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Rare Earth Doped Nanomaterials As Potential Contrast Agents
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Book Synopsis Rare Earth Doped Nanomaterials As Potential Contrast Agents by : Gautom K. Das
Download or read book Rare Earth Doped Nanomaterials As Potential Contrast Agents written by Gautom K. Das and published by LAP Lambert Academic Publishing. This book was released on 2010-07 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: The work presented in this book focuses on the fabrication of rare earth (RE) doped nanomaterials as potential contrast agents for optical and magnetic resonance imaging.Owing to the sharp and intense emission obtained over the range of visible to the nearinfrared regions in a wide variety of hosts, RE-doped nanomaterials have attracted strong interests as contrast agents in bioimaging applications. This work has successfully demonstrated the fabrication of single-phase fluorescent, and bifunctional magnetic-fluorescent RE-doped nanomaterials as well as investigated their potential cytotoxic effects, and in vitro MRI image contrast.
Book Synopsis Lanthanide-Doped Luminescent Nanomaterials by : Xueyuan Chen
Download or read book Lanthanide-Doped Luminescent Nanomaterials written by Xueyuan Chen and published by Springer Science & Business Media. This book was released on 2013-11-04 with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lanthanide-Doped Luminescent Nanomaterials reviews the latest advances in the development of lanthanide-doped luminescent inorganic nanoparticles for potential bioapplications. This book covers the chemical and physical fundamentals of these nanoparticles, such as the controlled synthesis methodology, surface modification chemistry, optical physics, and their promising applications in diverse bioassays, with an emphasis on heterogeneous and homogeneous in-vitro biodetection of tumor biomarkers. This book is intended for those readers who are interested in systematically understanding the materials design strategy, optical behavior of lanthanide ions, and practical bioapplications of lanthanide nanoparticles. It primarily focuses on the interdisciplinary frontiers in chemistry, physics and biological aspects of luminescent nanomaterials. All chapters were written by scientists active in this field and for a broad audience, providing both beginners and advanced researchers with comprehensive information on the subject. Xueyuan Chen is a Professor at Fujian Institute of Research on the Structure of Matter (FJIRSM), Chinese Academy of Sciences. Yongsheng Liu is a Research Associate Professor at FJIRSM, Chinese Academy of Sciences. Datao Tu is a Research Assistant Professor at FJIRSM, Chinese Academy of Sciences.
Book Synopsis Rare Earths Based Nir Luminomagnetic Nanoparticles and Their Multimodal Applications in Biomedical Imaging by : L. Christopher Mimun
Download or read book Rare Earths Based Nir Luminomagnetic Nanoparticles and Their Multimodal Applications in Biomedical Imaging written by L. Christopher Mimun and published by . This book was released on 2015 with total page 137 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medical imaging is one of the most important techniques in the medical field for diagnostics and analysis of biological tissues. The most common imaging modalities are X-ray, Magnetic Resonance Imaging (MRI), and optical imaging. In each of these imaging techniques, several contrast agents are used to improve the image resolution. There are several contrast agents available that are specific for a particular application and only include one functionality. In addition, most of the contrast agents available today have several limitations such as low image resolution, low thermal stability, toxicity, cost of production etc. The development of an ideal contrast agent with multiple functionalities that overcome most of these limitations is a challenging topic in the medical industry. Furthermore, by adding multiple functionalities into a single contrast agent the benefits would provide a decrease in cost and time by imaging multiple modalities simultaneously. Though there are various attempts in this area by several researchers around the world, the idea of developing a core-shell free multifunctional contrast agent with near infrared (NIR) imaging features and magnetic properties is novel. This doctoral dissertation is focused on the investigation of rare earth doped, NIR active, luminomagnetic nanocrystals (NCs) that have the potential to be effective contrast with multiple modalities. The main content of the thesis is about the development, characterization, and implementation of Nd 3+ doped YF3, GdF3, and Na(Lu0.5Gd 0.5)F4. The “as prepared” and surface functionalized NCs are characterized for their phase, morphology, and detailed optical characteristics such as absorption, emission and quantum yield. Magnetic properties are studied by magnetization experiments. In order to show the proof of concept as a multifunctional imaging agent various imaging experiments such as confocal intracellular imaging, NIR optical imaging, X-ray imaging and magnetic resonance imaging experiments were conducted and their performance was validated by the outcome of these experiments.
