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Author : 陳致霖
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (18 download)
Download or read book Reforming Ambient Ionization Mass Spectrometry Platforms Towards High Performance in Situ Molecular Imaging written by 陳致霖 and published by . This book was released on 2018 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Kei Zaitsu
Publisher : Elsevier
ISBN 13 : 0128172215
Total Pages : 292 pages
Book Rating : 4.1/5 (281 download)
Download or read book Ambient Ionization Mass Spectrometry in Life Sciences written by Kei Zaitsu and published by Elsevier. This book was released on 2019-11-06 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ambient Ionization Mass Spectrometry in Life Sciences: Principles and Applications is a systematic introduction to this rapidly expanding area of study. Underlying principles of each technique are explained in detail, along with discussions on their applications across life science disciplines. Ambient ionization has recently emerged as one of the hottest and fastest growing topics in mass spectrometry, hence this book is not just for analysts and researchers who use and study mass spectrometry. This volume would be of interest to anyone who works in or studies analytical chemistry, omics sciences (including metabolomics), pharmacokinetics, forensic science or drug analysis. Covers the most up-to-date techniques, including DART, DCBI, DESI, PESI, PSI, REIMS and laser-based ambient ionization Includes easy-to-understand pros and cons of each ionization technique to aid in decision-making Provides plentiful examples of life science applications
Author : Monica Lin
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (141 download)
Download or read book Advancements in Ambient Ionization and MALDI Mass Spectrometry Imaging Methods and Their Application in Disease Diagnosis and Characterization written by Monica Lin and published by . This book was released on 2023 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Direct analysis using mass spectrometry (MS) techniques provide a powerful approach to investigate the molecular composition and spatial distribution of complex samples with high sensitivity and specificity. In particular, these techniques have been widely applied to achieve rapid molecular analysis of complex clinical samples including native tissue samples and biospecimens. Several types of direct analysis MS techniques have been developed for tissue analysis including a variety of ambient ionization MS techniques and matrix-assisted laser desorption ionization (MALDI) MS. Notably, both approaches are highly capable of performing molecular imaging of endogenous metabolites, lipids, and proteins to characterize tissue samples. Furthermore, through applying ambient ionization and MALDI MS imaging techniques, new insights into disease state can be learned by investigating the correlation between spatially resolved molecular information with histological evaluation in tissue samples. Although several other types of direct analysis MS techniques have been developed, this dissertation focuses on advancements using solvent-based ambient ionization MS (e.g. desorption electrospray ionization (DESI)) and MALDI MS imaging methods for tissue analysis and disease characterization. In Chapter 2, a fundamental and systematic investigation of the affect of solvent properties on molecular extraction processes in solvent-based ambient ionization was performed. In Chapter 3, the performance of DESI MS imaging for the analysis and statistical classification of thyroid fine needle aspiration (FNA) biopsies using different solvents, sources, and high-performance MS systems was evaluated. Next, Chapter 4 describes the development of a sample preparation method for MALDI MS imaging to improve detection of various endogenous proteins by selectively reducing signal from hemoglobin proteins in blood-rich tissues. Lastly, in Chapter 5, various MALDI imaging MS methods were applied to characterize the protein and N-glycan molecular signatures in endometriosis tissues and provide new insights into possible mechanisms of endometriosis development and progression. Collectively, this dissertation provides insights into the fundamental aspects, method developments, and applications of direct analysis MS techniques including solvent-based ambient ionization MS and MALDI MS imaging for tissue analysis. Furthermore, this dissertation showcases the exciting and significant potential of direct analysis MS techniques to solve current challenges in the clinic and provide new insights in healthcare and medicine
Author : Marek Domin
Publisher : Royal Society of Chemistry
ISBN 13 : 1782628029
Total Pages : 529 pages
Book Rating : 4.7/5 (826 download)
Download or read book Ambient Ionization Mass Spectrometry written by Marek Domin and published by Royal Society of Chemistry. This book was released on 2014-11-14 with total page 529 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ambient ionization has emerged as one of the hottest and fastest growing topics in mass spectrometry enabling sample analysis with minimal sample preparation. Introducing the subject and explaining the basic concepts and terminology, this book will provide a comprehensive, unique treatise devoted to the subject. Written by acknowledged experts, there are full descriptions on how new ionization techniques work, with an overview of their strengths, weaknesses and applications. This title will bring the reader right up to date, with both applications and theory, and will be suitable as a tutorial text for those starting in the field from a variety of disciplines.
