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Radiobiology And Radiation Hormesis
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Book Synopsis Radiobiology and Radiation Hormesis by : Charles L. Sanders
Download or read book Radiobiology and Radiation Hormesis written by Charles L. Sanders and published by Springer. This book was released on 2017-08-08 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents new information on radiobiology that more clearly refutes the linear no-threshold (LNT) assumption and supports radiation hormesis. Fresh light is cast on the mechanisms of radiation hormesis and the potential benefits of low-dose ionizing radiation in preventing and treating a wide variety of inflammatory and proliferative diseases. It is proposed that these effects may derive from cellular communication via electromagnetic waves directed by DNA, with each cell acting as a quantum computer. Readers will also find close analysis of the negative impacts of radiophobia on many aspects of modern life, including attitudes to imaging technologies, licensing of nuclear power reactors, and preparedness for survival of nuclear war. The book will be of interest to researchers and scientists in radiobiology, radiation protection, health physics, medical physics, and radiology. Specifically, it will provide medical physicians, radiation oncologists, radiation epidemiologists, gerontologists, cell biologists, toxicologists, and nuclear engineers with a wide range of interesting facts and enlightening novel perspectives.
Book Synopsis Radiation Hormesis by : T. D. Luckey
Download or read book Radiation Hormesis written by T. D. Luckey and published by CRC Press. This book was released on 2020-10-28 with total page 317 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radiation Hormesis presents the only critical review of the effects of whole-body exposure to low doses of ionizing radiation in animals. This is a "must read" book for radiobiologists, health-conscious individuals, and serious environmentalists. Topics discussed include our radiation environment, radiation hormesis in cancer mortality, growth and development, reproduction and mutation, immunity, and cancer. Data is presented that indicates that low doses of ionizing radiation may actually be beneficial to human health. This information could invalidate the "zero thesis" and linear models used by most regulatory agencies. The implications regarding eliminating linear models and accepting radiation hormesis are also discussed.
Book Synopsis Radiation Hormesis and the Linear-No-Threshold Assumption by : Charles L. Sanders
Download or read book Radiation Hormesis and the Linear-No-Threshold Assumption written by Charles L. Sanders and published by Springer Science & Business Media. This book was released on 2009-11-07 with total page 221 pages. Available in PDF, EPUB and Kindle. Book excerpt: Current radiation protection standards are based upon the application of the linear no-threshold (LNT) assumption, which considers that even very low doses of ionizing radiation can cause cancer. The radiation hormesis hypothesis, by contrast, proposes that low-dose ionizing radiation is beneficial. In this book, the author examines all facets of radiation hormesis in detail, including the history of the concept and mechanisms, and presents comprehensive, up-to-date reviews for major cancer types. It is explained how low-dose radiation can in fact decrease all-cause and all-cancer mortality and help to control metastatic cancer. Attention is also drawn to biases in epidemiological research when using the LNT assumption. The author shows how proponents of the LNT assumption consistently reject, manipulate, and deliberately ignore an overwhelming abundance of published data and falsely claim that no reliable data are available at doses of less than 100 mSv.
Book Synopsis Hormesis With Ionizing Radiation by : T. D. Luckey
Download or read book Hormesis With Ionizing Radiation written by T. D. Luckey and published by CRC Press. This book was released on 2019-06-04 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: First published in 1980: The purpose of this Monograph, Hormesis With Ionizing Radiation, are to crystalize scattered information into an accepted subject of science and to awaken our society to new potential uses of ionizing radiation.
