Chronic Lymphocytic Leukemia

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Publisher : BoD – Books on Demand
ISBN 13 : 9533078812
Total Pages : 466 pages
Book Rating : 4.5/5 (33 download)

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Book Synopsis Chronic Lymphocytic Leukemia by : Pablo Oppezzo

Download or read book Chronic Lymphocytic Leukemia written by Pablo Oppezzo and published by BoD – Books on Demand. This book was released on 2012-02-10 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: B-cell chronic lymphocytic leukemia (CLL) is considered a single disease with extremely variable course, and survival rates ranging from months to decades. It is clear that clinical heterogeneity reflects biologic diversity with at least two major subtypes in terms of cellular proliferation, clinical aggressiveness and prognosis. As CLL progresses, abnormal hematopoiesis results in pancitopenia and decreased immunoglobulin production, followed by nonspecific symptoms such as fatigue or malaise. A cure is usually not possible, and delayed treatment (until symptoms develop) is aimed at lengthening life and decreasing symptoms. Researchers are playing a lead role in investigating CLL's cause and the role of genetics in the pathogenesis of this disorder. Research programs are dedicated towards understanding the basic mechanisms underlying CLL with the hope of improving treatment options.

The Chemistry of Ruthenium, Rhodium, Palladium, Osmium, Iridium and Platinum

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Publisher : Elsevier
ISBN 13 : 1483158403
Total Pages : 225 pages
Book Rating : 4.4/5 (831 download)

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Book Synopsis The Chemistry of Ruthenium, Rhodium, Palladium, Osmium, Iridium and Platinum by : Stanley E. Livingstone

Download or read book The Chemistry of Ruthenium, Rhodium, Palladium, Osmium, Iridium and Platinum written by Stanley E. Livingstone and published by Elsevier. This book was released on 2017-01-31 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Chemistry of Ruthenium, Rhodium, Palladium, Osmium, Iridium and Platinum

Book of Abstracts

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Publisher :
ISBN 13 :
Total Pages : 1328 pages
Book Rating : 4.:/5 (36 download)

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Book Synopsis Book of Abstracts by : American Chemical Society. Meeting

Download or read book Book of Abstracts written by American Chemical Society. Meeting and published by . This book was released on 1976 with total page 1328 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Comprehensive Coordination Chemistry II

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Publisher : Newnes
ISBN 13 : 0080913164
Total Pages : 11845 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Comprehensive Coordination Chemistry II by : J. A. McCleverty

Download or read book Comprehensive Coordination Chemistry II written by J. A. McCleverty and published by Newnes. This book was released on 2003-12-03 with total page 11845 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive Coordination Chemistry II (CCC II) is the sequel to what has become a classic in the field, Comprehensive Coordination Chemistry, published in 1987. CCC II builds on the first and surveys new developments authoritatively in over 200 newly comissioned chapters, with an emphasis on current trends in biology, materials science and other areas of contemporary scientific interest.

Routledge Course in Modern Mandarin Chinese Workbook 2 (Traditional)

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Publisher : Routledge
ISBN 13 : 1135871272
Total Pages : 385 pages
Book Rating : 4.1/5 (358 download)

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Book Synopsis Routledge Course in Modern Mandarin Chinese Workbook 2 (Traditional) by : Claudia Ross

Download or read book Routledge Course in Modern Mandarin Chinese Workbook 2 (Traditional) written by Claudia Ross and published by Routledge. This book was released on 2013-05-13 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Routledge Course in Mandarin Chinese is a two-year undergraduate course for students with no prior background in Chinese study. Designed to build a strong foundation in both the spoken and written language it develops all the basic skills such as pronunciation, character writing, word use and structures, while placing strong emphasis on the development of communicative skills. The complete course consists of Textbook Level 1, Workbook level 1 - including downloadable resources, Textbook level 2 and Workbook level 2 -including downloadable resources. All books are available separately in simplified as well as traditional characters and take the students from complete beginner to post-intermediate level. For more information about the course and additional resources, please visit the companion website at www.routledge.com/textbooks/9780415472517 Workbook Level 2 is designed to accompany Textbook Level 2 lesson by lesson, and offers exercises for homework, independent study and classroom use. The exercises focus on interpersonal, interpretative and presentational modes of communication while helping students to consolidate the vocabulary, characters, and structures introduced in each lesson. At the conclusion of this course, students will be able to read page-length texts for information, listen to and comprehend extended narratives on a variety of topics, and communicate a broad range of information orally and in writing. The course is also fully supported by an interactive companion website which contains a wealth of additional resources for both teachers and students. Teachers will find lesson plans in both English and Mandarin, providing a weekly schedule and overall syllabus for fall and spring, as well as activities for each lesson and answer keys. Students will be able to access downloadable character practice worksheets along with interactive pronunciation, vocabulary and character practice exercises. All the audio material necessary for the course is also available online and conveniently linked on screen to the relevant exercises for ease-of-use. For more information about the course and to access these additional resources, please visit the companion website at http://cw.routledge.com/textbooks/9780415472500/ For bundle discounts please visit: http://www.routledge.com/books/details/9780415533089/

