The Molecular Biology of Schizosaccharomyces pombe

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3662103605
Total Pages : 464 pages
Book Rating : 4.6/5 (621 download)

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Book Synopsis The Molecular Biology of Schizosaccharomyces pombe by : Richard Egel

Download or read book The Molecular Biology of Schizosaccharomyces pombe written by Richard Egel and published by Springer Science & Business Media. This book was released on 2013-03-14 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: The fission yeast Schizosaccharomyces pombe is the favoured tool of many productive research groups throughout the world, serving as a useful model for fundamental principles and mechanisms, such as genome organization, differential gene regulation, cell-cycle control, signal transduction, or cellular morphogenesis. This book collates the current state of knowledge derived from molecular studies in this simple eukaryotic microorganism. The entire sequence of its genome has been completed, emphasizing the comparative value and model status of this yeast. The individual chapters, highlighting up-to-date views on prominent aspects of molecular organization, were written by active research scientists, presenting the results of their investigations to other workers in neighbouring fields. This book intends to serve the fission yeast community as a handy source of reference for years to come. It will also be of particular value to the ever-increasing number of researchers starting to look into fission yeast affairs for comparative reasons from other platforms of molecular genetics and cell biology.

Translational Control of Gene Expression

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Publisher : CSHL Press
ISBN 13 : 9780879696184
Total Pages : 1034 pages
Book Rating : 4.6/5 (961 download)

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Book Synopsis Translational Control of Gene Expression by : Nahum Sonenberg

Download or read book Translational Control of Gene Expression written by Nahum Sonenberg and published by CSHL Press. This book was released on 2001 with total page 1034 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the 1996 publication of Translational Control, there has been fresh interest in protein synthesis and recognition of the key role of translation control mechanisms in regulating gene expression. This new monograph updates and expands the scope of the earlier book but it also takes a fresh look at the field. In a new format, the first eight chapters provide broad overviews, while each of the additional twenty-eight has a focus on a research topic of more specific interest. The result is a thoroughly up-to-date account of initiation, elongation, and termination of translation, control mechanisms in development in response to extracellular stimuli, and the effects on the translation machinery of virus infection and disease. This book is essential reading for students entering the field and an invaluable resource for investigators of gene expression and its control.

Fission Yeast

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Publisher :
ISBN 13 : 9781621820819
Total Pages : 0 pages
Book Rating : 4.8/5 (28 download)

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Book Synopsis Fission Yeast by : Iain Hagan

Download or read book Fission Yeast written by Iain Hagan and published by . This book was released on 2016 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fission yeast are unicellular, rod-shaped fungi that divide by medial fission. Studies using fission yeast were instrumental in identifying fundamental mechanisms that govern cell division, differentiation, and epigenetics, to name but a few. Their rapid growth rate, genetic malleability, and similarities to more complex eukaryotes continue to make them excellent subjects for many biochemical, molecular, and cell biological studies. This laboratory manual provides an authoritative collection of core experimental procedures that underpin modern fission yeast research. The contributors describe basic methods for culturing and genetically manipulating fission yeast, synchronization strategies for probing the cell cycle, technologies for assessing proteins, metabolites, and cell wall constituents, imaging methods to visualize subcellular structures and dynamics, and protocols for investigating chromatin and nucleic acid metabolism. Modifications to techniques commonly used in related species (e.g., budding yeast) are noted, as are useful resources for fission yeast researchers, including various databases and repositories. The well-studied fission yeast Schizosaccharomyces pombe is the focus throughout, but the emerging model S. japonicus-a larger, dimorphic species with several desirable characteristics-is also covered. This manual is an important reference for existing fission yeast laboratories and will serve as an essential start-up guide for those working with fission yeast for the first time.

