Rearrangements With Migration To Electrophilic Heteroatomic Centers

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Rearrangements with Migration to Electrophilic Heteroatomic Centers

Author : Sosale Chandrasekhar
Publisher : Elsevier
ISBN 13 : 0128237449
Total Pages : 284 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Rearrangements with Migration to Electrophilic Heteroatomic Centers by : Sosale Chandrasekhar

Download or read book Rearrangements with Migration to Electrophilic Heteroatomic Centers written by Sosale Chandrasekhar and published by Elsevier. This book was released on 2024-10-09 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rearrangements with Migration to Electrophilic Heteroatomic Centers: Timeless Classics in Organic Synthesis covers the basic principles and synthetic applications of a critically important class of organic reactions that date back to the founding period of organic chemistry. These reactions are not only of historical and pedagogical interest, but also have great practical value to this day, being inevitable in any strategy concerning the introduction of nitrogen and oxygen functionality. The book is made up of three parts, dealing with the Beckmann reaction, the Hoffmann family of reactions and the Baeyer-Villiger reaction.The book strikes a balance between delineation and exhaustiveness, with up-to-date refences for readers requiring in-depth coverage. Relevant industrial applications, including pharmaceutical processes, are included. - Summarizes mechanistic background with an emphasis on synthetic applications - Includes up-to-date references that allow for locating original papers for experimental procedures - Provides applications in the synthesis of complex molecules and natural products to judge the scope and limitations of each reaction

Modern Physical Organic Chemistry

Author : Eric V. Anslyn
Publisher : University Science Books
ISBN 13 : 9781891389313
Total Pages : 1148 pages
Book Rating : 4.3/5 (893 download)

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Book Synopsis Modern Physical Organic Chemistry by : Eric V. Anslyn

Download or read book Modern Physical Organic Chemistry written by Eric V. Anslyn and published by University Science Books. This book was released on 2006 with total page 1148 pages. Available in PDF, EPUB and Kindle. Book excerpt: In additionto covering thoroughly the core areas of physical organic chemistry -structure and mechanism - this book will escortthe practitioner of organic chemistry into a field that has been thoroughlyupdated.

Organic Reactions, Volume 102

Author :
Publisher : John Wiley & Sons
ISBN 13 : 1119651220
Total Pages : 990 pages
Book Rating : 4.1/5 (196 download)

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Book Synopsis Organic Reactions, Volume 102 by :

Download or read book Organic Reactions, Volume 102 written by and published by John Wiley & Sons. This book was released on 2020-07-08 with total page 990 pages. Available in PDF, EPUB and Kindle. Book excerpt: Band 102 dieser Reihe für Organische Chemiker in Wissenschaft und Industrie präsentiert eine kritische Auseinandersetzung mit weit verbreiteten organischen Reaktionen oder bestimmten Phasen einer Reaktion. Betrachtet werden die notwendigen Vorbereitungen. Der Schwerpunkt liegt dabei auf Einschränkungen, Störeinflüssen, Struktureffekten und der Auswahl experimenteller Verfahren. Das Fachbuch beinhaltet Tabellen, die alle möglichen Beispiele für die jeweilige Reaktion beschreiben. Detaillierte Prozeduren zeigen wichtige Modifikationen jeder Methode.

Comprehensive Organic Functional Group Transformations II

Author :
Publisher : Elsevier
ISBN 13 : 0080523471
Total Pages : 9196 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Comprehensive Organic Functional Group Transformations II by :

Download or read book Comprehensive Organic Functional Group Transformations II written by and published by Elsevier. This book was released on 2004-12-16 with total page 9196 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive Organic Functional Group Transformations II (COFGT-II) will provide the first point of entry to the literature for all scientists interested in chemical transformations. Presenting the vast subject of organic synthesis in terms of the introduction and interconversion of all known functional groups, COFGT-II provides a unique information source documenting all methods of efficiently performing a particular transformation. Organised by the functional group formed, COFGT-II consists of 144 specialist reviews, written by leading scientists who evaluate and summarise the methods available for each functional group transformation. Also available online via ScienceDirect – featuring extensive browsing, searching, and internal cross-referencing between articles in the work, plus dynamic linking to journal articles and abstract databases, making navigation flexible and easy. For more information, pricing options and availability visit www.info.sciencedirect.com. By systematically treating each functional group in turn the work also identifies what is not known, thus pointing the way to new research areas Follows the systematic layout of the successful 1995 COFGT reference work, based on the arrangement and bonding of hetero-atoms around a central carbon atom The work will save researchers valuable time in their research as each chapter is written by experts who have critically read and reviewed the literature and presented the best methods of forming every known functional group

Advances in Heterocyclic Chemistry

Author :
Publisher : Elsevier
ISBN 13 : 0080493564
Total Pages : 335 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Advances in Heterocyclic Chemistry by :

Download or read book Advances in Heterocyclic Chemistry written by and published by Elsevier. This book was released on 2000-07-04 with total page 335 pages. Available in PDF, EPUB and Kindle. Book excerpt: Established in 1960, Advances in Heterocyclic Chemistry is the definitive serial in the area--one of great importance to organic chemists, polymer chemists, and many biological scientists. Written by established authorities in the field, the comprehensive reviews combine descriptive chemistry and mechanistic insight and yield an understanding of how the chemistry drives the properties.

