Recent Advances In Treatment Of Migraine

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Magnesium in the Central Nervous System

Author : Robert Vink
Publisher : University of Adelaide Press
ISBN 13 : 0987073052
Total Pages : 354 pages
Book Rating : 4.9/5 (87 download)

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Book Synopsis Magnesium in the Central Nervous System by : Robert Vink

Download or read book Magnesium in the Central Nervous System written by Robert Vink and published by University of Adelaide Press. This book was released on 2011 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.

Neurobiological Basis of Migraine

Author : Turgay Dalkara
Publisher : John Wiley & Sons
ISBN 13 : 1118967194
Total Pages : 421 pages
Book Rating : 4.1/5 (189 download)

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Book Synopsis Neurobiological Basis of Migraine by : Turgay Dalkara

Download or read book Neurobiological Basis of Migraine written by Turgay Dalkara and published by John Wiley & Sons. This book was released on 2017-08-07 with total page 421 pages. Available in PDF, EPUB and Kindle. Book excerpt: Published with the New York Academy of Sciences A timely, broad-ranging exploration of the neurobiological basis and molecular mechanisms of migraines Migraines impact the lives of a significant portion of the world's population, afflicting sufferers with severe pain, nausea, and often visual impairment. The WHO views migraines as an important public health issue, and ranks them in its top twenty most disabling illnesses. Neurobiological Basis of Migraine reviews the latest advances made in our understanding of the primary basic mechanisms of migraine headache and provides valuable insights into how these findings are being translated into novel treatment and prevention strategies around the world. Written for researchers and clinicians alike, the book features edited contributions from distinguished experts in the field, taking a focused, yet wide-ranging approach to the subject. It begins by exploring the pathways and networks mediating migraine headaches, their underlying physiological mechanisms, characteristics of visceral pain, and the concept of dural neurogenic inflammation. From there the authors delve into the mechanisms sustaining the head pain and photophobia associated with migraines, and they review the pharmacology of newly discovered migraine treatments. These basic chapters are followed by clinical and genetic studies linking to key issues, including cortical spreading depression, ion channels, transporters, and epilepsy. Reviews of the latest advances in our understanding of the neurobiological basis of migraine Translates important research findings from around the globe into novel treatments strategies currently being investigated Provides researchers and clinicians with a deep understanding of the primary mechanisms of migraine from migraine modeling to clinical applications Includes contributions by many of the most respected researchers in the field, world-wide Discusses exciting recent developments in migraine mutations and their role in CSD, as well as the role of CSD in aura and trigeminal activation Timely, comprehensive, and authoritative, Neurobiological Basis of Migraine is an indispensable working resource for clinicians and migraine, headache, and pain researchers, including neurobiologists, neuropharmacologists, neurologists, and vascular neurobiologists, as well as graduate students in those fields who are involved in researching migraine headaches.

Pituitary Adenylate Cyclase-Activating Polypeptide

Author : Hubert Vaudry
Publisher : Springer Science & Business Media
ISBN 13 : 9781402073069
Total Pages : 432 pages
Book Rating : 4.0/5 (73 download)

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Book Synopsis Pituitary Adenylate Cyclase-Activating Polypeptide by : Hubert Vaudry

Download or read book Pituitary Adenylate Cyclase-Activating Polypeptide written by Hubert Vaudry and published by Springer Science & Business Media. This book was released on 2003 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pituitary Adenylate Cyclase-Activating Polypeptide is the first volume to be written on the neuropeptide PACAP. It covers all domains of PACAP from molecular and cellular aspects to physiological activities and promises for new therapeutic strategies. Pituitary Adenylate Cyclase-Activating Polypeptide is the twentieth volume published in the Endocrine Updates book series under the Series Editorship of Shlomo Melmed, MD.

