Quantitative Genomic Analysis of Agroclimatic Traits in Sorghum

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ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (12 download)

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Book Synopsis Quantitative Genomic Analysis of Agroclimatic Traits in Sorghum by : Olalere Marcus Olatoye

Download or read book Quantitative Genomic Analysis of Agroclimatic Traits in Sorghum written by Olalere Marcus Olatoye and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Climate change has been anticipated to affect agriculture, with most the profound effect in regions where low input agriculture is being practiced. Understanding of how plants evolved in adaptation to diverse climatic conditions in the presence of local stressors (biotic and abiotic) can be beneficial for improved crop adaptation and yield to ensure food security. Great genetic diversity exists for agroclimatic adaptation in sorghum (Sorghum bicolor L. Moench) but much of it has not been characterized. Thus, limiting its utilization in crop improvement. The application of next-generation sequencing has opened the plant genome for analysis to identify patterns of genome-wide nucleotide variations underlying agroclimatic adaptation. To understand the genetic basis of adaptive traits in sorghum, the genetic architecture of sorghum inflorescence traits was characterized in the first study. Phenotypic data were obtained from multi-environment experiments and used to perform joint linkage and genome-wide association mapping. Mapping results identified previously mapped and novel genetic loci underlying inflorescence morphology in sorghum. Inflorescence traits were found to be under the control of a few large and many moderate and minor effect loci. To demonstrate how our understanding of the genetic basis of adaptive traits can facilitate genomic enabled breeding, genomic prediction analysis was performed with results showing high prediction accuracies for inflorescence traits. In the second study, the sorghum-nested association mapping (NAM) population was used to characterize the genetic architecture of leaf erectness, leaf width, and stem diameter. About 2200 recombinant inbred lines were phenotyped in multiple environments. The obtained phenotypic data was used to perform joint linkage mapping using ~93,000 markers. The proportion of phenotypic variation explained by QTL and their allele frequencies were estimated. Common and moderate effects QTL were found to underlie marker-trait associations. Furthermore, identified QTL co-localized with genes involved in both vegetative and inflorescence development. Our results provide insights into the genetic basis of leaf erectness and stem diameter in sorghum. The identified QTL will also facilitate the development of genomic-enable breeding tools for crop improvement and molecular characterization of the underlying genes Finally, in a third study, 607 Nigerian accessions were genotyped and the resulting genomic data [about 190,000 single nucleotide polymorphisms (SNPs)] was used for downstream analysis. Genome-wide scans of selection and genome-wide association studies (GWAS) were performed and alongside estimates of levels of genetic differentiation and genetic diversity. Results showed that phenotypic variation in the diverse germplasm had been shaped by local adaptation across climatic gradient and can provide plant genetic resources for crop improvement.

Genetics, Genomics and Breeding of Sorghum

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Publisher : CRC Press
ISBN 13 : 1482210088
Total Pages : 368 pages
Book Rating : 4.4/5 (822 download)

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Book Synopsis Genetics, Genomics and Breeding of Sorghum by : Yi-Hong Wang

Download or read book Genetics, Genomics and Breeding of Sorghum written by Yi-Hong Wang and published by CRC Press. This book was released on 2014-07-08 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sorghum is one of the hardiest crop plants in modern agriculture and also one of the most versatile. Its seeds provide calorie for food and feed, stalks for building and industrial materials and its juice for syrup. This book provides an in-depth review of the cutting-edge knowledge in sorghum genetics and its applications in sorghum breeding. Each chapter is authored by specialists in their fields to report the latest trends and findings. The book showcases the definitive value of sorghum as a model system to study the genetic basis of crop productivity and stress tolerance and will provide a foundation for future studies in sorghum genetics, genomics, and breeding.

