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Author : John Coltart
Publisher :
ISBN 13 :
Total Pages : 380 pages
Book Rating : 4.3/5 (555 download)
Download or read book Recent Developments in Cardiovascular Drugs written by John Coltart and published by . This book was released on 1982 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : John Somberg
Publisher : CRC Press
ISBN 13 : 0824746317
Total Pages : 259 pages
Book Rating : 4.8/5 (247 download)
Download or read book Cardiovascular Drug Development written by John Somberg and published by CRC Press. This book was released on 1998-11-04 with total page 259 pages. Available in PDF, EPUB and Kindle. Book excerpt: These multidisciplinary presentations provide information essential to devising effective drug protocols in cardiovascular drug development, facilitating the approval process. Guides researchers and developers through the government drug approval process, facilitating development, minimizing costs, and harmonizing international standards employed in the creation of vital new cardiovascular therapies! Cardiovascular Drug Development explores the delicate balance of efficacy and safety that cardiovascular therapy must achieve to gain regulatory approval discusses the search for surrogates and the need in some areas for natural history endpoints reviews optimum strategies for protocol design in the development of drugs to treat hypertension, cardiac arrhythmias, heart failure, coronary artery disease, and hypercholesterolemia and other lipid disorders compares and contrasts the varying standards of evidence for drug approval in the United States, Europe, and Asia and more! Cardiovascular Drug Development will prove to be a valuable asset for cardiologists, pharmacologists and pharmacists, regulatory affairs specialists, and directors of research and development for pharmaceutical companies.
Author : Matthew J Killeen
Publisher : World Scientific
ISBN 13 : 9814464406
Total Pages : 189 pages
Book Rating : 4.8/5 (144 download)
Download or read book Cardiac Drug Safety: A Bench To Bedside Approach written by Matthew J Killeen and published by World Scientific. This book was released on 2012-02-02 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ensuring the safety of new medical products remains a major challenge for the pharmaceutical industry. Cardiac safety, particularly drug-induced heart rhythm abnormalities, remains an important cause of pipeline attrition and has resulted in countless major product recalls or label changes. The risk of encountering this major adverse event continues to shape the drug development and regulatory landscape.Extensive research over the past decade has shed light on the root causes of arrhythmias that are triggered by medications and has helped drive, and optimize, drug safety testing. However, current cardiac safety platforms have several limitations and there remains a pressing unmet need to improve the predictive power of today's drug safety tests.Fundamental to addressing the problem of drug-induced arrhythmias, and to reducing the impact of this safety signal on drug development, is a complete understanding of how these events may arise, what cardiac safety tests are currently used, and what opportunities there are to enhance patient safety and reduce the risk of detecting cardiac toxicity in later stages of product commercialization. By introducing the reader to these core concepts, this book delivers key insight into the increasingly important and dynamic field of cardiac safety.
Author : Atta-ur-Rahman
Publisher : Bentham Science Publishers
ISBN 13 : 1681081636
Total Pages : 406 pages
Book Rating : 4.6/5 (81 download)
Download or read book Frontiers in Cardiovascular Drug Discovery written by Atta-ur-Rahman and published by Bentham Science Publishers. This book was released on 2016-11-01 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: Frontiers in Cardiovascular Drug Discovery is an eBook series devoted to publishing the latest advances in cardiovascular drug design and discovery. Each volume brings reviews on the biochemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships of molecules used in cardiovascular therapy. The eBook series should prove to be of great interest to all medicinal chemists and pharmaceutical scientists involved in preclinical and clinical research in cardiology. The third volume of the series covers the following topics: - P2Y12 receptor agonists -Heart failure pharmacotherapy -Vasopressin and the cardiovascular system -Cerebral small vessel disease -Complement blocking therapeutic strategies -New antiplatelet and anticoagulating agents for gastrointestinal treatments
Author : Deepak L. Bhatt
Publisher : Elsevier Health Sciences
ISBN 13 : 0323673627
Total Pages : 723 pages
Book Rating : 4.3/5 (236 download)
Download or read book Opie's Cardiovascular Drugs: A Companion to Braunwald's Heart Disease E-Book written by Deepak L. Bhatt and published by Elsevier Health Sciences. This book was released on 2020-10-20 with total page 723 pages. Available in PDF, EPUB and Kindle. Book excerpt: Authoritative, portable, and up to date, Opie’s Cardiovascular Drugs, 9th Edition, is the definitive reference for quick access to frequently used drugs in all phases of care for cardiac patients. Now a part of the Braunwald family of renowned cardiology references, this compact title provides crucial information in an easily accessible format—ideal for cardiologists, residents, cardiology fellows, medical students, nurses, and other cardiac care providers. Updated to include the latest guidelines and evidence-based implications, it offers clear and concise explanations and pertinent clinical facts for all classes of cardiac drugs, as well as all the latest clinical trial results and evidence for the pharmacologic treatment of heart disease. Uses a new, consistent format for each drug class: overview and guidelines for use, mechanisms of action, differences among drugs in class, data for use, side effects, and drug interactions. Covers key topics such as new ESC and NLA guidelines, advances in lipid-lowering therapy, new diabetes drugs that improve cardiovascular outcomes, obesity drugs and cardiovascular and metabolic effects, drugs targeting inflammation, and combinations of antithrombotic therapies with analysis of risk-benefit. Provides guidance on how to effectively manage comorbid diseases. Contains dozens of unique “Opiegram diagrams that demystify complex mechanisms of action and other drug processes—many updated to reflect current pathologic understanding of mechanisms.
