Radiosensitizers and Radioprotective Drugs

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Publisher :
ISBN 13 :
Total Pages : 764 pages
Book Rating : 4.3/5 (555 download)

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Book Synopsis Radiosensitizers and Radioprotective Drugs by : Rodolfo Paoletti

Download or read book Radiosensitizers and Radioprotective Drugs written by Rodolfo Paoletti and published by . This book was released on 1965 with total page 764 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Practical Radiation Oncology

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Publisher : Springer Nature
ISBN 13 : 9811500738
Total Pages : 282 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis Practical Radiation Oncology by : Supriya Mallick

Download or read book Practical Radiation Oncology written by Supriya Mallick and published by Springer Nature. This book was released on 2019-11-25 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses the most relevant aspects of radiation oncology in terms of technical integrity, dose parameters, machine and software specifications, as well as regulatory requirements. Radiation oncology is a unique field that combines physics and biology. As a result, it has not only a clinical aspect, but also a physics aspect and biology aspect, all three of which are inter-related and critical to optimal radiation treatment planning. In addition, radiation oncology involves a host of machines/software. One needs to have a firm command of these machines and their specifications to deliver comprehensive treatment. However, this information is not readily available, which poses serious challenges for students learning the planning aspect of radiation therapy. In response, this book compiles these relevant aspects in a single source. Radiation oncology is a dynamic field, and is continuously evolving. However, tracking down the latest findings is both difficult and time-consuming. Consequently, the book also comprehensively covers the most important trials. Offering an essential ready reference work, it represents a value asset for all radiation oncology practitioners, trainees and students.

Implications of Radiosensitizer and Radioprotector Factors in Refining the Dose-Volume Constraints and Radiobiological Models

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ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (139 download)

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Book Synopsis Implications of Radiosensitizer and Radioprotector Factors in Refining the Dose-Volume Constraints and Radiobiological Models by : Petru Teodor Dragos Iancu

Download or read book Implications of Radiosensitizer and Radioprotector Factors in Refining the Dose-Volume Constraints and Radiobiological Models written by Petru Teodor Dragos Iancu and published by . This book was released on 2018 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radiotherapy is a cornerstone of the modern treatment of many types of cancer, having both curative and palliative roles. It is estimated that more than half of cancer patients will need radiation therapy in the course of evolution. The goal of radiotherapy is to maximize tumor control, reducing adverse effects on normal tissues in close proximity at the same time. Improving the therapeutic ratio is the main goal of the efforts made to improve the technique and accuracy of the radiotherapy by using the targeting of the tumor volume with the help of the imaging guide and the dose conformation around the target volume. The use of the multi-leaf collimator (MLC) allowed a better coverage of the target volume in the irradiation field, thus reducing the unnecessary irradiation of healthy tissues. The use of radioprotective agents and radiosensitizers is another strategy to maximize the effect of radiotherapy. Recently, interest has focused on the design of irradiation protocols that exploit the differences in biology in terms of the response to irradiation between tumor cells and normal tissues.

Advanced Topics on Radiosensitizers of Hypoxic Cells

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Publisher : Springer Science & Business Media
ISBN 13 : 1475703996
Total Pages : 285 pages
Book Rating : 4.4/5 (757 download)

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Book Synopsis Advanced Topics on Radiosensitizers of Hypoxic Cells by : A. Breccia

Download or read book Advanced Topics on Radiosensitizers of Hypoxic Cells written by A. Breccia and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 285 pages. Available in PDF, EPUB and Kindle. Book excerpt: In July 1979, the Faculty of Pharmacy of the University of Bologna received a proposal from Professor Breccia to hold an International Conference on "Nitroimidazoles: Chemistry, Pharmacology and Clinical Application." Because of the great interest in these drugs in various fields, I was very pleased to accept the proposal and to give the conference the sponsorship of the University of Bologna. It was an added pleasure to accept the chairmanship of the meeting, together with Professors Sensi and Adams. At the same time, the Minister of Education approved a proposal which also came from the Faculty of Pharmacy, to offer an advanced course on the topic "Radiosensitizers of Hypoxic Cells This course was subsequently approved by a special Committee of the NATO Scientific Programme as an Advanced Study Institute. Since the subject matter of both the conference and the course are closely inter-related, it was logical to plan the conference as part of the overall course. Bringing together specialists from quite different and apparently unrelated fields of research, but all with an interest in the study and application of one single group of drugs, is a novel idea with intriguing possibilities. The volumes of the proceedings include contributions from experts with such diverse interests as synthetic chemistry, mechanism of drug action, parasitology, anaerobic bacteria and protozoa, pharmacology and toxicology, radiation sensitizers for use in radiotherapy, and the development of drugs for use in cancer in general.