Genomic Mapping for Grain Yield, Stay Green, and Grain Quality Traits in Sorghum

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ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (823 download)

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Book Synopsis Genomic Mapping for Grain Yield, Stay Green, and Grain Quality Traits in Sorghum by : Sivakumar Sukumaran

Download or read book Genomic Mapping for Grain Yield, Stay Green, and Grain Quality Traits in Sorghum written by Sivakumar Sukumaran and published by . This book was released on 2012 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Knowledge of the genetic bases of grain quality traits will complement plant breeding efforts to improve the end use value of sorghum (Sorghum bicolor (L.) Moench). The objective of the first experiment was to assess marker-trait associations for 10 grain quality traits through candidate gene association mapping on a diverse panel of 300 sorghum accessions. The 10 grain quality traits were measured using the single kernel characterization system (SKCS) and near-infrared reflectance spectroscopy (NIRS). The analysis of the accessions through 1,290 genome-wide single nucleotide polymorphisms (SNPs) separated the panel into five subpopulations that corresponded to three major sorghum races (durra, kafir, and caudatum), one intermediate race (guinea-caudatum), and one working group (zerazera/caudatum). Association analysis between 333 SNPs in candidate genes/loci and grain quality traits resulted in eight significant marker-trait associations. A SNP in starch synthase IIa (SSIIa) gene was associated with kernel hardness (KH) with a likelihood ratio-based R2 (R[subscript]L[subscript]R2) value of 0.08. SNPs in starch synthase (SSIIb) gene (R[subscript]L[subscript]R2 = 0.10) and loci pSB1120 (R[subscript]L[subscript]R2 = 0.09) was associated with starch content. Sorghum is a crop well adapted to the semi arid regions of the world and my harbor genes for drought tolerance. The objective of second experiment was to identify quantitative trait loci (QTLs) for yield potential and drought tolerance. From a cross between Tx436 (food grain type) and 00MN7645 (drought tolerant) 248 recombinant inbred lines (RILs) was developed. Multi-location trials were conducted in 8 environments to evaluate agronomic performance of the RILs under favorable and drought stress conditions. The 248 RILs and their parents were genotyped by genotyping-by-sequencing (GBS). A subset of 800 SNPs was used for linkage map construction and QTL detection. Composite interval mapping identified a major QTLs for grain yield in chromosome 8 and QTL for flowering time in chromosome 9 under favorable conditions. Three major QTLs were detected for grain yield in chromosomes 1, 6, and 8 and two flowering time QTLs on chromosome 1 under drought conditions. Six QTLs were identified for stay green: two on chromosome 4; one each on chromosome 5, 6, 7, and 10 under drought conditions.

Sorghum

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Publisher : John Wiley & Sons
ISBN 13 : 0891186271
Total Pages : 528 pages
Book Rating : 4.8/5 (911 download)

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Book Synopsis Sorghum by : Ignacio A. Ciampitti

Download or read book Sorghum written by Ignacio A. Ciampitti and published by John Wiley & Sons. This book was released on 2020-01-22 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sorghum is among the top five cereals and one of the key crops in global food security efforts. Sorghum is a resilient crop under high-stress environments, ensuring productivity and access to food when other crops fail. Scientists see the potential of sorghum as a main staple food in a future challenged by climate change. The contributors provide a comprehensive review of sorghum knowledge. The discussion covers genetic improvements, development of new hybrids, biotechnology, and physiological modifications. Production topics include water and nutrient management, rotations, and pest control. Final end uses, sorghum as a bioenergy crop, markets, and the future of sorghum are presented. IN PRESS! This book is being published according to the “Just Published” model, with more chapters to be published online as they are completed.

Quantitative Trait Loci Affecting the Agronomic Performance of a Sorghum Bicolor (L.) Moench Recombinant Inbred Restorer Line Population

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ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (544 download)

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Book Synopsis Quantitative Trait Loci Affecting the Agronomic Performance of a Sorghum Bicolor (L.) Moench Recombinant Inbred Restorer Line Population by : Jorge Luis Moran Maradiaga