Studies in Natural Products Chemistry

Author : Shazia Anjum
Publisher : Elsevier Inc. Chapters
ISBN 13 : 0128084685
Total Pages : 29 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Studies in Natural Products Chemistry by : Shazia Anjum

Download or read book Studies in Natural Products Chemistry written by Shazia Anjum and published by Elsevier Inc. Chapters. This book was released on 2013-06-25 with total page 29 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular rearrangements occupy center stage in the development of organic synthesis and, consequently, in the impressive achievements that have resulted in the total synthesis of many complex natural products in the last decades. The purpose of this chapter, in this volume of a book series dedicated to the Studies in Natural Product Chemistry, is to show a set of selected and organized molecular rearrangements based on a personal choice of expertise related to the synthesis of complex bioactive molecules. Our selection addresses [3,3]-sigmatropic rearrangements, which continue to provide excellent opportunities for reaching high chemical diversity, operating in efficient synthetic schemes. [3,3]-Sigmatropic rearrangements, such as the Cope and Claisen rearrangements, are among the most basic and useful transformations in synthetic organic chemistry. This is possibly due to the fact that these rearrangements are efficient methods for the synthesis of quaternary, sterically hindered chiral centers, and for the stereoselective formation of carbon–carbon and carbon–heteroatom bonds. In addition, [3,3]-sigmatropic rearrangements can be easily integrated in, and adapted to, cascade processes as a simple method to prepare complex molecules in atom-efficient reactions. Consequently, in the context of [3,3]-sigmatropic rearrangements, we focus on the transformations of propargylic esters, whose rearrangements, in different experimental conditions, have been largely exploited for the synthesis of interesting key and useful intermediates. The rearrangements can be promoted by protic acids, Lewis acids, and noble metals such as Pt, Au, or Cu salts, or complexes that have recently emerged as the most popular and potent electrophilic activators of alkynes toward a number of nucleophilic agents, under homogeneous conditions.

Silver Catalysis in Organic Synthesis, 2 Volume Set

Author : Chao-Jun Li
Publisher : John Wiley & Sons
ISBN 13 : 3527342818
Total Pages : 848 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Silver Catalysis in Organic Synthesis, 2 Volume Set by : Chao-Jun Li

Download or read book Silver Catalysis in Organic Synthesis, 2 Volume Set written by Chao-Jun Li and published by John Wiley & Sons. This book was released on 2019-04-29 with total page 848 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dieses Fachbuch untersucht systematisch die Leistungsfähigkeit der Silberkatalyse, behandelt neu entwickelte organische Reaktionen und den Reaktionsmechanismus. Der Schwerpunkt liegt auf den Eigenschaften und dem Vergleich der Vorteile diese Katalyse in der organischen Synthese.

Strategic Applications of Named Reactions in Organic Synthesis

Author : Laszlo Kurti
Publisher : Elsevier
ISBN 13 : 0080575412
Total Pages : 808 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Strategic Applications of Named Reactions in Organic Synthesis by : Laszlo Kurti

Download or read book Strategic Applications of Named Reactions in Organic Synthesis written by Laszlo Kurti and published by Elsevier. This book was released on 2005-04-29 with total page 808 pages. Available in PDF, EPUB and Kindle. Book excerpt: Kurti and Czako have produced an indispensable tool for specialists and non-specialists in organic chemistry. This innovative reference work includes 250 organic reactions and their strategic use in the synthesis of complex natural and unnatural products. Reactions are thoroughly discussed in a convenient, two-page layout--using full color. Its comprehensive coverage, superb organization, quality of presentation, and wealth of references, make this a necessity for every organic chemist. - The first reference work on named reactions to present colored schemes for easier understanding - 250 frequently used named reactions are presented in a convenient two-page layout with numerous examples - An opening list of abbreviations includes both structures and chemical names - Contains more than 10,000 references grouped by seminal papers, reviews, modifications, and theoretical works - Appendices list reactions in order of discovery, group by contemporary usage, and provide additional study tools - Extensive index quickly locates information using words found in text and drawings

