Repeated Measurements and Cross-Over Designs

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 1118709306
Total Pages : 272 pages
Book Rating : 4.1/5 (187 download)

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Book Synopsis Repeated Measurements and Cross-Over Designs by : Damaraju Raghavarao

Download or read book Repeated Measurements and Cross-Over Designs written by Damaraju Raghavarao and published by John Wiley & Sons. This book was released on 2014-03-25 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: An introduction to state-of-the-art experimental design approaches to better understand and interpret repeated measurement data in cross-over designs. Repeated Measurements and Cross-Over Designs: Features the close tie between the design, analysis, and presentation of results Presents principles and rules that apply very generally to most areas of research, such as clinical trials, agricultural investigations, industrial procedures, quality control procedures, and epidemiological studies Includes many practical examples, such as PK/PD studies in the pharmaceutical industry, k-sample and one sample repeated measurement designs for psychological studies, and residual effects of different treatments in controlling conditions such as asthma, blood pressure, and diabetes. Utilizes SAS(R) software to draw necessary inferences. All SAS output and data sets are available via the book's related website. This book is ideal for a broad audience including statisticians in pre-clinical research, researchers in psychology, sociology, politics, marketing, and engineering.

Repeated Measurements and Cross-Over Designs

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 111870925X
Total Pages : 272 pages
Book Rating : 4.1/5 (187 download)

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Book Synopsis Repeated Measurements and Cross-Over Designs by : Damaraju Raghavarao

Download or read book Repeated Measurements and Cross-Over Designs written by Damaraju Raghavarao and published by John Wiley & Sons. This book was released on 2014-04-14 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: An introduction to state-of-the-art experimental design approaches to better understand and interpret repeated measurement data in cross-over designs. Repeated Measurements and Cross-Over Designs: Features the close tie between the design, analysis, and presentation of results Presents principles and rules that apply very generally to most areas of research, such as clinical trials, agricultural investigations, industrial procedures, quality control procedures, and epidemiological studies Includes many practical examples, such as PK/PD studies in the pharmaceutical industry, k-sample and one sample repeated measurement designs for psychological studies, and residual effects of different treatments in controlling conditions such as asthma, blood pressure, and diabetes. Utilizes SAS(R) software to draw necessary inferences. All SAS output and data sets are available via the book's related website. This book is ideal for a broad audience including statisticians in pre-clinical research, researchers in psychology, sociology, politics, marketing, and engineering.

Cross-over Trials in Clinical Research

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 0470854588
Total Pages : 364 pages
Book Rating : 4.4/5 (78 download)

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Book Synopsis Cross-over Trials in Clinical Research by : Stephen S. Senn

Download or read book Cross-over Trials in Clinical Research written by Stephen S. Senn and published by John Wiley & Sons. This book was released on 2003-07-25 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cross-over trials are an important class of design used in the pharmaceutical industry and medical research, and their use continues to grow. Cross-over Trials in Clinical Research, Second Edition has been fully updated to include the latest methodology used in the design and analysis of cross-over trials. It includes more background material, greater coverage of important statistical techniques, including Bayesian methods, and discussion of analysis using a number of statistical software packages. * Comprehensive coverage of the design and analysis of cross-over trials. * Each technique is carefully explained and the mathematics is kept to a minimum. * Features many real and original examples, taken from the author's vast experience. * Includes discussion of analysis using SAS, S-Plus and, GenStat, StatXact and Excel. * Written in a style suitable for statisticians and physicians alike. * Computer programs to accompany the examples in the book can be downloaded from the Web Primarily aimed at statisticians and researchers working in the pharmaceutical industry, the book will also appeal to physicians involved in clinical research and students of medical statistics.