Book Synopsis Synthesis of Rare-earth Containing Nanoparticles by : Paula S. Rahman
Download or read book Synthesis of Rare-earth Containing Nanoparticles written by Paula S. Rahman and published by . This book was released on 2010 with total page 470 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rare earth based nanoparticles have luminescent and paramagnetic properties which have potential use for applications in medical imaging, display technologies and lasers. Some Ln 3+ ions luminesce in the visible range, for example Eu3+ emits in the red and Tb3+ in the green. Ln3+ optical emission is very narrow and is not affected by the local environment. This property has found use in emissive displays. Most Ln3+ ions are paramagnetic, again a property which is expected to remain in most Ln3+-based compounds. Gd3+ in particular has found use as an MRI contrast agent as it has a high magnetic moment. -- In this work attempts were made to synthesise europium, terbium and dysprosium phosphide (REP) nanoparticles. An organometallic-based precursor route with coordinating solvents using tris(dimethylamino) phosphine as the phosphorous source was chosen as the synthetic route. Results indicated that the target nanoparticles were synthesised when using rare earth chloride as the metal precursors and TOPO as the coordinating ligand and solvent. The products from these reactions were most likely a mixture of products containing rare earth phosphide and phosphate nanoparticles and large particles and rare earth-TOPO complexes. The experiments reported for the phosphide syntheses are unique as there are no other reports of rare earth phosphide nanoparticles. TDMAP has also rarely been used as a phosphorous source for the synthesis of phosphide nanoparticles. -- Europium, terbium and gadolinium fluorides (REF3) were synthesised using several methods including routes using trifluoroacetate-based precursors. One finding was that the europium fluoride nanoparticles in particular displayed very long-range self-assembly. Europium-doped gadolinium fluoride nanoparticles were rendered water-soluble by PEGylation.
Download or read book Rare Earth written by Sooraj H. Nandyala and published by Materials Research Forum LLC. This book was released on 2024-06-05 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph represents a tribute to the late Prof. Karl Gschneidner, well known as “Mr. Rare Earth”, distinguished Professor of Materials Science and Engineering at the Iowa State University, a Senior Metallurgist at the Ames Laboratory, and the Chief Scientist of the Critical Materials Institute. Topics covered include Rare Earth Glass Spectroscopy, Treating Skin Diseases, Prospective Rare Earth Applications, Optical Information Storage, Diagnostic Imaging, Nanoparticles in Glasses, and ZnO Nanomaterials.
Book Synopsis Cerium Oxide Nanoparticles and Gadolinium Integration by : Peter Eriksson
Download or read book Cerium Oxide Nanoparticles and Gadolinium Integration written by Peter Eriksson and published by Linköping University Electronic Press. This book was released on 2019-08-29 with total page 48 pages. Available in PDF, EPUB and Kindle. Book excerpt: A challenging task, in the area of magnetic resonance imaging is to develop contrast enhancers with built-in antioxidant properties. Oxidative stress is considered to be involved in the onset and progression of several serious conditions such as Alzheimer’s and Parkinson’s disease, and the possibility to use cerium-contained nanoparticles to modulate such inflammatory response has gained a lot of interest lately. The rare earth element gadolinium is, due to its seven unpaired f-electrons and high symmetry of the electronic state, a powerful element for contrast enhancement in magnetic resonance imaging. Chelates based on gadolinium are the most commonly used contrast agents worldwide. When introducing external contrast agents there is always a risk that it may trigger inflammatory responses, why there is an urgent need for new, tailor-made contrast agents. Small sized cerium oxide nanoparticles have electronic structures that allows coexistence of oxidation states 3+ and 4+ of cerium, which correlates to applicable redox reactions in biomedicine. Such cerium oxide nanoparticles have recently shown to exhibit antioxidant properties both in vitro and in vivo, via the mechanisms involving enzyme mimicking activity. This PhD project is a comprehensive investigation of cerium oxide nanoparticles as scaffold materials for gadolinium integration. Gadolinium is well adopted into the crystal structure of cerium oxide, enabling the combination of diagnostic and therapeutic properties into a single nanoparticle. The main focus of this thesis project is to design cerium oxide nanoparticles with gadolinium integration. A stepwise approach was employed as follows: 1) synthesis with controlled integration of gadolinium, 2) material characterization by means of composition crystal structure, size, and size distribution and 3) surface modification for stabilization. The obtained nanoparticles exhibit remarkable antioxidant capability in vitro and in vivo. They deliver strongly enhanced contrast per gadolinium in magnetic resonance imaging, compared to commercially available contrast agents. A soft shell of dextran is introduced to encapsulate the cerium oxide nanoparticles with integrated gadolinium, which protects and stabilizes the hard core and to increases their biocompatibility. The dextran-coating is clearly shown to reduce formation of a protein corona and it improves the dispersibility of the nanoparticles in cell media. Functionalization strategies are currently being studied to endow these nanoparticles with specific tags for targeting purposes. This will enable guidance of the nanoparticles to a specific tissue, for high local magnetic resonance contrast complemented with properties for on-site reduced inflammation. In conclusion, our cerium oxide nanoparticles with integrated gadolinium, exhibit combined therapeutic and diagnostic, i.e. theragnostic capabilities. This type of nanomaterial is highly promising for applications in the field of biomedical imaging.