Download or read book Quantitative Trait Loci Affecting the Agronomic Performance of a Sorghum Bicolor (L.) Moench Recombinant Inbred Restorer Line Population written by Jorge Luis Moran Maradiaga and published by . This book was released on 2003 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Lately the rate of genetic gain in most agronomic crop species has been reduced due to several factors that limit breeding efficiency and genetic gain. New genetic tools and more powerful statistical analyses provide an alternative approach to enhance genetic improvements through the identification of molecular markers linked to genomic regions or QTLs controlling quantitative traits. The main objective of this research was to identify genomic regions associated with enhanced agronomic performance in lines per se and hybrid combination in Sorghum bicolor (L.) Moench. A population composed of 187 F5:6 recombinant inbred lines (RIL) was derived from the cross of restorer lines RTx430 and RTx7000. Also, a testcross hybrid population (TCH) was developed by using each RIL as a pollinator onto ATx2752. A linkage map was constructed using 174 marker loci generated from AFLP and SSR primer combinations. These markers were assigned to 12 different linkage groups. The linkage map covers 1573 cM with marker loci spaced at an averaged 9.04 cM. In this study, 89 QTL that control variation in seven different morphological traits were identified in the recombinant inbred line population, while in the testcross hybrid population, 79 QTL were identified. These traits included grain yield, plant height, days to mid-anthesis, panicle number, panicle length, panicle exsertion and panicle weight. These putative QTL explained from 4 to 42% of the phenotypic variation observed for each trait. Many of the QTL were not consistent across populations and across environments. Nevertheless, a few key QTL were identified and the source of the positive additive genetics isolated. RTx7000 was consistently associated with better agronomic performance in RIL, while in testcrosses, RTx430 was. Some genomic regions from RTx7000 may be utilized to improve RTx430 as a line per se. However, it is very unlikely that such regions will have a positive effect on the combining ability of RTx430 since testcross results did not reveal any transgressive segregants from the RIL population.

Lost Crops of Africa

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Publisher : National Academies Press
ISBN 13 : 0309176891
Total Pages : 405 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Lost Crops of Africa by : National Research Council

Download or read book Lost Crops of Africa written by National Research Council and published by National Academies Press. This book was released on 1996-02-14 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scenes of starvation have drawn the world's attention to Africa's agricultural and environmental crisis. Some observers question whether this continent can ever hope to feed its growing population. Yet there is an overlooked food resource in sub-Saharan Africa that has vast potential: native food plants. When experts were asked to nominate African food plants for inclusion in a new book, a list of 30 species grew quickly to hundreds. All in all, Africa has more than 2,000 native grains and fruitsâ€""lost" species due for rediscovery and exploitation. This volume focuses on native cereals, including: African rice, reserved until recently as a luxury food for religious rituals. Finger millet, neglected internationally although it is a staple for millions. Fonio (acha), probably the oldest African cereal and sometimes called "hungry rice." Pearl millet, a widely used grain that still holds great untapped potential. Sorghum, with prospects for making the twenty-first century the "century of sorghum." Tef, in many ways ideal but only now enjoying budding commercial production. Other cultivated and wild grains. This readable and engaging book dispels myths, often based on Western bias, about the nutritional value, flavor, and yield of these African grains. Designed as a tool for economic development, the volume is organized with increasing levels of detail to meet the needs of both lay and professional readers. The authors present the available information on where and how each grain is grown, harvested, and processed, and they list its benefits and limitations as a food source. The authors describe "next steps" for increasing the use of each grain, outline research needs, and address issues in building commercial production. Sidebars cover such interesting points as the potential use of gene mapping and other "high-tech" agricultural techniques on these grains. This fact-filled volume will be of great interest to agricultural experts, entrepreneurs, researchers, and individuals concerned about restoring food production, environmental health, and economic opportunity in sub-Saharan Africa. Selection, Newbridge Garden Book Club

Genetic Analysis of Quantitative Traits in Grain Sorghum (Sorghum Bicolor L. Moench.)

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (756 download)

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Book Synopsis Genetic Analysis of Quantitative Traits in Grain Sorghum (Sorghum Bicolor L. Moench.) by : Patel A U.

Download or read book Genetic Analysis of Quantitative Traits in Grain Sorghum (Sorghum Bicolor L. Moench.) written by Patel A U. and published by . This book was released on 1979 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Genetic Analysis of Some of the Quantitative Characters in Sorghum Bicolor L Moench

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (755 download)

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Book Synopsis Genetic Analysis of Some of the Quantitative Characters in Sorghum Bicolor L Moench by : Dhande P H.