Stress-Activated Protein Kinases

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Publisher : Springer Science & Business Media
ISBN 13 : 3540755691
Total Pages : 322 pages
Book Rating : 4.5/5 (47 download)

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Book Synopsis Stress-Activated Protein Kinases by : Francesc Posas

Download or read book Stress-Activated Protein Kinases written by Francesc Posas and published by Springer Science & Business Media. This book was released on 2008-01-24 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book leading researchers in the field discuss the state-of-the-art of many aspects of SAPK signaling in various systems from yeast to mammals. These include various chapters on regulatory mechanisms as well as the contribution of the SAPK signaling pathways to processes such as gene expression, metabolism, cell cycle regulation, immune responses and tumorigenesis. Written by international experts, the book will appeal to cell biologists and biochemists.

Molecular Aspects of the Stress Response: Chaperones, Membranes and Networks

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Publisher : Springer Science & Business Media
ISBN 13 : 0387399755
Total Pages : 218 pages
Book Rating : 4.3/5 (873 download)

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Book Synopsis Molecular Aspects of the Stress Response: Chaperones, Membranes and Networks by : Peter Csermely

Download or read book Molecular Aspects of the Stress Response: Chaperones, Membranes and Networks written by Peter Csermely and published by Springer Science & Business Media. This book was released on 2007-08-09 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book makes a novel synthesis of the molecular aspects of the stress response and long term adaptation processes with the system biology approach of biological networks. Authored by an exciting mixture of top experts and young rising stars, it provides a comprehensive summary of the field and identifies future trends.

Molecular Biology of the Fission Yeast

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Author :
Publisher : Elsevier
ISBN 13 : 0323140068
Total Pages : 482 pages
Book Rating : 4.3/5 (231 download)

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Book Synopsis Molecular Biology of the Fission Yeast by :

Download or read book Molecular Biology of the Fission Yeast written by and published by Elsevier. This book was released on 2012-12-02 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: This highly researched yeast, which represents a system used by cell biologists, geneticists and molecular biologists, has been given only minimal coverage in the literature. Its properties make it an excellent organism for DNA and related biotechnology reseach. This book, which is the first attempt to collate existing information in one source, will be an invaluable aid to those initiating projects with this organism.

Retroviral Proteases

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Publisher :
ISBN 13 :
Total Pages : 200 pages
Book Rating : 4.:/5 (51 download)

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Book Synopsis Retroviral Proteases by : Laurence H. Pearl

Download or read book Retroviral Proteases written by Laurence H. Pearl and published by . This book was released on 1990 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume describes the state-of-the-art of our understanding of the structure and function of retroviral proteases, and their substrates, the viral polyproteins, described by the leading workers in the field. The contributions range from detailed biochemical and structural characterisation of several retroviral proteases including that from HIV-1, through the analysis of the proteolytic processing of the viral polyproteins, to the structure of the viral capsids formed by the action of the protease, and is essential reading for anyone interested in the molecular biology of AIDS.

Photochemistry

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Publisher : Royal Society of Chemistry
ISBN 13 : 183916526X
Total Pages : 507 pages
Book Rating : 4.8/5 (391 download)

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Book Synopsis Photochemistry by : Stefano Crespi

Download or read book Photochemistry written by Stefano Crespi and published by Royal Society of Chemistry. This book was released on 2021-09-20 with total page 507 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing critical analysis of emerging and well-established topics, this book is essential reading for anyone wanting to keep up to date with the literature on photochemistry and its applications. Volume 49 combines reviews on the latest advances in photochemical research with specific highlights in the field. The first section includes periodical reports of the recent literature on physical and inorganic aspects, including reviews of the molecules employed as dyes in art, light induced reactions in cryogenic matrices, photobiological systems studied by time-resolved infrared spectroscopy and photophysics, and photochemistry of transition metal complexes. This selection is completed by reviews of the literature on solar photocatalysis for water decontamination and disinfection and for water splitting/hydrogen production. Coverage continues in the second part with highlighted topics, from the use of aromatic carbonyls as photocatalysts and photoinitiators in synthesis, photoinduced and photocatalysed decarboxylation reactions, development of dye-sensitized solar cells, design of luminescent water-soluble systems, and applications of plasmonic nanoparticles. This volume also includes a third section entitled ‘SPR Lectures on Photochemistry’, where leading scientists in photochemistry provide examples to introduce a photochemical topic to academic readers, offering precious assistance to students in this field.

