Quantitative Computed Tomography Based Bone Strength Indicators For The Identification Of Low Bone Strength Individuals In A Clinical Environment

Download Quantitative Computed Tomography Based Bone Strength Indicators For The Identification Of Low Bone Strength Individuals In A Clinical Environment full books in PDF, epub, and Kindle. Read online Quantitative Computed Tomography Based Bone Strength Indicators For The Identification Of Low Bone Strength Individuals In A Clinical Environment ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!

Quantitative Computed-tomography Based Bone-strength Indicators for the Identification of Low Bone-strength Individuals in a Clinical Environment

Author : Bino Abel Varghese
Publisher :
ISBN 13 :
Total Pages : 85 pages
Book Rating : 4.:/5 (11 download)

DOWNLOAD NOW!

Book Synopsis Quantitative Computed-tomography Based Bone-strength Indicators for the Identification of Low Bone-strength Individuals in a Clinical Environment by : Bino Abel Varghese

Download or read book Quantitative Computed-tomography Based Bone-strength Indicators for the Identification of Low Bone-strength Individuals in a Clinical Environment written by Bino Abel Varghese and published by . This book was released on 2011 with total page 85 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of the current study was to develop quantitative computed-tomography (QCT)-based bone-strength indicators that highly correlate with finite-element (FE)-based strength. We perform a combined numerical-experimental study, comparing FE-predicted surface strains with strain gauge measurements, to validate the FE models of 36 long bones (humerus, radius, femur and tibia) under three-point bending and torsion. The FE models were constructed from trans-axial volumetric CT scans, and the segmented bone images were corrected for partial-volume effects. The material properties (Young's modulus for cortex, density-modulus relationship for trabecular bone and Poisson's ratio) were calibrated by minimizing the error between experiments and simulations among all bones. The resultant R2 values of the measured strains versus load under three-point bending and torsion were 0.96-0.99 and 0.61-0.99, respectively, for all bones in our data set. The errors of the calculated FE strains in comparison to those measured using strain gauges in the mechanical tests ranged from -6% to 7% under bending and from -37% to 19% under torsion. The observation of comparatively low errors and high correlations between the FE-predicted strains and the experimental strains, across the various types of bones and loading conditions (bending and torsion), validates our approach to bone segmentation and our choice of material properties. Based on the analysis of the various FE models of the long bones, the location of the CT slice on the bone that showed the highest propensity to fracture was identified for four loading conditions (compression, three-point bending, cantilever bending and torsion). The identified CT slice was then used to derive novel and improved bone-strength indicators. We evaluated the performance of area-weighted (AW), density-weighted (DW) and modulus-weighted (MW) rigidity measures as well as popular strength indicators like section modulus and stress-strain index. We have also developed a novel strength metric, the centroid deviation, which takes into consideration the spatial distribution of the centroids. Here, we observed that the MW polar moment of inertia and the MW moment of inertia were the two top-performers (average r

Bone Health Assessment in Pediatrics

Author : Ellen B. Fung
Publisher : Springer
ISBN 13 : 3319304127
Total Pages : 355 pages
Book Rating : 4.3/5 (193 download)

DOWNLOAD NOW!

Book Synopsis Bone Health Assessment in Pediatrics by : Ellen B. Fung

Download or read book Bone Health Assessment in Pediatrics written by Ellen B. Fung and published by Springer. This book was released on 2016-09-09 with total page 355 pages. Available in PDF, EPUB and Kindle. Book excerpt: The gold-standard resource for evaluating bone health in children and adolescents, this practical and highly anticipated second edition offers a comprehensive, fully updated resource for addressing bone health in these populations. Developed by a renowned international panel of experts in measuring and analyzing bone density in the pediatric patient and reflecting the 2013 International Society for Clinical Densitometry (ISCD) Guidelines for Pediatric DXA assessment, interpretation and reporting, this indispensable reference covers all the important changes in the field over the last 9 years. Some highlights of this edition include: an entire chapter on the assessment of infants and toddlers, a chapter devoted to the assessment of children with disabling conditions, an in-depth discussion of vertebral fracture and its etiologies, and a thorough review of the advantages and limitations of densitometry techniques including DXA, pQCT, HRpQCT, and MRI. New fracture prediction software, including Trabecular Bone Score and Finite Element Analysis, is described. In this edition, the limitations of DXA are addressed as are the most recent strategies for handling them including proposed DXA adjustments such as height Z-score. Solidifying itself as the leading text in the field, Bone Health Assessment in Pediatrics: Guidelines for Clinical Practice, 2nd edition provides all of the critical basic analysis and evaluation tools, images, and calculations necessary for clinical practice.