Download or read book Cellular Radiobiology written by T. Alper and published by Cambridge University Press. This book was released on 1979-08-16 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Radiation and Health by : Thormod Henriksen
Download or read book Radiation and Health written by Thormod Henriksen and published by CRC Press. This book was released on 2002-09-05 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radiation and the effects of radioactivity have been known for more than 100 years. International research spanning this period has yielded a great deal of information about radiation and its biological effects and this activity has resulted in the discovery of many applications in medicine and industry including cancer therapy, medical diagnostics
Author :Committee to Assess Health Risks from Exposure to Low Levels of Ionizing Radiation Publisher :National Academies Press ISBN 13 :0309133343 Total Pages :422 pages Book Rating :4.3/5 (91 download)
Book Synopsis Health Risks from Exposure to Low Levels of Ionizing Radiation by : Committee to Assess Health Risks from Exposure to Low Levels of Ionizing Radiation
Download or read book Health Risks from Exposure to Low Levels of Ionizing Radiation written by Committee to Assess Health Risks from Exposure to Low Levels of Ionizing Radiation and published by National Academies Press. This book was released on 2006-03-23 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the seventh in a series of titles from the National Research Council that addresses the effects of exposure to low dose LET (Linear Energy Transfer) ionizing radiation and human health. Updating information previously presented in the 1990 publication, Health Effects of Exposure to Low Levels of Ionizing Radiation: BEIR V, this book draws upon new data in both epidemiologic and experimental research. Ionizing radiation arises from both natural and man-made sources and at very high doses can produce damaging effects in human tissue that can be evident within days after exposure. However, it is the low-dose exposures that are the focus of this book. So-called “late” effects, such as cancer, are produced many years after the initial exposure. This book is among the first of its kind to include detailed risk estimates for cancer incidence in addition to cancer mortality. BEIR VII offers a full review of the available biological, biophysical, and epidemiological literature since the last BEIR report on the subject and develops the most up-to-date and comprehensive risk estimates for cancer and other health effects from exposure to low-level ionizing radiation.
Book Synopsis Radiation Biophysics (ionizing Radiations) by : I︠U︡riĭ Borisovich Kudri︠a︡shov
Download or read book Radiation Biophysics (ionizing Radiations) written by I︠U︡riĭ Borisovich Kudri︠a︡shov and published by Nova Publishers. This book was released on 2008 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book is concerned with features analysis of radiation damage to living matter at different levels of its organisation, beginning from the molecular level. The general theory of the mechanisms of biological action of radiation based on four logically connected principles of radiation biology is presented for the first time. The book contains abundant material on primary and secondary processes of the response of living systems to radiation, the mechanisms of direct and indirect action of radiation through radiolysis of water and lipids; a detailed consideration of the theory of targets (DNA and biological membranes) and the problems of high- and low-dose irradiation in the context of present-day. The systemic response of the cell to irradiation (oxidative stress, endogenous background radioresistance, damage and repair of biological membranes and DNA, systemic protection against radiation) is approximated. Presentation of these important problems is preceded by an up-to-date evaluation of some aspects regarding dosimetry of ionising radiation.
Book Synopsis Biological Radiation Effects by : Jürgen Kiefer
Download or read book Biological Radiation Effects written by Jürgen Kiefer and published by Springer. This book was released on 1990-01-25 with total page 468 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book covers all aspects of biological radiation effects and provides the fundamental basis for understanding the necessity of radiation protection as well as applications in radiotherapy. The physical basis is dealt with in some detail, and the effects at the subcellular and the cellular level are thoroughly discussed, taking into account modern developments and techniques. The effects on the human organism are reviewed, both from the point of view of applications in medicine as well as with regard to radiation hazards (teratogenic, gonadal and carcinogenic effects). It can be used by graduate students as an introduction and as a source book for all who want to become acquainted with this important field. It is an extended version of the original German book containing updated information and new material.
Book Synopsis Practical Radiation Protection in Healthcare by : Colin J. Martin
Download or read book Practical Radiation Protection in Healthcare written by Colin J. Martin and published by Oxford University Press, USA. This book was released on 2015 with total page 551 pages. Available in PDF, EPUB and Kindle. Book excerpt: A practical guide for medical physicists and those whose work involves any aspect of hospital radiation protection. It provides guidance on methods that may be used to tackle the tasks that a physicist working in this area might encounter.
Book Synopsis The Pathophysiologic Basis of Nuclear Medicine by : Abdelhamid H. Elgazzar
Download or read book The Pathophysiologic Basis of Nuclear Medicine written by Abdelhamid H. Elgazzar and published by Springer. This book was released on 2014-09-01 with total page 763 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, now in its third edition, aims to promote a deeper understanding of the scientific and clinical basis of nuclear medicine and the new directions in medical imaging. The new edition has been revised and updated to reflect recent changes and to ensure that the contents are in line with likely future directions. The book starts by providing essential information on general pathophysiology, cell structure and cell biology as well as the mechanisms of radiopharmaceutical localization in different tissues and cells. The clinical applications of nuclear medicine are then presented in a series of chapters that cover every major organ system and relate the basic knowledge of anatomy, physiology and pathology to the clinical utilization of various scintigraphic modalities. The therapeutic applications of nuclear medicine are discussed in a separate chapter, and the final chapter is devoted to the biologic effects of ionizing radiations, including radiation from medical procedures.
