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Author : Gary Maynard Soenen
Publisher :
ISBN 13 :
Total Pages : 114 pages
Book Rating : 4.:/5 (73 download)
Download or read book Regional Gastric Mucosal Blood Flow in Man written by Gary Maynard Soenen and published by . This book was released on 1990 with total page 114 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Peter R. Kvietys
Publisher : Morgan & Claypool Publishers
ISBN 13 : 1615041176
Total Pages : 127 pages
Book Rating : 4.6/5 (15 download)
Download or read book The Gastrointestinal Circulation written by Peter R. Kvietys and published by Morgan & Claypool Publishers. This book was released on 2010 with total page 127 pages. Available in PDF, EPUB and Kindle. Book excerpt: The microcirculation of the gastrointestinal tract is under the control of both myogenic and metabolic regulatory systems. The myogenic mechanism contributes to basal vascular tone and the regulation of transmural pressure, while the metabolic mechanism is responsible for maintaining an appropriate balance between O2 demand and O2 delivery. In the postprandial state, hydrolytic products of food digestion elicit a hyperemia, which serves to meet the increased O2 demand of nutrient assimilation. Metabolically linked factors (e.g., tissue pO2, adenosine) are primarily responsible for this functional hyperemia. The fenestrated capillaries of the gastrointestinal mucosa are relatively permeable to small hydrolytic products of food digestion (e.g., glucose), yet restrict the transcapillary movement of larger molecules (e.g., albumin). This allows for the absorption of hydrolytic products of food digestion without compromising the oncotic pressure gradient governing transcapillary fluid movement and edema formation. The gastrointestinal microcirculation is also an important component of the mucosal defense system whose function is to prevent (and rapidly repair) inadvertent epithelial injury by potentially noxious constituents of chyme. Two pathological conditions in which the gastrointestinal circulation plays an important role are ischemia/reperfusion and chronic portal hypertension. Ischemia/reperfusion results in mucosal edema and disruption of the epithelium due, in part, to an inflammatory response (e.g., increase in capillary permeability to macromolecules and neutrophil infiltration). Chronic portal hypertension results in an increase in gastrointestinal blood flow due to an imbalance in vasodilator and vasoconstrictor influences on the microcirculation. Table of Contents: Introduction / Anatomy / Regulation of Vascular Tone and Oxygenation / Extrinsic Vasoregulation: Neural and Humoral / Postprandial Hyperemia / Transcapillary Solute Exchange / Transcapillary Fluid Exchange / Interaction of Capillary and Interstitial Forces / Gastrointestinal Circulation and Mucosal Defense / Gastrointestinal Circulation and Mucosal Pathology I: Ischemia/Reperfusion / Gastrointestinal Circulation and Mucosal Pathology II: Chronic Portal Hypertension / Summary and Conclusions / References / Author Biography
Author : Timothy S. Gaginella
Publisher : CRC Press
ISBN 13 : 9780849383045
Total Pages : 468 pages
Book Rating : 4.3/5 (83 download)
Download or read book Handbook of Methods in Gastrointestinal Pharmacology written by Timothy S. Gaginella and published by CRC Press. This book was released on 1995-10-20 with total page 468 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gastroenterology has advanced through the development and application of increasingly sophisticated methods to measure changes in gastrointestinal function. Handbook of Methods in Gastrointestinal Pharmacology brings together details on commonly employed approaches in investigative gastroenterology. The book provides comprehensive coverage of methods and techniques used to investigate the mechanism of action of drugs on the GI tract. An integral part of each chapter is the discussion of development of techniques based upon physiologic mechanisms and principles in pharmacology. In vivo and in situ techniques involving whole animals, isolated tissue methodology, the use of single cell systems, and molecular biology approaches are covered. Illustrations provide a clear understanding of methodologies discussed. Emphasis is placed on advantages and disadvantages of each technique in answering specific research questions. Chapters are written by experts experienced in the techniques they discuss; many pioneered one or more widely used methods. The wide variety of topics included make the Handbook of Methods in Gastrointestinal Pharmacology useful to established investigators, research fellows, and graduate students. Additionally, reviewers of grants and manuscripts can use it to clarify questions that arise regarding appropriate use of a technique in a particular setting.