Author : Clara Leigh Feider
Publisher :
ISBN 13 :
Total Pages : 390 pages
Book Rating : 4.:/5 (125 download)
Download or read book Advanced Development of Ambient Ionization Mass Spectrometry Imaging Methods and Their Utilization Towards the Understanding of Metabolic Diseases written by Clara Leigh Feider and published by . This book was released on 2020 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ambient ionization mass spectrometry (MS) technologies offer a unique opportunity to bring the specificity and sensitivity of MS into clinics, potentially allowing rapid analyses of biospecimens without need for sample preparation or highly trained personnel. As these technologies offer significant advantages over current technologies in terms of speed and suitability for a hospital environment, ambient ionization methods have been applied to a wide variety of clinical applications such as disease diagnosis, therapeutic drug monitoring, and biomarker discovery. Despite these successes, there remain challenges for these methods to overcome before they can be relied upon for routine analysis of patient samples. Prior to their use by physicians to inform decisions regarding patient care, ambient ionization MS technologies must be robust, versatile, and be shown to improve patient outcomes by providing information that is lacking in current standard of care procedures. This dissertation serves to outline recent advancements made towards the improvements of ambient ionization MS technologies as well as the application of these techniques towards disease indications that have yet to be explored. Chapter 2 provides data and discussion about how relative humidity can contribute to variability and poor data quality during desorption electrospray ionization (DESI) MS experiments, providing essential information about how atmospheric conditions can contribute to the robustness of the technique. Chapters 3 and 4 present methods for integration of new separation and fragmentation techniques with ambient ionization methods in order to increase the amount of information that can be gathered from a biological specimen. Finally, Chapter 5 presents results from the utilization of DESI-MS imaging towards understanding endometriosis, a chronic gynecological condition that has limited diagnosis and treatment options for patients. The entirety of this work aims to discuss how further improvements to ambient ionization MS technologies can make them useful for understanding a wider variety of disease processes and the progress that is being made to this end
Author : Annemie Bogaerts
Publisher : MDPI
ISBN 13 : 3038977500
Total Pages : 248 pages
Book Rating : 4.0/5 (389 download)
Download or read book Plasma Catalysis written by Annemie Bogaerts and published by MDPI. This book was released on 2019-04-02 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plasma catalysis is gaining increasing interest for various gas conversion applications, such as CO2 conversion into value-added chemicals and fuels, N2 fixation for the synthesis of NH3 or NOx, methane conversion into higher hydrocarbons or oxygenates. It is also widely used for air pollution control (e.g., VOC remediation). Plasma catalysis allows thermodynamically difficult reactions to proceed at ambient pressure and temperature, due to activation of the gas molecules by energetic electrons created in the plasma. However, plasma is very reactive but not selective, and thus a catalyst is needed to improve the selectivity. In spite of the growing interest in plasma catalysis, the underlying mechanisms of the (possible) synergy between plasma and catalyst are not yet fully understood. Indeed, plasma catalysis is quite complicated, as the plasma will affect the catalyst and vice versa. Moreover, due to the reactive plasma environment, the most suitable catalysts will probably be different from thermal catalysts. More research is needed to better understand the plasma–catalyst interactions, in order to further improve the applications.
Author : Edmond de Hoffmann
Publisher : Wiley
ISBN 13 : 9780471485650
Total Pages : 420 pages
Book Rating : 4.4/5 (856 download)
Download or read book Mass Spectrometry written by Edmond de Hoffmann and published by Wiley. This book was released on 2001-10-10 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: Offers a complete overview of the principles, theories and key applications of modern mass spectrometry in this introductory textbook. Following on from the highly successful first edition, this edition is extensively updated including new techniques and applications. All instrumental aspects of mass spectrometry are clearly and concisely described; sources, analysers and detectors. * Revised and updated * Numerous examples and illustrations are combined with a series of exercises to help encourage student understanding * Includes biological applications, which have been significantly expanded and updated * Also includes coverage of ESI and MALDI
Author : Kenzo Hiraoka
Publisher : Springer Science & Business Media
ISBN 13 : 1461472334
Total Pages : 241 pages
Book Rating : 4.4/5 (614 download)
Download or read book Fundamentals of Mass Spectrometry written by Kenzo Hiraoka and published by Springer Science & Business Media. This book was released on 2013-06-13 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: Most research and all publications in mass spectrometry address either applications or practical questions of procedure. This book, in contrast, discusses the fundamentals of mass spectrometry. Since these basics (physics, chemistry, kinetics, and thermodynamics) were worked out in the 20th century, they are rarely addressed nowadays and young scientists have no opportunity to learn them. This book reviews a number of useful methods in mass spectrometry and explains not only the details of the methods but the theoretical underpinning.