Quantitative Methods in Bone Densitometry

Author : Alan Huddleston
Publisher : Springer Science & Business Media
ISBN 13 : 1461317258
Total Pages : 223 pages
Book Rating : 4.4/5 (613 download)

DOWNLOAD NOW!

Book Synopsis Quantitative Methods in Bone Densitometry by : Alan Huddleston

Download or read book Quantitative Methods in Bone Densitometry written by Alan Huddleston and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt: Interest in bone densitometry methods has recently experienced a resurgence within the medical community. Physicians have become more interested than ever before in the diagnosis and treatment of degenerative diseases of bone such as osteoporosis. The public perception of osteoporosis and its prevention has been recently heightened. Because osteoporosis is widespread, especially in women, and leads to an increase in fractures in our population, many re searchers and clinicians are strongly motivated in their search for more sensi tive and accurate methods of diagnosis. This book was written for physicians, scientists, engineers, medical phy sicists, and others desiring an introduction or further understanding of this exciting field. Beginning with the early development of x-ray film methods for assessing bone status, the field has steadily grown throughout the years. Novel and interesting devices have been designed for the measurement of bone mass, bone density, cortical thickness, and other parameters of bone changes. Both qualitative and quantitative bone methods are described. The techniques include imaging devices such as CT and radiography as well as fixed point methods in which bone characteristics of a region of interest are analyzed.

Performance Analysis of Quantitative Bone Measurement with Spiral, Multi-detector CT Scanners

Author : Shruti Gupta
Publisher :
ISBN 13 :
Total Pages : 175 pages
Book Rating : 4.:/5 (1 download)

DOWNLOAD NOW!

Book Synopsis Performance Analysis of Quantitative Bone Measurement with Spiral, Multi-detector CT Scanners by : Shruti Gupta

Download or read book Performance Analysis of Quantitative Bone Measurement with Spiral, Multi-detector CT Scanners written by Shruti Gupta and published by . This book was released on 2008 with total page 175 pages. Available in PDF, EPUB and Kindle. Book excerpt: The measure of bone strength and fracture risk assessment is based primarily on bone mineral density (BMD). Computed tomography (CT), a frequently used radiographic technique that provides cross-sectional images, can be used for BMD quantification. Called quantitative computed tomography (QCT), it determines true volumetric density and also differentiates between trabecular and cortical bone. As a result, QCT improves the ability to detect early changes in trabecular BMD accurately and precisely. The introduction of helical CT for quantitative analysis introduces new complexities. Even though using multi-detector helical CT for BMD assessment is being suggested, a detailed analysis of its validity is missing from the literature. The current project exhaustively considers the various aspects of the problem. First, a detailed overview of the problems incurred while using multi-detector helical scanning for QCT is given and a suite of tests to evaluate MSCT machines is introduced. For this purpose a rod phantom was designed to mimic a patient, with various amounts of bone, and scans of the rod phantom along with the Mindways calibration phantom were taken using multi-detector spiral CT scanners from the three major CT scanner manufacturers General Electric (GE), Siemens and Toshiba. 4-, 16- and 64-slice scanners were used for the study. Except for the 16/64 slice Siemens scanners, an underlying cyclic pattern was observed in the data collected using the remaining 4 scanners in this study. Depending on the interpolation algorithm, the frequency of this pattern was either equal to or half of the total number of detector arrays. The numbers for precision, in mg/cc, returned from this experiment were within the range of 0.0053 – 7.8121 mg/cc. Variations of the density with pitch were small and did not extend the precision range specified by the previous experiments. Spanning the entire allowable scan table length, a shift ranging from 0.0022 to 9.3 HU and 0.0013 to 15.02 mg/cc was observed for the GE and Siemens CT scanners when transitioning to the table extension. For the Toshiba scanner, the shifts in the range of 61 to 479 HU were reduced to 0.63 to 9.73 mg/cc after calibration. The table-height experiment revealed that the CT numbers and hence the calibrated densities are a function of the position of the object being scanned within the gantry. The change in the densities with table height is reduced after calibration, with the low-density ROIs being an exception. An averaging calibration method to take into account the cyclic repetition appears to be reasonable to allow for reduced errors using spiral CT for quantitative bone analysis. Even though the calibration method compensates for the variations because of table position and height, scanning close to the isocenter within the gantry and avoiding inclusion of the table extension in the scan field of view will be beneficial. Spiral CT can be used for quantitative purposes by carefully setting the scan protocol and applying proper corrections.