Download or read book Genetic Analysis of Some of the Quantitative Characters in Sorghum Bicolor L Moench written by Dhande P H. and published by . This book was released on 1982 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Physiological, Genetic and Genomic Analyses of Herbicide Resistance in Grain Sorghum (Sorghum Bicolor)

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ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (124 download)

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Book Synopsis Physiological, Genetic and Genomic Analyses of Herbicide Resistance in Grain Sorghum (Sorghum Bicolor) by : Balaji Aravindhan Pandian

Download or read book Physiological, Genetic and Genomic Analyses of Herbicide Resistance in Grain Sorghum (Sorghum Bicolor) written by Balaji Aravindhan Pandian and published by . This book was released on 2020 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Grain sorghum [Sorghum bicolor (L.) Moench ssp. bicolor] is a versatile crop with multiple uses, including for food, feed, and fuel. Postemergence (POST) grass weed control continues to be a major challenge in grain sorghum, primarily due to a lack of herbicide options registered for POST use. The 4- hydroxyphenylpyruvate dioxygenase (HPPD)- (e.g., mesotrione or tembotrione) and acetolactate synthase (ALS)- inhibitor (e.g., chlorsulfuron) herbicides are used for POST control of a broad-spectrum of weeds including grasses in corn and wheat but not in sorghum, due to crop injury. The development of herbicide-resistant sorghum technology to facilitate broad-spectrum POST weed control can be an economical and viable solution. Previously we have identified four sorghum genotypes, two each resistant to mesotrione (G-1 and G-10), tembotrione (G-200 and G-350) and, one susceptible genotype (S-1) from the sorghum association panel. Further, we found that the genotype S-1 is highly resistant to chlorsulfuron. The objectives of this dissertation were to 1) investigate the inheritance, mechanism, and identify genetic loci conferring resistance to mesotrione and tembotrione, 2) characterize, and investigate the inheritance and mechanism of resistance to chlorsulfuron in grain sorghum. To understand the inheritance of the mesotrione and tembotrione resistance, F1 and F2 progeny were generated by performing crosses using S-1 and G-1, G-10, G-200, or G-350. The F1 and F2 progeny were evaluated for their response to various doses of mesotrione and tembotrione treatment. Likewise, chlorsulfuron dose-response experiments were conducted using S-1 along with BTx623, a susceptible check and also F1 and F2 progeny were generated by crossing S-1 and BTx623. The results of genetic analyses of the F1 and F2 progeny demonstrated that the mesotrione resistance in G-1 and G-10 is a single dominant trait, and while the tembotrione resistance in G-200 and G-350 is a partially dominant polygenic trait. Further, sequencing of HPPD gene, the molecular target of mesotrione and tembotrione in the resistant genotypes, revealed no mutations known to bestow resistance. Additionally, the role of cytochrome P450 (CYP) in metabolizing mesotrione and tembotrione, using CYP-inhibitors, malathion and piperonyl butoxide (PBO) was also assessed. The results indicated a significant reduction in biomass accumulation in sorghum plants pre-treated with malathion or PBO, suggesting the involvement of CYPs in the metabolism of mesotrione and tembotrione. Bulk segregation analysis combined with RNA-Seq (BSR-seq) was used to identify the genomic region associated with mesotrione resistance; however, the sequence analyses was unable to map the resistance gene within a smaller interval. Genotype-by-sequencing (GBS) based quantitative trait loci (QTL) mapping revealed three QTLs associated with tembotrione resistance in G-200. The results of the chlorsulfuron dose-response assay indicated that S-1 and F1 progeny were ~20-fold, more resistant to chlorsulfuron relative to BTx623. Segregation of F2 progeny into 3:1 (resistance: susceptibility), suggested that chlorsulfuron resistance in S-1 is a single dominant trait. Sequence analysis of the ALS gene, the molecular target of chlorsulfuron from S-1 revealed no mutations that confer resistance to chlorsulfuron; however, a significant reduction in biomass accumulation was found in plants pre-treated with malathion, indicating that the metabolism of chlorsulfuron contributes to resistance in S-1. Overall, the results of this dissertation provide opportunities to develop herbicide-resistant sorghum hybrids via introgression, which can help effective, POST weed management.