Book Synopsis Rare Earth Nanotechnology by : Timothy Tan Thatt Yang
Download or read book Rare Earth Nanotechnology written by Timothy Tan Thatt Yang and published by CRC Press. This book was released on 2012-06-20 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides in-depth aspects of nanotechnology of rare earth (RE) materials. It starts with a review on the physical and chemical properties of RE elements, followed by a discussion on various strategies in fabricating nanosized RE materials. It describes various techniques in derivatizing surface molecules onto nanosized RE materials. A considerable portion of the book is devoted to the review and discussion of the application of nanosized RE materials as contrast agents in in vitro and in vivo fluorescence imaging, MRI, and integrated modalities imaging. The book also discusses the application of RE nanomaterials in LEDs.
Book Synopsis Near Infrared-Emitting Nanoparticles for Biomedical Applications by : Antonio Benayas
Download or read book Near Infrared-Emitting Nanoparticles for Biomedical Applications written by Antonio Benayas and published by Springer Nature. This book was released on 2020-04-13 with total page 391 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book analyzes and evaluates the growing field of light-emitting nanoprobes as contrast agents for in vivo imaging and sensing. It is a comprehensive resource that critically analyzes the state of the art in an interdisciplinary manner, with a special focus on the shift of emission wavelengths into the near-infrared (NIR) spectral region (ranging from 0.7 to 2 microns), which has greatly contributed to the latest advances in biomedical imaging and sensing. This book discusses merits of different contrast agents at nanoscale, and how their unique chemical and structural properties lead to the emission and interaction of light within the NIR window. Both the NIR-emitting materials and various surface modification strategies governing their interactions with the biological system at the “nano” level are discussed. Furthermore, different experimental techniques and protocols for NIR-light-based in vivo imaging and sensing are addressed to shed light on further understanding of the advantages and limitations of each category of these nanoprobes. Assembles the state of the art heretofore appearing in scientific literature into a comprehensive, multi-perspective guidebook on near infrared-emitting nanomaterials in an assortment of biomedical applications; Explains the physical, chemical, and biological phenomena underlying near infrared-emitting nanomaterials for biomedical applications; Presents conceptual and experimental approaches surrounding a unique spectral range of light emission from nanosized contrast agents, while offering a clear explanation of basic and general phenomena regarding the interaction between light and biological tissues, such as absorption, scattering and autofluorescence.
Book Synopsis Advanced Rare Earth-Based Ceramic Nanomaterials by : Sahar Zinatloo-Ajabshir
Download or read book Advanced Rare Earth-Based Ceramic Nanomaterials written by Sahar Zinatloo-Ajabshir and published by Elsevier. This book was released on 2022-01-15 with total page 413 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advanced Rare Earth-Based Ceramic Nanomaterials focuses on recent advances related to preparation methods and applications of advanced rare earth-based ceramic nanomaterials. Different approaches for synthesizing rare earth-based ceramic nanomaterials are discussed, along with their advantages and disadvantages for applications in various fields. Sections cover rare earth-based ceramic nanomaterials like ceria and rare earth oxides (R2O3), rare earth vanadates, rare earth titanates, rare earth zirconates, rare earth stannates, rare earth-based tungstates, rare earth-based manganites, ferrites, cobaltites, nickelates, rare earth doped semiconductor nanomaterials, rare earth molybdates, rare earth-based nanocomposites, rare earth-based compounds for solar cells, and laser nanomaterials based on rare-earth compounds. Reviews the chemistry and processing of rare earth doped ceramic nanomaterials and their characteristics and applications Covers a broad range of materials, including ceria and rare earth oxides (R2O3), vanadates, titanates, zirconates, stannates, tungstates, manganites, ferrites, cobaltites, nickelates, rare earth doped semiconductor nanomaterials, rare earth molybdates, rare earth-based nanocomposites, rare earth-based compounds for solar cells, and laser nanomaterials based on rare-earth compounds Includes different approaches to synthesizing each family of rare earth-based ceramic nanomaterials, along with their advantages and disadvantages Provides green chemistry-based methods for the preparation of advanced rare earth-based ceramic nanomaterials
Book Synopsis Handbook on the Physics and Chemistry of Rare Earths by : Jean-Claude G. Bunzli
Download or read book Handbook on the Physics and Chemistry of Rare Earths written by Jean-Claude G. Bunzli and published by Elsevier. This book was released on 2022-11-04 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook on the Physics and Chemistry of Rare Earths: Including Actinides, Volume 62, the latest release in this continuous series that covers all aspects of rare earth science, including chemistry, life sciences, materials science and physics, presents interesting chapters on a variety of topics, with this release including sections on Lanthanide calixarene complexes and their applications, Recent developments in lanthanide-based single-molecule magnets, Rare earth permanent magnets, and the Importance of Ligand Design in Lanthanide Azamacrocyclic Complexes Relevant to Biomedical Applications. Presents up-to-date overviews and new developments in the field of rare earths, covering both their physics and chemistry Contains individual chapters that are comprehensive and broad, along with critical reviews Provides contributions from highly experienced, invited experts