Principles and Practice of Clinical Trials

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Author :
Publisher : Springer Nature
ISBN 13 : 3319526367
Total Pages : 2573 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis Principles and Practice of Clinical Trials by : Steven Piantadosi

Download or read book Principles and Practice of Clinical Trials written by Steven Piantadosi and published by Springer Nature. This book was released on 2022-07-19 with total page 2573 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a comprehensive major reference work for our SpringerReference program covering clinical trials. Although the core of the Work will focus on the design, analysis, and interpretation of scientific data from clinical trials, a broad spectrum of clinical trial application areas will be covered in detail. This is an important time to develop such a Work, as drug safety and efficacy emphasizes the Clinical Trials process. Because of an immense and growing international disease burden, pharmaceutical and biotechnology companies continue to develop new drugs. Clinical trials have also become extremely globalized in the past 15 years, with over 225,000 international trials ongoing at this point in time. Principles in Practice of Clinical Trials is truly an interdisciplinary that will be divided into the following areas: 1) Clinical Trials Basic Perspectives 2) Regulation and Oversight 3) Basic Trial Designs 4) Advanced Trial Designs 5) Analysis 6) Trial Publication 7) Topics Related Specific Populations and Legal Aspects of Clinical Trials The Work is designed to be comprised of 175 chapters and approximately 2500 pages. The Work will be oriented like many of our SpringerReference Handbooks, presenting detailed and comprehensive expository chapters on broad subjects. The Editors are major figures in the field of clinical trials, and both have written textbooks on the topic. There will also be a slate of 7-8 renowned associate editors that will edit individual sections of the Reference.

Repeated Measures Design for Empirical Researchers

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 1119052718
Total Pages : 280 pages
Book Rating : 4.1/5 (19 download)

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Book Synopsis Repeated Measures Design for Empirical Researchers by : J. P. Verma

Download or read book Repeated Measures Design for Empirical Researchers written by J. P. Verma and published by John Wiley & Sons. This book was released on 2015-08-31 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduces the applications of repeated measures design processes with the popular IBM® SPSS® software Repeated Measures Design for Empirical Researchers presents comprehensive coverage of the formation of research questions and the analysis of repeated measures using IBM SPSS and also includes the solutions necessary for understanding situations where the designs can be used. In addition to explaining the computation involved in each design, the book presents a unique discussion on how to conceptualize research problems as well as identify appropriate repeated measures designs for research purposes. Featuring practical examples from a multitude of domains including psychology, the social sciences, management, and sports science, the book helps readers better understand the associated theories and methodologies of repeated measures design processes. The book covers various fundamental concepts involved in the design of experiments, basic statistical designs, computational details, differentiating independent and repeated measures designs, and testing assumptions. Along with an introduction to IBM SPSS software, Repeated Measures Design for Empirical Researchers includes: A discussion of the popular repeated measures designs frequently used by researchers, such as one-way repeated measures ANOVA, two-way repeated measures design, two-way mixed design, and mixed design with two-way MANOVA Coverage of sample size determination for the successful implementation of designing and analyzing a repeated measures study A step-by-step guide to analyzing the data obtained with real-world examples throughout to illustrate the underlying advantages and assumptions A companion website with supplementary IBM SPSS data sets and programming solutions as well as additional case studies Repeated Measures Design for Empirical Researchers is a useful textbook for graduate- and PhD-level students majoring in biostatistics, the social sciences, psychology, medicine, management, sports, physical education, and health. The book is also an excellent reference for professionals interested in experimental designs and statistical sciences as well as statistical consultants and practitioners from other fields including biological, medical, agricultural, and horticultural sciences. J. P. Verma, PhD, is Professor of Statistics and Director of the Center for Advanced Studies at Lakshmibai National Institute of Physical Education, India. Professor Verma is an active researcher in sports modeling and data analysis and has conducted many workshops on research methodology, research designs, multivariate analysis, statistical modeling, and data analysis for students of management, physical education, social science, and economics. He is the author of Statistics for Exercise Science and Health with Microsoft® Office Excel®, also published by Wiley.

Design and Analysis of Cross-Over Trials, Second Edition

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Author :
Publisher : CRC Press
ISBN 13 : 1420036092
Total Pages : 390 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Design and Analysis of Cross-Over Trials, Second Edition by : Byron Jones