Author : J.L. Rombeau
Publisher : Springer
ISBN 13 : 9783642802263
Total Pages : 399 pages
Book Rating : 4.8/5 (22 download)
Download or read book Gut Dysfunction in Critical Illness written by J.L. Rombeau and published by Springer. This book was released on 2014-08-23 with total page 399 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dysfunction of the gastrointestinal tract in critically ill patients has recently become a focus of intensive research. This book, the first one on this topic, is a comprehensive overview of what is currently known about the role of the gut in patients requiring intensive care. The definitions and pathogenesis of intestinal dysfunction are critically evaluated. Currently available and potential new ways to monitor intestinal function in the intensive care setting are presented. Emphasis has been placed on the evaluation of therapeutic strategies in the prevention and treatment of gut dysfunction. Options for monitoring and treating gut dysfunction in critically ill patients are rapidly evolving. This volume provides state-of-the-art information for both clinicians and clinical researchers.
Author : Gustavo S. Oderich
Publisher : Springer
ISBN 13 : 1493918478
Total Pages : 463 pages
Book Rating : 4.4/5 (939 download)
Download or read book Mesenteric Vascular Disease written by Gustavo S. Oderich and published by Springer. This book was released on 2014-11-20 with total page 463 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book represents the first comprehensive textbook devoted to the standard of care, current guidelines and innovations in the field of mesenteric vascular disease. The book reviews imaging modalities, diagnostic work up, physiologic tests, traditional open surgical techniques and novel endovascular approaches. Technical aspects of both open surgical and endovascular techniques are provided by experts in the field, with illustrations and photographs of key steps for each type of procedure. Results of epidemiologic studies and national databases are summarized, as well as large institutional experiences. An evidence-based approach is used for recommendations regarding best therapies. Diagnostic approaches including imaging and novel physiologic tests, including gastric tonometry and oxygen light spectroscopy are covered. Mesenteric Vascular Disease: Current Therapy will serve as a very useful resource for clinicians, surgeons, interventionalists, gastroenterologists and researchers dealing with and interested in mesenteric vascular diseases.
Author : John Barker
Publisher : Routledge
ISBN 13 : 0429523432
Total Pages : 513 pages
Book Rating : 4.4/5 (295 download)
Download or read book Clinically Applied Microcirculation Research written by John Barker and published by Routledge. This book was released on 2019-06-04 with total page 513 pages. Available in PDF, EPUB and Kindle. Book excerpt: First published in 1995: Clinically Applied Microcirculation Research combines state-of-the-art microcirculation technology with present and potential applications in clinical medicine. This comprehensive guide unites the expertise of clinicians and basic researchers from around the world. Many of the chapters are authored by scientist/physician teams. The book provides a broad overview of how microcirculation is involved in clinical research. This is also a valuable reference source for both the history of and latest developments in microcirculation research.
Author : Michael R. Pinsky
Publisher : Springer Science & Business Media
ISBN 13 : 3540269002
Total Pages : 414 pages
Book Rating : 4.5/5 (42 download)
Download or read book Functional Hemodynamic Monitoring written by Michael R. Pinsky and published by Springer Science & Business Media. This book was released on 2005-08-11 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the newest volume in the softcover series "Update in Intensive Care Medicine". It takes a novel, practical approach to analyzing hemodynamic monitoring, focusing on the patient and outcomes based on disease, treatment options and relevance of monitoring to direct patient care. It will rapidly become a classic in the approach to patient monitoring and management during critical illness.
Author : Rainer Greger
Publisher : Springer Science & Business Media
ISBN 13 : 3642609465
Total Pages : 2478 pages
Book Rating : 4.6/5 (426 download)
Download or read book Comprehensive Human Physiology written by Rainer Greger and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 2478 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive Human Physiology is a significantly important publication on physiology, presenting state-of-the-art knowledge about both the molecular mechanisms and the integrative regulation of body functions. This is the first time that such a broad range of perspectives on physiology have been combined to provide a unified overview of the field. This groundbreaking two-volume set reveals human physiology to be a highly dynamic science rooted in the ever-continuing process of learning more about life. Each chapter contains a wealth of original data, clear illustrations, and extensive references, making this a valuable and easy-to-use reference. This is the quintessential reference work in the fields of physiology and pathophysiology, essential reading for researchers, lecturers and advanced students.