Peripheral Quantitative Computed Tomography to Assess Bone Density, Geometry and Strength

Author : Charles A. Wisniewski
Publisher :
ISBN 13 :
Total Pages : 102 pages
Book Rating : 4.:/5 (79 download)

DOWNLOAD NOW!

Book Synopsis Peripheral Quantitative Computed Tomography to Assess Bone Density, Geometry and Strength by : Charles A. Wisniewski

Download or read book Peripheral Quantitative Computed Tomography to Assess Bone Density, Geometry and Strength written by Charles A. Wisniewski and published by . This book was released on 2010 with total page 102 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Advances in Imaging Technology Research and Application: 2012 Edition

Author :
Publisher : ScholarlyEditions
ISBN 13 : 1464990794
Total Pages : 1612 pages
Book Rating : 4.4/5 (649 download)

DOWNLOAD NOW!

Book Synopsis Advances in Imaging Technology Research and Application: 2012 Edition by :

Download or read book Advances in Imaging Technology Research and Application: 2012 Edition written by and published by ScholarlyEditions. This book was released on 2012-12-26 with total page 1612 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Imaging Technology Research and Application / 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Imaging Technology. The editors have built Advances in Imaging Technology Research and Application / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Imaging Technology in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Imaging Technology Research and Application / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Proceedings of All India Seminar on Biomedical Engineering 2012 (AISOBE 2012)

Author : Veerendra Kumar
Publisher : Springer Science & Business Media
ISBN 13 : 8132209702
Total Pages : 294 pages
Book Rating : 4.1/5 (322 download)

DOWNLOAD NOW!

Book Synopsis Proceedings of All India Seminar on Biomedical Engineering 2012 (AISOBE 2012) by : Veerendra Kumar

Download or read book Proceedings of All India Seminar on Biomedical Engineering 2012 (AISOBE 2012) written by Veerendra Kumar and published by Springer Science & Business Media. This book was released on 2012-11-02 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a collection of articles presented by researchers and practitioners, including engineers, biologists, health professionals and informatics/computer scientists, interested in both theoretical advances and applications of information systems, artificial intelligence, signal processing, electronics and other engineering tools in areas related to biology and medicine in the All India Seminar on Biomedical Engineering 2012 (AISOBE 2012), organized by The Institution of Engineers (India), Jabalpur Local Centre, Jabalpur, India during November 3-4, 2012. The content of the book is useful to doctors, engineers, researchers and academicians as well as industry professionals.

Bone Health and Osteoporosis

Author : United States Public Health Service
Publisher :
ISBN 13 : 9781410219275
Total Pages : 0 pages
Book Rating : 4.2/5 (192 download)

DOWNLOAD NOW!

Book Synopsis Bone Health and Osteoporosis by : United States Public Health Service

Download or read book Bone Health and Osteoporosis written by United States Public Health Service and published by . This book was released on 2004-12 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This first-ever Surgeon General's Report on bone health and osteoporosis illustrates the large burden that bone disease places on our Nation and its citizens. Like other chronic diseases that disproportionately affect the elderly, the prevalence of bone disease and fractures is projected to increase markedly as the population ages. If these predictions come true, bone disease and fractures will have a tremendous negative impact on the future well-being of Americans. But as this report makes clear, they need not come true: by working together we can change the picture of aging in America. Osteoporosis, fractures, and other chronic diseases no longer should be thought of as an inevitable part of growing old. By focusing on prevention and lifestyle changes, including physical activity and nutrition, as well as early diagnosis and appropriate treatment, Americans can avoid much of the damaging impact of bone disease and other chronic diseases. This Surgeon General's Report brings together for the first time the scientific evidence related to the prevention, assessment, diagnosis, and treatment of bone disease. More importantly, it provides a framework for moving forward. The report will be another effective tool in educating Americans about how they can promote bone health throughout their lives. This first-ever Surgeon General's Report on bone health and osteoporosis provides much needed information on bone health, an often overlooked aspect of physical health. This report follows in the tradition of previous Surgeon Generals' reports by identifying the relevant scientific data, rigorously evaluating and summarizing the evidence, and determining conclusions.

