Quantitative In Vivo Drug Delivery Research Using Magnetic Resonance

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Magnetic Particle Imaging

Author : Tobias Knopp
Publisher : Springer Science & Business Media
ISBN 13 : 364204199X
Total Pages : 211 pages
Book Rating : 4.6/5 (42 download)

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Book Synopsis Magnetic Particle Imaging by : Tobias Knopp

Download or read book Magnetic Particle Imaging written by Tobias Knopp and published by Springer Science & Business Media. This book was released on 2012-05-04 with total page 211 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a comprehensive overview of recent developments in magnetic particle imaging (MPI), a novel imaging modality. Using various static and oscillating magnetic fields, and tracer materials made from iron oxide nanoparticles, MPI can perform background-free measurements of the particles’ local concentration. The method exploits the nonlinear remagnetization behavior of the particles and has the potential to surpass current methods for the detection of iron oxide in terms of sensitivity and spatiotemporal resolution. Starting from an introduction to the technology, the topics addressed include setting up an imaging device, assessment of image quality, development of new MPI tracer materials, and the first preclinical results. This is the first book to be published on magnetic particle imaging, and it will be an invaluable source of information for everyone with an interest in this exciting new modality.

Fluorine Magnetic Resonance Imaging

Author : Ulrich Flogel
Publisher : CRC Press
ISBN 13 : 1315340933
Total Pages : 426 pages
Book Rating : 4.3/5 (153 download)

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Book Synopsis Fluorine Magnetic Resonance Imaging by : Ulrich Flogel

Download or read book Fluorine Magnetic Resonance Imaging written by Ulrich Flogel and published by CRC Press. This book was released on 2016-10-26 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past decade, fluorine (19F) magnetic resonance imaging (MRI) has garnered significant scientific interest in the biomedical research community owing to the unique properties of fluorinated materials and the 19F nucleus. Fluorine has an intrinsically sensitive nucleus for MRI. There is negligible endogenous 19F in the body and thus there is no background signal. Fluorine-containing compounds are ideal tracer labels for a wide variety of MRI applications. Moreover, the chemical shift and nuclear relaxation rate can be made responsive to physiology via creative molecular design. This book is an interdisciplinary compendium that details cutting-edge science and medical research in the emerging field of 19F MRI. Edited by Ulrich Flögel and Eric Ahrens, two prominent MRI researchers, this book will appeal to investigators involved in MRI, biomedicine, immunology, pharmacology, probe chemistry, and imaging physics.

Targeting of Drugs 6

Author : Gregory Gregoriadis
Publisher : Springer Science & Business Media
ISBN 13 : 1489901272
Total Pages : 294 pages
Book Rating : 4.4/5 (899 download)

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Book Synopsis Targeting of Drugs 6 by : Gregory Gregoriadis

Download or read book Targeting of Drugs 6 written by Gregory Gregoriadis and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of a NATO ASI held in Cape Sounion Beach, Greece, June 24-July 5, 1997

In-Vitro and In-Vivo Tools in Drug Delivery Research for Optimum Clinical Outcomes

Author : Ambikanandan Misra
Publisher : CRC Press
ISBN 13 : 1351368710
Total Pages : 341 pages
Book Rating : 4.3/5 (513 download)

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Book Synopsis In-Vitro and In-Vivo Tools in Drug Delivery Research for Optimum Clinical Outcomes by : Ambikanandan Misra

Download or read book In-Vitro and In-Vivo Tools in Drug Delivery Research for Optimum Clinical Outcomes written by Ambikanandan Misra and published by CRC Press. This book was released on 2018-06-22 with total page 341 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the essentials of drug delivery research and provides a unique forum for scientific experimental methods that are exclusively focused by the in-vitro, ex-vivo, and in-vivo methodologies of drug delivery research and felicitates translational research. The book includes recent and novel approaches in evaluation methods of transdermal, nasal, ocular, oral and intraoral, gastro-retentive, colon-targeted, and brain-targeted drug delivery systems. Providing up to date and comprehensive information, this text is invaluable to students, teachers, scientists, and others employed in the field of drug delivery.