Genetic Analysis of the Sorghum Bicolor Stay-green Drought Tolerance Trait

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ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (662 download)

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Book Synopsis Genetic Analysis of the Sorghum Bicolor Stay-green Drought Tolerance Trait by : Karen Ruth Harris

Download or read book Genetic Analysis of the Sorghum Bicolor Stay-green Drought Tolerance Trait written by Karen Ruth Harris and published by . This book was released on 2010 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Sorghum (Sorghum bicolor [L.] Moench) is the fifth most economically important cereal grown worldwide and is a source of food, feed, fiber and fuel. Sorghum, a C4 grass and a close relative to sugarcane, is adapted to hot, dry adverse environments. Some genotypes of sorghum called stay-green have delayed leaf senescence during grain ripening under drought stress conditions which allows normal grain filling whereas most sorghum lines senesce early under post-anthesis drought. Eight sources of stay-green have been identified in the sorghum germplasm collection, most originating from Sudan and Ethiopia. The diversity of the eight sources of staygreen was analyzed using 55 simple sequence repeats (SSR) markers with genome coverage. This analysis showed that the sources of stay-green are quite diverse and can be divided into five groups based on race or working group. Three sources of stay-green have been used to identify 12 major quantitative trait loci (QTL) that modulate this trait. The origin of favorable alleles for stay-green was traced backward to ancestral lines and forward into breeding materials derived from stay-green germplasm. The analysis of the origin of favorable alleles for stay-green helped explain why subsets of stay-green QTL were identified in different studies and provided evidence that there may be more than one favorable allele in the sorghum germplasm for several of the stay-green QTL. Analysis of stay-green breeding lines from three public sorghum-breeding programs revealed that one of the main QTL identified in mapping studies was not being used in the breeding programs (0/13), most likely due to its association with an allele for lemon yellow seeds. In addition, a subset of the regions containing favorable alleles for staygreen from the genotype BTx642 were over represented in stay-green breeding lines. Nearly isogenic lines containing favorable alleles from BTx642 for Stg1, Stg2, Stg3, and Stg4 in a RTx7000 (senescent) background were characterized and each NIL was shown to exhibit a stay-green phenotype. Based in part on this information, fine-mapping of Stg1 was undertaken by crossing the Stg1 NIL to RTx7000. Overall, these results revealed the origin of favorable alleles for stay-green and the current utilization of alleles for stay-green in public breeding programs. In addition, this study identified additional stay-green sources that could be used for further QTL analysis and highlighted the genetic complexity of the stay-green trait.

Millets and Sorghum

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Publisher : John Wiley & Sons
ISBN 13 : 1119130778
Total Pages : 596 pages
Book Rating : 4.1/5 (191 download)

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Book Synopsis Millets and Sorghum by : Jagannath V. Patil

Download or read book Millets and Sorghum written by Jagannath V. Patil and published by John Wiley & Sons. This book was released on 2016-12-20 with total page 596 pages. Available in PDF, EPUB and Kindle. Book excerpt: Millets and sorghum are extremely important crops in many developing nations and because of the ability of many of them to thrive in low-moisture situations they represent some exciting opportunities for further development to address the continuing and increasing impact of global temperature increase on the sustainability of the world’s food crops. The main focus of this thorough new book is the potential for crop improvement through new and traditional methods, with the book’s main chapters covering the following crops: sorghum, pearl millet, finger millet, foxtail milet, proso millet, little millet, barnyard millet, kodo millet, tef and fonio. Further chapters cover pests and diseases, nutritional and industrial importance, novel tools for improvement, and seed systems in millets. Millets and Sorghum provides full and comprehensive coverage of these crucially important crops, their biology, world status and potential for improvement, and is an essential purchase for crop and plant scientists, and food scientists and technologists throughout the developed and developing world. All libraries in universities and research establishment where biological and agricultural sciences are studied and taught should have copies of this important book on their shelves.

Genomics of the Saccharinae

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Publisher : Springer Science & Business Media
ISBN 13 : 1441959475
Total Pages : 562 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Genomics of the Saccharinae by : Andrew H. Paterson