Download or read book Design and Analysis of Cross-Over Trials, Second Edition written by Byron Jones and published by CRC Press. This book was released on 2003-03-12 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first edition of Design and Analysis of Cross-Over Trials quickly became the standard reference on the subject and has remained so for more than 12 years. In that time, however, the use of cross-over trials has grown rapidly, particularly in the pharmaceutical arena, and researchers have made a number of advances in both the theory and methods applicable to these trials. Completely revised and updated, the long-awaited second edition of this classic text retains its predecessor's careful balance of theory and practice while incorporating new approaches, more data sets, and a broader scope. Enhancements in the second edition include: A new chapter on bioequivalence Recently developed methods for analyzing longitudinal continuous and categorical data Real-world examples using the SAS system A comprehensive catalog of designs, datasets, and SAS programs available on a companion Web site at www.crcpress.com The authors' exposition gives a clear, unified account of the design and analysis of cross-over trials from a statistical perspective along with their methodological underpinnings. With SAS programs and a thorough treatment of design issues, Design and Analysis of Cross-Over Trials, Second Edition sets a new standard for texts in this area and undoubtedly will be of direct practical value for years to come.

Small Clinical Trials

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Publisher : National Academies Press
ISBN 13 : 0309171148
Total Pages : 221 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Small Clinical Trials by : Institute of Medicine

Download or read book Small Clinical Trials written by Institute of Medicine and published by National Academies Press. This book was released on 2001-01-01 with total page 221 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical trials are used to elucidate the most appropriate preventive, diagnostic, or treatment options for individuals with a given medical condition. Perhaps the most essential feature of a clinical trial is that it aims to use results based on a limited sample of research participants to see if the intervention is safe and effective or if it is comparable to a comparison treatment. Sample size is a crucial component of any clinical trial. A trial with a small number of research participants is more prone to variability and carries a considerable risk of failing to demonstrate the effectiveness of a given intervention when one really is present. This may occur in phase I (safety and pharmacologic profiles), II (pilot efficacy evaluation), and III (extensive assessment of safety and efficacy) trials. Although phase I and II studies may have smaller sample sizes, they usually have adequate statistical power, which is the committee's definition of a "large" trial. Sometimes a trial with eight participants may have adequate statistical power, statistical power being the probability of rejecting the null hypothesis when the hypothesis is false. Small Clinical Trials assesses the current methodologies and the appropriate situations for the conduct of clinical trials with small sample sizes. This report assesses the published literature on various strategies such as (1) meta-analysis to combine disparate information from several studies including Bayesian techniques as in the confidence profile method and (2) other alternatives such as assessing therapeutic results in a single treated population (e.g., astronauts) by sequentially measuring whether the intervention is falling above or below a preestablished probability outcome range and meeting predesigned specifications as opposed to incremental improvement.

Analysis of Repeated Measures

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Author :
Publisher : Routledge
ISBN 13 : 1351466631
Total Pages : 190 pages
Book Rating : 4.3/5 (514 download)

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Book Synopsis Analysis of Repeated Measures by : Martin J. Crowder

Download or read book Analysis of Repeated Measures written by Martin J. Crowder and published by Routledge. This book was released on 2017-10-24 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt: Repeated measures data arise when the same characteristic is measured on each case or subject at several times or under several conditions. There is a multitude of techniques available for analysing such data and in the past this has led to some confusion. This book describes the whole spectrum of approaches, beginning with very simple and crude methods, working through intermediate techniques commonly used by consultant statisticians, and concluding with more recent and advanced methods. Those covered include multiple testing, response feature analysis, univariate analysis of variance approaches, multivariate analysis of variance approaches, regression models, two-stage line models, approaches to categorical data and techniques for analysing crossover designs. The theory is illustrated with examples, using real data brought to the authors during their work as statistical consultants.

Design and Analysis of Clinical Experiments

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Publisher : John Wiley & Sons
ISBN 13 : 1118031172
Total Pages : 458 pages
Book Rating : 4.1/5 (18 download)

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Book Synopsis Design and Analysis of Clinical Experiments by : Joseph L. Fleiss

Download or read book Design and Analysis of Clinical Experiments written by Joseph L. Fleiss and published by John Wiley & Sons. This book was released on 2011-01-25 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt: First published in 1986, this unique reference to clinical experimentation remains just as relevant today. Focusing on the principles of design and analysis of studies on human subjects, this book utilizes and integrates both modern and classical designs. Coverage is limited to experimental comparisons of treatments, or in other words, clinical studies in which treatments are assigned to subjects at random.