Author : William H. Frishman, MD
Publisher : Cardiotext Publishing
ISBN 13 : 1935395629
Total Pages : 798 pages
Book Rating : 4.9/5 (353 download)
Download or read book Cardiovascular Pharmacotherapeutics written by William H. Frishman, MD and published by Cardiotext Publishing. This book was released on 2011-05-11 with total page 798 pages. Available in PDF, EPUB and Kindle. Book excerpt: Everything practicing physicians and pharmacists need to know about drug therapy for cardiovascular disease. A critically acclaimed classic reference now in its third edition, Cardiovascular Pharmacotherapeutics provides current information regarding the contemporary use of all available cardiovascular medications for adults and children. Strongly emphasizing the scientific rationale behind the use of such therapies in cardiac disease, it discusses new drugs and novel compounds that are under development and may emerge as the cardiac therapies of the future. This edition also addresses special considerations for drug therapy use in the elderly, during pregnancy, and in those with hepatic or renal disease. A generous assortment of tables, figures, and appendices guides readers in their investigations of each drug group and various disease states. This new third edition presents an in-depth discussion of: All cardiovascular agents currently available The scientific basis behind every pharmacotherapy advance Mechanisms of action of cardiovascular pharmacotherapeutics The latest advances in cardiovascular drug therapy Specific drug treatments, and information on recently approved drugs Molecular biological advances Drugs in development Hands-on discussions of how to utilize specific drugs for treatment of various cardiovascular disorders and for the prevention of disease Also included are 8 appendices that provide practical, hands-on information on using drugs in clinical settings, including relevant pharmacokinetic information, and practical drug prescribing information. All updated with an accompanying website, Advances in Cardiovascular Pharmacotherapeutics www.cvpct3.com
Author : Y. Robert Li
Publisher : John Wiley & Sons
ISBN 13 : 0470915374
Total Pages : 501 pages
Book Rating : 4.4/5 (79 download)
Download or read book Cardiovascular Diseases written by Y. Robert Li and published by John Wiley & Sons. This book was released on 2015-04-06 with total page 501 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written in an accessible style and consistent format, the book covers both the fundamentals and advances in the pharmacology of cardiovascular drugs, as well as their integrated applications in the management of individual cardiovascular diseases. • Integrates fundamentals and recent advances regarding cardiovascular drugs, blending basic and clinical sciences needed to effectively understand and treat cardiovascular diseases • Facilitates understanding of drug action and mechanism by covering physiology / pathophysiology and pharmacology • Includes guidelines and algorithms for pharmacotherapeutic management of cardiovascular diseases • Uses case presentations and study questions to enhance understanding of the material • Serves as a resource for pharmaceutical and medical students and researchers interested in cardiovascular issues
Author : John Hamer
Publisher :
ISBN 13 :
Total Pages : 528 pages
Book Rating : 4.:/5 (43 download)
Download or read book Recent Advances in Cardiology written by John Hamer and published by . This book was released on 1977 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Atta-ur-Rahman
Publisher : Bentham Science Publishers
ISBN 13 : 9811413231
Total Pages : 278 pages
Book Rating : 4.8/5 (114 download)
Download or read book Frontiers in Cardiovascular Drug Discovery: Volume 5 written by Atta-ur-Rahman and published by Bentham Science Publishers. This book was released on 2020-10-02 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: Frontiers in Cardiovascular Drug Discovery is a book series devoted to publishing the latest advances in cardiovascular drug design and discovery. Each volume brings reviews on the biochemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships of molecules used in cardiovascular therapy. The book series should prove to be of great interest to all medicinal chemists and pharmaceutical scientists involved in preclinical and clinical research in cardiology. The fifth volume of the series covers the following topics: -The Lipid Hypothesis: From Resins to Proprotein Convertase Subtilisin/Kexin Type-9 Inhibitors -The Role of SGLT2i in the Prevention and Treatment of Heart Failure -Natural Products and Semi-Synthetic Compounds as Antithrombotics: A Review of the Last Ten Years (2009-2019) -Transient Receptor Potential Channels: Therapeutic Targets for Cardiometabolic Diseases? -Treatment of Raynaud’s Phenomenon -Traditional Medicine Based Cardiovascular Therapeutics -Cardiovascular Disease: A Systems Biology Approach
Author : Michael K. Pugsley
Publisher : Humana Press
ISBN 13 : 9781588290977
Total Pages : 431 pages
Book Rating : 4.2/5 (99 download)