Inorganic Syntheses, Volume 32

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Publisher : John Wiley & Sons
ISBN 13 : 0470132981
Total Pages : 360 pages
Book Rating : 4.4/5 (71 download)

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Book Synopsis Inorganic Syntheses, Volume 32 by :

Download or read book Inorganic Syntheses, Volume 32 written by and published by John Wiley & Sons. This book was released on 2009-09-22 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Inorganic Synthesis Series provides all users of inorganic substances with detailed and foolproof procedures for the preparation of important and timely compounds. This new volume includes information on water-solubilizing ligands for organometallics, labile ligand complexes, and the syntheses of cluster compounds and hydrides.

Bioinorganic Photochemistry

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Publisher : John Wiley & Sons
ISBN 13 : 9781405193276
Total Pages : 398 pages
Book Rating : 4.1/5 (932 download)

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Book Synopsis Bioinorganic Photochemistry by : Grazyna Stochel

Download or read book Bioinorganic Photochemistry written by Grazyna Stochel and published by John Wiley & Sons. This book was released on 2009-06-10 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioinorganic photochemistry is a rapidly evolving field integrating inorganic photochemistry with biological, medical and environmental sciences. The interactions of light with inorganic species in natural systems, and the applications in artificial systems of medical or environmental importance, form the basis of this challenging inter-disciplinary research area. Bioinorganic Photochemistry provides a comprehensive overview of the concepts and reactions fundamental to the field, illustrating important applications in biological, medical and environmental sciences. Topics covered include: Cosmic and environmental photochemistry Photochemistry of biologically relevant nanoassemblies Molecular aspects of photosynthesis Photoinduced electron transfer in biosystems Modern therapeutic strategies in photomedicine The book concludes with an outlook for the future of environmental protection, discussing emerging techniques in the field of pollution abatement, and the potential for bioinorganic photochemistry as a pathway to developing cheap, environmentally friendly sources of energy. Written as an authoritative guide for researchers involved in the development of bioinorganic photochemical processes, Bioinorganic Photochemistry is also accessible to scientists new to the field, and will be a key reference source for advanced courses in inorganic, and bioinorganic chemistry.

March's Advanced Organic Chemistry

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Publisher : John Wiley & Sons
ISBN 13 : 0470084944
Total Pages : 2379 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis March's Advanced Organic Chemistry by : Michael B. Smith

Download or read book March's Advanced Organic Chemistry written by Michael B. Smith and published by John Wiley & Sons. This book was released on 2007-01-29 with total page 2379 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Sixth Edition of a classic in organic chemistry continues its tradition of excellence Now in its sixth edition, March's Advanced Organic Chemistry remains the gold standard in organic chemistry. Throughout its six editions, students and chemists from around the world have relied on it as an essential resource for planning and executing synthetic reactions. The Sixth Edition brings the text completely current with the most recent organic reactions. In addition, the references have been updated to enable readers to find the latest primary and review literature with ease. New features include: More than 25,000 references to the literature to facilitate further research Revised mechanisms, where required, that explain concepts in clear modern terms Revisions and updates to each chapter to bring them all fully up to date with the latest reactions and discoveries A revised Appendix B to facilitate correlating chapter sections with synthetic transformations