Download or read book Hybrid Nanomaterials written by Weibo Cai and published by CRC Press. This book was released on 2017-05-25 with total page 451 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the last decade, an unprecedented expansion in the field of nanomedicine has resulted in the development of new nanomaterials for diagnosis and therapy of various diseases such as cancer. This book covers the design, synthesis and applications of various functionally-hybridized nanomaterials for biomedical applications. It includes strategies for design and synthesis of hybrid nanomaterials, surface engineering of various nanoparticle-based hybrid nanosystems for cancer imaging and therapy, toxicity aspects of nanomaterials and the challenges in translation research of hybrid nanomaterials.
Book Synopsis Metal Oxide Nanoparticles as Potential MRI Contrast Agents by : Naomi E. Jones
Download or read book Metal Oxide Nanoparticles as Potential MRI Contrast Agents written by Naomi E. Jones and published by . This book was released on 2015 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Magnetic Nanomaterials written by and published by John Wiley & Sons. This book was released on 2009-09-15 with total page 673 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book series Nanomaterials for the Life Sciences, provides an in-depth overview of all nanomaterial types and their uses in the life sciences. Each volume is dedicated to a specific material class and covers fundamentals, synthesis and characterization strategies, structure-property relationships and biomedical applications. The series brings nanomaterials to the Life Scientists and life science to the Materials Scientists so that synergies are seen and developed to the fullest. Written by international experts of various facets of this exciting field of research, the series is aimed at scientists of the following disciplines: biology, chemistry, materials science, physics, bioengineering, and medicine, together with cell biology, biomedical engineering, pharmaceutical chemistry, and toxicology, both in academia and fundamental research as well as in pharmaceutical companies. VOLUME 4 - Magnetic Nanomaterials This volume takes the reader on a tour showing how magnetic nanomaterials are used in the fields of diagnosis and therapy, as well as in tissue engineering and environmental applications.
Book Synopsis Metal Oxide-Carbon Hybrid Materials by : Muhammad Akram Chaudhry
Download or read book Metal Oxide-Carbon Hybrid Materials written by Muhammad Akram Chaudhry and published by Elsevier. This book was released on 2022-03-20 with total page 590 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metal Oxide–Carbon Hybrid Materials: Synthesis, Properties and Applications reviews the advances in the fabrication and application of metal oxide–carbon-based nanocomposite materials. Their unique properties make them ideal materials for gas-sensing, photonics, catalysis, opto-electronic, and energy-storage applications. In the first section, the historical background to the hybrid materials based on metal oxide–carbon and the hybridized metal oxide composites is provided. It also highlights several popular methods for the preparation of metal oxide–carbon composites through solid-state or solution-phase reactions, and extensively discusses the materials’ properties. Fossil fuels and renewable energy sources cannot meet the ever-increasing energy demands of an industrialized and technology-driven global society. Therefore, the role of metal oxide–carbon composites in energy generation, hydrogen production, and storage devices, such as rechargeable batteries and supercapacitors, is of extreme importance. These problems are discussed in in the second section of the book. Rapid industrialization has resulted in serious environmental issues which in turn have caused serious health problems that require the immediate attention of researchers. In the third section, the use of metal oxide–carbon composites in water purification, photodegradation of industrial contaminants, and biomedical applications that can help to clean the environment and provide better healthcare solutions is described. The final section is devoted to the consideration of problems associated with the development of sensors for various applications. Numerous studies performed in this area have shown that the use of composites can significantly improve the operating parameters of such devices. Metal Oxide–Carbon Hybrid Materials: Synthesis, Properties and Applications presents a comprehensive review of the science related to metal oxide–carbon composites and how researchers are utilizing these materials to provide solutions to a large array of problems. Reviews the fundamental properties and fabrication methods of metal-oxide–carbon composites Discusses applications in energy, including energy generation, hydrogen production and storage, rechargeable batteries, and supercapacitors Includes current and emerging applications in environmental remediation and sensing
Book Synopsis Handbook on the Physics and Chemistry of Rare Earths by :