Author : Tatsuo Togawa
Publisher : CRC Press
ISBN 13 : 9780849376719
Total Pages : 384 pages
Book Rating : 4.3/5 (767 download)
Download or read book Biomedical TRANSDUCERS and INSTRUMENTS written by Tatsuo Togawa and published by CRC Press. This book was released on 1997-05-21 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomedical transducers are essential instruments for acquiring many types of medical and biological data. From the underlying principles to practical applications, this new book provides an easy- to-understand introduction to the various kinds of biomedical transducers. The first comprehensive treatment of this subject in 20 years, the book presents state-of-the-art information including: discussions of biomedical transducers for measurements of pressure, flow, motion, temperature, heat flow, evaporation, biopotential, biomagnetism, and chemical quantities. Chapters are devoted to particular areas of instrumentation needs
Author :
Publisher :
ISBN 13 :
Total Pages : 1160 pages
Book Rating : 4.3/5 (243 download)
Download or read book Cumulated Index Medicus written by and published by . This book was released on 1985 with total page 1160 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : A.P. Shepherd
Publisher : Springer Science & Business Media
ISBN 13 : 1475720831
Total Pages : 404 pages
Book Rating : 4.4/5 (757 download)
Download or read book Laser-Doppler Blood Flowmetry written by A.P. Shepherd and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: The dance along the artery The circulation on the lymph Are figured in the drift of stars. T. S. Eliot Die Methode ist alles. Carl Ludwig In physiology a spirit of finesse is required. Claude Bernard Armed with modern Doppler instrumentation, scientists can now quantify the red blood cell's "dance along the artery" as well as "the drift of stars. " In disciplines of science and medicine ranging from cardiology to astronomy, the Doppler principle now provides invaluable velo city measurements in the microcosm of capillary beds and in the cosmos. The newest appiication of the ubiquitous Doppler principle, laser-Doppler velocimetry, has been used to measure blood ftow in tissue for just a few years, but we perceived that, like most new techniques, the birth of laser-Doppler blood ftowmetry was not easy, nor was it likely to pass through infancy and reach maturity without difficulty. In physiology and medicine, better techniques for measur ing blood ftow are constantly in demand, but they often exhibit an unfortun ate boom-and-bust cyde: widespread acceptance and uncritical use are soon xiii xiv Preface followed by studies delineating the limits of the method's validity. The technique is then abandoned for the next more fashionable one, thus proving Ludwig's dictum that a given method is everything or nothing depending upon whether one can believe the data it yields.
Author : L. Barbara
Publisher : Springer Science & Business Media
ISBN 13 : 9401177694
Total Pages : 239 pages
Book Rating : 4.4/5 (11 download)
Download or read book Bile Acids in Gastroenterology written by L. Barbara and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past 10 years there has been a veritable explosion of knowledge in working in this area are fortunate to meet their bile acid research. Those colleagues from time to time at International Meetings which are often held in attractive parts of the world. The 7th International Symposium on bile acids 'Bile Acids in Gastroenterology' was no exception. It took place in Cortina d'Ampezzo in the heart of the Italian Dolomites, from 17th-20th March 1982. This meeting was organised by a Scientific Committee, with representatives from Italy, the United States and Great Britain, in collaboration with the Italian Society of Gastroenterology. The format of the meeting was somewhat different from that of previous years. In addition to the free communications (verbal and poster presentations) which characte rise many scientific meetings, there was also an Advanced Postgraduate Course on bile acids given by a distinguished international panel of experts. Their contributions form the basis for this timely volume which should be of interest both to basic scientists and to clinical investigators alike. The editors are indebted to Dr Gian Germano Giuliani, Gipharmex SpA, Milano, whose generous support made the meeting possible. They also thank Mr P. M. Lister, Managing Editor, MTP Press Limited and Mrs Veronica Cesari, Italian Society of Gastroenterology for help with the publication of these proceedings. R. Herman Dowling ix 1 Liquid-solid extraction, lipophilic gel chromatography and capillary column gas chromatography in the analysis of bile acids from biological samples K. D. R.