Headache and Migraine Biology and Management

Author : Seymour Diamond
Publisher : Academic Press
ISBN 13 : 0128011629
Total Pages : 334 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Headache and Migraine Biology and Management by : Seymour Diamond

Download or read book Headache and Migraine Biology and Management written by Seymour Diamond and published by Academic Press. This book was released on 2015-03-13 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: There are two crucial issues in the treatment and management of headache patients: More than 50% of individuals experiencing headache have only been treated symptomatically, with no appropriate diagnosis established; and history and neurologic examination are essential to establishing a diagnosis, and thus selecting appropriate therapy. Headache and Migraine Biology and Management is a practical text that addresses these issues, featuring contributions from expert clinical authors. The book covers in detail topics including chronic and episodic migraine, post-traumatic headache, sinus headache, cluster headache, tension headache, and others. Chapters are also dedicated to treatment subjects, including psychiatric and psychological approaches, medication overuse, inpatient treatment, and pediatric issues. This book is an ideal resource for researchers and clinicians, uniting practical discussion of headache biology, current ideas on etiology, future research, and genetic significance and breakthroughs. This resource is useful to those who want to understand headache biology, treat and manage symptoms, and for those performing research in the headache field. - A practical discussion of headache biology, current ideas on etiology, future research, and genetic significance and breakthroughs - Features chapters from leading physicians and researchers in headache medicine - Full-color text that includes both an overview of multiple disciplines and discusses the measures that can be used to treat headaches

Migraine in Women

Author : Elizabeth Loder
Publisher : PMPH-USA
ISBN 13 : 9781550091809
Total Pages : 212 pages
Book Rating : 4.0/5 (918 download)

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Book Synopsis Migraine in Women by : Elizabeth Loder

Download or read book Migraine in Women written by Elizabeth Loder and published by PMPH-USA. This book was released on 2004 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fifteen specialists serve as chapter authors, covering sex hormones and genetics, as well as the social, cultural, psychiatric, and psychological factors that contribute to headache disorders. Their approach is evidence-based, but where there are gaps in research, the authors provide advice based on expert consensus and clinical experience. Each chapter opens with a case report that synthesizes the chapter's treatment recommendations, as well as key points listing the chapter's contents. The main body of the chapter features an introductory overview, a closing summary, tables, and an extensive list of suggestive reading.

White Matter Diseases

Author : Massimo Filippi
Publisher : Springer Nature
ISBN 13 : 303038621X
Total Pages : 215 pages
Book Rating : 4.0/5 (33 download)

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Book Synopsis White Matter Diseases by : Massimo Filippi

Download or read book White Matter Diseases written by Massimo Filippi and published by Springer Nature. This book was released on 2020-02-13 with total page 215 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides cutting-edge information on the epidemiology, etiopathogenesis, clinical manifestations, diagnostic procedures and treatment approaches for the main white matter (WM) disorders of the central nervous system (CNS). WM lesions are associated with many neurological conditions, and with aging. The diagnostic work-up of neurological diseases characterized by the presence of these lesions has changed dramatically over the past few years. This is mainly due on the one hand to the discovery of specific pathogenetic factors in some of these conditions, and on the order to the optimized use of diagnostic tools. All of this has resulted in new diagnostic algorithms, and in the identification of new neurological conditions. The book offers neurologists essential guidance in the diagnosis and treatment of the most frequent WM conditions, promoting their correct and cost-saving diagnosis and management. By integrating neurological, laboratory and imaging concepts with the demands of accurate diagnosis, this reference guide provides a state-of-the-art overview of the current state of knowledge on these conditions, as well as practical guidelines for their diagnosis and treatment.

Chronic Daily Headache for Clinicians

Author : Peter J. Goadsby
Publisher : PMPH-USA
ISBN 13 : 9781550092653
Total Pages : 248 pages
Book Rating : 4.0/5 (926 download)

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Book Synopsis Chronic Daily Headache for Clinicians by : Peter J. Goadsby

Download or read book Chronic Daily Headache for Clinicians written by Peter J. Goadsby and published by PMPH-USA. This book was released on 2005 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: The frequent headache syndromes are among the most challenging disorders that confront clinicians on a routine basis. The purpose of Chronic Daily Headache for Clinicians is to provide a practical guide for clinicians to both understand and manage patients with frequent headache. The foremost clinicians in each area will review in a very focused way the diagnostic and management issues for the most important and challenging disorders that present with frequent headache. Specific types of headaches examined include Chronic Migraine, Tension-Type, Chronic Cluster, Hypnic, Low-CSF Volume, and those headaches associated with Head Trauma, among others. Chronic Daily Headache for Clinicians will bring clinical clarity to these disorders in order to be appropriately studied in terms of their primary headache biology.

