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Recent Advances In Potential Biomarkers For Rheumatic Diseases And In Cell Based Therapies In The Management Of Inflammatory Rheumatic Diseases
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Book Synopsis Recent Advances in Potential Biomarkers for Rheumatic Diseases and in Cell-based Therapies in the Management of Inflammatory Rheumatic Diseases by : Eric Toussirot
Download or read book Recent Advances in Potential Biomarkers for Rheumatic Diseases and in Cell-based Therapies in the Management of Inflammatory Rheumatic Diseases written by Eric Toussirot and published by Frontiers Media SA. This book was released on 2022-02-18 with total page 347 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Autoimmune and Inflammatory Rheumatic Diseases: Identifying Biomarkers of Response to Therapy with Biologics by : Anna Lisa Giuliani
Download or read book Autoimmune and Inflammatory Rheumatic Diseases: Identifying Biomarkers of Response to Therapy with Biologics written by Anna Lisa Giuliani and published by Frontiers Media SA. This book was released on 2022-03-14 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Imaging In Inflammatory Rheumatic Diseases - Recent Advances by : Xenofon Baraliakos
Download or read book Imaging In Inflammatory Rheumatic Diseases - Recent Advances written by Xenofon Baraliakos and published by Frontiers Media SA. This book was released on 2022-02-02 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Modern Therapeutics in Rheumatic Diseases by : George C. Tsokos
Download or read book Modern Therapeutics in Rheumatic Diseases written by George C. Tsokos and published by Springer Science & Business Media. This book was released on 2001-11-08 with total page 648 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leading clinicians and clinical researchers discuss in practical detail the newest treatments used in rheumatic diseases, emphasizing-without neglecting current standard treatments-those experimental therapies now undergoing clinical trials and poised for early introduction into the rheumatology armamentarium. The diseases and therapeutic regimes examined here range from rheumatoid arthritis and its treatment by gene therapy, to osteoarthritis and systemic autoimune diseases. Each chapter is organized so that the busy clinician can quickly obtain all the information needed optimal patient treatment. This includes an analysis of the pathogenic mechanisms that explain the molecular basis of the newer therapeutics, reviews of animal data and the results of clinical trials, and recommendations concerning use, side effects, and precautions.
Book Synopsis New Therapies in the Field of Rheumatology by : Maria Gerosa
Download or read book New Therapies in the Field of Rheumatology written by Maria Gerosa and published by . This book was released on 2020 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, the long term prognosis of patients with rheumatic disease has dramatically improved, due to the enormous advances in the understanding of the pathogenesis of these diseases that have led to the development of drugs targeting the molecules directly involved in the inflammatory response. The development of these biological drugs has radically changed the therapeutic approach of inflammatory rheumatic diseases, mainly in patients resistant to standard treatment. Also in the field of conventional therapy, many new data have confirmed the effectiveness of "old" drugs, such as hydroxychloroquine, methotrexate and azathioprine, demonstrating several additional beneficial properties for the treatment of Systemic Lupus Erythematosus (SLE), Rheumatoid Arthritis (RA) or other autoimmune diseases. Moreover, immunosuppressant developed to prevent graft rejection such as mycophenolate or tacrolimus have been demonstrated to have an important role in the treatment of rheumatic patients. Beside the well defined anti-inflammatory properties of biological and synthetic anti-rheumatic drugs, a number of additional beneficial effects have been suggested, that have been hypothesized to prevent long term complications of autoimmune diseases, such as accelerated atherosclerosis, increased cardiovascular risk and osteoporosis. This Research Topic collects new information regarding safety and effectiveness of new and old drugs for the treatment of RA, SLE, or other autoimmune diseases.