Download or read book Cardiac Drug Development Guide written by Michael K. Pugsley and published by Humana Press. This book was released on 2003-07-30 with total page 431 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cardiac Drug Development Guide outlines, in detail, the therapeutics of cardiac medicine currently at the cutting edge of scientific research and development around the world. This volume integrates basic and clinical cardiac pharmacology by c- bining, for the first time, both classical and molecular aspects of therapeutic drug development. The chapters comprise a broad spectrum of therapeutic areas and hence involve a comprehensive discussion of molecular, biochemical, and electrophy- ological concepts based on years of in vitro as well as in vivo pharmacological st- ies. In addition, the latter part of the book includes comprehensive clinical cardiac chapters that describe important topics in molecular medicine. These chapters also discuss current clinical therapeutic trends in medicine and provide an evaluation of the efficacy of novel drugs in these areas. Cardiac Drug Development Guide has many distinctive and outstanding features that set it apart from other cardiac pharmacology books. This book introduces topics in an easily understandable format for researchers in many varying disciplines by integrating and thereby simplifying concepts not usually discussed across a broad range of cardiac disciplines and in a highly technical field. Each chapter not only introduces and describes the physiology, pharmacology, and pathophysiology of the disease, but also overviews the clinical implications of drug development, what stages these areas are currently in, and also reviews some of the methodologies involved in drug discovery and development. As a result, this book provides a comprehensive overview of the most advanced procedures in cardiac pharmacology today.
Author : J. Rick Turner
Publisher : Springer
ISBN 13 : 3319403478
Total Pages : 350 pages
Book Rating : 4.3/5 (194 download)
Download or read book Cardiovascular Safety in Drug Development and Therapeutic Use written by J. Rick Turner and published by Springer. This book was released on 2016-07-28 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: At a time when the field of cardiac safety is going through important changes, this unique book provides the rationale for, and cutting-edge explanations of, new regulatory landscapes that will likely govern cardiac safety assessments globally for the foreseeable future. Exposure-response modeling is already being accepted by regulatory agencies in lieu of the traditional Thorough QT/QTc Study, and the Comprehensive in vitro Proarrhythmia Assay initiative is well under way. Developments in the field of cardiovascular safety are also described and discussed in the book. These include the search for more efficient ways to exonerate new drugs for type 2 diabetes from an unacceptable cardiovascular liability, how best to address off-target blood pressure increases induced by noncardiovascular drugs, and the continued evolution of the discipline of Cardio-oncology. “a resource that will likely serve as a standard for years to come” - Dr Jonathan Seltzer Therapeutic Innovation & Regulatory Science, 2017;51(2):180 “I have no hesitation in recommending this book as a valuable reference source” - Dr Rashmi Shah Journal for Clinical Studies, 2017;9(1):62-63
Author : Nagoya University
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (777 download)
Download or read book Cardiovascular Drugs written by Nagoya University and published by . This book was released on 1989 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Derek Rowlands
Publisher : JP Medical Ltd
ISBN 13 : 190781681X
Total Pages : 192 pages
Book Rating : 4.9/5 (78 download)
Download or read book Recent Advances in Cardiology: 16 written by Derek Rowlands and published by JP Medical Ltd. This book was released on 2014-02-10 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: Part of the Recent Advnaces series, Cardiology is a collection of comprehensive reviews, with emphasis on breakthroughs and their practical relevance to clinical practice, providing essential reading to help clinicians and trainees remain up to date in the field.
Author : Arun Kumar
Publisher : BoD – Books on Demand
ISBN 13 : 9535133276
Total Pages : 130 pages
Book Rating : 4.5/5 (351 download)
Download or read book Recent Trends in Cardiovascular Risks written by Arun Kumar and published by BoD – Books on Demand. This book was released on 2017-07-12 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt: Salient features of the book: - All chapters are related to the advances in cardiovascular risks.; - Chapters are written by renowned authors globally. - Chapters are lucid and easy to understand. - Chapters are useful for clinicians, medical practitioners, researchers, teachers, and students. - Chapters include flow charts, diagrams, and tables for easy comprehension of overall risks of cardiovascular disease. - Chapters generate awareness among common people about the risks so that the cost of intensive care units can be prevented, thus the economy of the country.