Radiology of Osteoporosis

Author : Stephan Grampp
Publisher : Springer Science & Business Media
ISBN 13 : 3662052350
Total Pages : 204 pages
Book Rating : 4.6/5 (62 download)

DOWNLOAD NOW!

Book Synopsis Radiology of Osteoporosis by : Stephan Grampp

Download or read book Radiology of Osteoporosis written by Stephan Grampp and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt: Due to the aging population in the Western world, osteoporosis has become a major problem which is of interest to several medical disciplines: not only radiologists but also gynecologists, endocrinologists, rheumatologists, and orthopedic surgeons are involved in the management of this widespread condition. Functional imaging is becoming rapidly an important area of diagnostic radiology. Imaging of osteoporosis is another application of this recent addition to the armory of radiology. It is important that radiologists should be fully aware of the range of diagnostic modalities-conventional radiologic methods, dual X-ray absorptiometry, quantitative computed tomography, quantitative ultrasound, magnetic resonance imaging, etc. -that are now available for the diagnosis and the follow-up of osteoporosis, and know how to apply these sophisticated methods in daily clinical practice. Dr. S. Grampp is a radiologist with a longstanding interest in osteoporosis, and his previous publications on this condition are internationally known. He has been very successful in engaging several outstandingly qualified experts to contribute to the indi vidual chapters of this superb book, which provides a omprehensive c overview of our current knowledge of osteoporosis. I am confident that this volume will meet with great interest from radiologists and all other clinicians involved in the care of patients with osteoporosis and will encounter the same success as many previous volumes in this series.

Fundamentals of Medical Imaging

Author : Paul Suetens
Publisher : Cambridge University Press
ISBN 13 : 1139479881
Total Pages : 265 pages
Book Rating : 4.1/5 (394 download)

DOWNLOAD NOW!

Book Synopsis Fundamentals of Medical Imaging by : Paul Suetens

Download or read book Fundamentals of Medical Imaging written by Paul Suetens and published by Cambridge University Press. This book was released on 2009-08-06 with total page 265 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fundamentals of Medical Imaging, second edition, is an invaluable technical introduction to each imaging modality, explaining the mathematical and physical principles and giving a clear understanding of how images are obtained and interpreted. Individual chapters cover each imaging modality – radiography, CT, MRI, nuclear medicine and ultrasound – reviewing the physics of the signal and its interaction with tissue, the image formation or reconstruction process, a discussion of image quality and equipment, clinical applications and biological effects and safety issues. Subsequent chapters review image analysis and visualization for diagnosis, treatment and surgery. New to this edition: • Appendix of questions and answers • New chapter on 3D image visualization • Advanced mathematical formulae in separate text boxes • Ancillary website containing 3D animations: www.cambridge.org/suetens • Full colour illustrations throughout Engineers, clinicians, mathematicians and physicists will find this an invaluable aid in understanding the physical principles of imaging and their clinical applications.

The Aging Skeleton

Author : Clifford Rosen
Publisher : Elsevier
ISBN 13 : 0080542379
Total Pages : 667 pages
Book Rating : 4.0/5 (85 download)

DOWNLOAD NOW!

Book Synopsis The Aging Skeleton by : Clifford Rosen

Download or read book The Aging Skeleton written by Clifford Rosen and published by Elsevier. This book was released on 1999-08-19 with total page 667 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Aging Skeleton is a comprehensive and timely book on all aspects of the skeleton as it ages, including basic mechanisms and pathways as well as pathobiology. Chapters cover general aspects and models of aging, determinants and maintenance of peak bone mass, mechanisms of age-related bone loss, quantifiable manifestations of age-related bone loss, fractures, and therapeutics. Covers all aspects of the aging skeleton in one comprehensive volume Looks at the influence of genetics, nutrition, environment, hormones, and other factors on bone mass Provides a thorough discussion of fractures, one of the major consequences of the aging skeleton Reviews current therapeutic approaches and methods Written by internationally renowned authors and edited by leaders in the field Is the only book available on this subject

Osteoporosis in Men

Author : Eric S. Orwoll
Publisher : Academic Press
ISBN 13 : 0080923461
Total Pages : 764 pages
Book Rating : 4.0/5 (89 download)

DOWNLOAD NOW!