Download or read book Genomics of the Saccharinae written by Andrew H. Paterson and published by Springer Science & Business Media. This book was released on 2012-09-14 with total page 562 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Saccharinae clade of the Poaceae (grass) family of flowering plants includes several important crops with a rich history of contributions to humanity and the promise of still-greater contributions, as a result of some of the highest biomass productivity levels known, resilience to drought and other environmental challenges that are likely to increase, amenability to production systems that may mitigate or even reverse losses of ecological capital such as topsoil erosion, and the recent blossoming of sorghum as a botanical and genomic model for the clade. In Genomics of the Saccharinae, advances of the past decade and earlier are summarized and synthesized to elucidate the current state of knowledge of the structure, function, and evolution of the Sorghum, Saccharum, and Miscanthus genera, and progress in the application of this knowledge to crop improvement. As a backdrop, it is important to understand the naturally occurring diversity in each genus, its organization and distribution, and its evolutionary history. Genomic tools and methods for Saccharinae biology and improvement have improved dramatically in the past few years – a detailed summary of these tools and their applications is a central element of this book. Application of genomic tools to priorities in crop improvement, including understanding and manipulating plant growth and development, composition, and defense, as well as increasing the quality and productivity of seed/grain, sugar, biomass, and other value-added products under a range of conditions and inputs, are addressed. In particular, as the first native African crop to emerge as a genomic model, sorghum offers an excellent case study of challenges and opportunities in linking new advances in biosciences to solving some of Africa’s major agricultural problems. Several members of the clade, exemplified by Sorghum halepense (Johnsongrass) offer insights into weediness and invasion biology. The first sequence for a member of the clade, sorghum, as well as progress and challenges toward sequencing of additional members and the new opportunities that this will create, are also explored. Indeed, the very complexities that have hindered study of some clade members also offer intriguing opportunities to gain insight into fundamental questions such as roles of polyploidy in agricultural productivity and post-polyploidy evolution.

The Sorghum Genome

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Publisher : Springer
ISBN 13 : 3319477897
Total Pages : 289 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis The Sorghum Genome by : Sujay Rakshit

Download or read book The Sorghum Genome written by Sujay Rakshit and published by Springer. This book was released on 2017-01-18 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides insights into the current state of sorghum genomics. It particularly focuses on the tools and strategies employed in genome sequencing and analysis, public and private genomic resources and how all this information is leading to direct outcomes for plant breeders. The advent of affordable whole genome sequencing in combination with existing cereal functional genomics data has enabled the leveraging of the significant novel diversity available in sorghum, the genome of which was fully sequenced in 2009, providing an unmatched resource for the genetic improvement of sorghum and other grass species. Cultivated grain sorghum is a food and feed cereal crop adapted to hot and dry climates, and is a staple for 500 million of the world’s poorest people. Globally, sorghum is also an important source of animal feed and forage, an emerging biofuel crop and model for C4 grasses, particularly genetically complex sugarcane.

Sorghum Molecular Breeding

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Publisher : Springer
ISBN 13 : 8132224221
Total Pages : 231 pages
Book Rating : 4.1/5 (322 download)

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Book Synopsis Sorghum Molecular Breeding by : R. Madhusudhana

Download or read book Sorghum Molecular Breeding written by R. Madhusudhana and published by Springer. This book was released on 2015-08-20 with total page 231 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an up-to-date overview of international research work on sorghum. Its comprehensive coverage of our current understanding of transgenic development in sorghum and the strategies that are being applied in molecular breeding make this book unique. Important areas such as genetic diversity, QTL mapping, heterosis prediction, genomic and bioinformatics resources, post-genome sequencing developments, molecular markers development using bioinformatics tools, genetic transformation and transgenic research are also addressed. The availability of the genome sequence along with other recent developments in sequencing and genotyping technologies has resulted in considerable advances in the area of sorghum genomics. These in turn have led to the generation of a large number of DNA-based markers and resulted in the identification and fine mapping of QTL associated with grain yield, its component traits, biotic and abiotic stress tolerance as well as grain quality traits in sorghum. Though a large volume of information has accumulated over the years, especially following the sequencing of the sorghum genome, until now it was not available in a single reference resource. This book fills that gap by documenting advances in the genomics and transgenic research in sorghum and presenting critical reviews and future prospects. “Sorghum Molecular Breeding” is an essential guide for students, researchers and managers who are involved in the area of molecular breeding and transgenic research in sorghum and plant biologists in general.