Author : Wolfgang H. Binder
Publisher : John Wiley & Sons
ISBN 13 : 3527670203
Total Pages : 638 pages
Book Rating : 4.5/5 (276 download)
Download or read book Self-Healing Polymers written by Wolfgang H. Binder and published by John Wiley & Sons. This book was released on 2013-03-29 with total page 638 pages. Available in PDF, EPUB and Kindle. Book excerpt: Self-healing is a well-known phenomenon in nature: a broken bone merges after some time and if skin is damaged, the wound will stop bleeding and heals again. This concept can be mimicked in order to create polymeric materials with the ability to regenerate after they have suffered degradation or wear. Already realized applications are used in aerospace engineering, and current research in this fascinating field shows how different self-healing mechanisms proven successful by nature can be adapted to produce even more versatile materials. The book combines the knowledge of an international panel of experts in the field and provides the reader with chemical and physical concepts for self-healing polymers, including aspects of biomimetic processes of healing in nature. It shows how to design self-healing polymers and explains the dynamics in these systems. Different self-healing concepts such as encapsulated systems and supramolecular systems are detailed. Chapters on analysis and friction detection in self-healing polymers and on applications round off the book.
Author : Nicole A. Keefe
Publisher : Springer Nature
ISBN 13 : 3031525469
Total Pages : 624 pages
Book Rating : 4.0/5 (315 download)
Download or read book IR Playbook written by Nicole A. Keefe and published by Springer Nature. This book was released on 2024 with total page 624 pages. Available in PDF, EPUB and Kindle. Book excerpt: This fully updated new edition is a comprehensive guide to interventional radiology (IR) for medical students, residents, early career attendings, nurse practitioners and physician assistants. The IR Playbook includes procedures, new and updated data, and new images, to stay on the cutting edge of IR. As a specialty, IR is constantly changing and evolving to apply newer technologies and techniques to a breadth of disease pathologies. This book addresses the growing need for a reference for trainees and early career professionals to gain a solid foundation. Let this book serve as your only resource from the first day you find out about IR to the day you take your certifying exam. One and done. The textbook is divided into two main sections, with many images and key point boxes throughout that offer high-yield pearls along with the specific How To's necessary for practice. The first section is designed to give readers an introduction to IR, including radiation safety, commonly used devices, patient care, and anatomy. The second portion is divided by procedure. These chapters cover pathophysiology, indications for treatment, as well as alternative treatments before delving into interventional therapy. This new edition has been fully updated throughout including several brand-new procedures and divided chapters to allow a more in depth look at several disease pathologies. IR Playbook gives medical students, residents, and trainees a full perspective of interventional radiology.
Author : Radislav A. Potyrailo
Publisher : Springer Science & Business Media
ISBN 13 : 0387737138
Total Pages : 495 pages
Book Rating : 4.3/5 (877 download)
Download or read book Combinatorial Methods for Chemical and Biological Sensors written by Radislav A. Potyrailo and published by Springer Science & Business Media. This book was released on 2009-03-21 with total page 495 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chemical sensors are in high demand for applications as varied as water pollution detection, medical diagnostics, and battlefield air analysis. Designing the next generation of sensors requires an interdisciplinary approach. The book provides a critical analysis of new opportunities in sensor materials research that have been opened up with the use of combinatorial and high-throughput technologies, with emphasis on experimental techniques. For a view of component selection with a more computational perspective, readers may refer to the complementary volume of Integrated Analytical Systems edited by M. Ryan et al., entitled “Computational Methods for Sensor Material Selection”.