Migraine

Author : Katherine Foxhall
Publisher : Johns Hopkins University Press
ISBN 13 : 1421429489
Total Pages : 293 pages
Book Rating : 4.4/5 (214 download)

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Book Synopsis Migraine by : Katherine Foxhall

Download or read book Migraine written by Katherine Foxhall and published by Johns Hopkins University Press. This book was released on 2019-06-18 with total page 293 pages. Available in PDF, EPUB and Kindle. Book excerpt: Deeply researched and beautifully written, this fascinating and accessible study of one of our most common, disabling—and yet often dismissed—disorders will appeal to physicians, historians, scholars in medical humanities, and people living with migraine alike.

Mechanism and Management of Headache

Author : James Waldo Lance
Publisher : Butterworth-Heinemann
ISBN 13 :
Total Pages : 344 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Mechanism and Management of Headache by : James Waldo Lance

Download or read book Mechanism and Management of Headache written by James Waldo Lance and published by Butterworth-Heinemann. This book was released on 1998 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive reference for any medical practitioner dealing with headache patients. Explains such aspects as taking a medical history, diagnosis and physical examination, details of each type of headache organized according to the International Headache Society classification, pathophysiology, and new medications. Draws from empirical studies, clinical experience, insights acquired from functional magnetic-resonance imaging and positron-emission tomography scanning, and new research on the neurotransmitters involved in producing headaches. First published in 1969, and most recently in 1993; Goadsby (neurology, U. College London) joins Lance (neurology, U. of New South Wales) for this edition. Annotation copyrighted by Book News, Inc., Portland, OR

Pharmacological Management of Headaches

Author : Dimos D. Mitsikostas
Publisher : Springer
ISBN 13 : 3319199110
Total Pages : 253 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Pharmacological Management of Headaches by : Dimos D. Mitsikostas

Download or read book Pharmacological Management of Headaches written by Dimos D. Mitsikostas and published by Springer. This book was released on 2015-08-26 with total page 253 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book, headache experts summarize all the currently available therapies for primary headaches and most importantly, describe the ‘tricks’ that can ensure the success of headache pharmacotherapy. Prevention and acute treatment of migraine and cluster headache receive particular attention and individual chapters are devoted to the treatment of primary headaches in special groups, i.e. children, pregnant women and the elderly. Further chapters focus on selected secondary headache disorders and cranial neuralgias for which pharmacotherapy is available. The book is designed to meet the daily practice needs of general physicians, general neurologists, neurologists in training and medical students. Headache remains a leading reason for people to seek medical consultation, and migraine and other primary headache disorders are classified by the WHO as among the most disabling medical conditions in the general population, often affecting individuals during their most productive years. Unfortunately, under treatment and mismanagement are the fate of many headache patients and this book provides a sound basis for optimizing treatment.

Pathophysiology of Headaches

Author : Messoud Ashina
Publisher : Springer
ISBN 13 : 3319156217
Total Pages : 277 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Pathophysiology of Headaches by : Messoud Ashina

Download or read book Pathophysiology of Headaches written by Messoud Ashina and published by Springer. This book was released on 2015-04-14 with total page 277 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a detailed overview of the current state of knowledge regarding the pathophysiology of both primary headaches – migraine, tension-type headache (TTH), and cluster headache – and the very important and frequent type of secondary headache, medication overuse headache (MOH). After an introductory chapter describing relevant neuroanatomy and vascular anatomy, the evidence gained from animal models regarding the pathophysiology of migraine and the other primary headaches is reviewed. Knowledge of the genetic component in the different types of headache is then examined with reference to recent evidence, for example regarding the implication of the trigeminovascular system and cortical spreading depression in migraine. Detailed information is provided on insights into primary headaches from imaging studies, including functional magnetic resonance imaging and positron emission tomography and on their neurophysiology and biochemistry. A further series of important chapters describe present knowledge of the pathophysiology of each specific type of headache and consider future directions. Written by acknowledged experts in their fields from Europe and the United States, clinicians and students will find Pathophysiology of Headaches to be an excellent source of up-to-date information on why patients experience headaches. In addition, it will be of value for pain researchers investigating the underlying mechanisms of headache.