Bayesian Methods in Structural Bioinformatics

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Publisher : Springer
ISBN 13 : 3642272258
Total Pages : 399 pages
Book Rating : 4.6/5 (422 download)

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Book Synopsis Bayesian Methods in Structural Bioinformatics by : Thomas Hamelryck

Download or read book Bayesian Methods in Structural Bioinformatics written by Thomas Hamelryck and published by Springer. This book was released on 2012-03-23 with total page 399 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is an edited volume, the goal of which is to provide an overview of the current state-of-the-art in statistical methods applied to problems in structural bioinformatics (and in particular protein structure prediction, simulation, experimental structure determination and analysis). It focuses on statistical methods that have a clear interpretation in the framework of statistical physics, rather than ad hoc, black box methods based on neural networks or support vector machines. In addition, the emphasis is on methods that deal with biomolecular structure in atomic detail. The book is highly accessible, and only assumes background knowledge on protein structure, with a minimum of mathematical knowledge. Therefore, the book includes introductory chapters that contain a solid introduction to key topics such as Bayesian statistics and concepts in machine learning and statistical physics.

Genomic Designing of Climate-Smart Cereal Crops

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Publisher : Springer Nature
ISBN 13 : 3319933817
Total Pages : 321 pages
Book Rating : 4.3/5 (199 download)

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Book Synopsis Genomic Designing of Climate-Smart Cereal Crops by : Chittaranjan Kole

Download or read book Genomic Designing of Climate-Smart Cereal Crops written by Chittaranjan Kole and published by Springer Nature. This book was released on 2020-02-28 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book highlights modern methods and strategies to improve cereal crops in the era of climate change, presenting the latest advances in plant molecular mapping and genome sequencing. Spectacular achievements in the fields of molecular breeding, transgenics and genomics in the last three decades have facilitated revolutionary changes in cereal- crop-improvement strategies and techniques. Since the genome sequencing of rice in 2002, the genomes of over eight cereal crops have been sequenced and more are to follow. This has made it possible to decipher the exact nucleotide sequence and chromosomal positions of agroeconomic genes. Most importantly, comparative genomics and genotyping-by-sequencing have opened up new vistas for exploring available biodiversity, particularly of wild crop relatives, for identifying useful donor genes.

The Applications of New Multi-Locus GWAS Methodologies in the Genetic Dissection of Complex Traits

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Publisher : Frontiers Media SA
ISBN 13 : 2889458342
Total Pages : 236 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis The Applications of New Multi-Locus GWAS Methodologies in the Genetic Dissection of Complex Traits by : Yuan-Ming Zhang

Download or read book The Applications of New Multi-Locus GWAS Methodologies in the Genetic Dissection of Complex Traits written by Yuan-Ming Zhang and published by Frontiers Media SA. This book was released on 2019-06-19 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genome-Wide Association Studies (GWAS) are widely used in the genetic dissection of complex traits. Most existing methods are based on single-marker association in genome-wide scans with population structure and polygenic background controls. To control the false positive rate, the Bonferroni correction for multiple tests is frequently adopted. This stringent correction results in the exclusion of important loci, especially for GWAS in crop genetics. To address this issue, multi-locus GWAS methodologies have been recommended, i.e., FASTmrEMMA, ISIS EM-BLASSO, mrMLM, FASTmrMLM, pLARmEB, pKWmEB and FarmCPU. In this Research Topic, our purpose is to clarify some important issues in the application of multi-locus GWAS methods. Here we discuss the following subjects: First, we discuss the advantages of new multi-locus GWAS methods over the widely-used single-locus GWAS methods in the genetic dissection of complex traits, metabolites and gene expression levels. Secondly, large experiment error in the field measurement of phenotypic values for complex traits in crop genetics results in relatively large P-values in GWAS, indicating the existence of small number of significantly associated SNPs. To solve this issue, a less stringent P-value critical value is often adopted, i.e., 0.001, 0.0001 and 1/m (m is the number of markers). Although lowering the stringency with which an association is made could identify more hits, confidence in these hits would significantly drop. In this Research Topic we propose a new threshold of significant QTN (LOD=3.0 or P-value=2.0e-4) in multi-locus GWAS to balance high power and low false positive rate. Thirdly, heritability missing in GWAS is a common phenomenon, and a series of scientists have explained the reasons why the heritability is missing. In this Research Topic, we also add one additional reason and propose the joint use of several GWAS methodologies to capture more QTNs. Thus, overall estimated heritability would be increased. Finally, we discuss how to select and use these multi-locus GWAS methods.