Author : Adam Schneeweiss
Publisher : Springer
ISBN 13 :
Total Pages : 408 pages
Book Rating : 4.3/5 (91 download)
Download or read book Cardiovascular Drug Therapy in the Elderly written by Adam Schneeweiss and published by Springer. This book was released on 1988-03-31 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cardiovascular drug therapy has markedly progressed in the recent decades. Not only have new drugs been introduced to clinical practice, but new classes of drugs have been developed. While in 1960 the practicing cardiolo gist had a selection of about only ten drugs, in 1987 about 150 drugs are routinely used in cardiovascular diseases. Elderly patients, however, usually do not enjoy the full benefit of this progress. This might be due to lack of knowledge, a conservative approach, or the worldwide tendency not to try new drugs in the elderly. It is now clear that the majority of patients that will be treated in car diovascular clinics will be, in the near future, elderly patients. Even now, elderly patients form about one-third of the patients with cardiovascular diseases. These patients are approached, however, according to criteria devel oped for younger populations. This is despite the fact that elderly patients differ from younger ones in most aspects, including pathology, epidemiol ogy, pathophysiology, diagnostic approach, management, pharmacology, pharmacokinetics, rehabilitation, and supportive treatment. It is the purpose of this book to present to the clinician all drugs with which there is clinical experience in the elderly or which might be potentially useful for the elderly with cardiovascular diseases. The data are presented without the authors taking a position. This should allow the clinicians to make their own selection and individualize treatment, vii viii Preface based on a wide data base. Comparative data are presented only when specific comparative studies were performed.
Author : HK Chopra
Publisher : Jaypee Brothers Medical Publishers
ISBN 13 : 9389587891
Total Pages : 995 pages
Book Rating : 4.3/5 (895 download)
Download or read book Advances & Innovations in Heart Failure (AIHF) written by HK Chopra and published by Jaypee Brothers Medical Publishers. This book was released on 2020-02-28 with total page 995 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heart failure is a serious condition caused by the heart failing to pump enough blood around the body at the right pressure. It usually occurs because the heart muscle has become too weak or stiff to work properly, most commonly caused by heart attack, high blood pressure or cardiomyopathy (heart disease). This textbook is a comprehensive guide to the latest advances in the diagnosis and management of heart failure. Comprising nearly 1000 pages, the book features 15 sections, beginning with discussion on clinical issues of heart failure, followed by imaging techniques. Each of the following sections covers a different disorder or disease that subsequently may lead to heart failure. Topics include coronary artery disease, stroke, arrhythmia, hypertension, nutritional aspects, cardio-oncology, and much more. The book concludes with rehabilitation, legal aspects, and future directions. Authored by internationally recognised experts in the field, the text is further enhanced by clinical photographs, diagrams and tables. Key points Comprehensive guide to latest advances in diagnosis and management of heart failure Extensive text comprising nearly 1000 pages covering numerous associated disorders and diseases Internationally recognised editor and author team Highly illustrated with clinical photographs, diagrams and tables
Author : A.R. Lorimer
Publisher : Springer Science & Business Media
ISBN 13 : 1447131207
Total Pages : 253 pages
Book Rating : 4.4/5 (471 download)
Download or read book Cardiovascular Disease written by A.R. Lorimer and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 253 pages. Available in PDF, EPUB and Kindle. Book excerpt: 'Cardiovascular Disease' is the fourth monograph in the series on management and treatment in major clinical sub specialties or patient groups. Each book is complete in its own right and has been prepared by practising physicians with specialist experience and a particular interest in treatment and management. The series has been prepared to fill a gap between standard textbooks of medicine and therapeutics and research reviews, symposia and original articles in specialist fields. The volumes aim to give authoritative, up-to-date advice on treatment and management which will be of use to both specialists and non-specialists and allow recent advances and developments to be seen in the context of contemporary clinical practice. The first three volumes dealt respectively with gastroin testinal diseases, rheumatic diseases and treatment in the elderly. Cardiovascular disease covers the range of common diseases affect ing the heart and the circulation. In view of the importance of coronary heart disease as a cause of death and morbidity a substan tial part of the book is devoted to description of the factors asso ciated with coronary artery disease (hyperlipidaemia and hypertension) and their management by drug and non-drug means. A further five chapters are devoted to the clinical syndromes asso ciated with coronary heart disease and their management. These not only consider acute 'in hospital' management, including sur gery, but also address epidemiological questions, including approaches to secondary prevention of myocardial infarction.
