
ISBN 13 : 9401119848
Total Pages : 412 pages
Book Rating : 4.4/5 (11 download)

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Book Synopsis Nuclear Cardiology in Everyday Practice by : J. Candell-Riera

Download or read book Nuclear Cardiology in Everyday Practice written by J. Candell-Riera and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: The most salient feature of the infor last four chapters of the book evaluate the mation provided by nuclear medicine is its information from an analytical and pathophysiological and functional charac statistical point of view. This approach is ter. For adequate experimental or clinical required for correct decision-making. interpretation, such information should This book is therefore the result of necessarily be interpreted alongside the accumulated experience in nuclear cardiology views of the clinical cardiologist, who is with the invaluable cooperation of medical able to apply it to the individual patient. statisticians. It is directed to physicians This approach, which is routine in every with an interest in nuclear cardiology, to day clinical practice, reaches its plenitude nuclear medicine specialists wishing to when the whole process is completed and learn the uses and limitations of these an intimate cooperation is established procedures in everyday clinical cardiology, between the nuclear medicine specialist and to cardiologists who feel the need to and the clinical cardiologist. In such understand the rationale and methodology instances, each one of these professionals of the studies which benefit their patients. understands the needs, limits and possi We understand that the ultimate reason bilities of the other. for any scientific book is the transmission The present book is the fruit of such of knowledge, and we are fully conscious cooperation. In our hospital, an efficient of the enthusiasm of the authors of the nuclear cardiology team has been made up present text to achieve that aim.

Membrane Physiopathology

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Publisher : Springer Science & Business Media
ISBN 13 : 1461526167
Total Pages : 419 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Membrane Physiopathology by : Ghassan Bkaily

Download or read book Membrane Physiopathology written by Ghassan Bkaily and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 419 pages. Available in PDF, EPUB and Kindle. Book excerpt: The need for publishing acomprehensive review ofa number ofdifferent membrane pathologiesofmuscleand non-musclecells inillnesses ranging from diabetes toheart disease and cancer lies on to the fact that there are several books dealing with the properties ofnormal cell membranes, although there are very few books focussing on the abnormal membrane behavior. Since the membrane is the critical outer barrier of a cell, this membrane could be the first structure to be affected in some diseases. Research is advancing at the cellular level at a very rapid rate. We can now address questions such as: "How and by what is the mechanism underlying membrane ion channel and receptor dysfunction leading to abnormal cell function?" and "What substances cause dysfunction in specific ion channels or receptors?". Such questions bring together the microscopic worldofthecell with the macroscopic manifestation of disease. We believe that a book such as this one would help researchers, physicians, and students to better understand the relationship between cell membrane dysfunction and abnormal function of the cell and tissue. This book is intended for practicing clinicians and academic researchers, as well as resident physicians, medical studentsandgraduatestudents. Hopefully, suchtreatisewillhelp to fill an important gap between basic science and clinical science. We are greatly indebted to all thedistinguishedandhigWy-qualified researchers from university and industrial milieus who contributed to this book. Finally, we would like to thank the publishers for their confidenceand cooperation in making this book available for the medical sciences.

The Modern Era of Coronary Thrombolysis

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Publisher : Springer Science & Business Media
ISBN 13 : 1461526183
Total Pages : 308 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis The Modern Era of Coronary Thrombolysis by : Richard C. Becker

Download or read book The Modern Era of Coronary Thrombolysis written by Richard C. Becker and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: Coronary heart disease remains the leading cause of death for men and women in the United States and other industrialized nations. Acute myocardial infarction accounts for a majority of these deaths, approaching 750,000 yearly. Thrombolytic therapy has revolutionized the treatment of myocardial infarction, saving lives to a greater extent than any treatment developed to date. The identification of patients best suited for thrombolytic therapy has been a challenging task, as has the ideal adjuvant strategy. Further, the noninvasic diagnosis of treatment successes and failures, as well as the expeditious triaging of patients requiring mechanical/surgical revascularization have been difficult to define, but progress has been made recently. The emergence of information vital for patient care has appeared at an extraordinary pace, with hundreds of articles being published yearly. Unfortunately, a resource devoted to the area of thrombolysis does not exist, making the dissemination of information to physicians, scientists and health care providers problematic. The Modern Era of Coronary Thrombolysis is designed to bring the medical and scientific communities up to date. It will serve as a foundation for future investigation, as well as a resource which can be referred to for many years to come.