The Molecular Targets and Therapeutic Uses of Curcumin in Health and Disease

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Publisher : Springer Science & Business Media
ISBN 13 : 0387464018
Total Pages : 502 pages
Book Rating : 4.3/5 (874 download)

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Book Synopsis The Molecular Targets and Therapeutic Uses of Curcumin in Health and Disease by : Bharat B. Aggarwal

Download or read book The Molecular Targets and Therapeutic Uses of Curcumin in Health and Disease written by Bharat B. Aggarwal and published by Springer Science & Business Media. This book was released on 2007-08-06 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt: The medicinal uses of Curcumin (also called turmeric) have been known and described for more than 5000 years. A large body of recent research suggests that curcumin is potentially useful in the treatment of inflammatory diseases, through modulation of numerous molecular targets. This is the first monograph to focus on the potential use of curcumin in the treatment of cancer, diabetes, cardiovascular diseases, arthritis, Alzheimer’s, psoriasis and more.

Modification of Radiosensitivity in Cancer Treatment

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Publisher :
ISBN 13 :
Total Pages : 576 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Modification of Radiosensitivity in Cancer Treatment by : Tsutomu Sugahara

Download or read book Modification of Radiosensitivity in Cancer Treatment written by Tsutomu Sugahara and published by . This book was released on 1984 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Advances in Radiation Therapy

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Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318063622
Total Pages : 146 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis Advances in Radiation Therapy by : M. Guckenberger

Download or read book Advances in Radiation Therapy written by M. Guckenberger and published by Karger Medical and Scientific Publishers. This book was released on 2018-04-12 with total page 146 pages. Available in PDF, EPUB and Kindle. Book excerpt: Developments in radiation oncology have been key to the tremendous progress made in the field in recent years. The combination of optimal systemic treatment and local therapy has resulted in continuing improved outcomes of cancer therapy. This progress forms the basis for current pre-clinical and clinical research which will strengthen the position of radiation oncology as an essential component of oncological care. This book summarizes recent advances in radiotherapy research and clinical patient care. Topics include radiobiology, radiotherapy technology, and particle therapy. Chapters cover a summary and analysis of recent developments in the search for biomarkers for precision radiotherapy, novel imaging possibilities and treatment planning, and advances in understanding the differences between photon and particle radiotherapy. Advances in Radiation Therapy is an invaluable source of information for scientists and clinicians working in the field of radiation oncology. It is also a relevant resource for those interested in the broad topic of radiotherapy in general.

Radiation Sensitizers, Their Use in the Clinical Management of Cancer

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Publisher :
ISBN 13 :
Total Pages : 552 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Radiation Sensitizers, Their Use in the Clinical Management of Cancer by : Luther W. Brady

Download or read book Radiation Sensitizers, Their Use in the Clinical Management of Cancer written by Luther W. Brady and published by . This book was released on 1980 with total page 552 pages. Available in PDF, EPUB and Kindle. Book excerpt:

1st International Symposium on Radiosensitizers and Radioprotective Drugs, Milan, 1964

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Publisher :
ISBN 13 :
Total Pages : 750 pages
Book Rating : 4.:/5 (65 download)

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Book Synopsis 1st International Symposium on Radiosensitizers and Radioprotective Drugs, Milan, 1964 by : Rodolfo Paoletti

Download or read book 1st International Symposium on Radiosensitizers and Radioprotective Drugs, Milan, 1964 written by Rodolfo Paoletti and published by . This book was released on 1964 with total page 750 pages. Available in PDF, EPUB and Kindle. Book excerpt:

International Symposium on Radiosensitizers and Radioprotective Drugs

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (251 download)

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Book Synopsis International Symposium on Radiosensitizers and Radioprotective Drugs by :

Download or read book International Symposium on Radiosensitizers and Radioprotective Drugs written by and published by . This book was released on 1965 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Textbook of Radiation Oncology

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Publisher :
ISBN 13 : 9780721600260
Total Pages : 0 pages
Book Rating : 4.6/5 (2 download)