Author : F. Holle
Publisher : Springer Science & Business Media
ISBN 13 : 364265889X
Total Pages : 432 pages
Book Rating : 4.6/5 (426 download)
Download or read book Vagotomy written by F. Holle and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph is a summary of observations collected over the past ten years on vagal denervation of the stomach and the functional pathology of the vagotomized stomach. It is primarily a continuation of the work we (Holle and Heinrich, 1954) began with fundectomy - the prototype of proximal dener vation of the stomach. This was the starting point for the develop ment of selective proximal vagotomy (SPV). Between 1961 and 1964 the SPY technique was developed to the extent that it could be applied clinically from January 1,1964. Like most clinical innovations, the development took place in several stages. A report on the first 235 surgical cases (1961-1967) appeared in 1968 in F. Holle's Special Surgery of the Stomach, pp. 508-509, and in 1969 in Surgery of the Stomach and Duodenum by Harkins and Nyhus, 2nd edition, pp. 629-634. Since that time it has been possible to demonstrate on the basis of 1200 operated cases as well as animal experiments that the new technique we introduced represents a successful, nonresecting surgical treatment of gastric and duodenal ulcers. It is important to have a long series of clinical cases from the same source, because it is not until a large number of individual observations have been collected concern ing complications of diagnosis, indications and technique that is it possible to analyse the relationships between them.
Author : Daniel Hollander
Publisher : Springer Science & Business Media
ISBN 13 : 1468456970
Total Pages : 228 pages
Book Rating : 4.4/5 (684 download)
Download or read book Gastric Cytoprotection written by Daniel Hollander and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gastric secretions contain hydrogen ions at a concentration that is more than one million times higher than their intracellular concentration. This phenomenal gradient as well as the demonstrated ability of gastric juice to digest tissues has motivated clinicians and investigators alike to emphasize acid secretion and acid ablation in studying the pathogenesis and therapy of peptic ulcer disease. Conse quently, over the past 150 years, we have made considerable progress in under standing the mechanisms and regulation of acid secretion by the stomach. Not surprisingly, therapy for both peptic disease and mucosal injury has also been predominantly directed at either neutralizing acid or suppressing its production. During the past 10 years, attention has been focused on factors other than acid in the genesis and therapy of ulcer disease. Work done worldwide demon strated that acid hypersecretion is not a common event in peptic ulcer disease. Therefore, we began realizing that factors other than acid secretion may be important in the genesis of ulcer disease or in gastroduodenal mucosal damage. In addition, new physiological information has established that the gas troduodenal mucosa is normally protected by a complex series of events includ ing mucus and bicarbonate secretion, cell renewal, surface mucosal restitution, and preservation of the microvasculature and mucosal proliferative zone.
Author : J. Gordon Betts
Publisher :
ISBN 13 : 9781947172807
Total Pages : 0 pages
Book Rating : 4.1/5 (728 download)
Download or read book Anatomy and Physiology written by J. Gordon Betts and published by . This book was released on 2013-04-25 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Jennifer B. Dressman
Publisher : CRC Press
ISBN 13 : 1420077341
Total Pages : 432 pages
Book Rating : 4.4/5 (2 download)
Download or read book Oral Drug Absorption written by Jennifer B. Dressman and published by CRC Press. This book was released on 2016-04-19 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oral Drug Absorption, Second Edition thoroughly examines the special equipment and methods used to test whether drugs are released adequately when administered orally. The contributors discuss methods for accurately establishing and validating in vitro/in vivo correlations for both MR and IR formulations, as well as alternative approaches for MR an
Author : J.L. Rombeau
Publisher : Springer Science & Business Media
ISBN 13 : 3642802249
Total Pages : 402 pages
Book Rating : 4.6/5 (428 download)
Download or read book Gut Dysfunction in Critical Illness written by J.L. Rombeau and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dysfunction of the gastrointestinal tract in critically ill patients has recently become a focus of intensive research. This book, the first one on this topic, is a comprehensive overview of what is currently known about the role of the gut in patients requiring intensive care. The definitions and pathogenesis of intestinal dysfunction are critically evaluated. Currently available and potential new ways to monitor intestinal function in the intensive care setting are presented. Emphasis has been placed on the evaluation of therapeutic strategies in the prevention and treatment of gut dysfunction. Options for monitoring and treating gut dysfunction in critically ill patients are rapidly evolving. This volume provides state-of-the-art information for both clinicians and clinical researchers.