Applied Organic Chemistry

Author : Surya K. De
Publisher : John Wiley & Sons
ISBN 13 : 3527347852
Total Pages : 856 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Applied Organic Chemistry by : Surya K. De

Download or read book Applied Organic Chemistry written by Surya K. De and published by John Wiley & Sons. This book was released on 2021-03-08 with total page 856 pages. Available in PDF, EPUB and Kindle. Book excerpt: An indispensable guide for all synthetic chemists who want to learn about the most relevant reactions and reagents employed to synthesize important heterocycles and drugs! The synthesis of natural products, bioactive compounds, pharmaceuticals, and drugs is of fundamental interest in modern organic chemistry. New reagents and reaction methods towards these molecules are being constantly developed. By understanding the mechanisms involved and scope and limitations of each reaction applied, organic chemists can further improve existing reaction protocols and develop novel efficient synthetic routes towards frequently used drugs, such as Aspirin or Penicillin. Applied Organic Chemistry provides a summary of important (name) reactions and reagents applied in modern organic chemistry and drug synthesis. It covers rearrangement, condensation, olefination, metathesis, aromatic electrophilic substitutions, Pd-catalyzed C-C bond forming reactions, multi-component reactions, as well as oxidations and reductions. Each chapter is clearly structured, providing valuable information on reaction details, step-by-step mechanism, experimental procedures, applications, and (patent) references. By providing mechanistic information and representative experimental procedures, this book is an indispensable guide for researchers and professionals in organic chemistry, natural product synthesis, pharmaceutical, and medicinal chemistry, as well as post-graduates preparing themselves for a job in the pharmaceutical industry. Hot Topic: Reviews important classes of organic reactions (incl. name reactions) and reagents in medicinal chemistry. Useful: Provides information on reaction details, common reagents, and functional group transformations used to synthesize natural products, bioactive compounds, drugs, and pharmaceuticals, e.g. Aspirin, Penicillin. Unique: For every reaction the mechanism is explained step by step, and representative experimental procedures are given, unlike most books in this area. User-friendly: Chapters are clearly structured making it easy for the reader to compare different reactions. Applied Organic Chemistry is an indispensable guide for researchers and professionals in organic chemistry, natural product synthesis, pharmaceutical, and medicinal chemistry, as well as post-graduates preparing themselves for a job in the pharmaceutical industry.

Organic Syntheses Based on Name Reactions and Unnamed Reactions

Author : Alfred Hassner
Publisher : Elsevier
ISBN 13 : 1483287343
Total Pages : 462 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Organic Syntheses Based on Name Reactions and Unnamed Reactions by : Alfred Hassner

Download or read book Organic Syntheses Based on Name Reactions and Unnamed Reactions written by Alfred Hassner and published by Elsevier. This book was released on 2013-10-22 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synthetically useful organic reactions or reagents are often referred to by the name of the discoverer(s) or developer(s). Older name reactions are described in text books, but more recently developed synthetically useful reactions that may have been associated occasionally with a name are not always well known. For neither of the above are experimental procedures or references easy to find. In this monograph approximately 500 name reactions are included, of which over 200 represent newer name reactions and modern reagents. Each of these reactions are extremely useful for the contemporary organic chemistry researcher in industry or academic institutions. This book provides the information in an easily accessible form. In addition to seminal references and reviews, one or more examples for each name reaction are provided and a complete typical experimental procedure is included, to enable the student or researcher to immediately evaluate reaction conditions. Besides an alphabetical listing of reactions and reagents, cross references permit the organic practitioner to find those name reactions or reagents that enable specific transformations, such as, conversion of amines to nitriles, stereoselective reduction, fluoroalkylation, phenol alkynylation, asymmetric syntheses, allylic alkylation, nucleoside synthesis, cyclopentanation, hydrozirconation, to name a few. Emphasis has been placed on stereoselective and regioselective transformations as well as on enantioselective processes. The listing of reactions and reagents is supported by four indexes.

Dynamic Stereochemistry of Chiral Compounds

Author : Christian Wolf
Publisher : Royal Society of Chemistry
ISBN 13 : 0854042466
Total Pages : 534 pages
Book Rating : 4.8/5 (54 download)

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Book Synopsis Dynamic Stereochemistry of Chiral Compounds by : Christian Wolf

Download or read book Dynamic Stereochemistry of Chiral Compounds written by Christian Wolf and published by Royal Society of Chemistry. This book was released on 2008 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive overview of fundamental concepts of asymmetric synthesis along with in-depth discussion. Recent developments that address important synthetic challenges are presented and highlighted with hundreds of examples.