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Book Synopsis Textbook of Radiation Oncology by : Steven A. Leibel

Download or read book Textbook of Radiation Oncology written by Steven A. Leibel and published by . This book was released on 2004 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thoroughly revised and updated, the 2nd Edition presents all of the latest advances in the field, including the most recent technologies and techniques. For each tumor site discussed, readers will find unparalleled coverage of multiple treatment plans, histology and biology of the tumor, its anatomic location and routes of spread, and utilization of specialized techniques. This convenient source also reviews all of the basic principles that underlie the selection and application of radiation as a treatment modality, including radiobiology, radiation physics, immobilization and simulation, high dose rate, intraoperative irradation, and more. Comprehensively reviews each topic, with a distinct clinical orientation throughout. Serves as a foundation for the basic principles that underlie the selection and application of radiation as a treatment modality, including radiobiology, radiation physics, immobilization and simulation, high dose rate, intraoperative irradation, and more. Guides readers through all stages of treatment application with step-by-step techniques for the assessment and implementation of radiotherapeutic options. Presents latest information on brachytherapy * 3-dimensional conformal treatment planning * sterotactic radiosurgery * and radiolabeled antibodies. Discusses the recent use of radiotherapy in the treatment of primary lymphoma, leukemia, multiple myeloma, and cancers of the prostate and central nervous system. Includes the latest AJCC staging system guidelines. Offers the latest advances in techniques, allowing you to deliver doses precisely to areas affected by malignancy and spare healthy tissue. Presents new chapters on the hottest topics including Three Dimensional Conformal Radiotherapy * Intensity Modulated Radiotherapy * Breathing Synchronized Radiotherapy * Plasma Cell Tumors: Multiple Myeloma and Solitary Plasmacytoma * Extracranial Stereotactic Radioablation * and [Imaging of the] Head and Neck * Thorax * Abdomen * and Pelvis.

First International Symposium on Radiosensitizers and Radioprotective Drugs, Milan 1964

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Author :
Publisher :
ISBN 13 :
Total Pages : 750 pages
Book Rating : 4.:/5 (688 download)

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Book Synopsis First International Symposium on Radiosensitizers and Radioprotective Drugs, Milan 1964 by : Radolfo Paoletti

Download or read book First International Symposium on Radiosensitizers and Radioprotective Drugs, Milan 1964 written by Radolfo Paoletti and published by . This book was released on 1965 with total page 750 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Multimodal Concepts for Integration of Cytotoxic Drugs

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Publisher : Springer Science & Business Media
ISBN 13 : 3540356622
Total Pages : 346 pages
Book Rating : 4.5/5 (43 download)

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Book Synopsis Multimodal Concepts for Integration of Cytotoxic Drugs by : Martin J. Brown

Download or read book Multimodal Concepts for Integration of Cytotoxic Drugs written by Martin J. Brown and published by Springer Science & Business Media. This book was released on 2006-08-06 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first part of this book summarizes the rationale and the preclinical data for combined treatment with ionizing radiation and pharmaceutical agents. Individual chapters focus on forms of combined treatment, with due consideration being given to a range of drugs and to emerging combinations with small molecules and antibodies. The second part comprises a series of disease-specific chapters in which the clinical results of combined modality treatment are presented.

Medicinal Chemistry of Anticancer Drugs

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Publisher : Elsevier
ISBN 13 : 0444626670
Total Pages : 767 pages
Book Rating : 4.4/5 (446 download)

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Book Synopsis Medicinal Chemistry of Anticancer Drugs by : Carmen Avendaño

Download or read book Medicinal Chemistry of Anticancer Drugs written by Carmen Avendaño and published by Elsevier. This book was released on 2015-06-11 with total page 767 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medicinal Chemistry of Anticancer Drugs, Second Edition, provides an updated treatment from the point of view of medicinal chemistry and drug design, focusing on the mechanism of action of antitumor drugs from the molecular level, and on the relationship between chemical structure and chemical and biochemical reactivity of antitumor agents. Antitumor chemotherapy is a very active field of research, and a huge amount of information on the topic is generated every year. Cytotoxic chemotherapy is gradually being supplemented by a new generation of drugs that recognize specific targets on the surface or inside cancer cells, and resistance to antitumor drugs continues to be investigated. While these therapies are in their infancy, they hold promise of more effective therapies with fewer side effects. Although many books are available that deal with clinical aspects of cancer chemotherapy, this book provides a sorely needed update from the point of view of medicinal chemistry and drug design. - Presents information in a clear and concise way using a large number of figures - Historical background provides insights on how the process of drug discovery in the anticancer field has evolved - Extensive references to primary literature