Repeated Measures Design with Generalized Linear Mixed Models for Randomized Controlled Trials

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Author :
Publisher : CRC Press
ISBN 13 : 1498747906
Total Pages : 376 pages
Book Rating : 4.4/5 (987 download)

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Book Synopsis Repeated Measures Design with Generalized Linear Mixed Models for Randomized Controlled Trials by : Toshiro Tango

Download or read book Repeated Measures Design with Generalized Linear Mixed Models for Randomized Controlled Trials written by Toshiro Tango and published by CRC Press. This book was released on 2017-09-14 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: Repeated Measures Design with Generalized Linear Mixed Models for Randomized Controlled Trials is the first book focused on the application of generalized linear mixed models and its related models in the statistical design and analysis of repeated measures from randomized controlled trials. The author introduces a new repeated measures design called S:T design combined with mixed models as a practical and useful framework of parallel group RCT design because of easy handling of missing data and sample size reduction. The book emphasizes practical, rather than theoretical, aspects of statistical analyses and the interpretation of results. It includes chapters in which the author describes some old-fashioned analysis designs that have been in the literature and compares the results with those obtained from the corresponding mixed models. The book will be of interest to biostatisticians, researchers, and graduate students in the medical and health sciences who are involved in clinical trials. Author Website:Data sets and programs used in the book are available at http://www.medstat.jp/downloadrepeatedcrc.html

Linear and Nonlinear Models for the Analysis of Repeated Measurements

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Publisher : CRC Press
ISBN 13 : 9780824782481
Total Pages : 590 pages
Book Rating : 4.7/5 (824 download)

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Book Synopsis Linear and Nonlinear Models for the Analysis of Repeated Measurements by : Edward Vonesh

Download or read book Linear and Nonlinear Models for the Analysis of Repeated Measurements written by Edward Vonesh and published by CRC Press. This book was released on 1996-11-01 with total page 590 pages. Available in PDF, EPUB and Kindle. Book excerpt: Integrates the latest theory, methodology and applications related to the design and analysis of repeated measurement. The text covers a broad range of topics, including the analysis of repeated measures design, general crossover designs, and linear and nonlinear regression models. It also contains a 3.5 IBM compatible disk, with software to implement immediately the techniques.

Analysis of High Dimensional Repeated Measures Designs

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Publisher : Cuvillier Verlag
ISBN 13 : 3867277346
Total Pages : 115 pages
Book Rating : 4.8/5 (672 download)

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Book Synopsis Analysis of High Dimensional Repeated Measures Designs by : Muhammad Rauf Ahmad

Download or read book Analysis of High Dimensional Repeated Measures Designs written by Muhammad Rauf Ahmad and published by Cuvillier Verlag. This book was released on 2008 with total page 115 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Encyclopedia of Research Design

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Publisher : SAGE
ISBN 13 : 1412961270
Total Pages : 1779 pages
Book Rating : 4.4/5 (129 download)

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Book Synopsis Encyclopedia of Research Design by : Neil J. Salkind

Download or read book Encyclopedia of Research Design written by Neil J. Salkind and published by SAGE. This book was released on 2010-06-22 with total page 1779 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Comprising more than 500 entries, the Encyclopedia of Research Design explains how to make decisions about research design, undertake research projects in an ethical manner, interpret and draw valid inferences from data, and evaluate experiment design strategies and results. Two additional features carry this encyclopedia far above other works in the field: bibliographic entries devoted to significant articles in the history of research design and reviews of contemporary tools, such as software and statistical procedures, used to analyze results. It covers the spectrum of research design strategies, from material presented in introductory classes to topics necessary in graduate research; it addresses cross- and multidisciplinary research needs, with many examples drawn from the social and behavioral sciences, neurosciences, and biomedical and life sciences; it provides summaries of advantages and disadvantages of often-used strategies; and it uses hundreds of sample tables, figures, and equations based on real-life cases."--Publisher's description.