Studies in Natural Products Chemistry

Author :
Publisher : Newnes
ISBN 13 : 0444626328
Total Pages : 533 pages
Book Rating : 4.4/5 (446 download)

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Book Synopsis Studies in Natural Products Chemistry by :

Download or read book Studies in Natural Products Chemistry written by and published by Newnes. This book was released on 2013-06-25 with total page 533 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate and then determine the structures and biological activity of natural products rapidly, thus opening up exciting new opportunities in the field of new drug development to the pharmaceutical industry. The series also covers the synthesis or testing and recording of the medicinal properties of natural products. - Describes the chemistry of bioactive natural products - Contains contributions by leading authorities in the field - A valuable resource for natural products and medicinal chemistry

Target Organ Toxicity

Author : Gerald M. Cohen
Publisher : CRC Press
ISBN 13 : 1000694194
Total Pages : 243 pages
Book Rating : 4.0/5 (6 download)

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Book Synopsis Target Organ Toxicity by : Gerald M. Cohen

Download or read book Target Organ Toxicity written by Gerald M. Cohen and published by CRC Press. This book was released on 2019-07-17 with total page 243 pages. Available in PDF, EPUB and Kindle. Book excerpt: First published in 1986: The purpose of these volumes is to provide a valuable reference for established investigators and postgraduate students in toxicology.

Target Organ Toxicity, Volume I

Author : Gerald M. Cohen
Publisher : CRC Press
ISBN 13 : 1000722368
Total Pages : 246 pages
Book Rating : 4.0/5 (7 download)

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Book Synopsis Target Organ Toxicity, Volume I by : Gerald M. Cohen

Download or read book Target Organ Toxicity, Volume I written by Gerald M. Cohen and published by CRC Press. This book was released on 2020-01-29 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: This two-volume set provides essential information on the general princi-ples of target organ toxicity. Pharmacokinetics, metabolic activation and key defense mechanisms, excretion, species variation, and tissue-specific biochemistry are explored comprehensively. These general principles are then illustrated using specific examples of toxicity to different target organs and systems. DNA modifi-cation and repair in tumor induction, and specificity in tumor initiation are also examined. Of primary interest to toxicologist, pharma-cologists, biochemists, and environmental toxicologists.

Target Organ Toxicity

Author : Cohen
Publisher : CRC Press
ISBN 13 : 9780849357756
Total Pages : 246 pages
Book Rating : 4.3/5 (577 download)

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Book Synopsis Target Organ Toxicity by : Cohen

Download or read book Target Organ Toxicity written by Cohen and published by CRC Press. This book was released on 1986-08-31 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: This two-volume set provides essential information on the general princi-ples of target organ toxicity. Pharmacokinetics, metabolic activation and key defense mechanisms, excretion, species variation, and tissue-specific biochemistry are explored comprehensively. These general principles are then illustrated using specific examples of toxicity to different target organs and systems. DNA modifi-cation and repair in tumor induction, and specificity in tumor initiation are also examined. Of primary interest to toxicologist, pharma-cologists, biochemists, and environmental toxicologists.

Advanced Organic Chemistry

Author : Bernard Miller
Publisher :
ISBN 13 :
Total Pages : 360 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Advanced Organic Chemistry by : Bernard Miller

Download or read book Advanced Organic Chemistry written by Bernard Miller and published by . This book was released on 1998 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text covers the principles of mechanisms of organic reactions in a qualitative way and features a chapter on heterocyclic chemistry. End of chapter exercises feature references to current literature

The Art of Writing Reasonable Organic Reaction Mechanisms

Author : Robert B. Grossman
Publisher : Springer Science & Business Media
ISBN 13 : 0387954686
Total Pages : 371 pages
Book Rating : 4.3/5 (879 download)

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Book Synopsis The Art of Writing Reasonable Organic Reaction Mechanisms by : Robert B. Grossman

Download or read book The Art of Writing Reasonable Organic Reaction Mechanisms written by Robert B. Grossman and published by Springer Science & Business Media. This book was released on 2007-07-31 with total page 371 pages. Available in PDF, EPUB and Kindle. Book excerpt: Intended for students of intermediate organic chemistry, this text shows how to write a reasonable mechanism for an organic chemical transformation. The discussion is organized by types of mechanisms and the conditions under which the reaction is executed, rather than by the overall reaction as is the case in most textbooks. Each chapter discusses common mechanistic pathways and suggests practical tips for drawing them. Worked problems are included in the discussion of each mechanism, and "common error alerts" are scattered throughout the text to warn readers about pitfalls and misconceptions that bedevil students. Each chapter is capped by a large problem set.