Book Synopsis Osteoporosis in Men by : Eric S. Orwoll

Download or read book Osteoporosis in Men written by Eric S. Orwoll and published by Academic Press. This book was released on 2009-11-30 with total page 764 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the publication of the first edition, the U.S. Surgeon General released the first-ever report on bone health and osteoporosis in October 2004. This report focuses even more attention on the devastating impact osteoporosis has on millions of lives. According to the National Osteoporosis Foundation, 2 million American men have osteoporosis, and another 12 million are at risk for this disease. Yet despite the large number of men affected, the lack of awareness by doctors and their patients puts men at a higher risk that the condition may go undiagnosed and untreated. It is estimated that one-fifth to one-third of all hip fractures occur in men. This second edition brings on board John Bilezikian and Dirk Vanderschueren as editors with Eric Orwoll. The table of contents is more than doubling with 58 planned chapters. The format is larger – 8.5 x 11. This edition of Osteoporosis in Men brings together even more eminent investigators and clinicians to interpret developments in this growing field, and describe state-of-the-art research as well as practical approaches to diagnosis, prevention and therapy. Brings together more eminent investigators and clinicians to interpret developments in this growing field Describes state-of-the-art research as well as practical approaches to diagnosis, prevention and therapy There is no book on the market that covers osteoporosis in men as comprehensively as this book

Quantitative Ultrasound

Author : Thomas Fuerst PhD
Publisher : CRC Press
ISBN 13 : 9781853176791
Total Pages : 432 pages
Book Rating : 4.1/5 (767 download)

DOWNLOAD NOW!

Book Synopsis Quantitative Ultrasound by : Thomas Fuerst PhD

Download or read book Quantitative Ultrasound written by Thomas Fuerst PhD and published by CRC Press. This book was released on 1999-10-13 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ultrasound is quickly becoming the technique of choice in the measurement of bone density. Proving cheaper and more portable than previous techniques, and also having the advantage of not using ionizing radiation, it is likely that the use of various ultrasound systems will become increasingly widespread in clinical practice. This book is a comprehensive review of the systems currently available, preceded by a summary of the basic science of ultrasound and concluding with a section on clinical studies, trials and experience in a number of countries. Likely future developments are also discussed, bringing the book completely up to date.

Bone Stress Injuries

Author : Adam S. Tenforde, MD
Publisher : Springer Publishing Company
ISBN 13 : 0826144241
Total Pages : 219 pages
Book Rating : 4.8/5 (261 download)

DOWNLOAD NOW!

Book Synopsis Bone Stress Injuries by : Adam S. Tenforde, MD

Download or read book Bone Stress Injuries written by Adam S. Tenforde, MD and published by Springer Publishing Company. This book was released on 2021-07-17 with total page 219 pages. Available in PDF, EPUB and Kindle. Book excerpt: “This book gives a nice summary of the current state of diagnosis, treatment, and prevention of bone stress injuries. It is particularly useful for sports medicine fellows and residents with an interest in athletes and active patients." ---Doody's Review Service, 3 stars Bone stress injuries are commonly seen in athletes and active individuals across a full spectrum of physical activity, age, and gender. While most overuse injuries can be addressed through non-operative care, injuries may progress to full fractures that require surgery if misdiagnosed or not correctly managed. Written by leaders in sports medicine including physical medicine and rehabilitation, orthopaedics, endocrinology and allied health professionals of biomechanics, physical therapy and dietetics, Bone Stress Injuries offers state-of-the-art guidelines and up-to-date science and terminology to practitioners. Using a holistic approach to understand the management of bone stress injuries, this book highlights specific considerations by injury, gender, and risk factor to ensure that a comprehensive treatment plan can be developed to optimize bone health, neuromuscular re-education, gait mechanics, and injury prevention. Organized into four parts, opening chapters cover the general need-to-know topics, including clinical history, imaging, and risk factors including biological and biomechanical factors. The book proceeds anatomically through the body from upper extremity to foot and ankle injuries, with each chapter underscoring diagnostic and treatment strategies specific to that region. Chapters dedicated to special populations discuss the differences in injury evaluation and management according to age, gender, and military background. Final chapters review the prevention of injuries and examine both common and novel treatment strategies, such as medications, nutrition, gait retraining, orthobiologics, and other interventions. Invaluable in its scope and approach, Bone Stress Injuries is the go-to resource for sports medicine physicians, physiatrists, and primary care providers who manage the care of athletes and individuals leading active lifestyles. Key Features: Promotes evidence-based practice for diagnosis, treatment, and prevention of bone stress injuries Covers specific anatomy that is prone to bone stress injuries with dedicated chapters on upper and lower extremities, pelvis and hip, spine, and foot and ankle Considers evaluation and management differences according to specific populations of pediatric, male, female, and military personnel Discusses emerging strategies to treat bone stress injuries, such as gait retraining, orthobiologics, and other non-pharmacological treatments

Pocket Reference to Osteoporosis

Author : Serge Livio Ferrari
Publisher : Springer
ISBN 13 : 3319267574
Total Pages : 98 pages
Book Rating : 4.3/5 (192 download)

DOWNLOAD NOW!