Side Reactions in Organic Synthesis

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Publisher : John Wiley & Sons
ISBN 13 : 3527604987
Total Pages : 389 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Side Reactions in Organic Synthesis by : Florencio Zaragoza Dörwald

Download or read book Side Reactions in Organic Synthesis written by Florencio Zaragoza Dörwald and published by John Wiley & Sons. This book was released on 2006-03-06 with total page 389 pages. Available in PDF, EPUB and Kindle. Book excerpt: Most syntheses in the chemical research laboratory fail and usually require several attempts before proceeding satisfactorily. Failed syntheses are not only discouraging and frustrating, but also cost a lot of time and money. Many failures may, however, be avoided by understanding the structure-reactivity relationship of organic compounds. This textbook highlights the competing processes and limitations of the most important reactions used in organic synthesis. By allowing chemists to quickly recognize potential problems this book will help to improve their efficiency and success-rate. A must for every graduate student but also for every chemist in industry and academia. Contents: 1 Organic Synthesis: General Remarks 2 Stereoelectronic Effects and Reactivity 3 The Stability of Organic Compounds 4 Aliphatic Nucleophilic Substitutions: Problematic Electrophiles 5 The Alkylation of Carbanions 6 The Alkylation of Heteroatoms 7 The Acylation of Heteroatoms 8 Palladium-Catalyzed C-C Bond Formation 9 Cyclizations 10 Monofunctionalization of Symmetric Difunctional Substrates

Modern Coordination Chemistry

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Publisher : Royal Society of Chemistry
ISBN 13 : 1847551483
Total Pages : 416 pages
Book Rating : 4.8/5 (475 download)

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Book Synopsis Modern Coordination Chemistry by : Jeff Leigh

Download or read book Modern Coordination Chemistry written by Jeff Leigh and published by Royal Society of Chemistry. This book was released on 2007-10-31 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: Coordination chemistry, as we know it today, has been shaped by major figures from the past, one of whom was Joseph Chatt. Beginning with a description of Chatt's career presented by co-workers, contemporaries and students, this fascinating book then goes on to show how many of today's leading practitioners in the field, working in such diverse areas as phosphines, hydrogen complexes, transition metal complexes and nitrogen fixation, have been influenced by Chatt. The reader is then brought right up-to-date with the inclusion of some of the latest research on these topics, all of which serves to underline Chatt's continuing legacy. Intended as a permanent record of Chatt's life, work and influence, this book will be of interest to lecturers, graduate students, researchers and science historians.

Luminescent and Photoactive Transition Metal Complexes as Biomolecular Probes and Cellular Reagents

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Publisher :
ISBN 13 : 9783662467190
Total Pages : pages
Book Rating : 4.4/5 (671 download)

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Book Synopsis Luminescent and Photoactive Transition Metal Complexes as Biomolecular Probes and Cellular Reagents by : Kenneth Kam-Wing Lo

Download or read book Luminescent and Photoactive Transition Metal Complexes as Biomolecular Probes and Cellular Reagents written by Kenneth Kam-Wing Lo and published by . This book was released on 2015 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The series Structure and Bonding publishes critical reviews on topics of research concerned with chemical structure and bonding. The scope of the series spans the entire Periodic Table and addresses structure and bonding issues associated with all of the elements. It also focuses attention on new and developing areas of modern structural and theoretical chemistry such as nanostructures, molecular electronics, designed molecular solids, surfaces, metal clusters and supramolecular structures. Physical and spectroscopic techniques used to determine, examine and model structures fall within the purview of Structure and Bonding to the extent that the focus is on the scientific results obtained and not on specialist information concerning the techniques themselves. Issues associated with the development of bonding models and generalizations that illuminate the reactivity pathways and rates of chemical processes are also relevant. The individual volumes in the series are thematic. The goal of each volume is to give the reader, whether at a university or in industry, a comprehensive overview of an area where new insights are emerging that are of interest to a larger scientific audience. Thus each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years should be presented using selected examples to illustrate the principles discussed. A description of the physical basis of the experimental techniques that have been used to provide the primary data may also be appropriate, if it has not been covered in detail elsewhere. The coverage need not be exhaustive in data, but should rather be conceptual, concentrating on the new principles being developed that will allow the reader, who is not a specialist in the area covered, to understand the data presented. Discussion of possible future research directions in the area is welcomed. Review articles for the individual volumes are invited by the volume editors. Readership: research scientists at universities or in industry, graduate students Special offer For all customers who have a standing order to the print version of Structure and Bonding, we offer free access to the electronic volumes of the Series published in the current year via SpringerLink.