Author : Antonia Perez De Los Rios
Publisher : Elsevier
ISBN 13 : 044463262X
Total Pages : 379 pages
Book Rating : 4.4/5 (446 download)
Download or read book Ionic Liquids in Separation Technology written by Antonia Perez De Los Rios and published by Elsevier. This book was released on 2014-08-08 with total page 379 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ionic Liquids in Separation Technology reports on the most important fundamental and technological advances in separation processes using ionic liquids. It brings together the latest developments in this fascinating field, supplements them with numerous practical tips, and thus provides those working in both research and industry with an indispensable source of information. The book covers fundamental topics of physical, thermal, and optical properties of ionic liquids, including green aspects. It then moves on to contexts and applications, including separation of proteins, reduction of environmental pollutants, separation of metal ions and organic compounds, use in electrochromic devices, and much more. For the specialist audience the book serves as a recompilation of the most important knowledge in this field, whereas for starting researchers in ionic liquid separation technology the book is a great introduction to the field. First book in the marketplace dedicated to ionic liquids in separation technology Contributions from scientists in academia and researchers in industry ensure the coverage of both scientific fundamentals and industrial applications Covers a broad collection of applications in separation technology which makes the book a single source of information Includes many practical tips for researchers in industry and scientists who apply ionic liquids in their work
Author : Kevin Downard
Publisher : Royal Society of Chemistry
ISBN 13 : 1788018273
Total Pages : 228 pages
Book Rating : 4.7/5 (88 download)
Download or read book Mass Spectrometry written by Kevin Downard and published by Royal Society of Chemistry. This book was released on 2019-05-16 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mass Spectrometry: A Foundation Course is a textbook covering the field of mass spectrometry across the chemical, physical, biological, medical and environmental sciences. Sufficient depth is provided for the reader to appreciate the reasons behind and basis for particular experiments. It is uniquely and logically organised to enable the book to form the basis for a university course in mass spectrometry at the undergraduate or postgraduate level. This is achieved by combining specific core sections coupled to optional areas of study tailored to students of the chemical, physical, biological, medical and environmental sciences. Recommended course structures are provided in the front of the book. Dedicated chapters are included on: organic mass spectrometry; ion chemistry - to emphasise the role of mass spectrometry in fundamental chemistry and physics; biological mass spectrometry including proteomics; mass spectrometry in medicine, environmental and surface science and accelerator mass spectrometry, to emphasise the importance of these areas. Each chapter concludes with key references and additional recommended reading material, making the book an excellent springboard to further study. Highly readable, easy-to-use and logically presented, Mass Spectrometry: A Foundation Course is an ideal text for students and for those who work with mass spectrometers who wish to gain a solid understanding of the basics in modern mass spectrometry.
Author : Julie D. Thompson
Publisher : Humana Press
ISBN 13 : 9781588299710
Total Pages : 0 pages
Book Rating : 4.2/5 (997 download)
Download or read book Functional Proteomics written by Julie D. Thompson and published by Humana Press. This book was released on 2008-08-12 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: As the emerging field of proteomics continues to expand at an extremely rapid rate, the relative quantification of proteins, targeted by their function, becomes its greatest challenge. Complex analytical strategies have been designed that allow comparative analysis of large proteomes, as well as in depth detection of the core proteome or the interaction network of a given protein of interest. In Functional Proteomics: Methods and Protocols, expert researchers describe the latest protocols being developed to address the problems encountered in high-throughput proteomics projects, with emphasis on the factors governing the technical choices for given applications. The case studies within the volume focus on the following three crucial aspects of the experimental design: 1) the strategy used for the selection, purification and preparation of the sample to be analyzed by mass spectrometry, 2) the type of mass spectrometer used and the type of data to be obtained from it, and 3) the method used for the interpretation of the mass spectrometry data and the search engine used for the identification of the proteins in the different types of sequence data banks available. As a part of the highly successful Methods in Molecular BiologyTM series, the chapters compile step-by-step, readily reproducible laboratory protocols, lists of the necessary materials and reagents, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and cutting-edge, Functional Proteomics: Methods and Protocols is an ideal resource for all scientists pursuing this developing field and its multitudinous data.