1. International Symposium on Radiosensitizers and Radioprotective Drugs, Milan 1964

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Author :
Publisher :
ISBN 13 :
Total Pages : 750 pages
Book Rating : 4.:/5 (25 download)

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Book Synopsis 1. International Symposium on Radiosensitizers and Radioprotective Drugs, Milan 1964 by : European Society for Biochemical Pharmacology

Download or read book 1. International Symposium on Radiosensitizers and Radioprotective Drugs, Milan 1964 written by European Society for Biochemical Pharmacology and published by . This book was released on 1965 with total page 750 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Radiation and the Immune System: Current Knowledge and Future Perspectives

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Publisher : Frontiers Media SA
ISBN 13 : 2889454746
Total Pages : 283 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis Radiation and the Immune System: Current Knowledge and Future Perspectives by : Katalin Lumniczky

Download or read book Radiation and the Immune System: Current Knowledge and Future Perspectives written by Katalin Lumniczky and published by Frontiers Media SA. This book was released on 2018-05-03 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: For long, high dose ionizing radiation was considered as a net immune suppressing agent, as shown, among others, by the exquisite radiosensitivity of the lymphoid system to radiation-induced cell killing. However, recent advances in radiobiology and immunology have made this picture more complex. For example, the recognition that radiation-induced bystander effects, share common mediators with various immunological signalling processes, suggests that they are at least partly immune mediated. Another milestone was the finding, in the field of onco-immunology, that local tumor irradiation can modulate the immunogenicity of tumor cells and the anti-tumor immune responsiveness both locally, in the tumor microenvironment, and at systemic level. These observations paved the way for studies exploring optimal combinations of radiotherapy and immunotherapy in order to achieve a synergistic effect to eradicate tumors. However, not all interactions between radiation and the immune system are beneficial, as it was recognized that many of radiation-induced late side effects are also of immune and inflammatory nature. Currently perhaps the most studied field of research in radiation biology is focused around the biological effects of low doses, where many of the observed pathophysiological endpoints are due to mechanisms other than direct radiation-induced cell killing and are immune-related. Finally, it must not be forgotten that the interactions between the ionizing radiations and the immune system are bi-directional, and activation of the immune system also influences the outcome of radiation exposure. This Research Topic brings together 23 articles and aims to give an overview of the complex and very often contradictory nature of the interactions between ionizing radiation and the immune system. Due to its increasing penetrance in the population both through medical diagnostic or environmental sources or during cosmic travel low dose ionizing radiation exposure is becoming a major epidemiological concern world-wide. Several of the articles within the Research Topic specifically address potential long-term health consequences and the underlying mechanisms of low dose radiation exposure. A major intention of the Editors was also to draw the attention of the non-radiobiological scientific community on the fact that ionizing radiation is by far more than purely an immune suppressing agent.

Radioprotectors

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Publisher : CRC Press
ISBN 13 : 9780849347566
Total Pages : 450 pages
Book Rating : 4.3/5 (475 download)

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Book Synopsis Radioprotectors by : Edward A. Bump

Download or read book Radioprotectors written by Edward A. Bump and published by CRC Press. This book was released on 1997-12-29 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is essential to minimize damage to normal tissues during radiation therapy and many strategies have been employed in finding the best methods for radioprotection. This book integrates chemical, biological, and clinical perspectives on these strategies and developments, providing a comprehensive treatise. It emphasizes new concepts in radioprotection, aiming to inspire further basic science and clinical progress in radioprotector research. Radioprotectors: Chemical, Biological, and Clinical Perspectives includes the following topics: Early research on radioprotectors WR-2721, an aminothiol prodrug, as a radioprotector New results with naturally occurring thiols Nitroxides as effective radioprotectors in vitro and in vivo Radioprotection observed with radical scavengers or antioxidants Bone marrow radioprotection with cytokines and biological modifiers Multiple mechanisms of altering radiation response by eicosanoids Vascular response to radiation and the importance of vascular damage to normal tissue Modifiers of radiation-induced apoptosis Survey of clinical trials with radioprotectors Radiation biologists and oncologists, cancer researchers, and toxicologists will benefit from the findings discussed and strategies for future research.