Computational Pharmaceutics

Author : Defang Ouyang
Publisher : John Wiley & Sons
ISBN 13 : 1118573978
Total Pages : 350 pages
Book Rating : 4.1/5 (185 download)

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Book Synopsis Computational Pharmaceutics by : Defang Ouyang

Download or read book Computational Pharmaceutics written by Defang Ouyang and published by John Wiley & Sons. This book was released on 2015-05-19 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular modeling techniques have been widely used in drug discovery fields for rational drug design and compound screening. Now these techniques are used to model or mimic the behavior of molecules, and help us study formulation at the molecular level. Computational pharmaceutics enables us to understand the mechanism of drug delivery, and to develop new drug delivery systems. The book discusses the modeling of different drug delivery systems, including cyclodextrins, solid dispersions, polymorphism prediction, dendrimer-based delivery systems, surfactant-based micelle, polymeric drug delivery systems, liposome, protein/peptide formulations, non-viral gene delivery systems, drug-protein binding, silica nanoparticles, carbon nanotube-based drug delivery systems, diamond nanoparticles and layered double hydroxides (LDHs) drug delivery systems. Although there are a number of existing books about rational drug design with molecular modeling techniques, these techniques still look mysterious and daunting for pharmaceutical scientists. This book fills the gap between pharmaceutics and molecular modeling, and presents a systematic and overall introduction to computational pharmaceutics. It covers all introductory, advanced and specialist levels. It provides a totally different perspective to pharmaceutical scientists, and will greatly facilitate the development of pharmaceutics. It also helps computational chemists to look for the important questions in the drug delivery field. This book is included in the Advances in Pharmaceutical Technology book series.

Advances in Nanotechnology Research and Application: 2011 Edition

Author :
Publisher : ScholarlyEditions
ISBN 13 : 1464920583
Total Pages : 8760 pages
Book Rating : 4.4/5 (649 download)

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Book Synopsis Advances in Nanotechnology Research and Application: 2011 Edition by :

Download or read book Advances in Nanotechnology Research and Application: 2011 Edition written by and published by ScholarlyEditions. This book was released on 2012-01-09 with total page 8760 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Nanotechnology Research and Application: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Nanotechnology. The editors have built Advances in Nanotechnology Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Nanotechnology in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Nanotechnology Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

NanoBioMedicine

Author : Shailendra K. Saxena
Publisher : Springer Nature
ISBN 13 : 9813298987
Total Pages : 510 pages
Book Rating : 4.8/5 (132 download)

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Book Synopsis NanoBioMedicine by : Shailendra K. Saxena

Download or read book NanoBioMedicine written by Shailendra K. Saxena and published by Springer Nature. This book was released on 2020-02-03 with total page 510 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of the recent trends in various Nanotechnology-based therapeutics and challenges associated with its development. Nanobiotechnology is an interdisciplinary research that has wide applications in the various fields of biomedical research. The book discusses the various facets of the application of Nanotechnology in drug delivery, clinical diagnostics, Nanomedicine and treatment of infectious and chronic diseases. The book also highlights the recent advancements on important devices and applications that are based on Nanotechnology in medicine and brief the regulatory and ethical issues related to nanomedical devices. It also reviews the toxicological profile of various nanomaterials and emphasizes the need for safe nanomaterials for clinical use. Finally, the book discusses the recent developments of potential commercial applications of Nanotechnology.

Handbook of Small Animal Imaging

Author : George C. Kagadis
Publisher : CRC Press
ISBN 13 : 1315362791
Total Pages : 602 pages
Book Rating : 4.3/5 (153 download)

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Book Synopsis Handbook of Small Animal Imaging by : George C. Kagadis

Download or read book Handbook of Small Animal Imaging written by George C. Kagadis and published by CRC Press. This book was released on 2018-09-03 with total page 602 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use of small animal models in basic and preclinical sciences constitutes an integral part of testing new pharmaceutical agents prior to their application in clinical practice. New imaging and therapeutic approaches need to be tested and validated first in animals before application to humans. Handbook of Small Animal Imaging: Preclinical Imaging, Therapy, and Applications collects the latest information about various imaging and therapeutic technologies used in preclinical research into a single source. Useful to established researchers as well as newcomers to the field, this handbook shows readers how to exploit and integrate these imaging and treatment modalities and techniques into their own research. The book first presents introductory material on small animal imaging, therapy, and research ethics. It next covers ionizing radiation and nonionizing radiation methods in small animal imaging, hybrid imaging, and imaging agents. The book then addresses therapeutic research platforms and image quantification, explaining how to ensure accurate measurements of high-quality data. It concludes with an overview of many small animal imaging and therapy applications that demonstrate the strength of the techniques in biomedical fields.

Alternatives to the Use of Live Vertebrates in Biomedical Research and Testing

Author :
Publisher :
ISBN 13 :
Total Pages : 188 pages
Book Rating : 4.:/5 ( download)

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Book Synopsis Alternatives to the Use of Live Vertebrates in Biomedical Research and Testing by :

Download or read book Alternatives to the Use of Live Vertebrates in Biomedical Research and Testing written by and published by . This book was released on 1996 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Fluorinated Hydrocarbons: Advances in Research and Application: 2011 Edition

Author :
Publisher : ScholarlyEditions
ISBN 13 : 1464940711
Total Pages : 44 pages
Book Rating : 4.4/5 (649 download)

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Book Synopsis Fluorinated Hydrocarbons: Advances in Research and Application: 2011 Edition by :