Book Synopsis Rheumatology E-Book by : Marc C. Hochberg
Download or read book Rheumatology E-Book written by Marc C. Hochberg and published by Elsevier Health Sciences. This book was released on 2014-06-16 with total page 2046 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stay current in the ever-changing discipline of rheumatology with clear, reliable guidance from Hochberg’s Rheumatology, one of the most respected and trusted sources in the field. Designed to meet the needs of the practicing clinician, this medical reference book provides extensive, authoritative coverage of rheumatic diseases from basic scientific principles to practical points of clinical management in a lucid, logical, user-friendly manner. Track disease progression and treat patients more effectively with the information on genetic findings, imaging outcomes, cell and biologic therapies, rheumatoid arthritis, and SLE. Incorporate recent findings about pathogenesis of disease; imaging outcomes for specific diseases like RA, osteoarthritis, and spondyloarthropathies; cell and biologic therapies; and other timely topics. Remain up to date on the latest information in rheumatology through 13 brand-new chapters covering biomedical and translation science, disease and outcome assessment, new imaging modalities, early emerging disease, clinical therapeutics, patient management, and rehabilitation. Take advantage of expanded coverage of small molecule treatment, biologics, biomarkers, epigenetics, biosimilars, and cell-based therapies. Focus on the core knowledge needed for successful results with each chapter co-authored by an internationally-renowned specialist in the field. Easily find the information you need thanks to a consistent, user-friendly format with templated content and large-scale images.
Book Synopsis Clinical Innovation in Rheumatology by : Jason Liebowitz
Download or read book Clinical Innovation in Rheumatology written by Jason Liebowitz and published by CRC Press. This book was released on 2022-10-04 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tremendous advances have been made in the field of rheumatology, profoundly changing our understanding of many rheumatologic conditions and creating a new frontier for effective treatments. This book explains the most significant advances in research and care and speculates as to what will be the future of rheumatology over the next several decades, including challenges and lessons learned from past experiences in the field. It highlights landmark research articles and scientific discoveries, discusses how big data, personalized medicine, new biomarkers for disease, and other technological revolutions will shape the future, making it a must-have resource for physicians from all regions of the world. Key Features • Includes concise yet thorough description of the landmark studies and scientific breakthroughs coupled with easy-to-follow organizational structure of chapters that are accessible to readers at different levels of training. • Brings together world-leading experts to provide a fresh perspective to trainees such as residents and fellows-in-training, as well as more senior clinicians and researchers across the field of rheumatology and in specialties such as cardiology, dermatology, pulmonology, nephrology, and neurology, all of whom care for patients with rheumatologic conditions. • Allows the authors to imagine and speculate about the evolution of the field of rheumatology in the coming decades. Examples of such speculative possibilities include use of synovial biopsy to predict response to treatment in rheumatoid arthritis, replacement of renal biopsy with urinary proteomics in diagnosing and classifying lupus nephritis, use of new therapeutics to obviate the need for steroids in the treatment of ANCA-associated vasculitis, and the use of machine learning to evaluate subtle changes in imaging for management of inflammatory arthritis.
Book Synopsis Contemporary Targeted Therapies in Rheumatology by : Josef S. Smolen
Download or read book Contemporary Targeted Therapies in Rheumatology written by Josef S. Smolen and published by CRC Press. This book was released on 2007-10-18 with total page 636 pages. Available in PDF, EPUB and Kindle. Book excerpt: Targeted therapies of rheumatic diseases have become a reality and have completely changed patient care as well as patient expectations. Initial success with therapies aimed at blocking TNF and IL-1 has stimulated the development of additional targeted approaches focused on other cytokines as well as specific cells and pathways involved in the path
Download or read book Rheumatology written by Marc C. Hochberg and published by Saunders. This book was released on 2015 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stay current in the ever-changing discipline of rheumatology with clear, reliable guidance from Hochberg's Rheumatology, one of the most respected and trusted sources in the field. Designed to meet the needs of the practicing clinician, this medical reference book provides extensive, authoritative coverage of rheumatic diseases from basic scientific principles to practical points of clinical management in a lucid, logical, user-friendly manner. Track disease progression and treat patients more effectively with the information on genetic findings, imaging outcomes, cell and biologic therapies, rheumatoid arthritis, and SLE. Incorporate recent findings about pathogenesis of disease; imaging outcomes for specific diseases like RA, osteoarthritis, and spondyloarthropathies; cell and biologic therapies; and other timely topics. Remain up to date on the latest information in rheumatology through 13 brand-new chapters covering biomedical and translation science, disease and outcome assessment, new imaging modalities, early emerging disease, clinical therapeutics, patient management, and rehabilitation. Take advantage of expanded coverage of small molecule treatment, biologics, biomarkers, epigenetics, biosimilars, and cell-based therapies. Focus on the core knowledge needed for successful results with each chapter co-authored by an internationally-renowned specialist in the field. Easily find the information you need thanks to a consistent, user-friendly format with templated content and large-scale images. Access the full text online at Expert Consult. Fully revised, the new edition of the celebrated Hochberg is a must-have for every rheumatologist.