Ionic Channels and Effect of Taurine on the Heart

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Publisher : Springer Science & Business Media
ISBN 13 : 1461530741
Total Pages : 180 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Ionic Channels and Effect of Taurine on the Heart by : Denis Noble

Download or read book Ionic Channels and Effect of Taurine on the Heart written by Denis Noble and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is based on papers presented at a Symposium held in Seoul, Korea in 1992. The idea for the symposium developed naturally from work in which Professor Yung E Earm, at Seoul National University, had been involved both in my laboratory in Oxford and in his own laboratory in Seoul concerning the possible role of certain amino acids, like taurine that are strongly concentrated by the cells of the heart, and the relationship between such acids and membrane ionic currents. The first obvious question was whether it is possible to identify the transport mechanisms involved for taurine and whether they are electrogenic. The second question is what function could be served by such processes: does taurine play an essential role in cardiac tissue and is this important in protecting the heart from disease? With his colleagues in the Korean Physiological Society, Professor Earm set about the task of fmancing and organizing a meeting at which some of the world's leading cardiac electrophysiologists and taurine specialists could discuss these questions. The fmance was generously provided by the Dong-A Pharmaceutical Company, one of the leading scientific companies in Korea.

Bioresorbable Scaffolds

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Publisher : CRC Press
ISBN 13 : 1498779778
Total Pages : 533 pages
Book Rating : 4.4/5 (987 download)

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Book Synopsis Bioresorbable Scaffolds by : Yoshinobu Onuma

Download or read book Bioresorbable Scaffolds written by Yoshinobu Onuma and published by CRC Press. This book was released on 2017-10-02 with total page 533 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on the coronary bioresorbable scaffold, a new interventional treatment for coronary artery disease, differentiated from a permanent metallic stent. The book provides an overview of the technology including non-clinical studies and clinical evidences in order to help clinicians understand the appropriate application of the technology and the optimal techniques of implantation. It covers the basics of bioresorbable scaffolds; bench test results; preclinical studies; clinical evidences; and tips and tricks of implantation.

Advances in Quantitative Coronary Arteriography

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Publisher : Springer Science & Business Media
ISBN 13 : 940111854X
Total Pages : 617 pages
Book Rating : 4.4/5 (11 download)

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Book Synopsis Advances in Quantitative Coronary Arteriography by : Johan H. C. Reiber

Download or read book Advances in Quantitative Coronary Arteriography written by Johan H. C. Reiber and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 617 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this fourth book in the series on quantitative coronary arteriography (QCA) with the earlier three volumes published in 1986, 1988 and 1991, the latest developments in this exciting field are covered. Both the methodolog ical and clinical application aspects of these advances are presented in a comprehensive manner in a total of 37 chapters by world renowned experts. The book is subdivided into a total of eight parts, beginning with the more methodological issues, such as QCA and other modalities (3 chapters), cine film versus digital arteriography (3 chapters), quality control in QCA (4 chapters), and coronary blood flow and flow reserve (3 chapters). Since QCA has been well established as the technique for the assessment of regression and progression in atherosclerotic disease, and of restenosis after recanaliz ation procedures, major clinical trials in both groups are described extensively by their principal investigators in a total of 11 chapters. In addition, the QCA results after the application of various recanalization techniques are presented in another eight chapters. In the last part the experiences with various intracoronary prostheses with the emphasis on QCA are discussed in five chapters. This large increase in application oriented chapters means that QCA is well alive and gaining momentum. Although the accuracy and precision of the analytical methods steadily improve with the increasing complexity of the algorithms, there is still always the human factor involved in these processes in terms of frame selection, segment definition, etc.

National Library of Medicine Current Catalog

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Publisher :
ISBN 13 :
Total Pages : 1332 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis National Library of Medicine Current Catalog by : National Library of Medicine (U.S.)

Download or read book National Library of Medicine Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on 1992 with total page 1332 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cardiac CT Imaging

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Publisher : Springer
ISBN 13 : 3319282190
Total Pages : 565 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis Cardiac CT Imaging by : Matthew J. Budoff

Download or read book Cardiac CT Imaging written by Matthew J. Budoff and published by Springer. This book was released on 2016-03-29 with total page 565 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book collates all the current knowledge of cardiac CT and presents it in a clinically relevant and practical textbook format appropriate for both cardiologists and radiologists. The images have been supplied by an experienced set of contributing authors and represent the full spectrum of cardiac CT. The field of Cardiovascular CT has experienced continued rapid evolution due to: 1) advances in technology, 2) expanded spectrum of cardiovascular applications and 3) significant growth in published data including large prospective multicenter studies. As increasing numbers have access to cardiac CT scanners, this book provides all the relevant information on this modality. This is an extensive update of the previous edition bringing the reader up-to-date with the immense amount of updated content in the discipline.