Recent Advances In Leukemia And Lymphoma

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Advances in Lymphoma Research

Author : Fernando Cabanillas
Publisher : Springer Science & Business Media
ISBN 13 : 1461541298
Total Pages : 239 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Advances in Lymphoma Research by : Fernando Cabanillas

Download or read book Advances in Lymphoma Research written by Fernando Cabanillas and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fernando Cabanillas In 1993, Fisher et al. published the results of a randomized trial comparing three third-generation regimens against the classic CHOP combination. For several years, the oncology community had been convinced that the third generation regimens were clearly superior to CHOP. It came as a shock to many that there was no difference in outcome between the four arms of this clinical trial. The logical conclusion is that CHOP is as good as any of the other regimens tested in that study. Unfortunately, this excellent study has been misinterpreted by many as proving that there has not been any progress in the field of lymphoma during the last 20 years. Furthermore, it has led to a fatalistic attitude in the reasoning of many clinicians who feel that 'nothing works better than CHOP' and therefore that it is not worth testing new drugs or developing novel regimens. However, the process by which we move forward in the oncology field is seldom by dramatic breakthroughs. Frequently, what appears at first glance to be a breakthrough turns out later to be just a modest step forward. Several steps forward eventually add up to a major advance, but this advance goes unnoticed because of the slow nature of the process. In this volume, we have chosen to discuss several of these steps, which we feel are clearly making a positive impact on the field of lymphomas and which soon should make a major difference in therapeutic results.

Recent Advances in Leukemia and Lymphoma

Author : Robert Peter Gale
Publisher : Wiley-Liss
ISBN 13 : 9780471602569
Total Pages : 620 pages
Book Rating : 4.6/5 (25 download)

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Book Synopsis Recent Advances in Leukemia and Lymphoma by : Robert Peter Gale

Download or read book Recent Advances in Leukemia and Lymphoma written by Robert Peter Gale and published by Wiley-Liss. This book was released on 1987-01-01 with total page 620 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Trends in Leukemia Research

Author : Rafael M. Romero
Publisher : Nova Publishers
ISBN 13 : 9781594543111
Total Pages : 218 pages
Book Rating : 4.5/5 (431 download)

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Book Synopsis Trends in Leukemia Research by : Rafael M. Romero

Download or read book Trends in Leukemia Research written by Rafael M. Romero and published by Nova Publishers. This book was released on 2005 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new book brings together leading research from around the globe. Leukaemia is a cancer that begins in blood cells. In people with leukaemia, the bone marrow produces abnormal white blood cells. The abnormal cells are leukaemia cells. At first, leukaemia cells function almost normally. In time, they may crowd out normal white blood cells, red blood cells, and platelets. The scope of the book includes the four common types of leukaemia: Chronic lymphocytic leukaemia (chronic lymphoblastic leukaemia, CLL) most often affecting people over age 55. Chronic myeloid leukaemia (chronic myelogenous leukaemia, CML) affects mainly adults. Acute lymphocytic leukaemia (acute lymphoblastic leukaemia, ALL) the most common type of leukaemia in young children. Acute myeloid leukaemia (acute myelogenous leukaemia, AML) which occurs in both adults and children. New advances in diagnosis, pathogenesis and therapy are presented.

Recent Advances in Leukemia and Lymphoma

Author : David W. Golde
Publisher : Alan R. Liss
ISBN 13 :
Total Pages : 632 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Recent Advances in Leukemia and Lymphoma by : David W. Golde

Download or read book Recent Advances in Leukemia and Lymphoma written by David W. Golde and published by Alan R. Liss. This book was released on 1987 with total page 632 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Focus on Leukemia Research

Author : Rafael M. Romero
Publisher : Nova Publishers
ISBN 13 : 9781594540936
Total Pages : 206 pages
Book Rating : 4.5/5 (49 download)

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Book Synopsis Focus on Leukemia Research by : Rafael M. Romero

Download or read book Focus on Leukemia Research written by Rafael M. Romero and published by Nova Publishers. This book was released on 2004 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new book brings together leading research from around the globe. Leukaemia is cancer that begins in blood cells. In people with leukaemia, the bone marrow produces abnormal white blood cells. The abnormal cells are leukaemia cells. At first, leukaemia cells function almost normally. In time, they may crowd out normal white blood cells, red blood cells, and platelets. The scope of the book includes the four common types of leukaemia: chronic lymphocytic leukaemia (chronic lymphoblastic leukaemia, CLL) - most often affecting people over age 55; chronic myeloid leukaemia (chronic myelogenous leukaemia, CML) - affects mainly adults; acute lymphocytic leukaemia (acute lymphoblastic leukaemia, ALL) - the most common type of leukaemia in young children; and acute myeloid leukaemia (acute myelogenous leukaemia, AML) - which occurs in both adults and children. New advances in diagnosis, pathogenesis and therapy are also presented.