Longitudinal Data Analysis

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Publisher : CRC Press
ISBN 13 : 142001157X
Total Pages : 633 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Longitudinal Data Analysis by : Garrett Fitzmaurice

Download or read book Longitudinal Data Analysis written by Garrett Fitzmaurice and published by CRC Press. This book was released on 2008-08-11 with total page 633 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although many books currently available describe statistical models and methods for analyzing longitudinal data, they do not highlight connections between various research threads in the statistical literature. Responding to this void, Longitudinal Data Analysis provides a clear, comprehensive, and unified overview of state-of-the-art theory

The SAGE Encyclopedia of Communication Research Methods

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Publisher : SAGE Publications
ISBN 13 : 1483381420
Total Pages : 2013 pages
Book Rating : 4.4/5 (833 download)

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Book Synopsis The SAGE Encyclopedia of Communication Research Methods by : Mike Allen

Download or read book The SAGE Encyclopedia of Communication Research Methods written by Mike Allen and published by SAGE Publications. This book was released on 2017-04-11 with total page 2013 pages. Available in PDF, EPUB and Kindle. Book excerpt: Communication research is evolving and changing in a world of online journals, open-access, and new ways of obtaining data and conducting experiments via the Internet. Although there are generic encyclopedias describing basic social science research methodologies in general, until now there has been no comprehensive A-to-Z reference work exploring methods specific to communication and media studies. Our entries, authored by key figures in the field, focus on special considerations when applied specifically to communication research, accompanied by engaging examples from the literature of communication, journalism, and media studies. Entries cover every step of the research process, from the creative development of research topics and questions to literature reviews, selection of best methods (whether quantitative, qualitative, or mixed) for analyzing research results and publishing research findings, whether in traditional media or via new media outlets. In addition to expected entries covering the basics of theories and methods traditionally used in communication research, other entries discuss important trends influencing the future of that research, including contemporary practical issues students will face in communication professions, the influences of globalization on research, use of new recording technologies in fieldwork, and the challenges and opportunities related to studying online multi-media environments. Email, texting, cellphone video, and blogging are shown not only as topics of research but also as means of collecting and analyzing data. Still other entries delve into considerations of accountability, copyright, confidentiality, data ownership and security, privacy, and other aspects of conducting an ethical research program. Features: 652 signed entries are contained in an authoritative work spanning four volumes available in choice of electronic or print formats. Although organized A-to-Z, front matter includes a Reader’s Guide grouping entries thematically to help students interested in a specific aspect of communication research to more easily locate directly related entries. Back matter includes a Chronology of the development of the field of communication research; a Resource Guide to classic books, journals, and associations; a Glossary introducing the terminology of the field; and a detailed Index. Entries conclude with References/Further Readings and Cross-References to related entries to guide students further in their research journeys. The Index, Reader’s Guide themes, and Cross-References combine to provide robust search-and-browse in the e-version.

Optimal Crossover Designs

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Author :
Publisher : World Scientific
ISBN 13 : 9812818421
Total Pages : 238 pages
Book Rating : 4.8/5 (128 download)

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Book Synopsis Optimal Crossover Designs by : Mausumi Bose

Download or read book Optimal Crossover Designs written by Mausumi Bose and published by World Scientific. This book was released on 2009 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph presents a comprehensive and up-to-date account of the developments in optimality aspects of crossover designs. Crossover designs are immensely useful in various areas of human investigation including agriculture, animal nutrition, clinical trials, pharmaceutical studies, biological assays, weather modification experiments, sensory evaluation of food products and learning experiments. Research on the optimality aspects of crossover designs has developed only in the last three decades, and it has now emerged as a potential field for further investigation. This book is the first comprehensive treatise on this subject. It covers optimal crossover designs at length by consolidating vast amounts of material from the literature, and includes many recent and deep results. It is expected that this book will not only provide a one-stop reference for the available results, but also encourage further research in this area of substantial practical relevance.

The SAGE Encyclopedia of Educational Research, Measurement, and Evaluation

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Author :
Publisher : SAGE Publications
ISBN 13 : 1506326145
Total Pages : 1996 pages
Book Rating : 4.5/5 (63 download)

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Book Synopsis The SAGE Encyclopedia of Educational Research, Measurement, and Evaluation by : Bruce B. Frey

Download or read book The SAGE Encyclopedia of Educational Research, Measurement, and Evaluation written by Bruce B. Frey and published by SAGE Publications. This book was released on 2018-01-29 with total page 1996 pages. Available in PDF, EPUB and Kindle. Book excerpt: This encyclopedia is the first major reference guide for students new to the field, covering traditional areas while pointing the way to future developments.