Aromatic Thiols and Their Derivatives

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Publisher : Springer Nature
ISBN 13 : 3030696219
Total Pages : 388 pages
Book Rating : 4.0/5 (36 download)

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Book Synopsis Aromatic Thiols and Their Derivatives by : Ismayil A. Aliyev

Download or read book Aromatic Thiols and Their Derivatives written by Ismayil A. Aliyev and published by Springer Nature. This book was released on 2021-05-24 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is devoted to the synthetic and physical chemistry of aromatic thiols and their closest derivatives, sulfides, sulfoxides, sulfones, including those substituted by various functional groups such as acyl and thioacyl, alkoxide, ester, hydroxyl and halogens. In some cases, for comparison, selenium and oxygen analogues are also detailed. The main focus of the book is on synthetic methods, both traditional and new, based on the use of transition metals as catalysts, as well as the reactivity of the compounds obtained. Its addition to the influence of conformational and electronic factors on spectral (NMR, IR, UV, NQR) and electrochemical characteristics of the compounds is presented. Finally, the book describes the application of aromatic thiols and their derivatives as drug precursors, high-tech materials, building blocks for organic synthesis, analytical reagents and additives for oils and fuels. It is a useful handbook for all those interested in organosulfur chemistry.

The Chemistry of Mercury

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Publisher : Springer
ISBN 13 : 1349024899
Total Pages : 290 pages
Book Rating : 4.3/5 (49 download)

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Book Synopsis The Chemistry of Mercury by : Charles Andrew McAuliffe

Download or read book The Chemistry of Mercury written by Charles Andrew McAuliffe and published by Springer. This book was released on 2016-03-21 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cisplatin

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Publisher : John Wiley & Sons
ISBN 13 : 9783906390208
Total Pages : 630 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis Cisplatin by : Bernhard Lippert

Download or read book Cisplatin written by Bernhard Lippert and published by John Wiley & Sons. This book was released on 1999 with total page 630 pages. Available in PDF, EPUB and Kindle. Book excerpt: 30 years after its discovery as an antitumor agent, cisplatin represents today one of the most successful drugs in chemotherapy. This book is intended to reminisce this event, to take inventory, and to point out new lines of development in this field. Divided in 6 sections and 22 chapters, the book provides an up-to-date account on topics such as - the chemistry and biochemistry of cisplatin, - the clinical status of Pt anticancer drugs, - the impact of cisplatin on inorganic and coordination chemistry, - new developments in drug design, testing and delivery. It also includes a chapter describing the historical development of the discovery of cisplatin. The ultimate question - How does cisplatin kill a cell? - is yet to be answered, but there are now new links suggesting how Pt binding to DNA may trigger a cascade of cellular reactions that eventually result in apoptosis. p53 and a series of damage recognition proteins of the HMG-domain family appear to be involved. The book addresses the problem of mutagenicity of Pt drugs and raises the question of the possible relevance of the minor DNA adducts, e.g. of interstrand cross-links, and the possible use of trans-(NH3)2Pt(II)-modified oligonucleotides in antisense and antigene strategies. Our present understanding of reactions of cisplatin with DNA is based upon numerous model studies (from isolated model nucleobases to short DNA fragments) and application of a large body of spectroscopic and other physico-chemical techniques. Thanks to these efforts there is presently no other metal ion whose reactions with nucleic acids are better understood than Pt. In a series of chapters, basic studies on the interactions of Pt electrophiles with nucleobases, oligonucleotides, DNA, amino acids, peptides and proteins are reported, which use, among others, sophisticated NMR techniques or X-ray crystallography, to get remarkable understanding of details on such reactions. Reactivity of cisplatin, once bound to DNA and formerly believed to be inert enough to stay, is an emerging phenomenon. It has (not yet) widely been studied but is potentially extremely important. Medicinal bioinorganic chemistry - the role of metal compounds in medicine - has received an enormous boost from cisplatin, and so has bioinorganic chemistry as a whole. There is hardly a better example than cisplatin to demonstrate what bioinorganic chemistry is all about: The marriage between classic inorganic (coordination) chemistry and the other life sciences - medicine, pharmacy, biology, biochemistry. Cisplatin has left its mark also on areas that are generally considered largely inorganic. The subject of mixed-valance Pt compounds is an example: From the sleeping beauty it made its way to the headlines of scientific journals, thanks to a class of novel Pt antitumor agents, the so-called "platinum pyrimidine blues". In the aftermath diplatinum (III) compounds were recognized and studies in large numbers, and now an organometalic chemistry of these diplatinum (III) species is beginning to emerge. The final section of the book is concerned with new developments such as novel di- and trinuclear Pt(II) drugs with DNA binding properties different from those of cisplatin, with orally active Pt(IV) drugs which are presently in clinical studies, and with attempts to modify combinatorial chemistry in such a way that it may become applicable to fast screening of Pt antitumor drugs. The potential of including computational methods in solving questions of Pt-DNA interactions is critically dealt with in the concluding chapter.