Regulation of G1 Phase Progression

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Publisher : Springer Science & Business Media
ISBN 13 : 9780306478314
Total Pages : 284 pages
Book Rating : 4.4/5 (783 download)

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Book Synopsis Regulation of G1 Phase Progression by : Johannes Boonstra

Download or read book Regulation of G1 Phase Progression written by Johannes Boonstra and published by Springer Science & Business Media. This book was released on 2003-09-30 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this contribution, several specialists describe the current knowledge on the molecular networks that regulate cell cycle progression, with an emphasis on the G1 phase of the cell cycle. The first part of Regulation of G1 Phase Progression is concerned with the individual molecules that form the network, including cyclins, cyclin-dependent kinases, inhibitors of these kinases and retinoblastoma and p53. The second section describes the signaling cascades by which external factors influence the cell cycle network, including mitogens, the extracellular matrix, nutrients and oxygen radicals. The last section describes the effects of specific external conditions on cell cycle progression and are presented such as serum starvation and subsequent re-addition and stress conditions (heat, osmolarity). The final two chapters describe the relation between cell cycle progression with cell differentiation and with apoptosis.

Cell Cycle Checkpoint Control Protocols

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Publisher : Humana Press
ISBN 13 : 9781588291158
Total Pages : 376 pages
Book Rating : 4.2/5 (911 download)

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Book Synopsis Cell Cycle Checkpoint Control Protocols by : Howard B. Lieberman

Download or read book Cell Cycle Checkpoint Control Protocols written by Howard B. Lieberman and published by Humana Press. This book was released on 2003-11-14 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of cell cycle regulation is based on the observation that the life cycle of a cell progresses through several distinct phases, G1, M, S, and G2, occurring in a well-defined temporal order. Details of the mechanisms involved are rapidly emerging and appear extraordinarily complex. Furthermore, not only is the order of the phases important, but in normal eukaryotic cells one phase will not begin unless the prior phase is completed successfully. Che- point control mechanisms are essentially surveillance systems that monitor the events in each phase, and assure that the cell does not progress prematurely to the next phase. If conditions are such that the cell is not ready to progress—for example, because of incomplete DNA replication in S or DNA damage that may interfere with chromosome segregation in M—a transient delay in cell cycle progression will occur. Once the inducing event is properly handled— for example, DNA replication is no longer blocked or damaged DNA is repaired—cell cycle progression continues. Checkpoint controls have recently been the focus of intense study by investigators interested in mechanisms that regulate the cell cycle. Furthermore, the relationship between checkpoint c- trol and carcinogenesis has additionally enhanced interest in these cell cycle regulatory pathways. It is clear that cancer cells often lack these checkpoints and exhibit genomic instability as a result. Moreover, several tumor suppressor genes participate in checkpoint control, and alterations in these genes are as- ciated with genomic instability as well as the development of cancer.

DNA Replication

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Publisher : Humana
ISBN 13 : 9781493955916
Total Pages : 0 pages
Book Rating : 4.9/5 (559 download)

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Book Synopsis DNA Replication by : Sonya Vengrova

Download or read book DNA Replication written by Sonya Vengrova and published by Humana. This book was released on 2016-10-29 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Updated and revised, this thorough volume covers a range of methods focusing on systems, including mammalian, yeast, bacterial and archaeal. This second edition of DNA Replication: Methods and Protocols describes approaches to analyze whole genomes to single molecules, as well as both in vivo and in vitro experiments. As a volume in the highly successful Methods in Molecular Biology series, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, DNA Replication: Methods and Protocols, Second Edition provides a collections of methods intended for newcomers to this research field and for established laboratories.

Genetic Polymorphisms

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Publisher : BoD – Books on Demand
ISBN 13 : 9535135155
Total Pages : 282 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Genetic Polymorphisms by : Narasimha Reddy Parine

Download or read book Genetic Polymorphisms written by Narasimha Reddy Parine and published by BoD – Books on Demand. This book was released on 2017-09-06 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: The objective of this Genetic Polymorphisms book is to rehighlight and provide few updates on the role of genetic polymorphisms in medicine and agriculture, which void emerging opinion on "full death" of genetic polymorphisms as useful genetic markers. Chapters presented here demonstrate the future benefit of SNPs in many genetic studies as well as prognosis disease and diagnosis.