Diagnostic and Therapeutic Advances in Hematologic Malignancies

Author : Martin S. Tallman
Publisher : Springer Science & Business Media
ISBN 13 : 0585385718
Total Pages : 383 pages
Book Rating : 4.5/5 (853 download)

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Book Synopsis Diagnostic and Therapeutic Advances in Hematologic Malignancies by : Martin S. Tallman

Download or read book Diagnostic and Therapeutic Advances in Hematologic Malignancies written by Martin S. Tallman and published by Springer Science & Business Media. This book was released on 2007-11-23 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is no field of medicine in which advances in therapy have been so closely linked to a better understanding of molecular medicine than in the area of hematologic malignancies. Diagnostic and Therapeutic Advances in Hematologic Malignancies will provide practitioners and academic clinicians with a better understanding of the constant evolving concepts in this area.

Childhood Acute Lymphoblastic Leukemia

Author : Ajay Vora
Publisher : Springer
ISBN 13 : 3319397087
Total Pages : 342 pages
Book Rating : 4.3/5 (193 download)

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Book Synopsis Childhood Acute Lymphoblastic Leukemia by : Ajay Vora

Download or read book Childhood Acute Lymphoblastic Leukemia written by Ajay Vora and published by Springer. This book was released on 2017-04-21 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive and up-to-date review of all aspects of childhood Acute Lymphoblastic Leukemia, from basic biology to supportive care. It offers new insights into the genetic pre-disposition to the condition and discusses how response to early therapy and its basic biology are utilized to develop new prognostic stratification systems and target therapy. Readers will learn about current treatment and outcomes, such as immunotherapy and targeted therapy approaches. Supportive care and management of the condition in resource poor countries are also discussed in detail. This is an indispensable guide for research and laboratory scientists, pediatric hematologists as well as specialist nurses involved in the care of childhood leukemia.

Leukemia: Advances in Research and Treatment

Author : Emil J. Freireich
Publisher : Springer Science & Business Media
ISBN 13 : 9780792319672
Total Pages : 360 pages
Book Rating : 4.3/5 (196 download)

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Book Synopsis Leukemia: Advances in Research and Treatment by : Emil J. Freireich

Download or read book Leukemia: Advances in Research and Treatment written by Emil J. Freireich and published by Springer Science & Business Media. This book was released on 1993-03-31 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leukemia continues to offer the scientist a unique opportunity to gain new knowledge about the malignant transformation. As a result, this multi-authored volume, devoted to advances which have occurred over the last seven years, provides the reader with an important new understanding of leukemia, but perhaps even more important, predicts analogous, new developments in the other malignant diagnoses. In this respect, this volume represents the cutting edge of cancer research. This text is unique in that it includes in a single volume the leading contributors to their respective fields covering what the editors feel are the major advances in our knowledge of the biology and therapy of leukemia over the last seven years.

Pathology and Genetics of Tumours of Haematopoietic and Lymphoid Tissues

Author : World Health Organization
Publisher : IARC
ISBN 13 : 9789283224112
Total Pages : 360 pages
Book Rating : 4.2/5 (241 download)

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Book Synopsis Pathology and Genetics of Tumours of Haematopoietic and Lymphoid Tissues by : World Health Organization

Download or read book Pathology and Genetics of Tumours of Haematopoietic and Lymphoid Tissues written by World Health Organization and published by IARC. This book was released on 2001 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the third volume in the new World Health Organization series on histological and genetic typing of tumours. Tumours of the haematopoietic and lymphoid tissues are covered. This was a collaborative project of the European Association for Haematolpathology and the Society for Haematopathology and others. The WHO classification is based on the principles defined in the Revised European-American Classification of Lymphoid Neoplasms (REAL) classification. Over 50 pathologists from around the world were involved in the project and proponents of all major lymphoma and leukaemia classifications have agreed to accept the WHO as the standard classification of haematological malignancies. So this classification represents the first true world wide concensus of haematologic malignancies. Colour photographs, magnetic resonance and ultrasound images and CT scans are included.