Author : Yuichiro Himeda
Publisher : John Wiley & Sons
ISBN 13 : 3527346635
Total Pages : 322 pages
Book Rating : 4.5/5 (273 download)
Download or read book CO2 Hydrogenation Catalysis written by Yuichiro Himeda and published by John Wiley & Sons. This book was released on 2021-06-28 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: A guide to the effective catalysts and latest advances in CO2 conversion in chemicals and fuels Carbon dioxide hydrogenation is one of the most promising and economic techniques to utilize CO2 emissions to produce value-added chemicals. With contributions from an international team of experts on the topic, CO2 Hydrogenation Catalysis offers a comprehensive review of the most recent developments in the catalytic hydrogenation of carbon dioxide to formic acid/formate, methanol, methane, and C2+ products. The book explores the electroreduction of carbon dioxide and contains an overview on hydrogen production from formic acid and methanol. With a practical review of the advances and challenges in future CO2 hydrogenation research, the book provides an important guide for researchers in academia and industry working in the field of catalysis, organometallic chemistry, green and sustainable chemistry, as well as energy conversion and storage. This important book: Offers a unique review of effective catalysts and the latest advances in CO2 conversion Explores how to utilize CO2 emissions to produce value-added chemicals and fuels such as methanol, olefins, gasoline, aromatics Includes the latest research in homogeneous and heterogeneous catalysis as well as electrocatalysis Highlights advances and challenges for future investigation Written for chemists, catalytic chemists, electrochemists, chemists in industry, and chemical engineers, CO2 Hydrogenation Catalysis offers a comprehensive resource to understanding how CO2 emissions can create value-added chemicals.
Author : Lisa M. Balbes
Publisher :
ISBN 13 : 9780195183665
Total Pages : 326 pages
Book Rating : 4.1/5 (836 download)
Download or read book Nontraditional Careers for Chemists written by Lisa M. Balbes and published by . This book was released on 2007 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Chemistry background prepares you for much more than just a laboratory career. The broad science education, analytical thinking, research methods, and other skills learned are of value to a wide variety of types of employers, and essential for a plethora of types of positions. Those who are interested in chemistry tend to have some similar personality traits and characteristics. By understanding your own personal values and interests, you can make informed decisions about what career paths to explore, and identify positions that match your needs. By expanding your options for not only what you will do, but also the environment in which you will do it, you can vastly increase the available employment opportunities, and increase the likelihood of finding enjoyable and lucrative employment. Each chapter in this book provides background information on a nontraditional field, including typical tasks, education or training requirements, and personal characteristics that make for a successful career in that field. Each chapter also contains detailed profiles of several chemists working in that field. The reader gets a true sense of what these people do on a daily basis, what in their background prepared them to move into this field, and what skills, personality, and knowledge are required to make a success of a career in this new field. Advice for people interested in moving into the field, and predictions for the future of that career, are also included from each person profiled. Career fields profiled include communication, chemical information, patents, sales and marketing, business development, regulatory affairs, public policy, safety, human resources, computers, and several others. Taken together, the career descriptions and real case histories provide a complete picture of each nontraditional career path, as well as valuable advice about how career transitions can be planned and successfully achieved by any chemist.
Author : Ian Colbeck
Publisher : John Wiley & Sons
ISBN 13 : 1119977924
Total Pages : 522 pages
Book Rating : 4.1/5 (199 download)
Download or read book Aerosol Science written by Ian Colbeck and published by John Wiley & Sons. This book was released on 2014-02-03 with total page 522 pages. Available in PDF, EPUB and Kindle. Book excerpt: AEROSOL SCIENCE TECHNOLOGY AND APPLICATIONS Aerosols influence many areas of our daily life. They are at the core of environmental problems such as global warming, photochemical smog and poor air quality. They can also have diverse effects on human health, where exposure occurs in both outdoor and indoor environments. However, aerosols can have beneficial effects too; the delivery of drugs to the lungs, the delivery of fuels for combustion and the production of nanomaterials all rely on aerosols. Advances in particle measurement technologies have made it possible to take advantage of rapid changes in both particle size and concentration. Likewise, aerosols can now be produced in a controlled fashion. Reviewing many technological applications together with the current scientific status of aerosol modelling and measurements, this book includes: Satellite aerosol remote sensing The effects of aerosols on climate change Air pollution and health Pharmaceutical aerosols and pulmonary drug delivery Bioaerosols and hospital infections Particle emissions from vehicles The safety of emerging nanomaterials Radioactive aerosols: tracers of atmospheric processes With the importance of this topic brought to the public's attention after the eruption of the Icelandic volcano Eyjafjallajökull, this book provides a timely, concise and accessible overview of the many facets of aerosol science.