Superbases for Organic Synthesis

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Publisher : John Wiley & Sons
ISBN 13 : 9780470740866
Total Pages : 336 pages
Book Rating : 4.7/5 (48 download)

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Book Synopsis Superbases for Organic Synthesis by : Tsutomu Ishikawa

Download or read book Superbases for Organic Synthesis written by Tsutomu Ishikawa and published by John Wiley & Sons. This book was released on 2009-01-26 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Guanidines, amidines and phosphazenes have been attracting attention in organic synthesis due to their potential functionality resulting from their extremely strong basicity. They are also promising catalysts because of their potential for easy molecular modification, possible recyclability, and reduced or zero toxicity. Importantly, these molecules can be derived as natural products – valuable as scientists move towards “sustainable chemistry”, where reagents and catalysts are derived from biomaterial sources. Superbases for Organic Synthesis is an essential guide to these important molecules for preparative organic synthesis. Topics covered include the following aspects: an introduction to organosuperbases physicochemical properties of organic superbases amidines and guanidines in organic synthesis phosphazene: preparation, reaction and catalytic role polymer-supported organosuperbases application of organosuperbases to total synthesis related organocatalysts: proton sponges and urea derivatives amidines and guanidines in natural products and medicines Superbases for Organic Synthesis is a comprehensive, authoritative and up-to-date guide to these important reagents for organic chemists, drug discovery researchers and those interested in the chemistry of natural products.

Sulfur Chemistry

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Publisher : Springer Nature
ISBN 13 : 3030255980
Total Pages : 477 pages
Book Rating : 4.0/5 (32 download)

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Book Synopsis Sulfur Chemistry by : Xuefeng Jiang

Download or read book Sulfur Chemistry written by Xuefeng Jiang and published by Springer Nature. This book was released on 2019-08-28 with total page 477 pages. Available in PDF, EPUB and Kindle. Book excerpt: The series Topics in Current Chemistry Collections presents critical reviews from the journal Topics in Current Chemistry organized in topical volumes. The scope of coverage is all areas of chemical science including the interfaces with related disciplines such as biology, medicine and materials science. The goal of each thematic volume is to give the non-specialist reader, whether in academia or industry, a comprehensive insight into an area where new research is emerging which is of interest to a larger scientific audience. Each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years are presented using selected examples to illustrate the principles discussed. The coverage is not intended to be an exhaustive summary of the field or include large quantities of data, but should rather be conceptual, concentrating on the methodological thinking that will allow the non-specialist reader to understand the information presented. Contributions also offer an outlook on potential future developments in the field.

Metal Ions in Biological Systems

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Publisher : CRC Press
ISBN 13 : 9780824799847
Total Pages : 826 pages
Book Rating : 4.7/5 (998 download)

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Book Synopsis Metal Ions in Biological Systems by : Astrid Sigel

Download or read book Metal Ions in Biological Systems written by Astrid Sigel and published by CRC Press. This book was released on 1998-01-09 with total page 826 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Volume 35 covers the biological cycling of iron in oceans; the transport of iron in microorganisms, fungi, and plants; the roles and properties of siderophores; the regulation of iron transport and uptake in animals, plants, and microorganisms, and more. "