Book Synopsis Pocket Reference to Osteoporosis by : Serge Livio Ferrari

Download or read book Pocket Reference to Osteoporosis written by Serge Livio Ferrari and published by Springer. This book was released on 2018-12-28 with total page 98 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book responds to the daily needs of all clinicians treating patients with osteoporosis and provides a key reference guide for any challenges that arise in clinical practice. This book also covers the genetics of the disease, clinical presentation, diagnosis, and current and upcoming treatment recommendations in accordance with the latest international guidelines. Osteoporosis is a disease in which the density and quality of bone are greatly reduced, and as bones become more porous and fragile the risk of fracture increases greatly. It is one of the most common metabolic bone diseases globally with one in three women and one in five men at risk of an osteoporotic fracture, and can result in devastating physical, psychosocial, and economic consequences. However, in spite of this osteoporosis can often be overlooked and undertreated, thus there is a real need to raise awareness of this disease.

Biomarkers in Bone Disease

Author : Victor R. Preedy
Publisher : Springer
ISBN 13 : 9789400776920
Total Pages : 0 pages
Book Rating : 4.7/5 (769 download)

DOWNLOAD NOW!

Book Synopsis Biomarkers in Bone Disease by : Victor R. Preedy

Download or read book Biomarkers in Bone Disease written by Victor R. Preedy and published by Springer. This book was released on 2017-07-14 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past decade there has been a major sea change in the way disease is diagnosed and investigated due to the advent of high throughput technologies, such as microarrays, lab on a chip, proteomics, genomics, lipomics, metabolomics etc. These advances have enabled the discovery of new and novel markers of disease relating to autoimmune disorders, cancers, endocrine diseases, genetic disorders, sensory damage, intestinal diseases etc. In many instances these developments have gone hand in hand with the discovery of biomarkers elucidated via traditional or conventional methods, such as histopathology or clinical biochemistry. Together with microprocessor-based data analysis, advanced statistics and bioinformatics these markers have been used to identify individuals with active disease or pathology as well as those who are refractory or have distinguishing pathologies. New analytical methods that have been used to identify markers of disease and is suggested that there may be as many as 40 different platforms. Unfortunately techniques and methods have not been readily transferable to other disease states and sometimes diagnosis still relies on single analytes rather than a cohort of markers. There is thus a demand for a comprehensive and focused evidenced-based text and scientific literature that addresses these issues. Hence the formulation of Biomarkers in Disease. The series covers a wide number of areas including for example, nutrition, cancer, endocrinology, cardiology, addictions, immunology, birth defects, genetics, and so on. The chapters are written by national or international experts and specialists.

Strengthening Forensic Science in the United States

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309142393
Total Pages : 348 pages
Book Rating : 4.3/5 (91 download)

DOWNLOAD NOW!

Book Synopsis Strengthening Forensic Science in the United States by : National Research Council

Download or read book Strengthening Forensic Science in the United States written by National Research Council and published by National Academies Press. This book was released on 2009-07-29 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scores of talented and dedicated people serve the forensic science community, performing vitally important work. However, they are often constrained by lack of adequate resources, sound policies, and national support. It is clear that change and advancements, both systematic and scientific, are needed in a number of forensic science disciplines to ensure the reliability of work, establish enforceable standards, and promote best practices with consistent application. Strengthening Forensic Science in the United States: A Path Forward provides a detailed plan for addressing these needs and suggests the creation of a new government entity, the National Institute of Forensic Science, to establish and enforce standards within the forensic science community. The benefits of improving and regulating the forensic science disciplines are clear: assisting law enforcement officials, enhancing homeland security, and reducing the risk of wrongful conviction and exoneration. Strengthening Forensic Science in the United States gives a full account of what is needed to advance the forensic science disciplines, including upgrading of systems and organizational structures, better training, widespread adoption of uniform and enforceable best practices, and mandatory certification and accreditation programs. While this book provides an essential call-to-action for congress and policy makers, it also serves as a vital tool for law enforcement agencies, criminal prosecutors and attorneys, and forensic science educators.