Book Synopsis Inflammation and Rheumatic Diseases by : Stefan Laufer
Download or read book Inflammation and Rheumatic Diseases written by Stefan Laufer and published by Georg Thieme Verlag. This book was released on 2003 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a useful guide for students, physicians in continuing education and practitioners who want to keep abreast of the latest developments in rheumatology. The chapters on the pathogenesis of rheumatoid arthritis and the biochemistry of inflammation present the latest research results in this field and are illustrated by a wealth of charts and tables. There follows practical and critical information on all drug groups that are currently used in the treatment of inflammatory rheumatic diseases and osteoarthritis. (Midwest).
Book Synopsis Insights in Inflammation: 2022 by : Pietro Ghezzi
Download or read book Insights in Inflammation: 2022 written by Pietro Ghezzi and published by Frontiers Media SA. This book was released on 2023-06-27 with total page 185 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Cancer and Rheumatic Diseases, An Issue of Rheumatic Disease Clinics of North America, E-Book by : John Davis
Download or read book Cancer and Rheumatic Diseases, An Issue of Rheumatic Disease Clinics of North America, E-Book written by John Davis and published by Elsevier Health Sciences. This book was released on 2020-08-03 with total page 209 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Rheumatic Disease Clinics, guest edited by Dr. John Davis, will discuss Cancer and Rheumatic Diseases. This issue is one of four selected each year by series Consulting Editor, Dr. Michael Weisman. Topics discussed in this issue include, but are not limited to: rheumatic drugs and malignancy potential, biologic drugs and cancer, methotrexate and cancer, managing rheumatoid arthritis with cancer, Sjogren's Syndrome and cancer, lupus and cancer, scleroderma and cancer, cancer and spondylarthritis, and cancer immunotherapy.
Book Synopsis New Developments in the Pathogenesis of Rheumatoid Arthritis by : Lazaros Sakkas
Download or read book New Developments in the Pathogenesis of Rheumatoid Arthritis written by Lazaros Sakkas and published by BoD – Books on Demand. This book was released on 2017-02-22 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt: The pathogenesis of rheumatoid arthritis (RA) is incompletely understood. HLA class II alleles and T cells have been implicated for many years. The discovery of anticitrullinated peptide antibodies (ACPAs), along with the effectiveness of biological treatments targeting cytokines, such as TNF-?, IL-6, and also T cells and B cells, reinforced the pathogenetic role of the respective factors. ACPAs, induced by cigarette smoking and periodontitis in individuals with HLA-DRB1 shared epitope, appear to be autoantigens that initiate the inflammatory immune response in RA. MicroRNAs, part of epigenetic mechanisms, which also include DNA methylation, and histone modification, as well as microbiota, the composition of microbes in body cavities, also appear to influence arthritis and are discussed in this book.