Download or read book Handbook on the Physics and Chemistry of Rare Earths written by and published by Elsevier. This book was released on 2016-10-31 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook on the Physics and Chemistry of Rare Earths: Including Actinides is a continuous series of books covering all aspects of rare earth science, including chemistry, life sciences, materials science, and physics. The book's main emphasis is on rare earth elements [Sc, Y, and the lanthanides (La through Lu], but whenever relevant, information is also included on the closely related actinide elements. Individual chapters are comprehensive, broad, up-to-date, critical reviews written by highly experienced, invited experts. The series, which was started in 1978 by Professor Karl A. Gschneidner Jr., combines, and integrates, both the fundamentals and applications of these elements with two published volumes each year. Presents up-to-date overviews and new developments in the field of rare earths, covering both their physics and chemistry Contains Individual chapters that are comprehensive and broad, with critical reviews Provides contributions from highly experienced, invited experts
Book Synopsis Smart Nanomaterials in Biomedical Applications by : Jin-Chul Kim
Download or read book Smart Nanomaterials in Biomedical Applications written by Jin-Chul Kim and published by Springer Nature. This book was released on 2022-01-19 with total page 603 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the start of 2020, the wrath of pandemic challenged the scientific community to develop more advanced drug delivery approaches for biomedical applications, endowing conventional drugs with additional therapeutic benefits and minimum side effects. Although significant advancements have been done in the field of drug delivery, there is a need to focus towards strategizing novel and improved drug delivery systems that should be convenient and cost-effective to the patients, and simultaneously they should also provide financial benefits to pharmaceutical companies. Controlled drug delivery technology offers ample opportunities and scope for improvising the therapeutic efficacy of drugs via optimizing the drug release rate and time. For this endeavour, smart nanomaterials have served as remarkable candidates for biomedical applications, owing to their ground-breaking properties and design. The development of such nanomaterials requires a broad knowledge related to their physio-chemical properties, molecular structure, mechanisms by which the nanomaterials interact with the cells, and methods by which drugs are released at the site of action. This knowledge must also be allied with the knowledge of signaling crosstalk mechanisms that are modulated by the nanomaterial-drugs composite. It can be anticipated that these emerging drug delivery technologies can facilitate the world to successfully encounter such pandemic outbursts in the future in a cost-effective and time-effective manner. The chapters in this book deal with the advanced technologies and approaches that can benefit advanced students, researchers, and industry experts in developing smart and intelligent nanomaterials for future biomedical applications, and development, manufacturing, and commercialization for controlled and targeted drug delivery.
Book Synopsis Molecular Imaging by : Brian D. Ross
Download or read book Molecular Imaging written by Brian D. Ross and published by Academic Press. This book was released on 2021-08-03 with total page 1872 pages. Available in PDF, EPUB and Kindle. Book excerpt: The detection and measurement of the dynamic regulation and interactions of cells and proteins within the living cell are critical to the understanding of cellular biology and pathophysiology. The multidisciplinary field of molecular imaging of living subjects continues to expand with dramatic advances in chemistry, molecular biology, therapeutics, engineering, medical physics and biomedical applications. Molecular Imaging: Principles and Practice, Volumes 1 and 2, Second Edition provides the first point of entry for physicians, scientists, and practitioners. This authoritative reference book provides a comprehensible overview along with in-depth presentation of molecular imaging concepts, technologies and applications making it the foremost source for both established and new investigators, collaborators, students and anyone interested in this exciting and important field. The most authoritative and comprehensive resource available in the molecular-imaging field, written by over 170 of the leading scientists from around the world who have evaluated and summarized the most important methods, principles, technologies and data Concepts illustrated with over 600 color figures and molecular-imaging examples Chapters/topics include, artificial intelligence and machine learning, use of online social media, virtual and augmented reality, optogenetics, FDA regulatory process of imaging agents and devices, emerging instrumentation, MR elastography, MR fingerprinting, operational radiation safety, multiscale imaging and uses in drug development This edition is packed with innovative science, including theranostics, light sheet fluorescence microscopy, (LSFM), mass spectrometry imaging, combining in vitro and in vivo diagnostics, Raman imaging, along with molecular and functional imaging applications Valuable applications of molecular imaging in pediatrics, oncology, autoimmune, cardiovascular and CNS diseases are also presented This resource helps integrate diverse multidisciplinary concepts associated with molecular imaging to provide readers with an improved understanding of current and future applications