Allogeneic Stem Cell Transplantation

Author : Hillard M. Lazarus
Publisher : Springer Science & Business Media
ISBN 13 : 1597454788
Total Pages : 885 pages
Book Rating : 4.5/5 (974 download)

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Book Synopsis Allogeneic Stem Cell Transplantation by : Hillard M. Lazarus

Download or read book Allogeneic Stem Cell Transplantation written by Hillard M. Lazarus and published by Springer Science & Business Media. This book was released on 2010-03-02 with total page 885 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the original publication of Allogeneic Stem Cell Transplantation: Clinical Research and Practice, Allogeneic hematopoietic stem cell transplantation (HSC) has undergone several fast-paced changes. In this second edition, the editors have focused on topics relevant to evolving knowledge in the field in order to better guide clinicians in decision-making and management of their patients, as well as help lead laboratory investigators in new directions emanating from clinical observations. Some of the most respected clinicians and scientists in this discipline have responded to the recent advances in the field by providing state-of-the-art discussions addressing these topics in the second edition. The text covers the scope of human genomic variation, the methods of HLA typing and interpretation of high-resolution HLA results. Comprehensive and up-to-date, Allogeneic Stem Cell Transplantation: Clinical Research and Practice, Second Edition offers concise advice on today's best clinical practice and will be of significant benefit to all clinicians and researchers in allogeneic HSC transplantation.

Clinical Management of Acute Lymphoblastic Leukemia

Author : Mark R. Litzow
Publisher : Springer Nature
ISBN 13 : 3030851478
Total Pages : 439 pages
Book Rating : 4.0/5 (38 download)

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Book Synopsis Clinical Management of Acute Lymphoblastic Leukemia by : Mark R. Litzow

Download or read book Clinical Management of Acute Lymphoblastic Leukemia written by Mark R. Litzow and published by Springer Nature. This book was released on 2022-01-01 with total page 439 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a state-of-the-art overview of acute lymphoblastic leukemia (ALL). The first section of the book presents the translational science behind ALL, reviewing molecular pathways and targets in B- and T-cell ALL, as well as techniques and application of minimal residual disease testing. The second section spotlights ALL management strategies for patients across the spectrum, from infants to the elderly. The final section outlines current and new advances in ALL treatment, including new monoclonal antibodies and allogenic and autologous HSCT. Written by experts in the field, Clinical Management of Acute Lymphoblastic Leukemia: From Bench to Bedside is a valuable resource that will guide patient management, stimulate investigative efforts, and increase understanding of the biologic underpinnings of the disease.

Current Concepts in the Management of Lymphoma and Leukemia

Author : J.E. Ultmann
Publisher : Springer Science & Business Media
ISBN 13 : 3642462596
Total Pages : 326 pages
Book Rating : 4.6/5 (424 download)

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Book Synopsis Current Concepts in the Management of Lymphoma and Leukemia by : J.E. Ultmann

Download or read book Current Concepts in the Management of Lymphoma and Leukemia written by J.E. Ultmann and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume summarizes the Proceedings of the fourth biennial Cancer Teaching Symposium held on March 7 and 8, 1970, at the University of Chicago Pritzker School of Medicine. The program was prepared by Drs. LAWRENCE ALLEN, MELVIN GRIEM, WERNER KIRSTEN, LEON JACOBSON, JOHN ULTMANN, ROBERT WISSLER, and STANLEY Y ACHNIN. The purpose of the Symposium was to present current advances in the area of lymphoma and leukemia to the staff and students of this medical center and to students and interested physicians from other institutions in the Chicago area. Like the other teaching symposia held in 1964, 1966, and 1968, this Symposium attracted over 450 physicians and scientists. In the course of one and a half days the audience had the opportunity to listen to the twenty-four invited speakers and to lively discussions. The formal presentations as well as discussions are recorded in these pages. This Teaching Symposium could not have been undertaken without the faithful assistance of the Program Committee, the Cancer Training Grant Advisory Com mittee, the staff who recorded and transcribed the Proceedings, and the editorial assistants. We wish to thank the following for their efforts: DOROTHY A. WILLIS, Administrative Secretary for Institutional Cancer Training Grant, Dr. ROBERT L. HUNTER, Dr. ROBERT H. KIRSCHNER, Dr. ROBERT A. ORLANDO, Dr. STEPHEN STRUM, RANDOLPH HUGHES, JULIA KANT, GEORGIA MOHR, TERRY PEARSON, FRIEDA RANNEY, and CAROL REESE. This Symposium received financial support from the Cancer Training Program Tt2 CA 08077-04 and The Chicago Tumor Institute.