Author :National Academies of Sciences, Engineering, and Medicine Publisher :National Academies Press ISBN 13 :030949771X Total Pages :143 pages Book Rating :4.3/5 (94 download)
Book Synopsis The Future of Low Dose Radiation Research in the United States by : National Academies of Sciences, Engineering, and Medicine
Download or read book The Future of Low Dose Radiation Research in the United States written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2020-01-13 with total page 143 pages. Available in PDF, EPUB and Kindle. Book excerpt: Exposures at low doses of radiation, generally taken to mean doses below 100 millisieverts, are of primary interest for setting standards for protecting individuals against the adverse effects of ionizing radiation. However, there are considerable uncertainties associated with current best estimates of risks and gaps in knowledge on critical scientific issues that relate to low dose radiation. The Nuclear and Radiation Studies Board of the National Academies hosted the symposium on The Future of Low Dose Radiation Research in the United States on May 8 and 9, 2019. The goal of the symposium was to provide an open forum for a national discussion on the need for a long-term strategy to guide a low dose radiation research program in the United States. The symposium featured presentations on low dose radiation programs around the world, panel discussions with representatives from governmental and nongovernmental organizations about the need for a low dose radiation research program, reviews of low dose radiation research in epidemiology and radiation biology including new directions, and lessons to be learned from setting up large research programs in non-radiation research fields. This publication summarizes the presentation and discussion of the symposium.
Book Synopsis Fundamentals of Radiation and Chemical Safety by : Ilya Obodovskiy
Download or read book Fundamentals of Radiation and Chemical Safety written by Ilya Obodovskiy and published by Elsevier. This book was released on 2015-02-04 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fundamentals of Radiation and Chemical Safety covers the effects and mechanisms involved in radiation and chemical exposure on humans. The mechanisms and effects of these damaging factors have many aspects in common, as do their research methodology and the methods used for data processing. In many cases of these types of exposures the same final effect can also be noted: Cancer. Low doses of radiation and small doses of chemical exposure are continuously active and they could influence the entire population. The analysis of these two main source hazards on the lives of the human population is covered here for the first time in a single volume determining and demonstrating their common basis. Fundamentals of Radiation and Chemical Safety includes the necessary knowledge from nuclear physics, chemistry and biology, as well the methods of processing the experimental results. This title focuses on the effects of low radiation dosage and chemical hormesis as well as the hazards associated with, and safety precautions in radiation and chemicals, rather than the more commonly noted safety issues high level emergencies and disasters of this type. Brings together, for the first time, the problems of radiation and chemical safety on a common biophysical basis. Relates hazards caused by ionizing radiation and chemicals and discusses the common effective mechanisms Outlines common methodology and data processing between radiation and regular chemical hazards Concerns primarily with low levels of radiation and chemical exposure
Book Synopsis Genetic Instability and Some Unusual Radiobiological Effects by : Ekaterina S. Evstratova
Download or read book Genetic Instability and Some Unusual Radiobiological Effects written by Ekaterina S. Evstratova and published by . This book was released on 2022-06-30 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic instability leads to the accumulation of many changes necessary to transform the stable genome of a normal cell into an unstable genome. Such a transformation can be the cause of radiation mutagenesis, carcinogenesis and aging - the main long-term effects of ionizing radiation, UV light, and other harmful environmental factors. A new quantitative assessment of the genetic instability was suggested, taking into account the delay in the formation of colonies by cells surviving after exposure to harmful agents. It was demonstrated that the genetic instability of yeast cells is mainly determined by cell ploidy, but not by the sigmoid shape of the survival curve or the cell's ability of post-irradiation recovery. New experimental data confirm the participation of recovery processes in the manifestation of the relative biological effectiveness of densely ionizing radiation both for cell inactivation and for radiation-induced genetic instability. A number of universal patterns of synergic interactions are demonstrated, which did not depend on the used biological test and objects nor the interacting physical and chemical factors. Potential significance of synergy at low intensities of physical and chemical environmental factors is proved. Original data on the influence of cyclic heating and cooling on cell survival are obtained. It is concluded that osmotic homeostasis of cells, along with DNA, is an important target responsible for cell viability under the damaging action of various agents. Data on the favorable effect of the increased natural background of ionizing radiation are discussed. The manifestations of radiation hormesis were revealed for various radiation accidents, professional and medical exposure. The results obtained demonstrate that the action of high-energy ionizing radiation is accompanied by irradiation with UV light that occurs when charged particles move at a speed exceeding the speed of light in a given medium.