Drug-Induced Headache

Author : Hans-Christoph Diener
Publisher : Springer Science & Business Media
ISBN 13 : 3642733271
Total Pages : 174 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis Drug-Induced Headache by : Hans-Christoph Diener

Download or read book Drug-Induced Headache written by Hans-Christoph Diener and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt: M. WILKINSON Patients with frequent or daily headaches pose a very difficult problem for the physician who has to treat them, particularly as many patients think that there should be a medicine or medicines which give them instant relief. In the search for the compound which would meet this very natural desire, many drugs have been manufactured and the temptation for the physician is either to increase the dose of a drug which seems to be, at any rate, partially effective, or to add one or more drugs to those which the patient is already taking. Although there have been some references to the dangers of overdosage of drugs for migraine in the past, it was not until relatively recently that it was recognized that drugs given for the relief of headache, if taken injudiciously, may themselves cause headache. The first drugs to be implicated in this way were ergotamine and phenazone. In the case of ergotamine tartrate, the dangers of ergotism were well known as this was a disorder which had been known and written about for many years. In the treatment of headache, fully blown ergotism is rare and in recent years has usually been due to self-medication in doses much greater than those prescribed although there are a few recorded cases where toxic amounts have been given.

Migraine

Author : Robert A. Davidoff
Publisher : Oxford University Press
ISBN 13 : 0198031351
Total Pages : 533 pages
Book Rating : 4.1/5 (98 download)

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Book Synopsis Migraine by : Robert A. Davidoff

Download or read book Migraine written by Robert A. Davidoff and published by Oxford University Press. This book was released on 2002-02-14 with total page 533 pages. Available in PDF, EPUB and Kindle. Book excerpt: Migraine: Manifestations, Pathophysiology, and Management, Second Edition, is a much expanded, updated monograph that focuses in detail on migraine's diverse variations, its pathophysiology, and its treatment. Authored by a clinician/scientist who himself suffers from migraine, the book's premise is that the clinical significance of migraine and its treatment are intelligible only if the physician understands the anatomical, physiological, and pharmacological factors underlying both head pain and the other manifestations of migraine. The book provides clear clinical descriptions of the myriad of specific migraine syndromes, and discusses the rationale for, and elements of, a sensitive, inclusive patient history. Also covered are important but sometimes ignored topics such as environmental triggering of migraine and myofascial syndromes. The Second Edition also bridges the gap between basic science and clinical practice by explaining those substantive advances made in understanding fundamental mechanisms of head pain and aura. Recent knowledge about genetics, hormonal changes, cerebral circulation, nitric oxide, peptides, central sensitization of trigeminal neurons, and the role of periaqueductal gray matter buttress the discussion of basic mechanisms. On the treatment side, the Second Edition reflects the impressive advances in pharmacological approaches to migraine. There is a greatly expanded section on the triptans and their mechanisms of action, and rationales and practical information about the use of all other viable anti-migraine and prophylactic drugs. Psychobiological aspects of stress and stress management, elimination of environmental stimuli, the educational facets of management, and aspects of the patient/physician interaction so crucial in the treatment of migraine are all discussed. Special problems associated with the care of women, children, the elderly, patients with intractable headaches, and emergency department patients are thoroughly reviewed. In sum, this scholarly, well-referenced book offers in one volume a comprehensive scientific and clinical discussion of migraine headache.