Book Synopsis Rheumatic Diseases and Syndromes Induced by Cancer Immunotherapy by : Maria E. Suarez-Almazor
Download or read book Rheumatic Diseases and Syndromes Induced by Cancer Immunotherapy written by Maria E. Suarez-Almazor and published by Springer Nature. This book was released on 2021-02-16 with total page 363 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the increasing use of immune checkpoint inhibitors (ICI) across various cancers, the trends for indication at earlier stages, and the use of combination immunotherapy, the frequency of ICI-induced immune-related adverse events (irAE) is expected to grow substantially. Management of these irAE is challenging as it requires not only consideration of the toxicity but also risk-benefit ratios with respect to the primary cancer. Several rheumatic irAE have been reported with ICI therapy including arthritis, myositis, polymyalgia-like syndromes, sicca/Sjogren-like manifestations, and several other less common systemic autoimmune features commonly associated with connective tissue disease. This handbook provides clinicians with a comprehensive overview of the management of rheumatic irAE that develop from cancer immunotherapy. It focuses on the irAE seen with ICI, the most frequently used agents in treating cancer. It provides an overview of cancer immunology, immunotoxicity, and immunotherapies such as ICI, cytokine-based therapy, and CART. It examines the epidemiology, clinical manifestations, diagnosis, differential diagnosis, and treatment of a variety of rheumatic immune-related adverse events arising from these therapies. Chapters also cover cancer immunotherapy in patients with preexisting rheumatic diseases such as inflammatory arthritis and other connective tissue disorders. The book helps clinicians to distinguish the current types of cancer immunotherapy and general toxicity patterns, recognize and diagnose rheumatic clinical syndromes, understand the pathogenesis of irAE, and consider risk–benefit ratios when managing patients with rheumatic irAE. Rheumatic Diseases and Syndromes Induced by Cancer Immunotherapy is an essential resource for physicians and related professionals, residents, fellows, graduate students and nurses alike in rheumatology, clinical immunology, oncology, and internal medicine.
Book Synopsis The Microbiome in Rheumatic Diseases and Infection by : Gaafar Ragab
Download or read book The Microbiome in Rheumatic Diseases and Infection written by Gaafar Ragab and published by Springer. This book was released on 2018-06-19 with total page 489 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses the role of the microbiome in rheumatic diseases and details its implications for patient treatment. Recently, with technological advances, there has been significant research into the microbiome. This has enabled us to more profoundly understand its role in our immune system maturation as well as the role played by microorganisms in autoimmunity and the deeply related rheumatic diseases. This book comprehensively explains the emerging microbiome research through the interrelationships of biomedical sciences, including: immunology, microbiology, bioinformatics, and, with special emphasis, the clinical aspect of rheumatology. It examines the interplay between infectious organisms and major autoimmune diseases, including rheumatoid arthritis, psoriatic arthritis, juvenile arthritis, systemic lupus erythematosus, and vasculitis, and explains how to apply that knowledge to diagnostic techniques and treatment decisions. The international team of expert authors provides insight into current therapies and future interventions specifically targeting the microbiota and explores the impact of our deeper understanding on enhancing personalized medicine. The Microbiome in Rheumatic Diseases and Infection is an essential resource for rheumatologists, pediatricians, internists, microbiologists, and critical care providers caring for children and adults with rheumatic diseases.
Book Synopsis Biologics for the Treatment of Rheumatoid Arthritis by : Ronald van Vollenhoven
Download or read book Biologics for the Treatment of Rheumatoid Arthritis written by Ronald van Vollenhoven and published by Springer. This book was released on 2015-12-22 with total page 139 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of the available biologic therapies whilst comparing them to standard disease modifying anti-rheumatic drugs, and discusses how best to determine which therapy is most appropriate for an individual patient in the framework of current guidelines. Biologics for the Treatment of Rheumatoid Arthritis is an up-to-date and concise practical guide to the latest therapeutic developments in this field. This book is an invaluable source of topical information for all rheumatologists and health care professionals treating patients with rheumatoid arthritis.
Book Synopsis Preclinical Rheumatic Disease, An Issue of Rheumatic Disease Clinics by : Vivian P. Bykerk
Download or read book Preclinical Rheumatic Disease, An Issue of Rheumatic Disease Clinics written by Vivian P. Bykerk and published by Elsevier Health Sciences. This book was released on 2014-11-20 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: The ability to intervene at the earliest phases in the pathogenesis of a chronic rheumatic disease caused by auto-inflammatory, autoimmune, or tissue injury mechanisms has th epotential to prevent disease manifestations and consequences, limited loss of quality of life, comorbidity, and costs to society. This issue is dedicated to exploring the stages of rheumatic disease, biologic mechanisms contributing to the pathogenesis along with possible ways to study and screen for persons at risk with the ultimate goal of finding ways to prevent these devastating diseases.