Peroxiredoxin Systems

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Publisher : Springer Science & Business Media
ISBN 13 : 1402060505
Total Pages : 408 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Peroxiredoxin Systems by : Leopold Flohé

Download or read book Peroxiredoxin Systems written by Leopold Flohé and published by Springer Science & Business Media. This book was released on 2007-09-05 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains a broad survey on the peroxiredoxins. It involves almost all groups that contributed significant insights into the emerging field. Coverage discusses the diverse biological roles of the new protein family in the context of other antioxidant systems like those based on heme or selenium catalysis. In addition, the book highlights related future perspectives.

Viral Gene Therapy

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Publisher :
ISBN 13 : 9789535164388
Total Pages : 464 pages
Book Rating : 4.1/5 (643 download)

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Book Synopsis Viral Gene Therapy by : Ke Xu

Download or read book Viral Gene Therapy written by Ke Xu and published by . This book was released on 2011 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: The development of technologies that allow targeting of specific cells has progressed substantially in recent years for several types of vectors, particularly viral vectors, which have been used in 70% of gene therapy clinical trials. Particular viruses have been selected as gene delivery vehicles because of their capacities to carry foreign genes and their ability to efficiently deliver these genes associated with efficient gene expression. This book is designed to present the most recent advances in viral gene therapy.

Mechanisms in Transcriptional Regulation

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Publisher : John Wiley & Sons
ISBN 13 : 1444300458
Total Pages : 248 pages
Book Rating : 4.4/5 (443 download)

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Book Synopsis Mechanisms in Transcriptional Regulation by : Albert J. Courey

Download or read book Mechanisms in Transcriptional Regulation written by Albert J. Courey and published by John Wiley & Sons. This book was released on 2009-01-22 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mechanisms in Transcriptional Regulation provides a concisediscussion of the fundamental concepts in transcription and itsregulation. Covers RNA polymerases, transcriptional machinery, mechanismsof transcriptional activation, the histone code hypothesis, theepigenetic control of transcription, and combinatorial control insignaling and development Features over 80 figures available to download online Chapters include comprehensive reading lists, boxeshighlighting theoretical concepts and experimental methods andproblems designed to build and test understanding

Cell Cycle Regulation

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Author :
Publisher : Results and Problems in Cell Differentiation
ISBN 13 :
Total Pages : 400 pages
Book Rating : 4.X/5 (3 download)

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Book Synopsis Cell Cycle Regulation by : Philipp Kaldis

Download or read book Cell Cycle Regulation written by Philipp Kaldis and published by Results and Problems in Cell Differentiation. This book was released on 2006-06-26 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a state-of-the-art summary of the latest achievements in cell cycle control research with an outlook on the effect of these findings on cancer research. The chapters are written by internationally leading experts in the field. They provide an updated view on how the cell cycle is regulated in vivo, and about the involvement of cell cycle regulators in cancer.

Epigenetic Mechanisms of Gene Regulation

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Publisher :
ISBN 13 :
Total Pages : 716 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Epigenetic Mechanisms of Gene Regulation by : Vincenzo E. A. Russo

Download or read book Epigenetic Mechanisms of Gene Regulation written by Vincenzo E. A. Russo and published by . This book was released on 1996 with total page 716 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many inheritable changes in gene function are not explained by changes in the DNA sequence. Such epigenetic mechanisms are known to influence gene function in most complex organisms and include effects such as transposon function, chromosome imprinting, yeast mating type switching and telomeric silencing. In recent years, epigenetic effects have become a major focus of research activity. This monograph, edited by three well-known biologists from different specialties, is the first to review and synthesize what is known about these effects across all species, particularly from a molecular perspective, and will be of interest to everyone in the fields of molecular biology and genetics.