ABC of Headache

Author : Anne MacGregor
Publisher : John Wiley & Sons
ISBN 13 : 1118682009
Total Pages : 88 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis ABC of Headache by : Anne MacGregor

Download or read book ABC of Headache written by Anne MacGregor and published by John Wiley & Sons. This book was released on 2013-05-20 with total page 88 pages. Available in PDF, EPUB and Kindle. Book excerpt: In its different presentations, headache is one of the most commonsymptoms seen by family practitioners. The difficulty is indiagnosing the cause of the headache so that the appropriatetreatment is provided, or if referral to a specialist is therecommended course of action. The ABC of Headache helps with this dilemma and guidesthe healthcare professional to look for the possible causes ofpresenting symptoms. Based on real case histories, each chapterguides the reader from symptoms through to diagnosis andmanagement. This new ABC is a highly illustrated, informative, andpractical source of knowledge. With links to further informationand resources, it is a valuable text for healthcare professionalsat all levels of practice and training.

Refractory Migraine

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Author : Elliot A. Schulman, FACP, MD
Publisher : Oxford University Press
ISBN 13 : 0199745560
Total Pages : 495 pages
Book Rating : 4.1/5 (997 download)

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Book Synopsis Refractory Migraine by : Elliot A. Schulman, FACP, MD

Download or read book Refractory Migraine written by Elliot A. Schulman, FACP, MD and published by Oxford University Press. This book was released on 2010-08-05 with total page 495 pages. Available in PDF, EPUB and Kindle. Book excerpt: A must-have book for any health professional who treats patients with headache disorders, Refractory Migraine is written by international experts from the world's top headache centers. It describes how they approach the treatment of migraine patients who continue to suffer despite appropriate medical treatment. First, it highlights current ideas about the definition and characterization of refractory migraine, and reviews underlying causes and contributing factors. Then, individual chapters cover every important aspect of migraine treatment with the focus entirely on refractory forms of the disorder. Its many features include detailed algorithms for outpatient and inpatient withdrawal from overused medications, innovative drug therapy and nonpharmacological treatments, a list of questions to ask before deciding to try hormonal therapies, and detailed descriptions of how to recognize and interact with patients who have challenging personality disorders or concomitant psychiatric problems. We're confident you'll often turn to this book for advice about challenges in migraine management. When you do, the bulleted lists and boxes that highlight and condense the main messages of each chapter put the information you need at your fingertips. If you treat patients with migraine, you will recognize many of the challenging situations and topics covered in this book - and you will be encouraged by the innovative and resourceful therapeutic strategies suggested by seasoned headache doctors with a wealth of clinical experience. Readable, comprehensive and up to date, this book gives you access to ingenious treatment approaches developed and refined in specialty headache clinics that regularly - and successfully - treat patients with refractory headache problems. When you meet the next migraine patient who says "I've tried it all, and nothing works", you will know where to go for practical advice about what to do next.

Management of Headache and Headache Medications

Author : Lawrence D. Robbins
Publisher : Springer Science & Business Media
ISBN 13 : 1461221242
Total Pages : 354 pages
Book Rating : 4.4/5 (612 download)

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Book Synopsis Management of Headache and Headache Medications by : Lawrence D. Robbins

Download or read book Management of Headache and Headache Medications written by Lawrence D. Robbins and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: With full revisions and updates, plus new chapters on herbs and vitamins, "triptans," headache during breast feeding, menstrual migraine, opiate abuse, cervicogenic causes of headache, and exercise and sexual headache, this book presents a full and in-depth range of information for primary care physicians and neurologists.

The Migraine Brain

Author : David Borsook
Publisher : Oxford University Press, USA
ISBN 13 : 019975456X
Total Pages : 400 pages
Book Rating : 4.1/5 (997 download)

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Book Synopsis The Migraine Brain by : David Borsook

Download or read book The Migraine Brain written by David Borsook and published by Oxford University Press, USA. This book was released on 2012-07-26 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Migraine Brain provides a general overview of the history of migraine, its pathophysiology, as well as in-depth details on the Clinical Perspectives and the different imaging techniques in use (MR, fMRI, DTI, VBM, PET, fMRI, and MEG). It also includes details on modulation of the brain using such techniques as TMS. The book concludes with a discussion of future uses of imaging in the diagnosis and treatment of migraines and other headaches.