Download or read book Hormesis written by Mark P. Mattson and published by Springer Science & Business Media. This book was released on 2009-12-01 with total page 219 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hormesis is a poorly understood phenomenon affecting all forms of life on earth. This groundbreaking book summarizes and analyzes the various positives of hormesis in an attempt to reveal hormesis as a fundamental principle of biomedical sciences as a whole.
Book Synopsis Radiation and the Immune System: Current Knowledge and Future Perspectives by : Katalin Lumniczky
Download or read book Radiation and the Immune System: Current Knowledge and Future Perspectives written by Katalin Lumniczky and published by Frontiers Media SA. This book was released on 2018-05-03 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: For long, high dose ionizing radiation was considered as a net immune suppressing agent, as shown, among others, by the exquisite radiosensitivity of the lymphoid system to radiation-induced cell killing. However, recent advances in radiobiology and immunology have made this picture more complex. For example, the recognition that radiation-induced bystander effects, share common mediators with various immunological signalling processes, suggests that they are at least partly immune mediated. Another milestone was the finding, in the field of onco-immunology, that local tumor irradiation can modulate the immunogenicity of tumor cells and the anti-tumor immune responsiveness both locally, in the tumor microenvironment, and at systemic level. These observations paved the way for studies exploring optimal combinations of radiotherapy and immunotherapy in order to achieve a synergistic effect to eradicate tumors. However, not all interactions between radiation and the immune system are beneficial, as it was recognized that many of radiation-induced late side effects are also of immune and inflammatory nature. Currently perhaps the most studied field of research in radiation biology is focused around the biological effects of low doses, where many of the observed pathophysiological endpoints are due to mechanisms other than direct radiation-induced cell killing and are immune-related. Finally, it must not be forgotten that the interactions between the ionizing radiations and the immune system are bi-directional, and activation of the immune system also influences the outcome of radiation exposure. This Research Topic brings together 23 articles and aims to give an overview of the complex and very often contradictory nature of the interactions between ionizing radiation and the immune system. Due to its increasing penetrance in the population both through medical diagnostic or environmental sources or during cosmic travel low dose ionizing radiation exposure is becoming a major epidemiological concern world-wide. Several of the articles within the Research Topic specifically address potential long-term health consequences and the underlying mechanisms of low dose radiation exposure. A major intention of the Editors was also to draw the attention of the non-radiobiological scientific community on the fact that ionizing radiation is by far more than purely an immune suppressing agent.
Book Synopsis Radiobiology for the Radiologist by : Eric J. Hall
Download or read book Radiobiology for the Radiologist written by Eric J. Hall and published by Lippincott Williams & Wilkins. This book was released on 2012-03-28 with total page 908 pages. Available in PDF, EPUB and Kindle. Book excerpt: In print since 1972, this seventh edition of Radiobiology for the Radiologist is the most extensively revised to date. It consists of two sections, one for those studying or practicing diagnostic radiolo, nuclear medicine and radiation oncology; the other for those engaged in the study or clinical practice of radiation oncology--a new chapter, on radiologic terrorism, is specifically for those in the radiation sciences who would manage exposed individuals in the event of a terrorist event. The 17 chapters in Section I represent a general introduction to radiation biology and a complete, self-contained course especially for residents in diagnostic radiology and nuclear medicine that follows the Syllabus in Radiation Biology of the RSNA. The 11 chapters in Section II address more in-depth topics in radiation oncology, such as cancer biology, retreatment after radiotherapy, chemotherapeutic agents and hyperthermia. Now in full color, this lavishly illustrated new edition is replete with tables and figures that underscore essential concepts. Each chapter concludes with a "summary of pertinent conclusions" to facilitate quick review and help readers retain important information.