Download or read book Fluorinated Hydrocarbons: Advances in Research and Application: 2011 Edition written by and published by ScholarlyEditions. This book was released on 2012-01-09 with total page 44 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fluorinated Hydrocarbons: Advances in Research and Application: 2011 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Fluorinated Hydrocarbons in a concise format. The editors have built Fluorinated Hydrocarbons: Advances in Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Fluorinated Hydrocarbons in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Fluorinated Hydrocarbons: Advances in Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Stealth Liposomes

Author : Danilo D. Lasic
Publisher : CRC Press
ISBN 13 : 1351414011
Total Pages : 324 pages
Book Rating : 4.3/5 (514 download)

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Book Synopsis Stealth Liposomes by : Danilo D. Lasic

Download or read book Stealth Liposomes written by Danilo D. Lasic and published by CRC Press. This book was released on 2018-05-04 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book examines stealth liposomes from a multidisciplinary approach, which includes theoretical polymer physics, organic synthesis, colloid science, and biology. Discussions include theory, chemistry, biochemistry, pharmacology, preclinical studies in model systems, and medical applications in humans.

Novel Delivery Systems for Transdermal and Intradermal Drug Delivery

Author : Ryan F. Donnelly
Publisher : John Wiley & Sons
ISBN 13 : 1118734483
Total Pages : 296 pages
Book Rating : 4.1/5 (187 download)

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Book Synopsis Novel Delivery Systems for Transdermal and Intradermal Drug Delivery by : Ryan F. Donnelly

Download or read book Novel Delivery Systems for Transdermal and Intradermal Drug Delivery written by Ryan F. Donnelly and published by John Wiley & Sons. This book was released on 2015-08-07 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: This research book covers the major aspects relating to the use of novel delivery systems in enhancing both transdermal and intradermal drug delivery. It provides a review of transdermal and intradermal drug delivery, including the history of the field and the various methods employed to produce delivery systems from different materials such as device design, construction and evaluation, so as to provide a sound background to the use of novel systems in enhanced delivery applications. Furthermore, it presents in-depth analyses of recent developments in this exponentially growing field, with a focus on microneedle arrays, needle-free injections, nanoparticulate systems and peptide-carrier-type systems. It also covers conventional physical enhancement strategies, such as tape-stripping, sonophoresis, iontophoresis, electroporation and thermal/suction/laser ablation Discussions about the penetration of the stratum corneum by the various novel strategies highlight the importance of the application method. Comprehensive and critical reviews of transdermal and intradermal delivery research using such systems focus on the outcomes of in vivoanimal and human studies. The book includes laboratory, clinical and commercial case studies featuring safety and patient acceptability studies carried out to date, and depicts a growing area for use of these novel systems is in intradermal vaccine delivery. The final chapters review recent patents in this field and describe the work ongoing in industry.

Comprehensive Biomedical Physics

Author :
Publisher : Newnes
ISBN 13 : 0444536337
Total Pages : 4052 pages
Book Rating : 4.4/5 (445 download)

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Book Synopsis Comprehensive Biomedical Physics by :

Download or read book Comprehensive Biomedical Physics written by and published by Newnes. This book was released on 2014-07-25 with total page 4052 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive Biomedical Physics, Ten Volume Set is a new reference work that provides the first point of entry to the literature for all scientists interested in biomedical physics. It is of particularly use for graduate and postgraduate students in the areas of medical biophysics. This Work is indispensable to all serious readers in this interdisciplinary area where physics is applied in medicine and biology. Written by leading scientists who have evaluated and summarized the most important methods, principles, technologies and data within the field, Comprehensive Biomedical Physics is a vital addition to the reference libraries of those working within the areas of medical imaging, radiation sources, detectors, biology, safety and therapy, physiology, and pharmacology as well as in the treatment of different clinical conditions and bioinformatics. This Work will be valuable to students working in all aspect of medical biophysics, including medical imaging and biomedical radiation science and therapy, physiology, pharmacology and treatment of clinical conditions and bioinformatics. The most comprehensive work on biomedical physics ever published Covers one of the fastest growing areas in the physical sciences, including interdisciplinary areas ranging from advanced nuclear physics and quantum mechanics through mathematics to molecular biology and medicine Contains 1800 illustrations, all in full color

Comprehensive Biomaterials II

Author : Kevin Healy
Publisher : Elsevier
ISBN 13 : 0081006926
Total Pages : 4865 pages
Book Rating : 4.0/5 (81 download)

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Book Synopsis Comprehensive Biomaterials II by : Kevin Healy