Hematology

Author : Margarita Guenova
Publisher : BoD – Books on Demand
ISBN 13 : 178923350X
Total Pages : 212 pages
Book Rating : 4.7/5 (892 download)

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Book Synopsis Hematology by : Margarita Guenova

Download or read book Hematology written by Margarita Guenova and published by BoD – Books on Demand. This book was released on 2018-06-27 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hematology has constantly been advancing in parallel with technological developments that have expanded our understanding of the phenotypic, genetic, and molecular complexity and extreme clinical and biological heterogeneity of blood diseases. This has in turn allowed for developing more effective and less toxic alternative therapeutic approaches directed against critical molecular pathways. The continuous and rather extensive influx of new information regarding the key features and underlying mechanisms as well as treatment options in hematology requires a frequent update of this topic. The primary objective of this book is to provide the specialists involved in the clinical management and experimental research in hematological diseases with comprehensive and concise information on some important theoretical and practical developments in the biology, clinical assessment, and treatment of patients, as well as on some molecular and pathogenetic mechanisms and the respective translation into novel therapies.

Leukemia and Lymphoma

Author : Michael G. Kharas
Publisher :
ISBN 13 : 9781621823063
Total Pages : pages
Book Rating : 4.8/5 (23 download)

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Book Synopsis Leukemia and Lymphoma by : Michael G. Kharas

Download or read book Leukemia and Lymphoma written by Michael G. Kharas and published by . This book was released on 2020 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: "Leukemia and lymphoma are cancers that affect cells of the blood. This book examines the genetic and epigenetic changes in blood cells that lead to these conditions and current treatment strategies"--

Recent Advances in Cell Biology of Acute Leukemia

Author : Wolf-Dieter Ludwig
Publisher : Springer
ISBN 13 : 9783642848971
Total Pages : 0 pages
Book Rating : 4.8/5 (489 download)

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Book Synopsis Recent Advances in Cell Biology of Acute Leukemia by : Wolf-Dieter Ludwig

Download or read book Recent Advances in Cell Biology of Acute Leukemia written by Wolf-Dieter Ludwig and published by Springer. This book was released on 2012-02-09 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The development of new techniques such as immuno phenotyping, cytogenetic investigations and, more recently, molecular studies has considerably increased our diagnostic repertoire and broadened our ideas about the biology of acute leukemias. While immunophenotyping with mono clonal antibodies has yielded increased diagnostic precision and made it possible to develop a highly reproducible classification of acute leukemias based on cell-biological features, further insights have been gained into the patho genetic mechanisms involved in leukemogenesis by means of cytogenetic detection of acquired structural chromosomal abnormalities. Analysis of the leukemia-associated chromo somal breakpoints using molecular techniques can now pinpoint many genomic sites essential for normal develop ment and maturation of hematopoietic cells but functionally disrupted in leukemic cells. The main goal of the international workshop that we held in Berlin with a select group of scientists and clinicians involved in leukemia research was to describe the state of the art and new developments in the immunologic, cytogenetic, and molecular characterization of acute leukemias and to discuss the clinical importance of cell biological features. After introductory survey lectures dealing with the immunological and molecular-biological characteristics of normal vs. malignant lymphatic and myeloid progenitor cells, the workshop centered on con tributions characterizing the immunophenotype and both numerical and structural chromosomal abnormalities in acute leukemias.

Chronic Lymphocytic Leukemia

Author :
Publisher :
ISBN 13 :
Total Pages : 48 pages
Book Rating : 4.:/5 (98 download)

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Book Synopsis Chronic Lymphocytic Leukemia by :

Download or read book Chronic Lymphocytic Leukemia written by and published by . This book was released on 2015 with total page 48 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Treatment of Leukemia and Lymphoma

Author : David A. Scheinberg
Publisher : Elsevier
ISBN 13 : 0080490409
Total Pages : 417 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Treatment of Leukemia and Lymphoma by : David A. Scheinberg

Download or read book Treatment of Leukemia and Lymphoma written by David A. Scheinberg and published by Elsevier. This book was released on 2004-10-30 with total page 417 pages. Available in PDF, EPUB and Kindle. Book excerpt: New Treatments of Leukemia and Lymphoma describes the most important advances in the therapy of hematopoietic cancers that have been derived from recent discoveries in cancer cell biology, kinase biochemistry, and immunology. Detailed descriptions of the large number of new and effective agents that have recently become available for the treatment of leukemias and lymphomas as well as an understanding of their mechanisms of action and their integration into current therapy are provided. A number of experimental drug reagents currently in clinical investigation are also discussed. The therapies include conventional anti-metabolites, monoclonal antibodies directed to cell surface receptors, antibodies tagged with toxins and radiopharmaceuticals, inhibitors of specific kinases, stem cell transplants, and engineered T-cells designed to selectively target hematopoietic cancers. The contents of the book will allow practitioners and investigators alike to understand what is current and state of the art as well as what to look for in the future. * Provides an up-to-date, state of the art discussion of a rapidly changing field * Great breadth covering conventional chemotherapeutic agents, biologic agents such as antibodies, novel small molecule inhibitors and genetically engineered cells * Written by international experts in each of the fields