Download or read book Comprehensive Biomaterials II written by Kevin Healy and published by Elsevier. This book was released on 2017-05-18 with total page 4865 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive Biomaterials II, Second Edition, Seven Volume Set brings together the myriad facets of biomaterials into one expertly-written series of edited volumes. Articles address the current status of nearly all biomaterials in the field, their strengths and weaknesses, their future prospects, appropriate analytical methods and testing, device applications and performance, emerging candidate materials as competitors and disruptive technologies, research and development, regulatory management, commercial aspects, and applications, including medical applications. Detailed coverage is given to both new and emerging areas and the latest research in more traditional areas of the field. Particular attention is given to those areas in which major recent developments have taken place. This new edition, with 75% new or updated articles, will provide biomedical scientists in industry, government, academia, and research organizations with an accurate perspective on the field in a manner that is both accessible and thorough. Reviews the current status of nearly all biomaterials in the field by analyzing their strengths and weaknesses, performance, and future prospects Covers all significant emerging technologies in areas such as 3D printing of tissues, organs and scaffolds, cell encapsulation; multimodal delivery, cancer/vaccine - biomaterial applications, neural interface understanding, materials used for in situ imaging, and infection prevention and treatment Effectively describes the many modern aspects of biomaterials from basic science, to clinical applications

AACR 2018 Proceedings: Abstracts 3028-5930

Author : American Association for Cancer Research
Publisher : CTI Meeting Technology
ISBN 13 : 1370247702
Total Pages : 2995 pages
Book Rating : 4.3/5 (72 download)

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Book Synopsis AACR 2018 Proceedings: Abstracts 3028-5930 by : American Association for Cancer Research

Download or read book AACR 2018 Proceedings: Abstracts 3028-5930 written by American Association for Cancer Research and published by CTI Meeting Technology. This book was released on 2018-04-10 with total page 2995 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Drug Delivery with Targeted Nanoparticles

Author : Yılmaz Çapan
Publisher : CRC Press
ISBN 13 : 1000375307
Total Pages : 654 pages
Book Rating : 4.0/5 (3 download)

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Book Synopsis Drug Delivery with Targeted Nanoparticles by : Yılmaz Çapan

Download or read book Drug Delivery with Targeted Nanoparticles written by Yılmaz Çapan and published by CRC Press. This book was released on 2021-11-30 with total page 654 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanotechnology has the potential to change every part of our lives. Today, nanotechnology-based products are used in many areas, and one of the most important areas is drug delivery. Nanoparticulate drug delivery systems not only provide controlled delivery of drugs and improved drug solubility but also improve drug efficiency and reduce side effects via targeting mechanisms. However, compared with conventional drug delivery systems, few nanoparticle-based products are on the market and almost all are nontargeted or only passively targeted systems. In addition, obtaining targeted nanoparticle systems is quite complex and requires several evaluation mechanisms. This book discusses the production, characterization, regulation, and currently marketed targeted nanoparticle systems in a broad framework. It provides an overview of targeted nanoparticles’ (i) in vitro characterization, such as particle size, stability, ligand density, and type; (ii) in vivo behavior for different targeting areas, such as tumor, brain, and vagina; and (iii) current advances in this field, including clinical trials and regulation processes.

Handbook of Neuro-Oncology Neuroimaging

Author : Herbert B. Newton
Publisher : Academic Press
ISBN 13 : 0128229950
Total Pages : 1022 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Handbook of Neuro-Oncology Neuroimaging by : Herbert B. Newton

Download or read book Handbook of Neuro-Oncology Neuroimaging written by Herbert B. Newton and published by Academic Press. This book was released on 2022-08-21 with total page 1022 pages. Available in PDF, EPUB and Kindle. Book excerpt: With treatment approaches and the field of neuro-oncology neuroimaging changing rapidly, this third edition of the Handbook of Neuro-Oncology Neuroimaging is very relevant to those in the field, providing a single-source, comprehensive, reference handbook of the most up-to-date clinical and technical information regarding the application of neuroimaging techniques to brain tumor and neuro-oncology patients. This new volume will have updates on all of the material from the second edition, and in addition features several new important chapters covering diverse topics such as imaging for the use of Laser Interstitial Thermal Therapy, advanced imaging techniques in radiation therapy, therapeutic treatment fields, response assessment in clinical trials, surgical planning of neoplastic disease of the spine, and more. Sections first overview neuro-oncological disorders before delving into the physics and basic science of neuroimaging and great focus on CT and MRI. The book then focuses on advances in the neuroimaging of brain tumors and neuroimaging of specific tumor types. There is also discussion of neuroimaging of other neuro-oncological syndromes. This book will serve as a resource of background information to neuroimaging researchers and basic scientists with an interest in brain tumors and neuro-oncology. - Summarizes translational research on brain imaging for brain tumors - Discusses limitations of neuroimaging for diagnosis and treatment - Presents advanced imaging technologies, including CT, MRI, and PET - Contains new coverage on Laser Interstitial Thermal Therapy, radiation therapy, clinical trials, and more